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Prof. YK Wing received personal fees from Eisai for delivering a lecture and sponsorship from Lundbeck and Aculys Pharma, Japan, and participated in a research contract project with Takeda company. Dr. Jing Wang was supported by the National Natural Science Foundation of China (82401742) and Guangdong Basic and Applied Basic Research Foundation (2024A1515011349). Dr Filip Scheperjans reports consultancies (Abbvie, Axial Biotherapeutics, Orion Pharma, Teva, Adamant Health, Merz), honoraria (Abbvie, GE Healthcare, Merck, Teva, Bristol Myers Squibb, Sanofi, Biocodex, Biogen), grants (Emil Aaltonen Foundation, Konung Gustav V:s och Drottning Victorias Stiftelse, Olvi Foundation, Yrj\u00f6 Jahnsson Foundation, Stockmann Foundation, Sigrid Juselius Foundation, Research Council of Finland, Hospital District of Helsinki and Uusimaa, Renishaw, Orion Pharma, Abbvie), travel expenses (Lundbeck, NordicInfucare), stock (NeuroInnovation Oy, NeuroBiome Oy, Axial Biotherapeutics). The other authors report no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}