{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:47:33Z","timestamp":1780606053895,"version":"3.54.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Leukemia"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1038\/s41375-024-02488-0","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T23:58:46Z","timestamp":1733961526000},"page":"508-511","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Growth retardation and adult height in pediatric patients with chronic-phase chronic myeloid leukemia treated with tyrosine kinase inhibitors"],"prefix":"10.1038","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3432-8832","authenticated-orcid":false,"given":"Haruko","family":"Shima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikako","family":"Tono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Tanizawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8232-0912","authenticated-orcid":false,"given":"Akihiro","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Yuza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuko","family":"Hamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8801-0021","authenticated-orcid":false,"given":"Hideki","family":"Muramatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3866-3582","authenticated-orcid":false,"given":"Shoji","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4923-680X","authenticated-orcid":false,"given":"Masaru","family":"Imamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3723-8445","authenticated-orcid":false,"given":"Akiko M.","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souichi","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiichi","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5168-3222","authenticated-orcid":false,"given":"Hiroyuki","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"2488_CR1","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1111\/bjh.19251","volume":"204","author":"N Roy Moulik","year":"2024","unstructured":"Roy Moulik N, Keerthivasagam S, Pandey A, Agiwale J, Hegde K, Chatterjee G, et al. Treatment and follow-up of children with chronic myeloid leukaemia in chronic phase (CML-CP) in the tyrosine kinase inhibitor (TKI) era-Two decades of experience from the Tata Memorial Hospital paediatric CML (pCML) cohort. Br J Haematol. 2024;204:1249\u201361.","journal-title":"Br J Haematol."},{"key":"2488_CR2","doi-asserted-by":"publisher","first-page":"2374","DOI":"10.1182\/blood.2018882233","volume":"133","author":"N Hijiya","year":"2019","unstructured":"Hijiya N, Suttorp M. How I treat chronic myeloid leukemia in children and adolescents. Blood. 2019;133:2374\u201384.","journal-title":"Blood."},{"key":"2488_CR3","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.jpeds.2011.03.046","volume":"159","author":"H Shima","year":"2011","unstructured":"Shima H, Tokuyama M, Tanizawa A, Tono C, Hamamoto K, Muramatsu H, et al. Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia. J Pediatr. 2011;159:676\u201381.","journal-title":"J Pediatr."},{"key":"2488_CR4","doi-asserted-by":"publisher","first-page":"2925","DOI":"10.1182\/bloodadvances.2020003759","volume":"5","author":"N Hijiya","year":"2021","unstructured":"Hijiya N, Maschan A, Rizzari C, Shimada H, Dufour C, Goto H, et al. A phase 2 study of nilotinib in pediatric patients with CML: long-term update on growth retardation and safety. Blood Adv. 2021;5:2925\u201334.","journal-title":"Blood Adv."},{"key":"2488_CR5","volume":"38","author":"J Cai","year":"2023","unstructured":"Cai J, Liu H, Chen Y, Yu J, Gao J, Jiang H, et al. Effect of the tyrosine kinase inhibitors on the growth in children with Philadelphia chromosome-positive acute lymphoblastic leukemia: a case-control study. Lancet Reg Health West Pac. 2023;38:100818.","journal-title":"Lancet Reg Health West Pac."},{"key":"2488_CR6","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1297\/cpe.25.71","volume":"25","author":"T Isojima","year":"2016","unstructured":"Isojima T, Kato N, Ito Y, Kanzaki S, Murata M. Growth standard charts for Japanese children with mean and standard deviation (SD) values based on the year 2000 national survey. Clin Pediatr Endocrinol. 2016;25:71\u201376.","journal-title":"Clin Pediatr Endocrinol."},{"key":"2488_CR7","doi-asserted-by":"crossref","unstructured":"Largo RH, Gasser T, Prader A, Stuetzle W, Huber PJ. Analysis of the adolescent growth spurt using smoothing spline functions. Ann Hum Biol. 1978;5:421\u201334.","DOI":"10.1080\/03014467800003071"},{"key":"2488_CR8","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1297\/cpe.16.85","volume":"16","author":"T Ogata","year":"2007","unstructured":"Ogata T, Tanaka T, Kagami M. Target height and target range for Japanese children: Revisited. Clin Pediatr Endocrinol. 2007;16:85\u201387.","journal-title":"Clin Pediatr Endocrinol."},{"key":"2488_CR9","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/bmt.2012.244","volume":"48","author":"Y Kanda","year":"2013","unstructured":"Kanda Y. Investigation of the freely-available easy-to-use software \u201cEZR\u201d (Easy R) for medical statistics. Bone Marrow Transplant. 2013;48:452\u20138.","journal-title":"Bone Marrow Transplant."},{"key":"2488_CR10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-16996-w","volume":"7","author":"JO Sanders","year":"2017","unstructured":"Sanders JO, Qiu X, Lu X, Duren DL, Liu RW, Dang D, et al. The uniform pattern of growth and skeletal maturation during the human adolescent growth spurt. Sci Rep. 2017;7:16705.","journal-title":"Sci Rep."},{"key":"2488_CR11","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1097\/MPH.0000000000002660","volume":"45","author":"P Gupta","year":"2023","unstructured":"Gupta P, Banothu KK, Haldar P, Gupta AK, Meena JP. Effect of imatinib mesylate on growth in pediatric chronic myeloid leukemia: A systematic review and meta-analysis. J Pediatr Hematol Oncol. 2023;45:227\u201334.","journal-title":"J Pediatr Hematol Oncol."},{"key":"2488_CR12","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1080\/08880018.2019.1610119","volume":"36","author":"D Boddu","year":"2019","unstructured":"Boddu D, Thankamony P, Guruprasad CS, Nair M, Rajeswari B, Seetharam S. Effect of imatinib on growth in children with chronic myeloid leukemia. Pediatr Hematol Oncol. 2019;36:189\u201397.","journal-title":"Pediatr Hematol Oncol."}],"container-title":["Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41375-024-02488-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41375-024-02488-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41375-024-02488-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T10:55:08Z","timestamp":1738666508000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41375-024-02488-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,12]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["2488"],"URL":"https:\/\/doi.org\/10.1038\/s41375-024-02488-0","relation":{},"ISSN":["0887-6924","1476-5551"],"issn-type":[{"value":"0887-6924","type":"print"},{"value":"1476-5551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,12]]},"assertion":[{"value":"11 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"HG received lecture fees from Novartis. All other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}