{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T15:07:13Z","timestamp":1789744033932,"version":"4.0.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1038\/s41372-026-02855-y","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T07:58:58Z","timestamp":1787644738000},"page":"1740-1746","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hyperbilirubinemia in premature infants &lt;35 weeks\u2019 gestation: A chronologic age format for graphing consensus-based recommendations"],"prefix":"10.1038","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4485-0528","authenticated-orcid":false,"given":"Robert L.","family":"Stavis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0303-6177","authenticated-orcid":false,"given":"Jack D.","family":"Guida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"2855_CR1","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/jp.2012.71","volume":"32","author":"MJ Maisels","year":"2012","unstructured":"Maisels MJ, Watchko JF, Bhutani VK, Stevenson DK. An approach to the management of hyperbilirubinemia in the preterm infant less than 35 weeks of gestation. J Perinatol. 2012;32:660\u20134. https:\/\/doi.org\/10.1038\/jp.2012.71.","journal-title":"J Perinatol"},{"key":"2855_CR2","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.clp.2013.07.007","volume":"40","author":"MB Wallenstein","year":"2013","unstructured":"Wallenstein MB, Bhutani VK. Jaundice and kernicterus in the moderately preterm infant. Clin Perinatol. 2013;40:679\u201388. https:\/\/doi.org\/10.1016\/j.clp.2013.07.007.","journal-title":"Clin Perinatol"},{"key":"2855_CR3","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.clp.2016.01.009","volume":"43","author":"JP Palma","year":"2016","unstructured":"Palma JP, Arain YH. Development of a web-based decision support tool to operationalize and optimize management of hyperbilirubinemia in preterm infants. Clin Perinatol. 2016;43:375\u201383. https:\/\/doi.org\/10.1016\/j.clp.2016.01.009.","journal-title":"Clin Perinatol"},{"key":"2855_CR4","unstructured":"Stanford Medicine Children\u2019s Health. Premie BiliRecs. Available from: https:\/\/pbr.stanfordchildrens.org (Accessed January 3, 2026)."},{"key":"2855_CR5","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1038\/s41372-020-00782-0","volume":"40","author":"Y Arain","year":"2020","unstructured":"Arain Y, Banda JM, Faulkenberry J, Bhutani VK, Palma JP. Clinical decision support tool for phototherapy initiation in preterm infants. J Perinatol. 2020;40:1518\u201323. https:\/\/doi.org\/10.1038\/s41372-020-00782-0.","journal-title":"J Perinatol"},{"key":"2855_CR6","unstructured":"Epic Systems, Verona, WI, USA. Available from: https:\/\/www.epic.com (Accessed January 3, 2026)."},{"key":"2855_CR7","doi-asserted-by":"publisher","first-page":"e2022058859","DOI":"10.1542\/peds.2022-058859","volume":"150","author":"AR Kemper","year":"2022","unstructured":"Kemper AR, Newman TB, Slaughter JL, Maisels MJ, Watchko JF, Downs SM, et al. Clinical practice guideline revision: Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2022;150:e2022058859. https:\/\/doi.org\/10.1542\/peds.2022-058859.","journal-title":"Pediatrics"},{"key":"2855_CR8","unstructured":"Grand Rounds Software, Bryn Mawr, PA, USA. Available from: https:\/\/www.cribnotes.com (Accessed January 3, 2026)."},{"key":"2855_CR9","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.earlhumdev.2011.04.004","volume":"87","author":"DE Van Imhoff","year":"2011","unstructured":"Imhoff DE, Dijk PH, Hulzebos CV. Uniform treatment thresholds for hyperbilirubinemia in preterm infants: background and synopsis of a national guideline. Early Hum Dev. 2011;87:521\u20135. https:\/\/doi.org\/10.1016\/j.earlhumdev.2011.04.004.","journal-title":"Early Hum Dev"},{"key":"2855_CR10","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1111\/j.1651-2227.2010.02104.x","volume":"100","author":"D Bratlid","year":"2011","unstructured":"Bratlid D, Nakstad B, Hansen TWR. National guidelines for treatment of jaundice in the newborn. Acta Paediatr. 2011;100:499\u2013505. https:\/\/doi.org\/10.1111\/j.1651-2227.2010.02104.x.","journal-title":"Acta Paediatr"},{"key":"2855_CR11","unstructured":"Phototherapy and exchange transfusion guidelines for preterm infants <35 weeks gestational age (November 22, 2019). Available from: https:\/\/torontocentreforneonatalhealth.com\/wp-content\/uploads\/2019\/07\/Phototherapy-and-Exchange-Transfusion-Guidelines-for-Preterm-Infants-Less-Than-35-Weeks-Gestation-1.pdf. (Accessed January 3, 2026)."},{"key":"2855_CR12","unstructured":"National Institute for Health and Clinical Excellence. Jaundice in newborn babies under 28 days. Clinical guideline; Reference number: CG98. Available from: https:\/\/www.nice.org.uk\/guidance\/CG98\/resources (see \u201cTreatment threshold graphs\u201d) (Accessed January 3, 2026)."},{"key":"2855_CR13","volume-title":"The Visual Display of Quantitative Information","author":"ER Tufte","year":"2001","unstructured":"Tufte ER The Visual Display of Quantitative Information. 2nd ed. Cheshire, CT: Graphics Press; 2001.","edition":"2nd ed"},{"key":"2855_CR14","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1126\/science.229.4716.828","volume":"229","author":"WS Cleveland","year":"1985","unstructured":"Cleveland WS, McGill R. Graphical perception and graphical methods for analyzing scientific data. Science. 1985;229:828\u201333.","journal-title":"Science"},{"key":"2855_CR15","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1080\/01621459.1988.10478598","volume":"83","author":"WS Cleveland","year":"1988","unstructured":"Cleveland WS, McGill ME, McGill R. The shape parameter of a two-variable graph. J Am Stat. 1988;83:289\u2013300.","journal-title":"J Am Stat"},{"key":"2855_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-025-02534-0","volume":"25","author":"B Nagavci","year":"2025","unstructured":"Nagavci B, G\u00e1sp\u00e1r Z, Lakatos B. Defining expert opinion in clinical guidelines: insights from 98 scientific societies \u2013 a methodological study. BMC Med Res Methodol. 2025;25:87. https:\/\/doi.org\/10.1186\/s12874-025-02534-0.","journal-title":"BMC Med Res Methodol"},{"key":"2855_CR17","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/s41372-025-02484-x","volume":"46","author":"D De Luca","year":"2026","unstructured":"De Luca D, Neri C, Monin V, Bhutani V. Phototherapy exposure variability in extremely preterm neonates due to different treatment protocols and devices: cross-sectional study. J Perinatol. 2026;46:69\u201374. https:\/\/doi.org\/10.1038\/s41372-025-02484-x.","journal-title":"J Perinatol"},{"key":"2855_CR18","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1038\/s41390-024-03191-7","volume":"96","author":"I Kuitunen","year":"2024","unstructured":"Kuitunen I, Nikkil\u00e4 A, Kiviranta P, J\u00e4\u00e4skel\u00e4inen J, Auvinen A. Risk of childhood neoplasms related to neonatal phototherapy \u2013 a systematic review and meta-analysis. Pediatr Res. 2024;96:1131\u201340. https:\/\/doi.org\/10.1038\/s41390-024-03191-7.","journal-title":"Pediatr Res"},{"key":"2855_CR19","doi-asserted-by":"publisher","first-page":"1667636","DOI":"10.3389\/fped.2025.1667636","volume":"13","author":"SJ Freeman","year":"2025","unstructured":"Freeman SJ, Keown-Stoneman CD, Ghobrial M, Jegathesan T, Sgro MD. Neonatal phototherapy and cancer risk: a systematic review and meta-analysis. Front Pediatr. 2025;13:1667636. https:\/\/doi.org\/10.3389\/fped.2025.1667636.","journal-title":"Front Pediatr"},{"key":"2855_CR20","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.1056\/NEJMoa0803024","volume":"359","author":"BH Morris","year":"2008","unstructured":"Morris BH, Oh W, Tyson JE, Stevenson DK, Phelps DL, O\u2019Shea M, et al. Aggressive vs. conservative phototherapy for infants with extremely low birth weight. N Engl J Med. 2008;359:1885\u201396. https:\/\/doi.org\/10.1056\/NEJMoa0803024.","journal-title":"N Engl J Med"},{"key":"2855_CR21","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1038\/jp.2012.64","volume":"32","author":"JE Tyson","year":"2012","unstructured":"Tyson JE, Pedroza C, Langer J, Green C, Morris B, Stevenson D, et al. Does aggressive phototherapy increase mortality while decreasing profound impairment among the smallest and sickest newborns? J Perinatol. 2012;32:677\u201384. https:\/\/doi.org\/10.1038\/jp.2012.64.","journal-title":"J Perinatol"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02855-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02855-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02855-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T14:22:59Z","timestamp":1789741379000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41372-026-02855-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,25]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["2855"],"URL":"https:\/\/doi.org\/10.1038\/s41372-026-02855-y","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-8875195\/v1","asserted-by":"object"}]},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,25]]},"assertion":[{"value":"13 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 August 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Dr. Stavis is the developer and vendor of the Crib Notes neonatal EHR in which the approach described in this article was developed and implemented. The approach described is independent of any specific EHR platform and does not include proprietary logic; sufficient details for independent replication are provided herein. Dr. Guida declares no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"Artificial intelligence had no role in the development of the modified consensus guidelines or the content, analyses, or interpretations described in this paper. After the manuscript and graphics were fully developed, ChatGPT (OpenAI) was used to help improve clarity and refine the style of the paper. The Bilirubin Guidelines tool was initially developed with Microsoft Excel; ChatGPT was used to assist programming the Visual Basic macros in Excel and with translation to the JavaScript application. The authors take full responsibility for this manuscript.","order":2,"name":"Ethics","label":"Use of artificial intelligence","group":{"name":"EthicsHeading","label":"Ethics"}}]}}