{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:44:59Z","timestamp":1782456299993,"version":"3.54.5"},"reference-count":68,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":620,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1038\/s41379-020-00691-9","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T13:02:53Z","timestamp":1601989373000},"page":"961-982","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Refined diagnosis of hydatidiform moles with p57 immunohistochemistry and molecular genotyping: updated analysis of a prospective series of 2217 cases"],"prefix":"10.1016","volume":"34","author":[{"given":"Deyin","family":"Xing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte M.","family":"Ronnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/s41379-020-00691-9_bib1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1146\/annurev-pathol-052016-100237","article-title":"Hydatidiform moles: genetic basis and precision diagnosis","volume":"12","author":"Hui","year":"2017","journal-title":"Annu Rev Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib2","unstructured":"Kurman RJ, Carcangiu ML, Herrington CS, Young RH. WHO classification of tumors of female reproductive organs. Lyon: IARC; 2014."},{"key":"10.1038\/s41379-020-00691-9_bib3","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.5858\/arpa.2018-0226-RA","article-title":"Hydatidiform moles: ancillary techniques to refine diagnosis","volume":"142","author":"Ronnett","year":"2018","journal-title":"Arch Pathol Lab Med"},{"key":"10.1038\/s41379-020-00691-9_bib4","first-page":"902","article-title":"Clinical characteristics of persistent gestational trophoblastic neoplasia after partial hydatidiform molar pregnancy","volume":"51","author":"Feltmate","year":"2006","journal-title":"J Reprod Med"},{"key":"10.1038\/s41379-020-00691-9_bib5","first-page":"764","article-title":"Persistent gestational trophoblastic neoplasia after partial hydatidiform mole incidence and outcome","volume":"51","author":"Hancock","year":"2006","journal-title":"J Reprod Med"},{"key":"10.1038\/s41379-020-00691-9_bib6","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1479-828X.2006.00539.x","article-title":"Persistent trophoblast disease following partial molar pregnancy","volume":"46","author":"Wielsma","year":"2006","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1038\/s41379-020-00691-9_bib7","doi-asserted-by":"crossref","first-page":"e0142545","DOI":"10.1371\/journal.pone.0142545","article-title":"Triploidy\u2014observations in 154 Diandric Cases","volume":"10","author":"Scholz","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1038\/s41379-020-00691-9_bib8","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.ajog.2010.06.073","article-title":"Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole","volume":"203","author":"Lurain","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"10.1038\/s41379-020-00691-9_bib9","first-page":"678","article-title":"Management of gestational trophoblastic diseases: subsequent pregnancy experience","volume":"27","author":"Berkowitz","year":"2000","journal-title":"Semin Oncol"},{"key":"10.1038\/s41379-020-00691-9_bib10","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1046\/j.1471-0528.2003.02388.x","article-title":"Risk of recurrent hydatidiform mole and subsequent pregnancy outcome following complete or partial hydatidiform molar pregnancy","volume":"110","author":"Sebire","year":"2003","journal-title":"BJOG."},{"key":"10.1038\/s41379-020-00691-9_bib11","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10024-002-0079-9","article-title":"Histopathological diagnosis of partial and complete hydatidiform mole in the first trimester of pregnancy","volume":"6","author":"Sebire","year":"2003","journal-title":"Pediatr Dev Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib12","first-page":"1723","article-title":"Updated diagnostic criteria for partial and complete hydatidiform moles in early pregnancy","volume":"23","author":"Sebire","year":"2003","journal-title":"Anticancer Res"},{"key":"10.1038\/s41379-020-00691-9_bib13","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0002-9378(78)90792-5","article-title":"The syndromes of hydatidiform mole. II. Morphologic evolution of the complete and partial mole","volume":"132","author":"Szulman","year":"1978","journal-title":"Am J Obstet Gynecol"},{"key":"10.1038\/s41379-020-00691-9_bib14","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1440-1827.1994.tb02603.x","article-title":"Histopathologic study of partial hydatidiform moles and DNA triploid placentas","volume":"44","author":"Fukunaga","year":"1994","journal-title":"Pathol Int"},{"key":"10.1038\/s41379-020-00691-9_bib15","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00004347-200110000-00001","article-title":"Partial hydatidiform mole: clinicopathological features, differential diagnosis, ploidy and molecular studies, and gold standards for diagnosis","volume":"20","author":"Genest","year":"2001","journal-title":"Int J Gynecol Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib16","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1097\/01.pas.0000157996.23059.c1","article-title":"Interobserver and intraobserver variability in the diagnosis of hydatidiform mole","volume":"29","author":"Fukunaga","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib17","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1136\/jcp.46.7.599","article-title":"Can histopathologists reliably diagnose molar pregnancy?","volume":"46","author":"Howat","year":"1993","journal-title":"J Clin Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib18","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/j.1471-0528.1979.tb10793.x","article-title":"Discrepancies in the histological diagnosis of hydatidiform mole","volume":"86","author":"Javey","year":"1979","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1038\/s41379-020-00691-9_bib19","first-page":"622","article-title":"Inter- and intra-pathologist variability in the diagnosis of gestational trophoblastic neoplasia","volume":"69","author":"Messerli","year":"1987","journal-title":"Obstet Gynecol"},{"key":"10.1038\/s41379-020-00691-9_bib20","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/PAS.0b013e31823b13fe","article-title":"Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis","volume":"36","author":"Vang","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib21","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1097\/PAS.0b013e31825ea736","article-title":"Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis for both recently trained and experienced gynecologic pathologists","volume":"36","author":"Gupta","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib22","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1097\/00000478-200110000-00001","article-title":"Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally imprinted gene product p57KIP2","volume":"25","author":"Castrillon","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/modpathol.2013.143","article-title":"Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping","volume":"27","author":"Banet","year":"2014","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib24","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.humpath.2007.05.010","article-title":"P57KIP2 immunostaining and molecular cytogenetics: combined approach aids in diagnosis of morphologically challenging cases with molar phenotype and in detecting androgenetic cell lines in mosaic\/chimeric conceptions","volume":"39","author":"Hoffner","year":"2008","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib25","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1053\/hupa.2002.129421","article-title":"Immunohistochemical characterization of p57(KIP2) expression in early hydatidiform moles","volume":"33","author":"Fukunaga","year":"2002","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib26","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1097\/PAS.0b013e318191f309","article-title":"Diagnosis and subclassification of hydatidiform moles using p57 immunohistochemistry and molecular genotyping: validation and prospective analysis in routine and consultation practice settings with development of an algorithmic approach","volume":"33","author":"McConnell","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib27","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/PAS.0b013e3181520034","article-title":"Genotypic analysis of hydatidiform mole: an accurate and practical method of diagnosis","volume":"32","author":"Bifulco","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib28","doi-asserted-by":"crossref","first-page":"598","DOI":"10.2353\/jmoldx.2009.090039","article-title":"Molecular genotyping of hydatidiform moles: analytic validation of a multiplex short tandem repeat assay","volume":"11","author":"Murphy","year":"2009","journal-title":"J Mol Diagn"},{"key":"10.1038\/s41379-020-00691-9_bib29","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1097\/PAS.0b013e3181a90e01","article-title":"Complete hydatidiform mole with retained maternal chromosomes 6 and 11","volume":"33","author":"McConnell","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib30","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1097\/PAS.0b013e31822d5cff","article-title":"Diandric triploid hydatidiform mole with loss of maternal chromosome 11","volume":"35","author":"DeScipio","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib31","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1053\/j.semdp.2014.03.004","article-title":"Immunohistochemistry and other ancillary techniques in the diagnosis of gestational trophoblastic diseases","volume":"31","author":"Buza","year":"2014","journal-title":"Semin Diagn Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib32","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/PGP.0000000000000232","article-title":"Invasive complete hydatidiform moles: analysis of a case series with genotyping","volume":"35","author":"Bynum","year":"2016","journal-title":"Int J Gynecol Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib33","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jmoldx.2019.09.006","article-title":"Tetraploid partial hydatidiform moles: molecular genotyping and determination of parental contributions","volume":"22","author":"Bynum","year":"2020","journal-title":"J Mol Diagn"},{"key":"10.1038\/s41379-020-00691-9_bib34","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1097\/PAS.0000000000000937","article-title":"Choriocarcinoma in women: analysis of a case series with genotyping","volume":"41","author":"Savage","year":"2017","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib35","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/PGP.0b013e3182630d8c","article-title":"Characterization of androgenetic\/biparental mosaic\/chimeric conceptions, including those with a molar component: morphology, p57 immnohistochemistry, molecular genotyping, and risk of persistent gestational trophoblastic disease","volume":"32","author":"Lewis","year":"2013","journal-title":"Int J Gynecol Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib36","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1136\/jmg.2005.033571","article-title":"Androgenetic\/biparental mosaicism causes placental mesenchymal dysplasia","volume":"43","author":"Kaiser-Rogers","year":"2006","journal-title":"J Med Genet"},{"key":"10.1038\/s41379-020-00691-9_bib37","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/PAT.0b013e3283559c94","article-title":"The placenta in Beckwith-Wiedemann syndrome: genotype-phenotype associations, excessive extravillous trophoblast and placental mesenchymal dysplasia","volume":"44","author":"Armes","year":"2012","journal-title":"Pathology."},{"key":"10.1038\/s41379-020-00691-9_bib38","first-page":"219","article-title":"Simultaneous detection of imprinted gene expression (p57(KIP2)) and molecular cytogenetics (FICTION) in the evaluation of molar pregnancies","volume":"55","author":"Hoffner","year":"2010","journal-title":"J Reprod Med"},{"key":"10.1038\/s41379-020-00691-9_bib39","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3109\/0284186X.2010.512922","article-title":"Reporting and incidence trends of hydatidiform mole in Sweden 1973-2004","volume":"50","author":"Salehi","year":"2011","journal-title":"Acta Oncol"},{"key":"10.1038\/s41379-020-00691-9_bib40","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/j.1471-0528.1986.tb07957.x","article-title":"Parental age and risk of complete and partial hydatidiform mole","volume":"93","author":"Parazzini","year":"1986","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1038\/s41379-020-00691-9_bib41","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1471-0528.2002.t01-1-01037.x","article-title":"Risk of partial and complete hydatidiform molar pregnancy in relation to maternal age","volume":"109","author":"Sebire","year":"2002","journal-title":"BJOG."},{"key":"10.1038\/s41379-020-00691-9_bib42","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1080\/0284186X.2018.1438653","article-title":"Temporal trends in incidence and outcome of hydatidiform mole: a retrospective cohort study","volume":"57","author":"Joneborg","year":"2018","journal-title":"Acta Oncol"},{"key":"10.1038\/s41379-020-00691-9_bib43","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1097\/IGC.0000000000000754","article-title":"A reappraisal of the incidence of placental hydatidiform mole using selective molecular genotyping","volume":"26","author":"Colgan","year":"2016","journal-title":"Int J Gynecol Cancer"},{"key":"10.1038\/s41379-020-00691-9_bib44","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1038\/s41379-020-0566-4","article-title":"Heterozygous\/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease","volume":"33","author":"Zheng","year":"2020","journal-title":"Mod Pathol."},{"key":"10.1038\/s41379-020-00691-9_bib45","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/s41379-018-0031-9","article-title":"The genetics of recurrent hydatidiform moles: new insights and lessons from a comprehensive analysis of 113 patients","volume":"31","author":"Nguyen","year":"2018","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib46","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s13669-013-0076-1","article-title":"Genetics and epigenetics of recurrent hydatidiform moles: basic science and genetic counselling","volume":"3","author":"Nguyen","year":"2014","journal-title":"Curr Obstet Gynecol Rep"},{"key":"10.1038\/s41379-020-00691-9_bib47","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1093\/molehr\/gat056","article-title":"NLRP7 or KHDC3L genes and the etiology of molar pregnancies and recurrent miscarriage","volume":"19","author":"Andreasen","year":"2013","journal-title":"Mol Hum Reprod"},{"key":"10.1038\/s41379-020-00691-9_bib48","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/ng1740","article-title":"Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans","volume":"38","author":"Murdoch","year":"2006","journal-title":"Nat Genet"},{"key":"10.1038\/s41379-020-00691-9_bib49","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.ajhg.2011.08.002","article-title":"Mutations causing familial biparental hydatidiform mole implicate c6orf221 as a possible regulator of genomic imprinting in the human oocyte","volume":"89","author":"Parry","year":"2011","journal-title":"Am J Hum Genet"},{"key":"10.1038\/s41379-020-00691-9_bib50","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/s41379-019-0266-0","article-title":"Paternal uniparental isodisomy of tyrosine hydroxylase locus at chromosome 11p15.4: spectrum of phenotypical presentations simulating hydatidiform moles","volume":"32","author":"Buza","year":"2019","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib51","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/00008480-199712000-00012","article-title":"Molecular genetics of Beckwith-Wiedemann syndrome","volume":"9","author":"Li","year":"1997","journal-title":"Curr Opin Pediatr"},{"key":"10.1038\/s41379-020-00691-9_bib52","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1097\/PAS.0000000000001466","article-title":"Prevalence of partial hydatidiform mole in products of conception from gestations with fetal triploidy merits reflex genotype testing independent of the morphologic appearance of the chorionic villi","volume":"44","author":"Han","year":"2020","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib53","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1038\/ejhg.2011.93","article-title":"Mosaics and moles","volume":"19","author":"Sunde","year":"2011","journal-title":"Eur J Hum Genet"},{"key":"10.1038\/s41379-020-00691-9_bib54","doi-asserted-by":"crossref","first-page":"370e1","DOI":"10.1016\/j.ajog.2014.03.039","article-title":"Triploid pregnancies: genetic and clinical features of 158 cases","volume":"211","author":"Joergensen","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"10.1038\/s41379-020-00691-9_bib55","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1055\/s-0029-1220794","article-title":"Pregnancy complicated by triploidy: a comparison of the three karyotypes","volume":"26","author":"McWeeney","year":"2009","journal-title":"Am J Perinatol"},{"key":"10.1038\/s41379-020-00691-9_bib56","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/S0046-8177(81)80259-6","article-title":"Human triploidy: association with partial hydatidiform moles and nonmolar conceptuses","volume":"12","author":"Szulman","year":"1981","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib57","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1469-1809.1982.tb00714.x","article-title":"Human triploidy: relationship between parental origin of the additional haploid complement and development of partial hydatidiform mole","volume":"46","author":"Jacobs","year":"1982","journal-title":"Ann Hum Genet"},{"key":"10.1038\/s41379-020-00691-9_bib58","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1086\/302951","article-title":"Parental origin and phenotype of triploidy in spontaneous abortions: predominance of diandry and association with the partial hydatidiform mole","volume":"66","author":"Zaragoza","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1038\/s41379-020-00691-9_bib59","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2353\/jmoldx.2010.090184","article-title":"Abnormal villous morphology associated with triple trisomy of paternal origin","volume":"12","author":"Norris-Kirby","year":"2010","journal-title":"J Mol Diagn"},{"key":"10.1038\/s41379-020-00691-9_bib60","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13000-016-0471-9","article-title":"Abnormal villous morphology mimicking a hydatidiform mole associated with paternal trisomy of chromosomes 3,7,8 and unipaternal disomy of chromosome 11","volume":"11","author":"Sebire","year":"2016","journal-title":"Diagn Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib61","first-page":"762","article-title":"Determinants of villous trophoblastic hyperplasia in spontaneous abortions","volume":"11","author":"Redline","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib62","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1111\/j.0001-6349.2005.00882.x","article-title":"Chromosomal anomalies in first-trimester miscarriages","volume":"84","author":"Ljunger","year":"2005","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1038\/s41379-020-00691-9_bib63","doi-asserted-by":"crossref","first-page":"e18041","DOI":"10.1097\/MD.0000000000018041","article-title":"Chromosomal copy number variations in products of conception from spontaneous abortion by next-generation sequencing technology","volume":"98","author":"Dai","year":"2019","journal-title":"Medicine"},{"key":"10.1038\/s41379-020-00691-9_bib64","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/01.GIM.0000160075.96707.04","article-title":"Incidence and spectrum of chromosome abnormalities in spontaneous abortions: new insights from a 12-year study","volume":"7","author":"Menasha","year":"2005","journal-title":"Genet Med"},{"key":"10.1038\/s41379-020-00691-9_bib65","first-page":"351","article-title":"The gynecologist's role in preventing overdiagnosis of ectopic molar pregnancy: a case report","volume":"58","author":"McCullough","year":"2013","journal-title":"J Reprod Med"},{"key":"10.1038\/s41379-020-00691-9_bib66","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/01.pgp.0000164597.19346.b5","article-title":"Overdiagnosis of complete and partial hydatidiform mole in tubal ectopic pregnancies","volume":"24","author":"Sebire","year":"2005","journal-title":"Int J Gynecol Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib67","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1097\/PGP.0b013e3182a1028b","article-title":"Egg donor pregnancy: a potential pitfall in DNA genotyping diagnosis of hydatidiform moles","volume":"33","author":"Buza","year":"2014","journal-title":"Int J Gynecol Pathol"},{"key":"10.1038\/s41379-020-00691-9_bib68","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/PGP.0000000000000395","article-title":"DNA genotyping of nonmolar donor egg pregnancies with abnormal villous morphology: allele zygosity patterns prevent misinterpretation as complete hydatidiform mole","volume":"37","author":"Joseph","year":"2018","journal-title":"Int J Gynecol Pathol"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00691-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00691-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222006251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222006251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00691-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:38:41Z","timestamp":1760229521000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222006251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":68,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S0893395222006251"],"URL":"https:\/\/doi.org\/10.1038\/s41379-020-00691-9","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Refined diagnosis of hydatidiform moles with p57 immunohistochemistry and molecular genotyping: updated analysis of a prospective series of 2217 cases","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/s41379-020-00691-9","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}