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The percentage of 10\u2009mL\/kg transfusions improved from 17.6% to 100%, without increasing major bleeding and repeat transfusion rates. Monthly transfused platelet volumes decreased from 2269\u2009\u00b1\u2009334\u2009mL to 857\u2009\u00b1\u2009181\u2009mL (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), conserving limited platelet resources and saving $2746\u2013$4942 per month in platelets.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study improved our platelet transfusion practices and can facilitate similar transfusion guideline adoption to benefit neonates at other institutions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1038\/s41372-025-02347-5","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T08:52:50Z","timestamp":1752137570000},"page":"1825-1832","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["An improvement project standardizing low prophylactic platelet transfusion dosing for infants"],"prefix":"10.1038","volume":"45","author":[{"given":"Kristen","family":"Coletti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Hershey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Devine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Taft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Schinella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sekinah","family":"Ajiboye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Gibbs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele P.","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1830-9922","authenticated-orcid":false,"given":"Christopher S.","family":"Thom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"key":"2347_CR1","doi-asserted-by":"publisher","first-page":"710","DOI":"10.3109\/08880018.2012.725454","volume":"29","author":"F Bolat","year":"2012","unstructured":"Bolat F, K\u0131l\u0131\u00e7 S\u00c7, Oflaz MB, Gulhan E, Kaya A, Guven AS, et al. 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MPL is an advisory board member for Octapharma, Dova, Principia, Janssen, Sobi, argenx, PDSA, 22qSociety and CdLS Foundation; a consultant for Novartis Dova, Principia, argenx, Rigel, Sobi, Sanofi, and Janssen, and has received research funding from FWGBD, PDSA, NIH, Sysmex, NovarAtis, Principia, Janssen, argenx, Dova, Octapharma, and Sanofi. None of these is related to this project. The other authors have no conflicts of interest to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}