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ABCB has received lecture and consulting fees from Asofarma and Exeltis. MLP has served on an advisory board for Janssen and has received grant support from ANID FONDECYT Regular 1181365, FONDEF ID19I10116 and Basal Funding for Scientific and Technological Center of Excellence, IMPACT, #FB210024. MAF reports the following conflicts of interest: grant support from Assurex Health and Mayo Foundation; CME\/travel\/honoraria from Carnot Laboratories, American Physician Institute; and financial interest\/stock ownership\/royalties in Chymia LLC. All other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}