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Sir Stanley Peart was a clinician and clinical researcher who made a major contribution to our understanding of blood pressure regulation. He was the first to demonstrate the release of noradrenaline in response to sympathetic nerve stimulation. He was also the first to purify, and determine the structure of, angiotensin and he later isolated the enzyme, renin, and carried out many important investigations of the factors controlling its release in the body. This year, the essay topic was \u201cIs Essential Hypertension really Primary or Essential?\u201d. In her prize-winning essay, Victoria Dahmen questions the continued use of the term \u201cessential hypertension\u201d suggesting that it may obscure the complex and often modifiable factors contributing to elevated blood pressure. By exploring the roles of salt sensitivity, obesity, and their physiological interplay, her essay calls for a more nuanced, mechanism-based classification of hypertension. Such a shift, she argues, will facilitate clinicians to deliver personalised medicine by aligning medical language with modern scientific understanding.<\/jats:p>","DOI":"10.1038\/s41371-025-01066-w","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T11:59:40Z","timestamp":1757505580000},"page":"679-682","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Linguistics of Hypertension: Is \u201cEssential\u201d Really Primary, or Just Plain Complex?"],"prefix":"10.1038","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8105-6034","authenticated-orcid":false,"given":"Victoria D.","family":"Dahmen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"1066_CR1","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1161\/01.CIR.101.3.329","volume":"101","author":"OA Carretero","year":"2000","unstructured":"Carretero OA, Oparil S. 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Professor Peter Sever has received consultation fees for scientific advisory boards and lectures from Viatris. Dr Luca Faconti, Dr Helen Warren, Dr Ryan McNally and Ms Victoria Dahmen have no competing interests to declare.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Ethical approval was not required for this work as it did not involve any human or animal studies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}