{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T09:21:25Z","timestamp":1794216085232,"version":"4.8.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["5\/4\/1-33\/2020-NCD-1"],"award-info":[{"award-number":["5\/4\/1-33\/2020-NCD-1"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Hum Hypertens"],"DOI":"10.1038\/s41371-026-01204-y","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T11:49:48Z","timestamp":1788004188000},"page":"873-879","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Global DNA methylation and hypertension control Vis-\u00c0-Vis lipids: an exploratory population based study from rural Punjab, India"],"prefix":"10.1038","volume":"40","author":[{"given":"Debashis","family":"Bhattacharjee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suniti","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naorem Kiranmala","family":"Devi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram Prasad","family":"Mitra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjita","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kewal","family":"Krishan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajinder Kumar","family":"Dhamija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-9675","authenticated-orcid":false,"given":"Kallur Nava","family":"Saraswathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,29]]},"reference":[{"key":"1204_CR1","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.14.04172","volume":"14","author":"B Liu","year":"2024","unstructured":"Liu B, Lin X, Meng T, Tian P, Chen L, Zhang H, et al. Global prevalence and disability-adjusted life years of hypertensive heart disease: A trend analysis from the Global Burden of Disease Study 2019. J Glob Health. 2024;14:04172 https:\/\/doi.org\/10.7189\/jogh.14.04172","journal-title":"J Glob Health"},{"key":"1204_CR2","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1161\/CIRCRESAHA.120.318729","volume":"128","author":"AE Schutte","year":"2021","unstructured":"Schutte AE, Srinivasapura Venkateshmurthy N, Mohan S, Prabhakaran D. Hypertension in low- and middle-income countries. Circ Res. 2021;128:808\u201326. https:\/\/doi.org\/10.1161\/CIRCRESAHA.120.318729","journal-title":"Circ Res"},{"key":"1204_CR3","doi-asserted-by":"publisher","first-page":"e2339098","DOI":"10.1001\/jamanetworkopen.2023.39098","volume":"6","author":"JS Varghese","year":"2023","unstructured":"Varghese JS, Venkateshmurthy NS, Sudharsanan N, Jeemon P, Patel SA, Thirumurthy H, et al. Hypertension diagnosis, treatment, and control in India. JAMA Network Open. 2023;6:e2339098 https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.39098","journal-title":"JAMA Network Open"},{"key":"1204_CR4","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1111\/joim.13352","volume":"290","author":"KJ Olczak","year":"2021","unstructured":"Olczak KJ, Taylor-Bateman V, Nicholls HL, Traylor M, Cabrera CP, Munroe PB. Hypertension genetics past, present and future applications. J Intern Med. 2021;290:1130\u201352. https:\/\/doi.org\/10.1111\/joim.13352","journal-title":"J Intern Med"},{"key":"1204_CR5","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1038\/s41371-021-00644-y","volume":"36","author":"E Shams","year":"2022","unstructured":"Shams E, Kamalumpundi V, Peterson J, Gismondi RA, Oigman W, de Gusm\u00e3o Correia ML. Highlights of mechanisms and treatment of obesity-related hypertension. J Hum Hypertens. 2022;36:785\u201393. https:\/\/doi.org\/10.1038\/s41371-021-00644-y","journal-title":"J Hum Hypertens"},{"key":"1204_CR6","doi-asserted-by":"publisher","first-page":"1849","DOI":"10.1001\/jama.2022.19590","volume":"328","author":"RM Carey","year":"2022","unstructured":"Carey RM, Moran AE, Whelton PK. Treatment of hypertension: a review. JAMA. 2022;328:1849\u201361. https:\/\/doi.org\/10.1001\/jama.2022.19590","journal-title":"JAMA"},{"key":"1204_CR7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s40119-019-00159-1","volume":"9","author":"B Williams","year":"2020","unstructured":"Williams B, Masi S, Wolf J, Schmieder RE. Facing the challenge of lowering blood pressure and cholesterol in the same patient: report of a symposium at the European Society of Hypertension. Cardiol Ther. 2020;9:19\u201334. https:\/\/doi.org\/10.1007\/s40119-019-00159-1","journal-title":"Cardiol Ther"},{"key":"1204_CR8","first-page":"138","volume":"69","author":"S Koba","year":"2011","unstructured":"Koba S, Hirano T. Dyslipidemia and atherosclerosis. Nihon Rinsho. Japn J Clin Med. 2011;69:138\u201343.","journal-title":"Nihon Rinsho. Japn J Clin Med"},{"key":"1204_CR9","doi-asserted-by":"publisher","first-page":"5888","DOI":"10.15829\/1560-4071-2024-5888","volume":"29","author":"AV Sineglazova","year":"2024","unstructured":"Sineglazova AV, Fakhrutdinova AS, Kim TY, Parve SD. Lipitension and cardiometabolic risk factors in young people. Russ J Cardiol. 2024;29:5888 https:\/\/doi.org\/10.15829\/1560-4071-2024-5888","journal-title":"Russ J Cardiol"},{"key":"1204_CR10","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.895499","volume":"10","author":"S Chen","year":"2022","unstructured":"Chen S, Cheng W. Relationship between lipid profiles and hypertension: a cross-sectional study of 62,957 Chinese adult males. Front Public Health. 2022;10:895499 https:\/\/doi.org\/10.3389\/fpubh.2022.895499","journal-title":"Front Public Health"},{"key":"1204_CR11","doi-asserted-by":"publisher","first-page":"776","DOI":"10.3390\/nu17050776","volume":"17","author":"H Berisha","year":"2025","unstructured":"Berisha H, Hattab R, Comi L, Giglione C, Migliaccio S, Magni P. Nutrition and lifestyle interventions in managing dyslipidemia and cardiometabolic risk. Nutrients. 2025;17:776 https:\/\/doi.org\/10.3390\/nu17050776","journal-title":"Nutrients"},{"key":"1204_CR12","doi-asserted-by":"publisher","first-page":"4738","DOI":"10.1007\/s10528-023-10659-4","volume":"62","author":"V Chaudhary","year":"2024","unstructured":"Chaudhary V, Bhattacharjee D, Devi NK, Saraswathy KN. Global DNA methylation levels Viz-a-Viz genetic and biochemical variations in one carbon metabolic pathway: an exploratory study from North India. Biochem Genet. 2024;62:4738\u201354. https:\/\/doi.org\/10.1007\/s10528-023-10659-4","journal-title":"Biochem Genet"},{"key":"1204_CR13","doi-asserted-by":"publisher","first-page":"e0227728","DOI":"10.1371\/journal.pone.0227728","volume":"15","author":"N Kazmi","year":"2020","unstructured":"Kazmi N, Elliott HR, Burrows K, Tillin T, Hughes AD, Chaturvedi N, et al. Associations between high blood pressure and DNA methylation. PLoS ONE. 2020;15:e0227728 https:\/\/doi.org\/10.1371\/journal.pone.0227728","journal-title":"PLoS ONE"},{"key":"1204_CR14","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.plipres.2016.10.002","volume":"64","author":"KV Braun","year":"2016","unstructured":"Braun KV, Voortman T, Dhana K, Troup J, Bramer WM, Troup J, et al. The role of DNA methylation in dyslipidaemia: A systematic review. Prog Lipid Res. 2016;64:178\u201391. https:\/\/doi.org\/10.1016\/j.plipres.2016.10.002","journal-title":"Prog Lipid Res"},{"key":"1204_CR15","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glae167","volume":"79","author":"Z Wan","year":"2024","unstructured":"Wan Z, Chibnik LB, Valeri L, Hughes TM, Blacker D, Ma Y. DNA methylation mediates the association between cardiometabolic risk factors and cognition: findings from the health and retirement study. J Gerontol Series A, Biol Sci Med Sci. 2024;79:glae167 https:\/\/doi.org\/10.1093\/gerona\/glae167","journal-title":"J Gerontol Series A, Biol Sci Med Sci"},{"key":"1204_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-018-1601-3","volume":"19","author":"LT Husquin","year":"2018","unstructured":"Husquin LT, Rotival M, Fagny M, Quach H, Zidane N, McEwen LM, et al. Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation. Genome Biol. 2018;19:222 https:\/\/doi.org\/10.1186\/s13059-018-1601-3","journal-title":"Genome Biol"},{"key":"1204_CR17","doi-asserted-by":"publisher","first-page":"31","DOI":"10.2147\/IBPC.S272548","volume":"14","author":"N Desai","year":"2021","unstructured":"Desai N, Unni G, Agarwala R, Salagre S, Godbole S, Dengra A, et al. Risk factors and comorbidities in young indian patients with hypertension: REAL YOUNG (Hypertension) study. Integr Blood Press Control. 2021;14:31\u201341. https:\/\/doi.org\/10.2147\/IBPC.S272548","journal-title":"Integr Blood Press Control"},{"key":"1204_CR18","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-021-00895-1","volume":"14","author":"S Yadav","year":"2021","unstructured":"Yadav S, Longkumer I, Joshi S, Saraswathy KN. Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India. BMC Med Genomics. 2021;14:59 https:\/\/doi.org\/10.1186\/s12920-021-00895-1","journal-title":"BMC Med Genomics"},{"key":"1204_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-77437-z","volume":"14","author":"A Kaushik","year":"2024","unstructured":"Kaushik A, Bhattacharjee D, Chaudhary V, Dahal S, Devi NK, Mitra RP, et al. Hypertension and global DNA methylation: a population-based study in rural, Punjab, India. Sci Rep. 2024;14:25826 https:\/\/doi.org\/10.1038\/s41598-024-77437-z","journal-title":"Sci Rep"},{"key":"1204_CR20","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.70186","volume":"37","author":"TS Singh","year":"2025","unstructured":"Singh TS, Devi NK, Saraswathy KN, Mitra RP, Pandey R, Lalnuneng A. Obesity in low- and middle-income countries: sex-specific sociocultural determinants in high-risk rural Punjab, India. Am J Hum Biol. 2025;37:e70186 https:\/\/doi.org\/10.1002\/ajhb.70186","journal-title":"Am J Hum Biol"},{"key":"1204_CR21","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.2147\/COPD.S141295","volume":"12","author":"JU Lim","year":"2017","unstructured":"Lim JU, Lee JH, Kim JS, Hwang YI, Kim TH, Lim SY, et al. Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients. Int J Chron Obstruct Pulmon Dis. 2017;12:2465\u201375. https:\/\/doi.org\/10.2147\/COPD.S141295","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"1204_CR22","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1111\/j.1751-7176.2009.00179.x","volume":"11","author":"TD Giles","year":"2009","unstructured":"Giles TD, Materson BJ, Cohn JN, Kostis JB. Definition and classification of hypertension: an update. J Clin Hypertension (Greenwich, Conn.). 2009;11:611\u20134. https:\/\/doi.org\/10.1111\/j.1751-7176.2009.00179.x","journal-title":"J Clin Hypertension (Greenwich, Conn.)"},{"key":"1204_CR23","doi-asserted-by":"publisher","first-page":"e96808","DOI":"10.1371\/journal.pone.0096808","volume":"9","author":"SR Joshi","year":"2014","unstructured":"Joshi SR, Anjana RM, Deepa M, Pradeepa R, Bhansali A, Dhandania VK, et al. Prevalence of dyslipidemia in urban and rural India: the ICMR-INDIAB study. PLoS ONE. 2014;9:e96808 https:\/\/doi.org\/10.1371\/journal.pone.0096808","journal-title":"PLoS ONE"},{"key":"1204_CR24","first-page":"1813","volume":"16","author":"JN Gaaib","year":"2011","unstructured":"Gaaib JN, Nassief AF, Al-Assi A. Simple salting-out method for genomic DNA extraction from whole blood. Tikrit J Pure Sci. 2011;16:1813\u2013662.","journal-title":"Tikrit J Pure Sci"},{"key":"1204_CR25","doi-asserted-by":"publisher","DOI":"10.2174\/1573403X16999201210200342","volume":"17","author":"A Alloubani","year":"2021","unstructured":"Alloubani A, Nimer R, Samara R. Relationship between hyperlipidemia, cardiovascular disease and stroke: a systematic review. Curr Cardiol Rev. 2021;17:e051121189015 https:\/\/doi.org\/10.2174\/1573403X16999201210200342","journal-title":"Curr Cardiol Rev"},{"key":"1204_CR26","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.1007\/s40200-022-01114-z","volume":"21","author":"S Khanmohammadi","year":"2022","unstructured":"Khanmohammadi S, Tavolinejad H, Aminorroaya A, Rezaie Y, Ashraf H, Vasheghani-Farahani A. Association of lipid accumulation product with type 2 diabetes mellitus, hypertension, and mortality: a systematic review and meta-analysis. J Diabetes Metab Disord. 2022;21:1943\u201373. https:\/\/doi.org\/10.1007\/s40200-022-01114-z","journal-title":"J Diabetes Metab Disord"},{"key":"1204_CR27","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1186\/s10020-020-00220-z","volume":"26","author":"T P\u0142atek","year":"2020","unstructured":"P\u0142atek T, Polus A, G\u00f3ralska J, Ra\u017any U, Gruca A, Kie\u0107-Wilk B, et al. DNA methylation microarrays identify epigenetically regulated lipid related genes in obese patients with hypercholesterolemia. Molecular Med (Cambridge, Mass.). 2020;26:93 https:\/\/doi.org\/10.1186\/s10020-020-00220-z","journal-title":"Molecular Med (Cambridge, Mass.)"},{"key":"1204_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.681649","volume":"12","author":"S Andrade","year":"2021","unstructured":"Andrade S, Morais T, Sandovici I, Seabra AL, Const\u00e2ncia M, Monteiro MP. Adipose tissue epigenetic profile in obesity-related dysglycemia - a systematic review. Front Endocrinol. 2021;12:681649 https:\/\/doi.org\/10.3389\/fendo.2021.681649","journal-title":"Front Endocrinol"},{"key":"1204_CR29","first-page":"24","volume":"13","author":"A Yahyapour","year":"2025","unstructured":"Yahyapour A, Balou F, Hadizadeh M, Yaghoobi MM. Epigenetic mechanisms affecting the development of atherosclerosis: a narrative review. J Cardio-Thoracic Med. 2025;13:24.","journal-title":"J Cardio-Thoracic Med"},{"key":"1204_CR30","doi-asserted-by":"publisher","first-page":"170","DOI":"10.3390\/biomedicines10010170","volume":"10","author":"L Ho","year":"2022","unstructured":"Ho L, Hossen N, Nguyen T, Vo A, Ahsan F. Epigenetic mechanisms as emerging therapeutic targets and microfluidic chips application in pulmonary arterial hypertension. Biomedicines. 2022;10:170 https:\/\/doi.org\/10.3390\/biomedicines10010170","journal-title":"Biomedicines"},{"key":"1204_CR31","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1007\/s11892-008-0037-7","volume":"8","author":"M Deshmukh","year":"2008","unstructured":"Deshmukh M, Lee HW, McFarlane SI, Whaley-Connell A. Antihypertensive medications and their effects on lipid metabolism. Curr Diab Rep. 2008;8:214\u201320. https:\/\/doi.org\/10.1007\/s11892-008-0037-7","journal-title":"Curr Diab Rep"},{"key":"1204_CR32","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1111\/j.1524-6175.2007.07161.x","volume":"9","author":"DA Sica","year":"2007","unstructured":"Sica DA. Centrally acting antihypertensive agents: an update. J Clin Hypertension (Greenwich, Conn.). 2007;9:399\u2013405. https:\/\/doi.org\/10.1111\/j.1524-6175.2007.07161.x","journal-title":"J Clin Hypertension (Greenwich, Conn.)"},{"key":"1204_CR33","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1007\/s40292-022-00507-8","volume":"29","author":"C Borghi","year":"2022","unstructured":"Borghi C, Fogacci F, Agnoletti D, Cicero AFG. Hypertension and dyslipidemia combined therapeutic approaches. High Blood Press Cardiovasc Prev. 2022;29:221\u201330. https:\/\/doi.org\/10.1007\/s40292-022-00507-8","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"1204_CR34","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s11883-021-00965-w","volume":"23","author":"AC Jones","year":"2021","unstructured":"Jones AC, Irvin MR, Claas SA, Arnett DK. Lipid phenotypes and DNA methylation: a review of the literature. Curr Atheroscler Rep. 2021;23:71 https:\/\/doi.org\/10.1007\/s11883-021-00965-w","journal-title":"Curr Atheroscler Rep"},{"key":"1204_CR35","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1161\/CIRCRESAHA.123.322135","volume":"132","author":"AA Baccarelli","year":"2023","unstructured":"Baccarelli AA, Ordov\u00e1s J. Epigenetics of early cardiometabolic disease: mechanisms and precision medicine. Circ Res. 2023;132:1648\u201362. https:\/\/doi.org\/10.1161\/CIRCRESAHA.123.322135","journal-title":"Circ Res"},{"key":"1204_CR36","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.pharmthera.2018.11.001","volume":"195","author":"A Unnikrishnan","year":"2019","unstructured":"Unnikrishnan A, Freeman WM, Jackson J, Wren JD, Porter H, Richardson A. The role of DNA methylation in epigenetics of aging. Pharmacol Ther. 2019;195:172\u201385. https:\/\/doi.org\/10.1016\/j.pharmthera.2018.11.001","journal-title":"Pharmacol Ther"},{"key":"1204_CR37","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/B978-0-12-803309-8.00024-0","volume-title":"Genome stability","author":"D Zhou","year":"2016","unstructured":"Zhou D, Robertson KD. Role of DNA methylation in genome stability. Genome stability. Academic Press; 2016. p. 409\u201324."},{"key":"1204_CR38","unstructured":"Feingold, KR, Grunfeld, C (2025). Effect of Inflammation and Infection on Lipids and Lipoproteins. In KR Feingold (Eds.) et. al., Endotext. MDText.com, Inc."},{"key":"1204_CR39","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1093\/ije\/dys020","volume":"41","author":"MS Pearce","year":"2012","unstructured":"Pearce MS, McConnell JC, Potter C, Barrett LM, Parker L, Mathers JC, et al. Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles. Int J Epidemiol. 2012;41:210\u20137. https:\/\/doi.org\/10.1093\/ije\/dys020","journal-title":"Int J Epidemiol"},{"key":"1204_CR40","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1007\/s11883-017-0673-y","volume":"19","author":"S Zaina","year":"2017","unstructured":"Zaina S, Lund G. Connecting the dots between fatty acids, mitochondrial function, and DNA methylation in atherosclerosis. Curr Atheroscler Rep. 2017;19:36 https:\/\/doi.org\/10.1007\/s11883-017-0673-y","journal-title":"Curr Atheroscler Rep"},{"key":"1204_CR41","doi-asserted-by":"publisher","DOI":"10.1038\/srep25867","volume":"6","author":"C de la Rocha","year":"2016","unstructured":"de la Rocha C, P\u00e9rez-Mojica JE, Le\u00f3n SZ, Cervantes-Paz B, Trist\u00e1n-Flores FE, Rodr\u00edguez-R\u00edos D, et al. Associations between whole peripheral blood fatty acids and DNA methylation in humans. Sci Rep. 2016;6:25867 https:\/\/doi.org\/10.1038\/srep25867","journal-title":"Sci Rep"},{"key":"1204_CR42","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1126\/science.1083557","volume":"300","author":"A Eden","year":"2003","unstructured":"Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science (New York, N.Y.). 2003;300:455 https:\/\/doi.org\/10.1126\/science.1083557","journal-title":"Science (New York, N.Y.)"},{"key":"1204_CR43","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1007\/s11883-023-01132-z","volume":"25","author":"E D\u0105browska","year":"2023","unstructured":"D\u0105browska E, Narkiewicz K. Hypertension and dyslipidemia: the two partners in endothelium-related crime. Curr Atheroscler Rep. 2023;25:605 https:\/\/doi.org\/10.1007\/s11883-023-01132-z","journal-title":"Curr Atheroscler Rep"},{"key":"1204_CR44","doi-asserted-by":"publisher","first-page":"1936","DOI":"10.1161\/ATVBAHA.113.301765","volume":"33","author":"A Kumar","year":"2013","unstructured":"Kumar A, Kumar S, Vikram A, Hoffman TA, Naqvi A, Lewarchik CM, et al. Histone and DNA methylation-mediated epigenetic downregulation of endothelial Kruppel-like factor 2 by low-density lipoprotein cholesterol. Arterioscler Thromb Vasc Biol. 2013;33:1936\u201342. https:\/\/doi.org\/10.1161\/ATVBAHA.113.301765","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["Journal of Human Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41371-026-01204-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41371-026-01204-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41371-026-01204-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T08:21:33Z","timestamp":1794212493000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41371-026-01204-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,29]]},"references-count":44,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,11]]}},"alternative-id":["1204"],"URL":"https:\/\/doi.org\/10.1038\/s41371-026-01204-y","relation":{},"ISSN":["1476-5527"],"issn-type":[{"value":"1476-5527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,29]]},"assertion":[{"value":"17 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the institutional ethical committee, Department of Anthropology, University of Delhi, Delhi-110007, India. Approval number: Anth.\/2018\/2890\/28-12-18.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Ethics"}}]}}