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Postmortem DLPFC samples were collected by the University of Texas Health Science Center at Houston (UTHealth Houston) Brain Collection, in collaboration with the Harris Country Institute of Forensic Science and with approval from the Institutional Review Board (IRB HSC-MS-15-0247 -\n                      The UTHealth Brain Collection for Research in Psychiatric Disorders\n                      ). Informed consent for postmortem sample donation for scientific research was obtained from all donors next of kin. Procedures involving oocyte extraction from\n                      Xenopus laevis\n                      were completed in compliance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and the IACUC at the University of Texas Medical Branch at Galveston (IACUC:1803024).","order":2,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"During the preparation of this work the author(s) used ChatGPT to optimize the R codes used in the Euclidian distance\/multi-omic reorganization analysis (Supplementary Data\u00a0\n                      \n                      \u2013\n                      \n                      ) and the Cliff\u2019s delta conversion to Cohen\u2019s d (Supplementary Data\u00a0\n                      \n                      ). After using this tool\/service, the author(s) reviewed and validated the accuracy of code against analyses that were manually completed using Microsoft Excel, JMP Pro 16, GraphPad Prism calculating tools. Authors take full responsibility for the content of this publication.","order":3,"name":"Ethics","label":"AI Disclosure","group":{"name":"EthicsHeading","label":"Ethics"}}]}}