{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T01:40:22Z","timestamp":1774662022444,"version":"3.50.1"},"reference-count":45,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":709,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute"},{"name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute"},{"name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute"},{"name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute"},{"name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute"},{"name":"U.S. Department of Health & Human Services | NIH | National Cancer Institute"},{"name":"The Society of Memorial Sloan Kettering Research Grant"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1038\/s41379-020-00667-9","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T11:04:49Z","timestamp":1599044689000},"page":"445-456","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Adverse histology, homozygous loss of CDKN2A\/B, and complex genomic alterations in locally advanced\/metastatic renal mucinous tubular and spindle cell carcinoma"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6371-5930","authenticated-orcid":false,"given":"Chen","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Cimera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Aryeequaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gowtham","family":"Jayakumaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy","family":"Sarungbam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2938-6627","authenticated-orcid":false,"given":"Hikmat A.","family":"Al-Ahmadie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuradha","family":"Gopalan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Joseph","family":"Sirintrapun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samson W.","family":"Fine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satish K.","family":"Tickoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan I.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor E.","family":"Reuter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5207-3648","authenticated-orcid":false,"given":"Ying-Bei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/s41379-020-00667-9_bib1","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.eururo.2005.11.035","article-title":"2004 WHO classification of the renal tumors of the adults","volume":"49","author":"Lopez-Beltran","year":"2006","journal-title":"Eur Urol"},{"key":"10.1038\/s41379-020-00667-9_bib2","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1097\/PAS.0b013e318299f2d1","article-title":"The International Society of Urological Pathology (ISUP) vancouver classification of renal neoplasia","volume":"37","author":"Srigley","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib3","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0090-4295(97)00335-X","article-title":"Low-grade collecting duct carcinoma of the kidney: report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin","volume":"50","author":"MacLennan","year":"1997","journal-title":"Urology"},{"key":"10.1038\/s41379-020-00667-9_bib4","first-page":"107A","article-title":"Unusual renal cell carcinoma (RCC) with prominent spindle cell change possibly related to the loop of Henle","volume":"12","author":"Srigley","year":"1999","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib5","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1053\/hupa.2001.24320","article-title":"Low-grade myxoid renal epithelial neoplasms with distal nephron differentiation","volume":"32","author":"Parwani","year":"2001","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib6","first-page":"182A","article-title":"Phenotypic, molecular and ultrastructural studies of a novel low grade renal epithelial neoplasm possibly related to the loop of Henle","volume":"15","author":"Srigley","year":"2002","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib7","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1097\/01.MP.0000031709.40712.46","article-title":"Low-grade tubular-mucinous renal neoplasms: morphologic, immunohistochemical, and genetic features","volume":"15","author":"Rakozy","year":"2002","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib8","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1046\/j.1365-2559.2002.01515.x","article-title":"Spindle and cuboidal renal cell carcinoma, a tumour having frequent association with nephrolithiasis: report of 11 cases including a case with hybrid conventional renal cell carcinoma\/spindle and cuboidal renal cell carcinoma components","volume":"41","author":"Hes","year":"2002","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00667-9_bib9","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/modpathol.3800499","article-title":"Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas","volume":"19","author":"Brandal","year":"2006","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib10","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/modpathol.3800565","article-title":"Renal mucinous tubular and spindle carcinoma lacks the gains of chromosomes 7 and 17 and losses of chromosome Y that are prevalent in papillary renal cell carcinoma","volume":"19","author":"Cossu-Rocca","year":"2006","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib11","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1097\/PAS.0000000000001038","article-title":"Distinct genomic copy number alterations distinguish mucinous tubular and spindle cell carcinoma of the kidney from papillary renal cell carcinoma with overlapping histologic features","volume":"42","author":"Ren","year":"2018","journal-title":"Am J Surgical Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib12","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1158\/2159-8290.CD-16-0267","article-title":"Biallelic alteration and dysregulation of the hippo pathway in mucinous tubular and spindle cell carcinoma of the kidney","volume":"6","author":"Mehra","year":"2016","journal-title":"Cancer Disco"},{"key":"10.1038\/s41379-020-00667-9_bib13","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.humpath.2007.10.006","article-title":"Mucinous tubular and spindle cell carcinoma with aggressive histomorphology-a sarcomatoid variant","volume":"39","author":"Pillay","year":"2008","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib14","first-page":"180","article-title":"Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid differentiation","volume":"1","author":"Simon","year":"2008","journal-title":"Int J Clin Exp Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib15","first-page":"1517","article-title":"Mucinous tubular and spindle cell carcinoma with Fuhrman nuclear grade 3: a histological, immunohistochemical, ultrastructural and FISH study","volume":"23","author":"Kuroda","year":"2008","journal-title":"Histol Histopathol"},{"key":"10.1038\/s41379-020-00667-9_bib16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/PAS.0b013e3181829ed5","article-title":"Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change","volume":"33","author":"Dhillon","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib17","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.humpath.2009.03.004","article-title":"Aggressive high-grade mucinous tubular and spindle cell carcinoma","volume":"40","author":"Bulimbasic","year":"2009","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib18","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.anndiagpath.2010.08.003","article-title":"High-grade mucinous tubular and spindle cell carcinoma: comparative genomic hybridization study","volume":"15","author":"Kuroda","year":"2011","journal-title":"Ann Diagn Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib19","doi-asserted-by":"crossref","first-page":"557","DOI":"10.4103\/1319-2442.111066","article-title":"Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid transformation","volume":"24","author":"Arafah","year":"2013","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"10.1038\/s41379-020-00667-9_bib20","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3892\/mco.2017.1400","article-title":"Mucin-poor and aggressive mucinous tubular and spindle cell carcinoma of the kidney: two case reports","volume":"7","author":"Uchida","year":"2017","journal-title":"Mol Clin Oncol"},{"key":"10.1038\/s41379-020-00667-9_bib21","first-page":"976","article-title":"Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: a case report","volume":"7","author":"Sakatani","year":"2017","journal-title":"Mol Clin Oncol"},{"key":"10.1038\/s41379-020-00667-9_bib22","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1111\/his.13298","article-title":"Chromosomal abnormalities of high-grade mucinous tubular and spindle cell carcinoma of the kidney","volume":"71","author":"Sadimin","year":"2017","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00667-9_bib23","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.humpath.2010.07.018","article-title":"Mucinous tubular and spindle cell carcinoma of kidney without sarcomatoid change showing metastases to liver and retroperitoneal lymph node","volume":"42","author":"Ursani","year":"2011","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib24","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.anndiagpath.2011.04.001","article-title":"Metastatic renal mucinous tubular and spindle cell carcinoma. Atypical behavior of a rare, morphologically bland tumor","volume":"16","author":"Thway","year":"2012","journal-title":"Ann Diagn Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib25","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/bju.12992","article-title":"Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney: a detailed study of radiological, pathological and clinical outcomes","volume":"116","author":"Kenney","year":"2015","journal-title":"BJU Int"},{"key":"10.1038\/s41379-020-00667-9_bib26","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/nm.4333","article-title":"Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients","volume":"23","author":"Zehir","year":"2017","journal-title":"Nat Med"},{"key":"10.1038\/s41379-020-00667-9_bib27","doi-asserted-by":"crossref","first-page":"e131","DOI":"10.1093\/nar\/gkw520","article-title":"FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing","volume":"44","author":"Shen","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1038\/s41379-020-00667-9_bib28","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.clgc.2019.04.006","article-title":"Mucinous tubular and spindle-cell carcinoma of the kidney: clinical features, genomic profiles, and treatment outcomes","volume":"17","author":"Ged","year":"2019","journal-title":"Clin Genitourin Cancer"},{"key":"10.1038\/s41379-020-00667-9_bib29","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.anndiagpath.2006.09.005","article-title":"Mucinous tubular and spindle cell carcinoma of kidney is probably a variant of papillary renal cell carcinoma with spindle cell features","volume":"11","author":"Shen","year":"2007","journal-title":"Ann Diagn Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib30","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.anndiagpath.2015.04.004","article-title":"Mucinous spindle and tubular renal cell carcinoma: analysis of chromosomal aberration pattern of low-grade, high-grade, and overlapping morphologic variant with papillary renal cell carcinoma","volume":"19","author":"Peckova","year":"2015","journal-title":"Ann Diagn Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib31","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1038\/s41588-018-0165-1","article-title":"Genome doubling shapes the evolution and prognosis of advanced cancers","volume":"50","author":"Bielski","year":"2018","journal-title":"Nat Genet"},{"key":"10.1038\/s41379-020-00667-9_bib32","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0002-9440(10)63982-X","article-title":"Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors","volume":"158","author":"Hing","year":"2001","journal-title":"Am J Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib33","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.1200\/JCO.2012.48.4923","article-title":"Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load","volume":"31","author":"Neben","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1038\/s41379-020-00667-9_bib34","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJM199601253340404","article-title":"Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma","volume":"334","author":"Caron","year":"1996","journal-title":"N. Engl J Med"},{"key":"10.1038\/s41379-020-00667-9_bib35","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0016-5085(97)70169-0","article-title":"Prognostic value of chromosome 1p allelic loss in colon cancer","volume":"113","author":"Ogunbiyi","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1038\/s41379-020-00667-9_bib36","first-page":"4188","article-title":"Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas","volume":"54","author":"Yeh","year":"1994","journal-title":"Cancer Res"},{"key":"10.1038\/s41379-020-00667-9_bib37","doi-asserted-by":"crossref","first-page":"4741","DOI":"10.1038\/sj.onc.1208641","article-title":"KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers","volume":"24","author":"Corson","year":"2005","journal-title":"Oncogene"},{"key":"10.1038\/s41379-020-00667-9_bib38","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1002\/ijc.23901","article-title":"Clinical implication of recurrent copy number alterations in hepatocellular carcinoma and putative oncogenes in recurrent gains on 1q","volume":"123","author":"Kim","year":"2008","journal-title":"Int J Cancer"},{"key":"10.1038\/s41379-020-00667-9_bib39","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF03401664","article-title":"The CDKN2A (p16) gene and human cancer","volume":"3","author":"Foulkes","year":"1997","journal-title":"Mol Med"},{"key":"10.1038\/s41379-020-00667-9_bib40","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.celrep.2018.03.075","article-title":"The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma","volume":"23","author":"Ricketts","year":"2018","journal-title":"Cell Rep"},{"key":"10.1038\/s41379-020-00667-9_bib41","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.celrep.2016.03.043","article-title":"MTAP deletions incancer create vulnerability to targeting of the MAT2A\/PRMT5\/RIOK1 axis","volume":"15","author":"Marjon","year":"2016","journal-title":"Cell Rep"},{"key":"10.1038\/s41379-020-00667-9_bib42","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1126\/science.aad5214","article-title":"MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells","volume":"351","author":"Kryukov","year":"2016","journal-title":"Science"},{"key":"10.1038\/s41379-020-00667-9_bib43","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1097\/01.pas.0000213271.15221.e3","article-title":"Expanding the histologic spectrum of mucinous tubular and spindle cell carcinoma of the kidney","volume":"30","author":"Fine","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib44","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/01.pas.0000180443.94645.50","article-title":"Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution","volume":"30","author":"Paner","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00667-9_bib45","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1097\/PAS.0000000000001150","article-title":"VSTM2A overexpression is a sensitive and specific biomarker for mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney","volume":"42","author":"Wang","year":"2018","journal-title":"Am J Surg Pathol"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00667-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00667-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222006858?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222006858?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00667-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:40:27Z","timestamp":1760229627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222006858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0893395222006858"],"URL":"https:\/\/doi.org\/10.1038\/s41379-020-00667-9","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adverse histology, homozygous loss of CDKN2A\/B, and complex genomic alterations in locally advanced\/metastatic renal mucinous tubular and spindle cell carcinoma","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/s41379-020-00667-9","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}