{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:37:53Z","timestamp":1787002673658,"version":"build-2736575974"},"reference-count":72,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":375,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000245","name":"Michael Smith Foundation for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000245","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009710","name":"Myocarditis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012453","name":"Providence Health Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012453","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Providence Health Care Research Institute"}],"content-domain":{"domain":["li.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Laboratory Investigation"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1038\/s41374-021-00669-4","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T12:22:42Z","timestamp":1633350162000},"page":"14-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Advanced detection strategies for cardiotropic virus infection in a cohort study of heart failure patients"],"prefix":"10.1016","volume":"102","author":[{"given":"Paul J.","family":"Hanson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Liu-Fei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor A.","family":"Minato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Al Rohet","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpreet","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria A.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coco","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjetil","family":"Ask","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy A.","family":"Hirota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce M.","family":"McManus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/s41374-021-00669-4_bib1","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics-2020 update: a report from the American Heart Association","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib2","doi-asserted-by":"crossref","first-page":"216","DOI":"10.24095\/hpcdp.39.6\/7.02","article-title":"Original quantitative research Trends in chronic disease incidence rates from the Canadian Chronic Disease Surveillance System","volume":"39","author":"Hamm","year":"2019","journal-title":"Health Promot. Chronic Dis. Prev. Can."},{"key":"10.1038\/s41374-021-00669-4_bib3","first-page":"382","article-title":"Epidemiology and diagnosis of viral myocarditis","volume":"54","author":"Lv","year":"2013","journal-title":"Hellenic J. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib4","first-page":"7","article-title":"The epidemiology of viral heart disease","volume":"88","author":"Friman","year":"1993","journal-title":"Scand. J. Infect. Dis. Suppl."},{"key":"10.1038\/s41374-021-00669-4_bib5","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-14-147","article-title":"Measuring underreporting and under-ascertainment in infectious disease datasets: a comparison of methods","volume":"14","author":"Gibbons","year":"2014","journal-title":"BMC Public Health"},{"key":"10.1038\/s41374-021-00669-4_bib6","first-page":"577","article-title":"Hepatitis E in Germany\u2014an under-reported infectious disease","volume":"111","author":"Pischke","year":"2014","journal-title":"Dtsch. Arztebl."},{"key":"10.1038\/s41374-021-00669-4_bib7","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1161\/CIRCRESAHA.115.306573","article-title":"McManus B. Myocarditis","volume":"118","author":"Fung","year":"2016","journal-title":"Circ. Res."},{"key":"10.1038\/s41374-021-00669-4_bib8","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0735-1097(89)90465-8","article-title":"Insensitivity of right ventricular endomyocardial biopsy in the diagnosis of myocarditis","volume":"14","author":"Chow","year":"1989","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib9","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0025-6196(11)60670-8","article-title":"Diagnosis and treatment of viral myocarditis","volume":"84","author":"Schultz","year":"2009","journal-title":"Mayo Clin. Proc."},{"key":"10.1038\/s41374-021-00669-4_bib10","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1007\/s10156-012-0499-z","article-title":"A national survey on myocarditis associated with influenza H1N1pdm2009 in the pandemic and postpandemic season in Japan","volume":"19","author":"Ukimura","year":"2013","journal-title":"J. Infect. Chemother."},{"key":"10.1038\/s41374-021-00669-4_bib11","doi-asserted-by":"crossref","first-page":"78","DOI":"10.5144\/0256-4947.2016.78","article-title":"Acute myocarditis associated with novel Middle east respiratory syndrome coronavirus","volume":"36","author":"Alhogbani","year":"2016","journal-title":"Ann. Saudi. Med."},{"key":"10.1038\/s41374-021-00669-4_bib12","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1093\/eurheartj\/ehaa231","article-title":"Coronaviruses and the cardiovascular system: acute and long-term implications","volume":"41","author":"Xiong","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1038\/s41374-021-00669-4_bib13","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1093\/cvr\/cvq407","article-title":"What we learned from pandemic H1N1 influenza A","volume":"89","author":"Yamauchi-Takihara","year":"2010","journal-title":"Cardiovasc. Res."},{"key":"10.1038\/s41374-021-00669-4_bib14","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.3201\/eid1811.120090","article-title":"Coxsackievirus B3, Shandong Province, China, 1990-2010","volume":"18","author":"Tao","year":"2012","journal-title":"Emerg. Infect. Dis."},{"key":"10.1038\/s41374-021-00669-4_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2020.102434","article-title":"The deadly coronaviruses: the 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China","volume":"109","author":"Yang","year":"2020","journal-title":"J. Autoimmun."},{"key":"10.1038\/s41374-021-00669-4_bib16","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1080\/13550280591002531","article-title":"Enteroviruses as agents of emerging infectious diseases","volume":"11","author":"Palacios","year":"2005","journal-title":"J. Neurovirol."},{"key":"10.1038\/s41374-021-00669-4_bib17","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0735-1097(03)00648-X","article-title":"Detection of viruses in myocardial tissues by polymerase chain reaction. evidence of adenovirus as a common cause of myocarditis in children and adults","volume":"42","author":"Bowles","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib18","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/ejhf.665","article-title":"Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature","volume":"18","author":"Verdonschot","year":"2016","journal-title":"Eur. J. Heart Fail."},{"key":"10.1038\/s41374-021-00669-4_bib19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.cardfail.2005.11.004","article-title":"Myocarditis and heart failure associated with hepatitis C virus infection","volume":"12","author":"Matsumori","year":"2006","journal-title":"J. Card. Fail."},{"key":"10.1038\/s41374-021-00669-4_bib20","article-title":"Acute viral hepatitis e is associated with the development of myocarditis","volume":"2015","author":"Premkumar","year":"2015","journal-title":"Case Rep. Hepatol."},{"key":"10.1038\/s41374-021-00669-4_bib21","first-page":"897","article-title":"Myocarditis as the initial presentation of Epstein-Barr virus infection in a 17-year-old male patient","volume":"65","author":"Ace","year":"2019","journal-title":"Can. Fam. Phys."},{"key":"10.1038\/s41374-021-00669-4_bib22","first-page":"219","article-title":"Fatal Influenza B Myocarditis in a 34-Year-Old Female","volume":"2","author":"Dickey","year":"2018","journal-title":"Clin. Pract. Cases Emerg. Med."},{"key":"10.1038\/s41374-021-00669-4_bib23","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2169\/internalmedicine.53.1117","article-title":"Repetitive fulminant influenza myocarditis requiring the use of circulatory assist devices","volume":"53","author":"Yoshimizu","year":"2014","journal-title":"Intern. Med."},{"key":"10.1038\/s41374-021-00669-4_bib24","article-title":"Myocarditis associated with influenza A H1N1pdm2009","volume":"2012","author":"Ukimura","year":"2012","journal-title":"Influenza Res. Treat."},{"key":"10.1038\/s41374-021-00669-4_bib25","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1161\/01.CIR.0000155616.07901.35","article-title":"High prevalence of viral genomes and multiple viral infections in the myocardium of adults with \u201cidiopathic\u201d left ventricular dysfunction","volume":"111","author":"Kuhl","year":"2005","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.carpath.2005.10.004","article-title":"Arrhythmogenic right ventricular cardiomyopathy\/dysplasia: is there a role for viruses?","volume":"15","author":"Calabrese","year":"2006","journal-title":"Cardiovasc. Pathol."},{"key":"10.1038\/s41374-021-00669-4_bib27","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/S0735-1097(02)01688-1","article-title":"The detection of cardiotropic viruses in the myocardium of patients with arrhythmogenic right ventricular dysplasia\/cardiomyopathy","volume":"39","author":"Bowles","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib28","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/S2468-1253(19)30227-4","article-title":"Global burden of atherosclerotic cardiovascular disease in people with hepatitis C virus infection: a systematic review, meta-analysis, and modelling study","volume":"4","author":"Lee","year":"2019","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"10.1038\/s41374-021-00669-4_bib29","doi-asserted-by":"crossref","first-page":"343","DOI":"10.14218\/JCTH.2017.00021","article-title":"Risk of cardiovascular disease due to chronic hepatitis C infection: a review","volume":"5","author":"Babiker","year":"2017","journal-title":"J. Clin. Transl. Hepatol."},{"key":"10.1038\/s41374-021-00669-4_bib30","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1016\/j.amjcard.2019.01.046","article-title":"Relation of concomitant heart failure to outcomes in patients hospitalized with influenza","volume":"123","author":"Panhwar","year":"2019","journal-title":"Am. J. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib31","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1001\/jamacardio.2019.0549","article-title":"Association of influenza-like illness activity with hospitalizations for heart failure: the atherosclerosis risk in communities study","volume":"4","author":"Kytomaa","year":"2019","journal-title":"JAMA Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib32","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1126\/science.abe2813","article-title":"COVID-19 can affect the heart","volume":"370","author":"Topol","year":"2020","journal-title":"Science"},{"key":"10.1038\/s41374-021-00669-4_bib33","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1001\/jamacardio.2020.1096","article-title":"Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19)","volume":"5","author":"Inciardi","year":"2020","journal-title":"JAMA Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib34","article-title":"Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study","volume":"368","author":"Chen","year":"2020","journal-title":"BMJ"},{"key":"10.1038\/s41374-021-00669-4_bib35","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1001\/jamacardio.2020.1286","article-title":"Potential effects of coronaviruses on the cardiovascular system: a review","volume":"5","author":"Madjid","year":"2020","journal-title":"JAMA Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib36","doi-asserted-by":"crossref","first-page":"546","DOI":"10.5114\/aoms.2011.24118","article-title":"Cardiac sarcoidosis: a comprehensive review","volume":"7","author":"Sekhri","year":"2011","journal-title":"Arch. Med. Sci."},{"key":"10.1038\/s41374-021-00669-4_bib37","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1002\/ejhf.1319","article-title":"Management and outcomes of cardiac sarcoidosis: a 20\u2010year experience in two tertiary care centres","volume":"20","author":"Fussner","year":"2018","journal-title":"Eur. J. Heart Fail."},{"key":"10.1038\/s41374-021-00669-4_bib38","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.120.007103","article-title":"Virome sequencing in patients with myocarditis","volume":"13","author":"Heidecker","year":"2020","journal-title":"Circ. Heart Fail."},{"key":"10.1038\/s41374-021-00669-4_bib39","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000008846","article-title":"Severe infections in sarcoidosis: incidence, predictors and long-term outcome in a cohort of 585 patients","volume":"96","author":"Dur\u00e9ault","year":"2017","journal-title":"Medicine"},{"key":"10.1038\/s41374-021-00669-4_bib40","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1089\/vim.2017.0009","article-title":"Virus-associated extrahepatic manifestations in lung and heart and antiviral therapy-related cardiopulmonary toxicity","volume":"30","author":"Hepatitis","year":"2017","journal-title":"Viral. Immunol."},{"key":"10.1038\/s41374-021-00669-4_bib41","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s00380-003-0705-0","article-title":"Prevalence of hepatitis C virus infection among patients with hypertrophic cardiomyopathy","volume":"18","author":"Teragaki","year":"2003","journal-title":"Heart Vessels"},{"key":"10.1038\/s41374-021-00669-4_bib42","first-page":"180","article-title":"Acute viral myocarditis: current concepts in diagnosis and treatment","volume":"15","author":"Shauer","year":"2013","journal-title":"ISR Med. Assoc. J."},{"key":"10.1038\/s41374-021-00669-4_bib43","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1136\/heart.84.1.106","article-title":"Diagnosis and management of dilated cardiomyopathy","volume":"84","author":"Elliott","year":"2000","journal-title":"Heart"},{"key":"10.1038\/s41374-021-00669-4_bib44","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0025-6196(11)60670-8","article-title":"Diagnosis and treatment of viral myocarditis","volume":"84","author":"Schultz","year":"2009","journal-title":"Mayo Clin. Proc."},{"key":"10.1038\/s41374-021-00669-4_bib45","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1586\/14737159.9.2.187","article-title":"Reliability of real-time reverse-transcription PCR in clinical diagnostics: gold standard or substandard?","volume":"9","author":"Murphy","year":"2009","journal-title":"Expert. Rev. Mol. Diagn."},{"key":"10.1038\/s41374-021-00669-4_bib46","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/B978-0-12-420219-1.00009-4","article-title":"Myocarditis","volume":"4","author":"Seidman","year":"2016","journal-title":"Cardiovasc. Pathol."},{"key":"10.1038\/s41374-021-00669-4_bib47","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3390\/v11060566","article-title":"Systematic review of PCR proof of parvovirus B19 genomes in endomyocardial biopsies of patients presenting with myocarditis or dilated cardiomyopathy","volume":"11","author":"Rigopoulos","year":"2019","journal-title":"Viruses"},{"key":"10.1038\/s41374-021-00669-4_bib48","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-020-09049-x","article-title":"Epidemiology of Epstein-Barr virus infection and infectious mononucleosis in the United Kingdom","volume":"20","author":"Kuri","year":"2020","journal-title":"BMC Public Health"},{"key":"10.1038\/s41374-021-00669-4_bib49","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1161\/CIRCULATIONAHA.113.001372","article-title":"Diagnosis and treatment of myocarditis in children in the current era","volume":"129","author":"Canter","year":"2014","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/834e21b0-6acb-40ae-8735-f7ad120c989a","article-title":"Evidence for the role of Epstein Barr Virus infections in the pathogenesis of acute coronary events","volume":"8","author":"Binkley","year":"2013","journal-title":"PLoS One"},{"key":"10.1038\/s41374-021-00669-4_bib51","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.hrtlng.2009.12.012","article-title":"A rare case of Epstein-Barr virus-induced dilated cardiomyopathy","volume":"40","author":"Mutlu","year":"2011","journal-title":"Heart Lung"},{"key":"10.1038\/s41374-021-00669-4_bib52","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/ejhf.665","article-title":"Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature","volume":"18","author":"Verdonschot","year":"2016","journal-title":"Eur. J. Heart Fail."},{"key":"10.1038\/s41374-021-00669-4_bib53","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1161\/CIRCULATIONAHA.108.766022","article-title":"Viral myocarditis: from the perspective of the virus","volume":"119","author":"Yajima","year":"2009","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib54","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.acvd.2009.04.010","article-title":"Viral causes of human myocarditis","volume":"102","author":"Andr\u00e9oletti","year":"2009","journal-title":"Arch Cardiovasc. Dis."},{"key":"10.1038\/s41374-021-00669-4_bib55","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1146\/annurev.pathmechdis.3.121806.151534","article-title":"Molecular biology and pathogenesis of viral myocarditis","volume":"3","author":"Esfandiarei","year":"2008","journal-title":"Annu. Rev. Pathol. Mech. Dis."},{"key":"10.1038\/s41374-021-00669-4_bib56","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1161\/01.CIR.0000124881.00415.59","article-title":"Parvovirus B19 genome in endomyocardial biopsy specimen","volume":"109","author":"Pankuweit","year":"2004","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib57","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1161\/01.RES.0000156077.54903.67","article-title":"Hepatitis C virus infection and cardiomyopathies","volume":"96","author":"Matsumori","year":"2005","journal-title":"Circ. Res."},{"key":"10.1038\/s41374-021-00669-4_bib58","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1161\/01.CIR.0000118493.13323.81","article-title":"Cardiovascular magnetic resonance assessment of human myocarditis: a comparison to histology and molecular pathology","volume":"109","author":"Mahrholdt","year":"2004","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib59","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1161\/CIRCULATIONAHA.110.960054","article-title":"Regulating viral myocarditis: allografted regulatory T cells decrease immune infiltration and viral load","volume":"121","author":"Marchant","year":"2010","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib60","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/eurheartj\/12.suppl_D.18","article-title":"Progress and challenges in the pathological diagnosis of myocarditis","volume":"12","author":"McManus","year":"1991","journal-title":"Eur. Heart J."},{"key":"10.1038\/s41374-021-00669-4_bib61","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1056\/NEJM200105173442002","article-title":"Association of viral genome with graft loss in children after cardiac transplantation","volume":"344","author":"Shirali","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1038\/s41374-021-00669-4_bib62","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.healun.2010.03.003","article-title":"Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients","volume":"29","author":"Breinholt","year":"2010","journal-title":"J. Heart Lung Transplant."},{"key":"10.1038\/s41374-021-00669-4_bib63","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1161\/CIR.0000000000000093","article-title":"Antibody-mediated rejection in cardiac transplantation: emerging knowledge in diagnosis and management","volume":"131","author":"Colvin","year":"2015","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib64","first-page":"1034","article-title":"Corticosteroid therapy for cardiac sarcoidosis: a systematic review","volume":"29","author":"Sadek","year":"2013","journal-title":"Can. J. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib65","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1161\/CIRCULATIONAHA.114.011522","article-title":"Cardiac sarcoidosis: epidemiology, characteristics, and outcome over 25 years in a nationwide study","volume":"131","author":"Kandolin","year":"2015","journal-title":"Circulation"},{"key":"10.1038\/s41374-021-00669-4_bib66","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/S0002-9149(02)02368-8","article-title":"Heart transplantation for undiagnosed cardiac sarcoidosis","volume":"89","author":"Donsky","year":"2002","journal-title":"Am. J. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib67","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jacc.2016.03.605","article-title":"Cardiac sarcoidosis","volume":"68","author":"Birnie","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1038\/s41374-021-00669-4_bib68","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.carpath.2012.02.002","article-title":"Parvovirus B19 is a bystander in adult myocarditis","volume":"21","author":"Koepsell","year":"2012","journal-title":"Cardiovasc. Pathol."},{"key":"10.1038\/s41374-021-00669-4_bib69","article-title":"Incidence of and factors associated with false positives in laboratory diagnosis of norovirus infection by amplification of the RNA-dependent RNA polymerase gene","volume":"9","author":"Lin","year":"2014","journal-title":"PLoS One"},{"key":"10.1038\/s41374-021-00669-4_bib70","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s10741-012-9357-4","article-title":"Viral myocarditis: from experimental models to molecular diagnosis in patients","volume":"18","author":"Pankuweit","year":"2013","journal-title":"Heart Fail. Rev."},{"key":"10.1038\/s41374-021-00669-4_bib71","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s10741-012-9355-6","article-title":"Classification and histological, immunohistochemical, and molecular diagnosis of inflammatory myocardial disease","volume":"18","author":"Basso","year":"2013","journal-title":"Heart Fail. Rev."},{"key":"10.1038\/s41374-021-00669-4_bib72","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.healun.2003.08.026","article-title":"Fatal disseminated adenoviral infection in an adult heart transplant patient","volume":"23","author":"Ivan","year":"2004","journal-title":"J. Heart Lung Transplant."}],"container-title":["Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41374-021-00669-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41374-021-00669-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722001027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722001027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41374-021-00669-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:25:38Z","timestamp":1758396338000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0023683722001027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S0023683722001027"],"URL":"https:\/\/doi.org\/10.1038\/s41374-021-00669-4","relation":{},"ISSN":["0023-6837"],"issn-type":[{"value":"0023-6837","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advanced detection strategies for cardiotropic virus infection in a cohort study of heart failure patients","name":"articletitle","label":"Article Title"},{"value":"Laboratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/s41374-021-00669-4","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}