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The animal experiments in this study have been approved by our Animal Ethics Committee of PRBB and are conducted in accordance with the regulation from the \u201cDepartament de Medi Ambient i Habitatge de la Generalitat de Catalunya\u201d with the protocol number 10655; Ethics Committee on Animal Experimentation (CEEA): ABS-19-0045-P4. Healthy donors mobilized peripheral blood CD34\n                      +\n                      cells were obtained with written informed consent and approval of the Institutional Review Board (IRB) of Fred Hutchinson Cancer Research Center with the approval number #985.03. Cord blood units from healthy newborns were obtained from the Blood Tissue Bank following the institutional guidelines approved by the local IRB with the approval number 206-173-1. All patients or their guardians signed informed consents for sample collection in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}