{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:41:34Z","timestamp":1787002894754,"version":"build-2736575974"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Psychiatry"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1038\/s41380-022-01540-8","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T07:03:17Z","timestamp":1649228597000},"page":"3807-3820","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["An entorhinal-visual cortical circuit regulates depression-like behaviors"],"prefix":"10.1038","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1266-1589","authenticated-orcid":false,"given":"Jian","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhouzhou","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjun","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runan","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Guang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0906-6666","authenticated-orcid":false,"given":"Xiaowei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0081-6048","authenticated-orcid":false,"given":"Peng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4140-7961","authenticated-orcid":false,"given":"Zengcai V.","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"key":"1540_CR1","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","volume":"392","author":"SL James","year":"2018","unstructured":"James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392:1789\u2013858.","journal-title":"Lancet"},{"key":"1540_CR2","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.biopsych.2007.01.018","volume":"62","author":"JP O\u2019Reardon","year":"2007","unstructured":"O\u2019Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, et al. Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: A multisite randomized controlled trial. Biol Psychiatry. 2007;62:1208\u201316.","journal-title":"Biol Psychiatry"},{"key":"1540_CR3","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.brs.2012.08.006","volume":"6","author":"J Downar","year":"2013","unstructured":"Downar J, Daskalakis ZJ. New targets for rTMS in depression: A review of convergent evidence. Brain Stimulation. 2013;6:231\u201340.","journal-title":"Brain Stimulation"},{"key":"1540_CR4","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/S0140-6736(18)30295-2","volume":"391","author":"DM Blumberger","year":"2018","unstructured":"Blumberger DM, Vila-Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, et al. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): A randomised non-inferiority trial. Lancet. 2018;391:1683\u201392.","journal-title":"Lancet"},{"key":"1540_CR5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/s41380-019-0499-9","volume":"25","author":"HW Chase","year":"2020","unstructured":"Chase HW, Boudewyn MA, Carter CS, Phillips ML. Transcranial direct current stimulation: A roadmap for research, from mechanism of action to clinical implementation. Mol Psychiatry. 2020;25:397\u2013407.","journal-title":"Mol Psychiatry"},{"key":"1540_CR6","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.brs.2018.04.012","volume":"11","author":"WF Stubbeman","year":"2018","unstructured":"Stubbeman WF, Zarrabi B, Bastea S, Ragland V, Khairkhah R. Bilateral neuronavigated 20Hz theta burst TMS for treatment refractory depression: An open label study. Brain Stimulation. 2018;11:953\u20135.","journal-title":"Brain Stimulation"},{"key":"1540_CR7","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1056\/NEJMoa1612999","volume":"376","author":"AR Brunoni","year":"2017","unstructured":"Brunoni AR, Moffa AH, Sampaio-Junior B, Borrione L, Moreno ML, Fernandes RA, et al. Trial of electrical direct-current therapy versus escitalopram for depression. N. Engl J Med. 2017;376:2523\u201333.","journal-title":"N. Engl J Med"},{"key":"1540_CR8","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.brs.2014.11.002","volume":"8","author":"N Bakker","year":"2015","unstructured":"Bakker N, Shahab S, Giacobbe P, Blumberger DM, Daskalakis ZJ, Kennedy SH, et al. RTMS of the dorsomedial prefrontal cortex for major depression: Safety, tolerability, effectiveness, and outcome predictors for 10 Hz versus intermittent theta-burst stimulation. Brain Stimulation. 2015;8:208\u201315.","journal-title":"Brain Stimulation"},{"key":"1540_CR9","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1002\/da.23004","volume":"37","author":"LB Razza","year":"2020","unstructured":"Razza LB, Palumbo P, Moffa AH, Carvalho AF, Solmi M, Loo CK, et al. A systematic review and meta-analysis on the effects of transcranial direct current stimulation in depressive episodes. Depression anxiety. 2020;37:594\u2013608.","journal-title":"Depression anxiety"},{"key":"1540_CR10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1001\/jamapsychiatry.2017.4040","volume":"75","author":"B Sampaio","year":"2018","unstructured":"Sampaio B, Tortella G, Borrione L, Moffa AH, Machado-Vieira R, Cretaz E, et al. Efficacy and safety of transcranial direct current stimulation as an add-on treatment for bipolar depression: A randomized clinical trial. JAMA Psychiatry. 2018;75:158\u201366.","journal-title":"JAMA Psychiatry"},{"key":"1540_CR11","doi-asserted-by":"publisher","unstructured":"Zhang Z, Zhang H, Xie CM, Zhang M, Shi Y, Song R, et al. Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex. Sci China Life Sci. 2020. 2020. https:\/\/doi.org\/10.1007\/s11427-020-1730-5.","DOI":"10.1007\/s11427-020-1730-5"},{"key":"1540_CR12","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.pscychresns.2007.11.005","volume":"163","author":"CP Furtado","year":"2008","unstructured":"Furtado CP, Maller JJ, Fitzgerald PB. A magnetic resonance imaging study of the entorhinal cortex in treatment-resistant depression. Psychiatry Res - Neuroimaging. 2008;163:133\u201342.","journal-title":"Psychiatry Res - Neuroimaging"},{"key":"1540_CR13","first-page":"1","volume":"10","author":"Y Kim","year":"2016","unstructured":"Kim Y, Perova Z, Mirrione MM, Pradhan K, Henn FA, Shea S, et al. Whole-brain mapping of neuronal activity in the learned helplessness model of depression. Front Neural Circuits. 2016;10:1\u201311.","journal-title":"Front Neural Circuits"},{"key":"1540_CR14","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1093\/brain\/aww255","volume":"139","author":"W Cheng","year":"2016","unstructured":"Cheng W, Rolls ET, Qiu J, Liu W, Tang Y, Huang CC, et al. Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression. Brain 2016;139:3296\u2013309.","journal-title":"Brain"},{"key":"1540_CR15","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jad.2008.04.021","volume":"113","author":"T Gos","year":"2009","unstructured":"Gos T, G\u00fcnther K, Bielau H, Dobrowolny H, Mawrin C, Tr\u00fcbner K, et al. Suicide and depression in the quantitative analysis of glutamic acid decarboxylase-Immunoreactive neuropil. J Affect Disord. 2009;113:45\u201355.","journal-title":"J Affect Disord"},{"key":"1540_CR16","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1399-5618.2009.00752.x","volume":"11","author":"A Uezato","year":"2009","unstructured":"Uezato A, Meador-Woodruff JH, McCullumsmith RE. Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia. Bipolar Disord. 2009;11:711\u201325.","journal-title":"Bipolar Disord"},{"key":"1540_CR17","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.eurpsy.2008.06.001","volume":"23","author":"TM Michel","year":"2008","unstructured":"Michel TM, Frangou S, Camara S, Thiemeyer D, Jecel J, Tatschner T, et al. Altered glial cell line-derived neurotrophic factor (GDNF) concentrations in the brain of patients with depressive disorder: A comparative post-mortem study. Eur Psychiatry. 2008;23:413\u201320.","journal-title":"Eur Psychiatry"},{"key":"1540_CR18","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/978-3-319-58811-7_12","volume":"17","author":"C Zhang","year":"2017","unstructured":"Zhang C, Lueptow LM, Zhang HT, O\u2019Donnell JM, Xu Y. The role of phosphodiesterase-2 in psychiatric and neurodegenerative disorders. Adv Neurobiol. 2017;17:307\u2013347.","journal-title":"Adv Neurobiol"},{"key":"1540_CR19","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.18632\/aging.102798","volume":"12","author":"X Chen","year":"2020","unstructured":"Chen X, Lan T, Wang Y, He Y, Wu Z, Tian Y, et al. Entorhinal cortex-based metabolic profiling of chronic restraint stress mice model of depression. Aging 2020;12:3042\u201352.","journal-title":"Aging"},{"key":"1540_CR20","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/s41591-018-0002-1","volume":"24","author":"S Yun","year":"2018","unstructured":"Yun S, Reynolds RP, Petrof I, White A, Rivera PD, Segev A, et al. Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive. Nat Med. 2018;24:658\u201366.","journal-title":"Nat Med"},{"key":"1540_CR21","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1056\/NEJMc1203204","volume":"366","author":"K Kobayashi","year":"2012","unstructured":"Kobayashi K, Yoshinaga H, Ohtsuka Y. Memory enhancement and deep-brain stimulation of the entorhinal area. N Engl J Med. 2012;366:1945.","journal-title":"N Engl J Med"},{"key":"1540_CR22","doi-asserted-by":"crossref","first-page":"13469","DOI":"10.1523\/JNEUROSCI.3100-11.2011","volume":"31","author":"SSD Stone","year":"2011","unstructured":"Stone SSD, Teixeira CM, de Vito LM, Zaslavsky K, Josselyn SA, Lozano AM, et al. Stimulation of entorhinal cortex promotes adult neurogenesis and facilitates spatial memory. J Neurosci. 2011;31:13469\u201384.","journal-title":"J Neurosci"},{"key":"1540_CR23","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.neuron.2012.05.027","volume":"75","author":"CS Kim","year":"2012","unstructured":"Kim CS, Chang PY, Johnston D. Enhancement of dorsal hippocampal activity by knockdown of hcn1 channels leads to anxiolytic- and antidepressant-like behaviors. Neuron 2012;75:503\u201316.","journal-title":"Neuron"},{"key":"1540_CR24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-019-11641-8","volume":"10","author":"E Tunc-Ozcan","year":"2019","unstructured":"Tunc-Ozcan E, Peng CY, Zhu Y, Dunlop SR, Contractor A, Kessler JA. Activating newborn neurons suppresses depression and anxiety-like behaviors. Nat Commun. 2019;10:1\u20139.","journal-title":"Nat Commun"},{"key":"1540_CR25","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.neuron.2015.10.041","volume":"88","author":"G S\u00fcrmeli","year":"2015","unstructured":"S\u00fcrmeli G, Marcu DC, McClure C, Garden DLF, Pastoll H, Nolan MF. Molecularly defined circuitry reveals input-output segregation in deep layers of the medial entorhinal cortex. Neuron 2015;88:1040\u201353.","journal-title":"Neuron"},{"key":"1540_CR26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1126\/science.aam6808","volume":"356","author":"T Kitamura","year":"2017","unstructured":"Kitamura T, Ogawa SK, Roy DS, Okuyama T, Morrissey MD, Smith LM, et al. Engrams and circuits crucial for systems consolidation of a memory. Science 2017;356:73\u201378.","journal-title":"Science"},{"key":"1540_CR27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.celrep.2018.06.014","volume":"24","author":"S Ohara","year":"2018","unstructured":"Ohara S, Onodera M, Simonsen \u00d8W, Yoshino R, Hioki H, Iijima T, et al. Intrinsic Projections of Layer Vb Neurons to Layers Va, III, and II in the Lateral and Medial Entorhinal Cortex of the Rat. Cell Rep. 2018;24:107\u201316.","journal-title":"Cell Rep."},{"key":"1540_CR28","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/s41556-020-0475-2","volume":"22","author":"Y Yue","year":"2020","unstructured":"Yue Y, Zong W, Li X, Li J, Zhang Y, Wu R, et al. Long-term, in toto live imaging of cardiomyocyte behaviour during mouse ventricle chamber formation at single-cell resolution. Nat Cell Biol. 2020;22:332\u201340.","journal-title":"Nat Cell Biol"},{"key":"1540_CR29","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1038\/nprot.2011.361","volume":"6","author":"SA Golden","year":"2011","unstructured":"Golden SA, Covington HE, Berton O, Russo SJ. A standardized protocol for repeated social defeat stress in mice. Nat Protoc. 2011;6:1183\u201391.","journal-title":"Nat Protoc"},{"key":"1540_CR30","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.bbrc.2021.03.058","volume":"553","author":"J Lu","year":"2021","unstructured":"Lu J, Gong X, Yao X, Guang Y, Yang H, Ji R, et al. Prolonged chronic social defeat stress promotes less resilience and higher uniformity in depression-like behaviors in adult male mice. Biochemical Biophysical Res Commun. 2021;553:107\u201313.","journal-title":"Biochemical Biophysical Res Commun"},{"key":"1540_CR31","first-page":"1","volume":"11","author":"H Guo","year":"2017","unstructured":"Guo H, Huang ZL, Wang W, Zhang SX, Li J, Cheng K, et al. iTRAQ-based proteomics suggests Ephb6 as a potential regulator of the ERK pathway in the prefrontal cortex of chronic social defeat stress model mice. Proteom - Clin Appl. 2017;11:1\u201312.","journal-title":"Proteom - Clin Appl"},{"key":"1540_CR32","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.lfs.2018.09.016","volume":"211","author":"Y He","year":"2018","unstructured":"He Y, Li W, Tian Y, Chen X, Cheng K, Xu K, et al. iTRAQ-based proteomics suggests LRP6, NPY and NPY2R perturbation in the hippocampus involved in CSDS may induce resilience and susceptibility. Life Sci. 2018;211:102\u201317.","journal-title":"Life Sci"},{"key":"1540_CR33","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/s41593-019-0445-9","volume":"22","author":"B Guo","year":"2019","unstructured":"Guo B, Chen J, Chen Q, Ren K, Feng D, Mao H, et al. Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice. Nat Neurosci. 2019;22:1223\u201334.","journal-title":"Nat Neurosci"},{"key":"1540_CR34","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/nature11270","volume":"488","author":"D Atasoy","year":"2012","unstructured":"Atasoy D, Nicholas Betley J, Su HH, Sternson SM. Deconstruction of a neural circuit for hunger. Nature 2012;488:172\u20137.","journal-title":"Nature"},{"key":"1540_CR35","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/s41591-018-0299-9","volume":"25","author":"CJ Shen","year":"2019","unstructured":"Shen CJ, Zheng D, Li KX, Yang JM, Pan HQ, Yu XD, et al. Cannabinoid CB1 receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbens modulate depressive-like behavior. Nat Med. 2019;25:337\u201349.","journal-title":"Nat Med"},{"key":"1540_CR36","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.brainres.2012.09.043","volume":"1511","author":"MS Farrell","year":"2013","unstructured":"Farrell MS, Roth BL. Pharmacosynthetics: Reimagining the pharmacogenetic approach. Brain Res. 2013;1511:6\u201320.","journal-title":"Brain Res"},{"key":"1540_CR37","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1146\/annurev-neuro-071013-014048","volume":"37","author":"SM Sternson","year":"2014","unstructured":"Sternson SM, Roth BL. Chemogenetic tools to interrogate brain functions. Annu Rev Neurosci. 2014;37:387\u2013407.","journal-title":"Annu Rev Neurosci"},{"key":"1540_CR38","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.cell.2014.05.017","volume":"157","author":"LA Gunaydin","year":"2014","unstructured":"Gunaydin LA, Grosenick L, Finkelstein JC, Kauvar IV, Fenno LE, Adhikari A, et al. Natural neural projection dynamics underlying social behavior. Cell 2014;157:1535\u201351.","journal-title":"Cell"},{"key":"1540_CR39","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1038\/nprot.2014.080","volume":"9","author":"G Cui","year":"2014","unstructured":"Cui G, Jun SB, Jin X, Luo G, Pham MD, Lovinger DM, et al. Deep brain optical measurements of cell type-specific neural activity in behaving mice. Nat Protoc. 2014;9:1213\u201328.","journal-title":"Nat Protoc"},{"key":"1540_CR40","doi-asserted-by":"crossref","first-page":"8863","DOI":"10.1523\/JNEUROSCI.1181-17.2017","volume":"37","author":"W Zhong","year":"2017","unstructured":"Zhong W, Li Y, Feng Q, Luo M. Learning and stress shape the reward response patterns of serotonin neurons. J Neurosci. 2017;37:8863\u201375.","journal-title":"J Neurosci"},{"key":"1540_CR41","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/j.cell.2016.05.007","volume":"165","author":"N Renier","year":"2016","unstructured":"Renier N, Adams EL, Kirst C, Wu Z, Azevedo R, Kohl J, et al. Mapping of brain activity by automated volume analysis of immediate early genes. Cell 2016;165:1789\u2013802.","journal-title":"Cell"},{"key":"1540_CR42","doi-asserted-by":"crossref","first-page":"732464","DOI":"10.3389\/fnana.2021.732464","volume":"15","author":"Z Zhang","year":"2021","unstructured":"Zhang Z, Yao X, Yin X, Ding Z, Huang T, Huo Y, et al. Multi-Scale Light-Sheet Fluorescence Microsc Fast Whole Brain Imaging. Front Neuroanat. 2021;15:732464.","journal-title":"Front Neuroanat"},{"key":"1540_CR43","doi-asserted-by":"crossref","first-page":"5163","DOI":"10.1073\/pnas.0700293104","volume":"104","author":"BN Armbruster","year":"2007","unstructured":"Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL. Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc Natl Acad Sci USA. 2007;104:5163\u20138.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1540_CR44","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/s41592-019-0435-6","volume":"16","author":"H Dana","year":"2019","unstructured":"Dana H, Sun Y, Mohar B, Hulse BK, Kerlin AM, Hasseman JP, et al. High-performance calcium sensors for imaging activity in neuronal populations and microcompartments. Nat Methods. 2019;16:649\u201357.","journal-title":"Nat Methods"},{"key":"1540_CR45","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.neuron.2019.01.037","volume":"102","author":"L Huang","year":"2019","unstructured":"Huang L, Xi Y, Peng Y, Yang Y, Huang X, Fu Y, et al. A visual circuit related to habenula underlies the antidepressive effects of light therapy. Neuron 2019;102:128\u201342.e8.","journal-title":"Neuron"},{"key":"1540_CR46","doi-asserted-by":"publisher","unstructured":"An K, Zhao H, Miao Y, Xu Q, Li Y, Ma Y, et al. A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice. Nat Neurosci. 2020. June 1, 2020. https:\/\/doi.org\/10.1038\/s41593-020-0640-8.","DOI":"10.1038\/s41593-020-0640-8"},{"key":"1540_CR47","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.neuron.2019.05.027","volume":"103","author":"Z Zhou","year":"2019","unstructured":"Zhou Z, Liu X, Chen S, Zhang Z, Liu Y, Montardy Q, et al. A VTA GABAergic neural circuit mediates visually evoked innate defensive responses. Neuron 2019;103:473\u201388.e6.","journal-title":"Neuron"},{"key":"1540_CR48","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.neuron.2013.01.020","volume":"77","author":"AM Lozano","year":"2013","unstructured":"Lozano AM, Lipsman N. Probing and regulating dysfunctional circuits using deep brain stimulation. Neuron 2013;77:406\u201324.","journal-title":"Neuron"},{"key":"1540_CR49","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/nature22324","volume":"545","author":"ZV Guo","year":"2017","unstructured":"Guo ZV, Inagaki HK, Daie K, Druckmann S, Gerfen CR, Svoboda K. Maintenance of persistent activity in a frontal thalamocortical loop. Nature 2017;545:181\u20136.","journal-title":"Nature"},{"key":"1540_CR50","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1038\/mp.2015.176","volume":"21","author":"FR Carreno","year":"2016","unstructured":"Carreno FR, Donegan JJ, Boley AM, Shah A, DeGuzman M, Frazer A, et al. Activation of a ventral hippocampus-medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine. Mol Psychiatry. 2016;21:1298\u2013308.","journal-title":"Mol Psychiatry"},{"key":"1540_CR51","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.neuron.2016.01.011","volume":"89","author":"N Padilla-Coreano","year":"2016","unstructured":"Padilla-Coreano N, Bolkan SS, Pierce GM, Blackman DR, Hardin WD, Garcia-Garcia AL, et al. Direct ventral hippocampal-prefrontal input is required for anxiety-related neural activity and behavior. Neuron 2016;89:857\u201366.","journal-title":"Neuron"},{"key":"1540_CR52","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/nature11617","volume":"492","author":"MR Warden","year":"2012","unstructured":"Warden MR, Selimbeyoglu A, Mirzabekov JJ, Lo M, Thompson KR, Kim SY, et al. A prefrontal cortex-brainstem neuronal projection that controls response to behavioural challenge. Nature 2012;492:428\u201332.","journal-title":"Nature"},{"key":"1540_CR53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-019-13993-7","volume":"11","author":"G Pi","year":"2020","unstructured":"Pi G, Gao D, Wu D, Wang Y, Lei H, Zeng W, et al. Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect. Nat Commun. 2020;11:1\u201315.","journal-title":"Nat Commun"},{"key":"1540_CR54","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nature25509","volume":"554","author":"Y Yang","year":"2018","unstructured":"Yang Y, Cui Y, Sang K, Dong Y, Ni Z, Ma S, et al. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression. Nature 2018;554:317\u201322.","journal-title":"Nature"},{"key":"1540_CR55","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nature25752","volume":"554","author":"Y Cui","year":"2018","unstructured":"Cui Y, Yang Y, Ni Z, Dong Y, Cai G, Foncelle A, et al. Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression. Nature 2018;554:323\u20137.","journal-title":"Nature"},{"key":"1540_CR56","doi-asserted-by":"crossref","first-page":"5792","DOI":"10.1073\/pnas.1801837115","volume":"115","author":"CD Proulx","year":"2018","unstructured":"Proulx CD, Aronson S, Milivojevic D, Molina C, Loi A, Monk B, et al. A neural pathway controlling motivation to exert effort. Proc Natl Acad Sci USA. 2018;115:5792\u20137.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1540_CR57","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1038\/s41593-019-0469-1","volume":"22","author":"DA Gehrlach","year":"2019","unstructured":"Gehrlach DA, Dolensek N, Klein AS, Roy Chowdhury R, Matthys A, Jungh\u00e4nel M, et al. Aversive state processing in the posterior insular cortex. Nat Neurosci. 2019;22:1424\u201337.","journal-title":"Nat Neurosci"},{"key":"1540_CR58","doi-asserted-by":"crossref","first-page":"7062","DOI":"10.1038\/ncomms8062","volume":"6","author":"RC Bagot","year":"2015","unstructured":"Bagot RC, Parise EM, Pe\u00f1a CJ, Zhang HX, Maze I, Chaudhury D, et al. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nat Commun. 2015;6:7062.","journal-title":"Nat Commun"},{"key":"1540_CR59","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1093\/cercor\/bht131","volume":"24","author":"N Salminen-Vaparanta","year":"2014","unstructured":"Salminen-Vaparanta N, Vanni S, Noreika V, Valiulis V, M\u00f3r\u00f3 L, Revonsuo A. Subjective characteristics of TMS-induced phosphenes originating in human V1 and V2. Cereb Cortex. 2014;24:2751\u201360.","journal-title":"Cereb Cortex"},{"key":"1540_CR60","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/mp.2016.60","volume":"22","author":"L Schmaal","year":"2017","unstructured":"Schmaal L, Hibar DP, S\u00e4mann PG, Hall GB, Baune BT, Jahanshad N, et al. Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA major depressive disorder working group. Mol Psychiatry. 2017;22:900\u20139.","journal-title":"Mol Psychiatry"},{"key":"1540_CR61","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.biopsych.2009.10.027","volume":"67","author":"D Maciag","year":"2010","unstructured":"Maciag D, Hughes J, O\u2019Dwyer G, Pride Y, Stockmeier CA, Sanacora G, et al. Reduced density of Calbindin Immunoreactive GABAergic neurons in the occipital cortex in major depression: Relevance to neuroimaging studies. Biol Psychiatry. 2010;67:465\u201370.","journal-title":"Biol Psychiatry"},{"key":"1540_CR62","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1523\/JNEUROSCI.3341-08.2009","volume":"29","author":"M Desseilles","year":"2009","unstructured":"Desseilles M, Balteau E, Sterpenich V, Thien TDV, Darsaud A, Vandewalle G, et al. Abnormal neural filtering of irrelevant visual information in depression. J Neurosci. 2009;29:1395\u2013403.","journal-title":"J Neurosci"},{"key":"1540_CR63","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1001\/2013.jamapsychiatry.60","volume":"70","author":"ML Furey","year":"2013","unstructured":"Furey ML, Drevets WC, Hoffman EM, Frankel E, Speer AM, Zarate CA. Potential of pretreatment neural activity in the visual cortex during emotional processing to predict treatment response to scopolamine in major depressive disorder. JAMA Psychiatry. 2013;70:280\u201390.","journal-title":"JAMA Psychiatry"},{"key":"1540_CR64","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/dneu.20758","volume":"70","author":"E Castr\u00e9n","year":"2010","unstructured":"Castr\u00e9n E, Rantam\u00e4ki T. The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity. Developmental Neurobiol. 2010;70:289\u201397.","journal-title":"Developmental Neurobiol"},{"key":"1540_CR65","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nature26159","volume":"556","author":"Y Han","year":"2018","unstructured":"Han Y, Kebschull JM, Campbell RAA, Cowan D, Imhof F, Zador AM, et al. The logic of single-cell projections from visual cortex. Nature 2018;556:51\u20136.","journal-title":"Nature"}],"updated-by":[{"DOI":"10.1038\/s41380-022-01584-w","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000}}],"container-title":["Molecular Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41380-022-01540-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41380-022-01540-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41380-022-01540-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T06:04:20Z","timestamp":1680847460000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41380-022-01540-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,6]]},"references-count":65,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["1540"],"URL":"https:\/\/doi.org\/10.1038\/s41380-022-01540-8","relation":{},"ISSN":["1359-4184","1476-5578"],"issn-type":[{"value":"1359-4184","type":"print"},{"value":"1476-5578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,6]]},"assertion":[{"value":"20 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2022","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1038\/s41380-022-01584-w","URL":"https:\/\/doi.org\/10.1038\/s41380-022-01584-w","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}