{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:51:07Z","timestamp":1782125467701,"version":"3.54.5"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"DOI":"10.1038\/s41372-026-02747-1","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:22:18Z","timestamp":1782123738000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Timing of echocardiography in the hemodynamic assessment of neonatal hypoxic-ischemic encephalopathy"],"prefix":"10.1038","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4027-5805","authenticated-orcid":false,"given":"Srirupa","family":"Hari Gopal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5103-5834","authenticated-orcid":false,"given":"Philip","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit M.","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"2747_CR1","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.clp.2023.11.007","volume":"51","author":"R Geisinger","year":"2024","unstructured":"Geisinger R, Rios DR, McNamara PJ, Levy PT. Asphyxia, therapeutic hypothermia, and pulmonary hypertension. Clin Perinatol. 2024;51:127\u201349.","journal-title":"Clin Perinatol"},{"key":"2747_CR2","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1164\/rccm.201903-0583OC","volume":"200","author":"RE Giesinger","year":"2019","unstructured":"Giesinger RE, El Shahed AI, Castaldo MP, Breatnach CR, Chau V, Whyte HE, et al. Impaired right ventricular performance is associated with adverse outcome after hypoxic ischemic encephalopathy. Am J Respir Crit Care Med. 2019;200:1294\u2013305.","journal-title":"Am J Respir Crit Care Med"},{"key":"2747_CR3","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1136\/archdischild-2020-321463","volume":"107","author":"RE Giesinger","year":"2022","unstructured":"Giesinger RE, El Shahed AI, Castaldo MP, Bischoff AR, Chau V, Whyte HEA, et al. Neurodevelopmental outcome following hypoxic ischaemic encephalopathy and therapeutic hypothermia is related to right ventricular performance at 24-hour postnatal age. Arch Dis Child Fetal Neonatal Ed. 2022;107:70\u20135.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"2747_CR4","doi-asserted-by":"publisher","unstructured":"Surak A, Schm\u00f6lzer GM, McNamara PJ, Ting JY, Alshareef M, Mohammad K. Hemodynamics in infants with hypoxemic ischemic encephalopathy: pathophysiology and beyond. J Perinatol. 2025 https:\/\/doi.org\/10.1038\/s41372-025-02516-6.","DOI":"10.1038\/s41372-025-02516-6"},{"key":"2747_CR5","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1038\/s41390-020-01205-8","volume":"90","author":"RE Giesinger","year":"2021","unstructured":"Giesinger RE, Levy PT, Ruoss JL, El Dib M, Mohammad K, Wintermark P, et al. Cardiovascular management following hypoxic-ischemic encephalopathy in North America: need for physiologic consideration. Pediatr Res. 2021;90:600\u20137.","journal-title":"Pediatr Res"},{"key":"2747_CR6","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.echo.2023.11.016","volume":"37","author":"PJ McNamara","year":"2024","unstructured":"McNamara PJ, Jain A, El-Khuffash A, Giesinger R, Weisz D, Freud L, et al. Guidelines and recommendations for targeted neonatal echocardiography and cardiac point-of-care ultrasound in the neonatal intensive care unit: an update from the American Society of Echocardiography. J Am Soc Echocardiogr. 2024;37:171\u2013215.","journal-title":"J Am Soc Echocardiogr"},{"key":"2747_CR7","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1038\/s41372-024-01958-8","volume":"44","author":"AM Vasquez","year":"2024","unstructured":"Vasquez AM, Bischoff AR, Giesinger RE, McNamara PJ. Impact of therapeutic hypothermia (TH) on echocardiography indices of pulmonary hemodynamics among neonates with hypoxic ischemic encephalopathy (HIE). J Perinatol. 2024;44:1212\u20135.","journal-title":"J Perinatol"},{"key":"2747_CR8","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/s41390-018-0075-z","volume":"84","author":"PT Levy","year":"2018","unstructured":"Levy PT, Tissot C, Horsberg Eriksen B, Nestaas E, Rogerson S, McNamara PJ, et al. Application of neonatologist performed echocardiography in the assessment and management of neonatal heart failure unrelated to congenital heart disease. Pediatr Res. 2018;84:78\u201388.","journal-title":"Pediatr Res"},{"key":"2747_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2022.105563","volume":"167","author":"F Ovali","year":"2022","unstructured":"Ovali F. Hemodynamic changes and evaluation during hypoxic-ischemic encephalopathy and therapeutic hypothermia. Early Hum Dev. 2022;167:105563.","journal-title":"Early Hum Dev"},{"key":"2747_CR10","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s00431-026-06754-4","volume":"185","author":"S Yu","year":"2026","unstructured":"Yu S, Xiao T, Li B, Zhang Q, Zhang J, Fu J, et al. Hemodynamic changes in neonatal hypoxic-ischemic encephalopathy requiring therapeutic hypothermia. Eur J Pediatr. 2026;185:93.","journal-title":"Eur J Pediatr"},{"key":"2747_CR11","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1159\/000521694","volume":"119","author":"PK Yajamanyam","year":"2022","unstructured":"Yajamanyam PK, Negrine RJS, Rasiah SV, Plana MN, Zamora J, Ewer AK. Left ventricular dysfunction persists in the first week after re-warming following therapeutic hypothermia for hypoxic-ischaemic encephalopathy. Neonatology. 2022;119:510\u20136.","journal-title":"Neonatology"},{"key":"2747_CR12","doi-asserted-by":"crossref","unstructured":"Zanelli SA, Wusthoff CJ, Lucke AM, Kaufman DA. Therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy: clinical report. Pediatrics. 2026,157.","DOI":"10.1542\/peds.2025-073627"},{"key":"2747_CR13","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1055\/a-2632-9833","volume":"42","author":"E Diaz","year":"2025","unstructured":"Diaz E, Lemus R, Ahmed ST, Couch S, Chalak L, Digeronimo R, et al. ECMO use in neonates with hypoxic-ischemic encephalopathy: a state-of-the-art narrative review of feasibility, efficacy, and safety. Am J Perinatol. 2025;42:2104\u201310.","journal-title":"Am J Perinatol"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02747-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02747-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02747-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:22:25Z","timestamp":1782123745000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02747-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,22]]},"references-count":13,"alternative-id":["2747"],"URL":"https:\/\/doi.org\/10.1038\/s41372-026-02747-1","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,22]]},"assertion":[{"value":"12 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 June 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Levy received an honorarium for speaking at the Abbot Structural Heart.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}