{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:42:33Z","timestamp":1793814153124,"version":"4.6.1"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":740,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1038\/s41379-020-00706-5","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T10:02:35Z","timestamp":1603706555000},"page":"78-93","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"S1","title":["Papillary neoplasms of the breast including upgrade rates and management of intraductal papilloma without atypia diagnosed at core needle biopsy"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4737-8468","authenticated-orcid":false,"given":"Edi","family":"Brogi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Krystel-Whittemore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/s41379-020-00706-5_bib1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1097\/PAS.0000000000001340","article-title":"Papillary lesions of the male breast: a study of 117 cases and brief review of the literature demonstrate a broad clinicopathologic spectrum","volume":"44","author":"Zhong","year":"2020","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib2","first-page":"465","article-title":"p63 expression in benign and malignant breast lesions","volume":"19","author":"Stefanou","year":"2004","journal-title":"Histol Histopathol"},{"key":"10.1038\/s41379-020-00706-5_bib3","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1097\/00000478-200608000-00011","article-title":"Intracystic papillary carcinomas of the breast: a reevaluation using a panel of myoepithelial cell markers","volume":"30","author":"Collins","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib4","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1365-2559.2005.02246.x","article-title":"Breast pathology practice: most common problems in a consultation service","volume":"47","author":"Putti","year":"2005","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00706-5_bib5","doi-asserted-by":"crossref","first-page":"578","DOI":"10.5858\/arpa.2016-0371-OA","article-title":"Characteristics of a breast pathology consultation practice","volume":"141","author":"East","year":"2017","journal-title":"Arch Pathol Lab Med"},{"key":"10.1038\/s41379-020-00706-5_bib6","unstructured":"WHO Classification of Tumours Editorial Board. Breast tumours. Vol 2. 5th ed. Lyon, France: IARC; 2019."},{"key":"10.1038\/s41379-020-00706-5_bib7","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1097\/00000478-200606000-00001","article-title":"An analysis of breast cancer risk in women with single, multiple, and atypical papilloma","volume":"30","author":"Lewis","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib8","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/modpathol.2009.142","article-title":"High prevalence of PIK3CA\/AKT pathway mutations in papillary neoplasms of the breast","volume":"23","author":"Troxell","year":"2010","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ajpath.2015.09.004","article-title":"Mutation profiling of usual ductal hyperplasia of the breast reveals activating mutations predominantly at different levels of the PI3K\/AKT\/mTOR pathway","volume":"186","author":"Jahn","year":"2016","journal-title":"Am J Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib10","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1097\/PAS.0b013e3181aec446","article-title":"Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy","volume":"33","author":"Grin","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib11","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/his.12453","article-title":"Immunohistochemistry in the diagnosis of papillary lesions of the breast","volume":"65","author":"Tse","year":"2014","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00706-5_bib12","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1136\/jcp.2008.063016","article-title":"The role of immunohistochemistry in the differential diagnosis of papillary lesions of the breast","volume":"62","author":"Tse","year":"2009","journal-title":"J Clin Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib13","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1097\/01.MP.0000085027.75201.B5","article-title":"Metaplastic spindle cell breast tumors arising within papillomas, complex sclerosing lesions, and nipple adenomas","volume":"16","author":"Gobbi","year":"2003","journal-title":"Mod Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1365-2559.2007.02893.x","article-title":"Recent developments in the histological diagnosis of spindle cell carcinoma, fibromatosis and phyllodes tumour of the breast","volume":"52","author":"Lee","year":"2008","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00706-5_bib15","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1097\/00000478-200108000-00004","article-title":"Low-grade (fibromatosis-like) spindle cell carcinoma of the breast","volume":"25","author":"Sneige","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib16","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/00000478-199303000-00005","article-title":"Low-grade adenosquamous carcinoma of the breast. A clinocopathologic study of 32 cases with ultrastructural analysis","volume":"17","author":"Van Hoeven","year":"1993","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib17","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1002\/(SICI)1097-0142(19990515)85:10<2170::AID-CNCR11>3.0.CO;2-X","article-title":"Metaplastic breast tumors with a dominant fibromatosis-like phenotype have a high risk of local recurrence","volume":"85","author":"Gobbi","year":"1999","journal-title":"Cancer"},{"key":"10.1038\/s41379-020-00706-5_bib18","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1097\/PAS.0b013e31824e0f90","article-title":"Immunohistochemical staining characteristics of low-grade adenosquamous carcinoma of the breast","volume":"36","author":"Kawaguchi","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib19","doi-asserted-by":"crossref","unstructured":"Nakhlis F, Baker GM, Pilewskie M, Gelman R, Calvillo KZ, Ludwig K, et al. The Incidence of Adjacent Synchronous Invasive Carcinoma and\/or Ductal Carcinoma In Situ in Patients with Intraductal Papilloma without Atypia on Core Biopsy: Results from a Prospective Multi-Institutional Registry (TBCRC 034). Ann Surg Oncol. 2020. https:\/\/doi.org\/10.1245\/s10434-020-09215-w [Epub ahead of print].","DOI":"10.1245\/s10434-020-09215-w"},{"key":"10.1038\/s41379-020-00706-5_bib20","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.ejso.2012.08.019","article-title":"Papillary breast lesions diagnosed by core biopsy require complete excision","volume":"38","author":"Fu","year":"2012","journal-title":"Eur J Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib21","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jamcollsurg.2011.12.005","article-title":"Management of papillary breast lesions diagnosed on core-needle biopsy: clinical pathologic and radiologic analysis of 276 cases with surgical follow-up","volume":"214","author":"Rizzo","year":"2012","journal-title":"J Am Coll Surg"},{"issue":"Suppl 3","key":"10.1038\/s41379-020-00706-5_bib22","doi-asserted-by":"crossref","first-page":"S385","DOI":"10.1245\/s10434-015-4773-z","article-title":"An international multicenter review of the malignancy rate of excised papillomatous breast lesions","volume":"22","author":"Foley","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib23","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1245\/s10434-014-4128-1","article-title":"Papillomas of the breast 15 mm or smaller: 4-year experience in a community-based dedicated breast imaging clinic","volume":"22","author":"Glenn","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib24","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1245\/s10434-010-1403-7","article-title":"Are we overtreating papillomas diagnosed on core needle biopsy?","volume":"18","author":"Cyr","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib25","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/tbj.13200","article-title":"Excision recommended in high-risk patients: revisiting the diagnosis of papilloma on core biopsy in the context of patient risk","volume":"25","author":"Chen","year":"2019","journal-title":"Breast J"},{"key":"10.1038\/s41379-020-00706-5_bib26","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1245\/s10434-011-1617-3","article-title":"Papillary lesions initially diagnosed at ultrasound-guided vacuum-assisted breast biopsy: rate of malignancy based on subsequent surgical excision","volume":"18","author":"Chang","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib27","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1007\/s00330-009-1649-2","article-title":"Risk of carcinoma after subsequent excision of benign papilloma initially diagnosed with an ultrasound (US)-guided 14-gauge core needle biopsy: a prospective observational study","volume":"20","author":"Chang","year":"2010","journal-title":"Eur Radiol"},{"key":"10.1038\/s41379-020-00706-5_bib28","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1309\/AJCPTDQCHIWH4OHM","article-title":"Microcalcification is an important factor in the management of breast intraductal papillomas diagnosed on core biopsy","volume":"138","author":"Li","year":"2012","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib29","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1245\/s10434-012-2846-9","article-title":"Management of benign intraductal solitary papilloma diagnosed on core needle biopsy","volume":"20","author":"Swapp","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib30","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1245\/s10434-014-4091-x","article-title":"Papilloma on core biopsy: excision vs. observation","volume":"22","author":"Nakhlis","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib31","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1002\/cncr.30118","article-title":"Breast intraductal papillomas without atypia in radiologic-pathologic concordant core-needle biopsies: rate of upgrade to carcinoma at excision","volume":"122","author":"Pareja","year":"2016","journal-title":"Cancer"},{"key":"10.1038\/s41379-020-00706-5_bib32","doi-asserted-by":"crossref","first-page":"410","DOI":"10.4048\/jbc.2016.19.4.410","article-title":"Predictive factors for upgrading patients with benign breast papillary lesions using a core needle biopsy","volume":"19","author":"Hong","year":"2016","journal-title":"J Breast Cancer"},{"key":"10.1038\/s41379-020-00706-5_bib33","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1245\/s10434-016-5144-0","article-title":"Asymptomatic benign papilloma without atypia diagnosed at ultrasonography-guided 14-gauge core needle biopsy: which subgroup can be managed by observation?","volume":"23","author":"Kim","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib34","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4048\/jbc.2018.21.1.80","article-title":"Benign intraductal papilloma without atypia on core needle biopsy has a low rate of upgrading to malignancy after excision","volume":"21","author":"Han","year":"2018","journal-title":"J Breast Cancer"},{"key":"10.1038\/s41379-020-00706-5_bib35","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ejso.2017.10.214","article-title":"Management of benign papilloma without atypia diagnosed at ultrasound-guided core needle biopsy: scoring system for predicting malignancy","volume":"44","author":"Ahn","year":"2018","journal-title":"Eur J Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib36","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1245\/s10434-019-07180-7","article-title":"Benign papillary breast mass lesions: favorable outcomes with surgical excision or imaging surveillance","volume":"26","author":"Kuehner","year":"2019","journal-title":"Ann Surg Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib37","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s00428-019-02626-5","article-title":"Benign breast papillary lesions diagnosed on core biopsy: upgrade rate and risk factors associated with malignancy on surgical excision","volume":"475","author":"MacColl","year":"2019","journal-title":"Virchows Arch"},{"key":"10.1038\/s41379-020-00706-5_bib38","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1148\/radiol.2019190096","article-title":"Benign breast papilloma without atypia: outcomes of surgical excision versus US-guided directional vacuum-assisted removal or US follow-up","volume":"293","author":"Choi","year":"2019","journal-title":"Radiology"},{"key":"10.1038\/s41379-020-00706-5_bib39","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1007\/s00268-019-05047-2","article-title":"Treatment and outcome of 341 papillary breast lesions","volume":"43","author":"Chen","year":"2019","journal-title":"World J Surg"},{"key":"10.1038\/s41379-020-00706-5_bib40","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/ans.14827","article-title":"Management of papillary lesions without atypia of the breast diagnosed on needle biopsy","volume":"89","author":"Yu","year":"2019","journal-title":"ANZ J Surg"},{"key":"10.1038\/s41379-020-00706-5_bib41","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.acra.2018.08.014","article-title":"Management of BIRADS 3, 4A, and 4B lesions diagnosed as pure papilloma by ultrasound-guided core needle biopsy: is surgical excision necessary?","volume":"26","author":"Raj","year":"2019","journal-title":"Acad Radiol"},{"key":"10.1038\/s41379-020-00706-5_bib42","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.clinimag.2018.04.021","article-title":"Concordant, non-atypical breast papillomas do not require surgical excision: A 10-year multi-institution study and review of the literature","volume":"51","author":"Grimm","year":"2018","journal-title":"Clin Imaging"},{"key":"10.1038\/s41379-020-00706-5_bib43","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/tbj.13642","article-title":"Benign breast papilloma: Is surgical excision necessary?","volume":"26","author":"Moynihan","year":"2020","journal-title":"Breast J"},{"key":"10.1038\/s41379-020-00706-5_bib44","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.amjsurg.2020.01.040","article-title":"Upgrade rate of intraductal papilloma without atypia on breast core needle biopsy: a clinical, radiological and pathological correlation study","volume":"220","author":"Genco","year":"2020","journal-title":"Am J Surg"},{"key":"10.1038\/s41379-020-00706-5_bib45","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.acra.2010.01.001","article-title":"Is surgical excision of core biopsy proven benign papillomas of the breast necessary?","volume":"17","author":"Bennett","year":"2010","journal-title":"Acad Radiol"},{"key":"10.1038\/s41379-020-00706-5_bib46","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.clinimag.2019.10.009","article-title":"Papilloma diagnosed on core biopsies has a low upgrade rate","volume":"60","author":"Li","year":"2020","journal-title":"Clin Imaging"},{"key":"10.1038\/s41379-020-00706-5_bib47","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.crad.2011.01.008","article-title":"The diagnosis of non-malignant papillary lesions of the breast: comparison of ultrasound-guided automated gun biopsy and vacuum-assisted removal","volume":"66","author":"Kim","year":"2011","journal-title":"Clin Radiol"},{"key":"10.1038\/s41379-020-00706-5_bib48","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/tbj.12073","article-title":"Incidental intraductal papillomas (<2 mm) of the breast diagnosed on needle core biopsy do not need to be excised","volume":"19","author":"Jaffer","year":"2013","journal-title":"Breast J"},{"key":"10.1038\/s41379-020-00706-5_bib49","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.humpath.2013.10.027","article-title":"Non-mass-associated intraductal papillomas: is excision necessary?","volume":"45","author":"Weisman","year":"2014","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib50","unstructured":"American Society of Breast Surgeons. Consensus guideline on concordance assessment of image-guided breast biopsies and management of borderline or high-risk lesions. 2016. https:\/\/www.breastsurgeons.org\/docs\/statements\/Consensus-Guideline-on-Concordance-Assessment-of-Image-Guided-Breast-Biopsies.pdf."},{"key":"10.1038\/s41379-020-00706-5_bib51","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1067\/j.cpradiol.2018.06.004","article-title":"Variability in the management recommendations given for high-risk breast lesions detected on image-guided core needle biopsy at U.S. academic institutions","volume":"48","author":"Falomo","year":"2019","journal-title":"Curr Probl Diagn Radiol"},{"key":"10.1038\/s41379-020-00706-5_bib52","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/his.12477","article-title":"Management of breast papillary lesions diagnosed in ultrasound-guided vacuum-assisted and core needle biopsies","volume":"66","author":"Yamaguchi","year":"2015","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00706-5_bib53","doi-asserted-by":"crossref","unstructured":"Pareja F, Weigelt B, Reis-Filho JS. Problematic breast tumors reassessed in light of novel molecular data. Mod Pathol. 2020. https:\/\/doi.org\/10.1038\/s41379-020-00693-7 [Epub ahead of print].","DOI":"10.1038\/s41379-020-00693-7"},{"key":"10.1038\/s41379-020-00706-5_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-018-04128-5","article-title":"Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas","volume":"9","author":"Geyer","year":"2018","journal-title":"Nat Commun"},{"key":"10.1038\/s41379-020-00706-5_bib55","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1159\/000490416","article-title":"Breast tumours resembling the tall cell variant of thyroid papillary carcinoma: are they part of the papillary carcinoma spectrum or a distinct entity?","volume":"86","author":"Toss","year":"2019","journal-title":"Pathobiology"},{"key":"10.1038\/s41379-020-00706-5_bib56","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.humpath.2016.04.014","article-title":"Frequent PIK3CA-activating mutations in hidradenoma papilliferums","volume":"55","author":"Liau","year":"2016","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib57","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.pathol.2016.09.068","article-title":"Clear cell hidradenoma of the breast with MAML2 gene rearrangement","volume":"49","author":"Hsieh","year":"2017","journal-title":"Pathology"},{"key":"10.1038\/s41379-020-00706-5_bib58","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.5858\/2005-129-1465-EDIBLA","article-title":"Epithelial displacement in breast lesions: a papillary phenomenon","volume":"129","author":"Nagi","year":"2005","journal-title":"Arch Pathol Lab Med"},{"key":"10.1038\/s41379-020-00706-5_bib59","unstructured":"Lakhani SR, Ellis I, Schnitt SJ, Tan PH, Van de Vijver MJ, editors. WHO Classification of Tumours of the Breast. 4th edition. Geneva, Switzerland: WHO Press; 2012."},{"key":"10.1038\/s41379-020-00706-5_bib60","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/0046-8177(94)90250-X","article-title":"Intraductal (intracystic) papillary carcinoma of the breast and its variants: a clinicopathological study of 77 cases","volume":"25","author":"Lefkowitz","year":"1994","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib61","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/1097-0142(19830701)52:1<14::AID-CNCR2820520104>3.0.CO;2-N","article-title":"Intracystic papillary carcinoma of the breast. After mastectomy, radiotherapy or excisional biopsy alone","volume":"52","author":"Carter","year":"1983","journal-title":"Cancer"},{"key":"10.1038\/s41379-020-00706-5_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PAS.0b013e3181fbe20a","article-title":"Intracystic papillary carcinoma of the breast: an in situ or invasive tumor? Results of immunohistochemical analysis and clinical follow-up","volume":"35","author":"Wynveen","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib63","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s00428-006-0305-3","article-title":"Invasive carcinomas of the male breast: a morphologic study of the distribution of histologic subtypes and metastatic patterns in 778 cases","volume":"449","author":"Burga","year":"2006","journal-title":"Virchows Arch"},{"key":"10.1038\/s41379-020-00706-5_bib64","unstructured":"Mac Grogan G, Collins LC, Lerwill M, Rakha EA, Tan BY. Solid papillary carcinoma (in situ and invasive). In: Board WCoTE, editor. WHO classification of breast tumours. 5th ed. Vol. 2. Lyon, France: IARC; 2019. p. 63\u20135."},{"key":"10.1038\/s41379-020-00706-5_bib65","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1097\/00000478-199511000-00003","article-title":"Solid papillary carcinoma of the breast. A form of intraductal carcinoma with endocrine differentiation frequently associated with mucinous carcinoma","volume":"19","author":"Maluf","year":"1995","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib66","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1097\/00000478-199608000-00002","article-title":"Endocrine ductal carcinoma in situ (E-DCIS) of the breast: a form of low-grade DCIS with distinctive clinicopathologic and biologic characteristics","volume":"20","author":"Tsang","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib67","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1365-2559.2007.02849.x","article-title":"Loss of myoepithelium is variable in solid papillary carcinoma of the breast","volume":"51","author":"Nicolas","year":"2007","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00706-5_bib68","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1440-1827.2007.02118.x","article-title":"Solid-papillary carcinoma of the breast: clinicopathological study of 20 cases","volume":"57","author":"Otsuki","year":"2007","journal-title":"Pathol Int"},{"key":"10.1038\/s41379-020-00706-5_bib69","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/00000478-200604000-00011","article-title":"Clinicopathologic analysis of solid papillary carcinoma of the breast and associated invasive carcinomas","volume":"30","author":"Nassar","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib70","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.humpath.2006.02.016","article-title":"Solid papillary ductal carcinoma in situ versus usual ductal hyperplasia in the breast: a potentially difficult distinction resolved by cytokeratin 5\/6","volume":"37","author":"Rabban","year":"2006","journal-title":"Hum Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib71","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1365-2559.1980.tb02957.x","article-title":"Endocrine differentiation in mucoid carcinoma of the breast","volume":"4","author":"Capella","year":"1980","journal-title":"Histopathology"},{"key":"10.1038\/s41379-020-00706-5_bib72","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/path.3032","article-title":"Immunophenotypic and genomic characterization of papillary carcinomas of the breast","volume":"226","author":"Duprez","year":"2012","journal-title":"J Pathol"},{"key":"10.1038\/s41379-020-00706-5_bib73","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.molonc.2014.06.011","article-title":"Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast","volume":"8","author":"Piscuoglio","year":"2014","journal-title":"Mol Oncol"},{"key":"10.1038\/s41379-020-00706-5_bib74","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.breast.2015.12.015","article-title":"Solid papillary carcinoma of the breast: a special entity needs to be distinguished from conventional invasive carcinoma avoiding over-treatment","volume":"26","author":"Guo","year":"2016","journal-title":"Breast"},{"key":"10.1038\/s41379-020-00706-5_bib75","unstructured":"Mac Grogan G, Collins LC, Lerwill M, Rakha EA, Tan BY. Invasive papillary carcinoma. In: Board WCoTE, editor. WHO classification of breast tumours. 5th ed. Vol. 2. Lyon, France: IARC; 2019. p. 66\u20137."},{"key":"10.1038\/s41379-020-00706-5_bib76","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/his.12591","article-title":"High-grade encapsulated papillary carcinoma of the breast: an under-recognized entity","volume":"66","author":"Rakha","year":"2015","journal-title":"Histopathology"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00706-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00706-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222003660?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222003660?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41379-020-00706-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:30:18Z","timestamp":1760229018000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222003660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":76,"alternative-id":["S0893395222003660"],"URL":"https:\/\/doi.org\/10.1038\/s41379-020-00706-5","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Papillary neoplasms of the breast including upgrade rates and management of intraductal papilloma without atypia diagnosed at core needle biopsy","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/s41379-020-00706-5","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}