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The primary outcomes were UC migration, discontinuation due to malposition, and CLABSI incidence. Differences between groups were statistically analyzed and logistic regression used to adjust for potential confounders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 118 neonates (57 LifeBubble, 61 adhesive), LifeBubble significantly reduced migration of any UC\u2009&gt;\u20091 vertebral body (12.3% vs. 55.7%), including UVC migration (5.3% vs. 39.3%) and UAC migration (7.0% vs 23.0%), as well as UVC discontinuation due to malposition (5.6% vs 37.7%). The number needed to treat (NNT) to prevent one instance of UVC discontinuation is 4.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LifeBubble effectively reduces UC migration and premature discontinuation, indicating its potential to enhance neonatal care and safety.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1038\/s41372-024-01943-1","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T08:02:08Z","timestamp":1711180928000},"page":"1359-1364","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Reducing umbilical catheter migration rates by using a novel securement device"],"prefix":"10.1038","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7792-8427","authenticated-orcid":false,"given":"Juliana R.","family":"Perl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6064-8343","authenticated-orcid":false,"given":"Tanya","family":"Crabtree-Beach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Olyaei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline","family":"Hedges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1553-8503","authenticated-orcid":false,"given":"Brian K.","family":"Jordan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0207-9624","authenticated-orcid":false,"given":"Brian","family":"Scottoline","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"key":"1943_CR1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.aucc.2021.02.010","volume":"35","author":"K Gibson","year":"2022","unstructured":"Gibson K, Sharp R, Ullman A, Morris S, Kleidon T, Esterman A. 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