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Urine total protein (median [interquartile range]) in FGR-SGA was higher 370 [323, 573] vs 255 [193, 453] mg\/L in AGA, <jats:italic>P<\/jats:italic>\u2009=\u20090.017 at first assessment (week one) and 565 [445, 743] vs 225 [135, 458] mg\/L, <jats:italic>P<\/jats:italic>\u2009=\u20090.0011 at second assessment (week four). Urine protein creatinine ratio was 393 [250, 445] in FGR-SGA vs 227 [163, 367] mg\/mmol in AGA, <jats:italic>P<\/jats:italic>\u2009=\u20090.029 at first assessment and 444 [368, 699] vs 240 [199, 411] mg\/mmol, <jats:italic>P<\/jats:italic>\u2009=\u20090.0014 at second assessment. Mean blood pressure was higher in FGR-SGA group &amp; directly correlated with proteinuria.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Increased proteinuria in FGR-SGA suggests reduced nephron endowment and hyper-filtration.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1038\/s41372-025-02306-0","type":"journal-article","created":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T05:10:13Z","timestamp":1745039413000},"page":"1469-1475","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Proteinuria in preterm neonates: influence of fetal growth restriction"],"prefix":"10.1038","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2600-7529","authenticated-orcid":false,"given":"Arvind","family":"Sehgal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Criona","family":"Levins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7426-1973","authenticated-orcid":false,"given":"Emma","family":"Yeomans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4478-5308","authenticated-orcid":false,"given":"David","family":"Metz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,19]]},"reference":[{"key":"2306_CR1","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1038\/s41372-020-0656-7","volume":"40","author":"MW Harer","year":"2020","unstructured":"Harer MW, Charlton JR, Tipple TE, Reidy KJ. 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