{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:00:26Z","timestamp":1791903626567,"version":"4.3.4"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T00:00:00Z","timestamp":1542067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1038\/s41372-018-0269-6","type":"journal-article","created":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T10:20:38Z","timestamp":1542104438000},"page":"229-236","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Lowest PaCO2 on the first day of life predicts mortality and morbidity among infants with congenital diaphragmatic hernia"],"prefix":"10.1038","volume":"39","author":[{"name":"for the Congenital Diaphragmatic Hernia Study Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minal J.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2366-1843","authenticated-orcid":false,"given":"Cynthia S.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin P.","family":"Lally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela A.","family":"Lally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi I.","family":"Katakam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,11,13]]},"reference":[{"key":"269_CR1","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.jpedsurg.2006.10.043","volume":"42","author":"CM Schultz","year":"2007","unstructured":"Schultz CM, DiGeronimo RJ, Yoder BA. Congenital diaphragmatic hernia: a simplified postnatal predictor of outcome. J Pediatr Surg. 2007;42:510\u20136.","journal-title":"J Pediatr Surg"},{"key":"269_CR2","first-page":"97","volume":"44","author":"RN Haricharan","year":"2009","unstructured":"Haricharan RN, Barnhart DC, Cheng H, Delzell E. Identifying neonates at a very high risk for mortality among children with congenital diaphragmatic hernia managed with extracorporeal membrane oxygenation. J Pediatr Surg. 2009;44:97\u201393.","journal-title":"J Pediatr Surg"},{"key":"269_CR3","doi-asserted-by":"publisher","first-page":"2214","DOI":"10.1016\/j.jpedsurg.2013.03.049","volume":"48","author":"AJ Coleman","year":"2013","unstructured":"Coleman AJ, Brozanski B, Mahmood B, Wearden PD, Potoka D, Kuch BA. First 24-h SNAP-II score and highest PaCO2 predict the need for ECMO in congenital diaphragmatic hernia. J Pediatr Surg. 2013;48:2214\u20138.","journal-title":"J Pediatr Surg"},{"key":"269_CR4","doi-asserted-by":"publisher","first-page":"924","DOI":"10.3346\/jkms.2013.28.6.924","volume":"28","author":"HW Park","year":"2013","unstructured":"Park HW, Lee BS, Lim G, Choi Y, Kim EA, Kim K. A simplified formula using early blood gas analysis can predict survival outcomes and the requirements for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Korean Med Sci. 2013;28:924\u20138.","journal-title":"J Korean Med Sci"},{"key":"269_CR5","doi-asserted-by":"publisher","first-page":"e413","DOI":"10.1542\/peds.2013-3367","volume":"134","author":"ME Brindle","year":"2014","unstructured":"Brindle ME, Cook EF, Tibboel D, Lally PA, Lally KP, Congenital Diaphragmatic Hernia Study Group. A Clinical prediction rule for the severity of congenital diaphragmatic hernias in newborns. Pediatrics. 2014;134:e413\u20139.","journal-title":"Pediatrics"},{"key":"269_CR6","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/jp.2017.11","volume":"37","author":"K Terui","year":"2017","unstructured":"Terui K, Nagata K, Kanamori Y, Takahashi S, Hayakawa M, Okuyama H, et al. Risk stratification for congenital diaphragmatic hernia by factors within 24h after birth. J Perinatol. 2017;37:805\u20138.","journal-title":"J Perinatol"},{"key":"269_CR7","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/S0022-3468(84)80350-4","volume":"19","author":"DJ Bohn","year":"1984","unstructured":"Bohn DJ, James I, Filler RM, Ein SH, Wesson DE, Shandling B, et al. The relationship between PaCO2 and ventilation parameters in predicting survival in congenital diaphragmatic hernia. J Pediatr Surg. 1984;19:666\u201371.","journal-title":"J Pediatr Surg"},{"key":"269_CR8","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1016\/S0022-3468(96)90036-6","volume":"31","author":"JF Germain","year":"1996","unstructured":"Germain JF, Farnoux C, Pinquier D, Cortez A, Hartmann JF, Sibony O, et al. Can blood gas values predict pulmonary hypoplasia in antenatally diagnosed congenital diaphragmatic hernia? J Pediatr Surg. 1996;31:1634\u20139.","journal-title":"J Pediatr Surg"},{"key":"269_CR9","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1055\/s-0034-1368088","volume":"31","author":"AA Salas","year":"2014","unstructured":"Salas AA, Bhat R, Dabrowska K, Leadford A, Anderson S, Harmon CM, et al. The value of PaCO2 in relation to outcome in congenital diaphragmatic hernia. Am J Perinatol. 2014;31:939\u201346.","journal-title":"Am J Perinatol"},{"key":"269_CR10","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1016\/j.jpedsurg.2014.03.011","volume":"49","author":"AY Khmour","year":"2014","unstructured":"Khmour AY, Konduri GG, Sato TT, Uhing MR, Basir MA. Role of admission gas exchange measurement in predicting congenital diaphragmatic hernia survival in the era of gentle ventilation. J Pediatr Surg. 2014;49:1197\u2013201.","journal-title":"J Pediatr Surg"},{"key":"269_CR11","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.jpedsurg.2015.02.028","volume":"50","author":"PI Abbas","year":"2015","unstructured":"Abbas PI, Cass DI, Olutoye OO, Zamora IJ, Akinkuotu AC, Sheik F, et al. Persistent hypercarbia after resuscitation is associated with increased mortality in congenital diaphragmatic hernia patients. J Pediatr Surg. 2015;50:739\u201343.","journal-title":"J Pediatr Surg"},{"key":"269_CR12","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.jpedsurg.2015.03.005","volume":"50","author":"DW Kays","year":"2015","unstructured":"Kays DW, Islam S, Perkins JM, Larson SD, Taylor JA, Talbert JL. Outcomes in the physiologically most severe congenital diaphragmatic hernia (CDH) patients: Whom should we treat? J Pediatr Surg. 2015;50:893\u20137.","journal-title":"J Pediatr Surg"},{"key":"269_CR13","doi-asserted-by":"crossref","unstructured":"Grizelj R, Bojanic K, Pritisanac E, Luetic T, Vukovic J, Weingarten TN, et al. Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases. BMC Pediatr 2016; 16.","DOI":"10.1186\/s12887-016-0658-y"},{"key":"269_CR14","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1053\/j.sempedsurg.2007.01.009","volume":"16","author":"P Bagolan","year":"2007","unstructured":"Bagolan P, Morini F. Long-term follow up in infants with congenital diaphragmatic hernia. Semin Pediatr Surg. 2007;16:134\u201344.","journal-title":"Semin Pediatr Surg"},{"key":"269_CR15","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/j.jpedsurg.2014.12.007","volume":"50","author":"RP Cauley","year":"2015","unstructured":"Cauley RP, Potanos K, Fullington N, Bairdain S, Sheils CA, Finkelstein JA, et al. Pulmonary support on day of life 30 is a strong predictor of increased 1 and 5-year morbidity in survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2015;50:849\u201355.","journal-title":"J Pediatr Surg"},{"key":"269_CR16","doi-asserted-by":"crossref","unstructured":"Bruns AS, Lau PE, Dhillon GS, Hagan J, Kailin JA, Mallory GB, et al. Predictive value of oxygenation index for outcome in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2018;53:1675\u201380.","DOI":"10.1016\/j.jpedsurg.2017.12.023"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41372-018-0269-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41372-018-0269-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41372-018-0269-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:27:34Z","timestamp":1684618054000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41372-018-0269-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,13]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["269"],"URL":"https:\/\/doi.org\/10.1038\/s41372-018-0269-6","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,13]]},"assertion":[{"value":"27 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}