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BGN reports consultancies\/talks for AstraZeneca, Sanofi, Ionis, Amgen, Amarin, Novartis, Novo Nordisk, Esperion, Lilly, Arrowhead, Marea, and Merck. KFK reports research grants from\n                      \n                      and wife Chastine McKinney M\u00f8ller Foundation, Research Council of Rigshospitalet, The University of Copenhagen, The Danish Heart Foundation, The Danish Agency for Science, Technology and Innovation by The Danish Council for Strategic Research, Novo Nordisk Foundation, Sygeforsikringen \u201cdanmark\u201d, Canon Medical Corporation, GE HealthCare and Novo Nordisk A\/S. PES reports consulting fees from Novo Nordisk and GlaxoSmithKline. AG reports consultancy or advisory roles with AbbVie, Agios, Disc Medicine, Novo Nordisk, Pharmacosmos, Sanofi, and Vertex Pharmaceuticals, and research support from Agios, Bristol Myers Squibb, Novo Nordisk, and Sanofi. JH has received research funding, payment for consultancy, and a conference travel grant from Sanofi, and payment for consultancy from Disc Medicine and AbbVie. The remaining authors declare no competing financial interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"All methods were performed in accordance with the relevant guidelines and regulations. The study was approved by Danish ethical committees (H-KF-01-144\/01), and all participants gave written informed consent.","order":2,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Ethics"}}]}}