{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T12:03:27Z","timestamp":1793361807347,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T00:00:00Z","timestamp":1555372800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T00:00:00Z","timestamp":1555372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["IL 60637"],"award-info":[{"award-number":["IL 60637"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol."],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1038\/s41386-019-0393-9","type":"journal-article","created":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T19:07:48Z","timestamp":1555355268000},"page":"1354-1361","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":271,"title":["Impulsivity in Gambling Disorder and problem gambling: a meta-analysis"],"prefix":"10.1038","volume":"44","author":[{"given":"Konstantinos","family":"Ioannidis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxanne","family":"Hook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Wickham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon E.","family":"Grant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7014-8121","authenticated-orcid":false,"given":"Samuel R.","family":"Chamberlain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,4,16]]},"reference":[{"key":"393_CR1","doi-asserted-by":"publisher","first-page":"1874","DOI":"10.1016\/S0140-6736(10)62185-X","volume":"378","author":"DC Hodgins","year":"2011","unstructured":"Hodgins DC, Stea JN, Grant JE. Gambling disorders. Lancet. 2011;378:1874\u201384.","journal-title":"Lancet"},{"key":"393_CR2","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1111\/j.1360-0443.2012.04087.x","volume":"108","author":"NM Petry","year":"2013","unstructured":"Petry NM, et al. An empirical evaluation of proposed changes for gambling diagnosis in the DSM-5. Addiction. 2013;108:575\u201381.","journal-title":"Addiction"},{"key":"393_CR3","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/ajad.12214","volume":"24","author":"EN Peters","year":"2015","unstructured":"Peters EN, et al. Relationship of gambling with tobacco, alcohol, and illicit drug use among adolescents in the USA: Review of the literature 2000-2014. Am J Addict. 2015;24:206\u201316.","journal-title":"Am J Addict"},{"key":"393_CR4","doi-asserted-by":"crossref","unstructured":"Yucel, M et al. A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study. Addiction, 2018. [Epub ahead of print].","DOI":"10.1111\/add.14424"},{"key":"393_CR5","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/j.conb.2013.01.004","volume":"23","author":"L Clark","year":"2013","unstructured":"Clark L, Limbrick-Oldfield EH. Disordered gambling: a behavioral addiction. Curr Opin Neurobiol. 2013;23:655\u20139.","journal-title":"Curr Opin Neurobiol"},{"key":"393_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S1092852918001244","volume":"21","author":"J Tiego","year":"2018","unstructured":"Tiego J, et al. Overlapping dimensional phenotypes of impulsivity and compulsivity explain co-occurrence of addictive and related behaviors. CNS Spectr. 2018;21:1\u201315.","journal-title":"CNS Spectr"},{"key":"393_CR7","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1007\/PL00005481","volume":"146","author":"JL Evenden","year":"1999","unstructured":"Evenden JL. Varieties of impulsivity. Psychopharmacol (Berl). 1999;146:348\u201361.","journal-title":"Psychopharmacol (Berl)"},{"key":"393_CR8","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1080\/13803395.2017.1313393","volume":"40","author":"L Rochat","year":"2018","unstructured":"Rochat L, et al. A multifactorial and integrative approach to impulsivity in neuropsychology: insights from the UPPS model of impulsivity. J Clin Exp Neuropsychol. 2018;40:45\u201361.","journal-title":"J Clin Exp Neuropsychol"},{"key":"393_CR9","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.neubiorev.2016.08.033","volume":"71","author":"M Brand","year":"2016","unstructured":"Brand M, et al. Integrating psychological and neurobiological considerations regarding the development and maintenance of specific Internet-use disorders: an Interaction of Person-Affect-Cognition-Execution (I-PACE) model. Neurosci Biobehav Rev. 2016;71:252\u201366.","journal-title":"Neurosci Biobehav Rev"},{"key":"393_CR10","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.psychres.2014.12.061","volume":"226","author":"DW Black","year":"2015","unstructured":"Black DW, et al. The relationship of DSM-IV pathological gambling to compulsive buying and other possible spectrum disorders: results from the Iowa PG family study. Psychiatry Res. 2015;226:273\u20136.","journal-title":"Psychiatry Res"},{"key":"393_CR11","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1007\/s10899-014-9505-y","volume":"31","author":"DW Black","year":"2015","unstructured":"Black DW, et al. Personality disorders, impulsiveness, and novelty seeking in persons with DSM-IV pathological gambling and their first-degree relatives. J Gambl Stud. 2015;31:1201\u201314.","journal-title":"J Gambl Stud"},{"key":"393_CR12","doi-asserted-by":"publisher","first-page":"3361","DOI":"10.1007\/s00213-016-4372-0","volume":"233","author":"J MacKillop","year":"2016","unstructured":"MacKillop J, et al. The latent structure of impulsivity: impulsive choice, impulsive action, and impulsive personality traits. Psychopharmacol (Berl). 2016;233:3361\u201370.","journal-title":"Psychopharmacol (Berl)"},{"key":"393_CR13","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.comppsych.2016.04.010","volume":"68","author":"SR Chamberlain","year":"2016","unstructured":"Chamberlain SR, et al. Are obsessive-compulsive symptoms impulsive, compulsive or both?. Compr Psychiatry. 2016;68:111\u20138.","journal-title":"Compr Psychiatry"},{"key":"393_CR14","doi-asserted-by":"publisher","first-page":"609","DOI":"10.2307\/1126908","volume":"36","author":"J Kagan","year":"1965","unstructured":"Kagan J. Reflection-impulsivity and reading ability in primary grade children. Child Dev. 1965;36:609\u201328.","journal-title":"Child Dev"},{"key":"393_CR15","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.3389\/fpsyg.2018.01339","volume":"9","author":"J Tiego","year":"2018","unstructured":"Tiego J, et al. A hierarchical model of inhibitory control. Front Psychol. 2018;9:1339.","journal-title":"Front Psychol"},{"key":"393_CR16","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1038\/nrn.2017.8","volume":"18","author":"JW Dalley","year":"2017","unstructured":"Dalley JW, Robbins TW. Fractionating impulsivity: neuropsychiatric implications. Nat Rev Neurosci. 2017;18:158\u201371.","journal-title":"Nat Rev Neurosci"},{"key":"393_CR17","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1017\/S0033291717002185","volume":"48","author":"SR Chamberlain","year":"2018","unstructured":"Chamberlain SR, et al. Latent traits of impulsivity and compulsivity: toward dimensional psychiatry. Psychol Med. 2018;48:810\u201321.","journal-title":"Psychol Med"},{"key":"393_CR18","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1111\/add.13535","volume":"112","author":"M Amlung","year":"2017","unstructured":"Amlung M, et al. Steep delay discounting and addictive behavior: a meta-analysis of continuous associations. Addiction. 2017;112:51\u201362.","journal-title":"Addiction"},{"key":"393_CR19","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.drugalcdep.2017.09.023","volume":"181","author":"I Kovacs","year":"2017","unstructured":"Kovacs I, et al. Decision making measured by the Iowa Gambling Task in alcohol use disorder and gambling disorder: a systematic review and meta-analysis. Drug Alcohol Depend. 2017;181:152\u201361.","journal-title":"Drug Alcohol Depend"},{"key":"393_CR20","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.psychres.2011.05.034","volume":"189","author":"JE Grant","year":"2011","unstructured":"Grant JE, et al. Selective decision-making deficits in at-risk gamblers. Psychiatry Res. 2011;189:115\u201320.","journal-title":"Psychiatry Res"},{"key":"393_CR21","doi-asserted-by":"publisher","first-page":"2008","DOI":"10.1001\/jama.283.15.2008","volume":"283","author":"DF Stroup","year":"2000","unstructured":"Stroup DF, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283:2008\u201312.","journal-title":"JAMA"},{"key":"393_CR22","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1097\/00146965-200303000-00006","volume":"16","author":"M Regard","year":"2003","unstructured":"Regard M, et al. Brain damage and addictive behavior: a neuropsychological and electroencephalogram investigation with pathologic gamblers. Cogn Behav Neurol. 2003;16:47\u201353.","journal-title":"Cogn Behav Neurol"},{"key":"393_CR23","doi-asserted-by":"publisher","first-page":"pii: ENEURO.015","DOI":"10.1523\/ENEURO.0159-17.2017","volume":"4","author":"A Wiehler","year":"2017","unstructured":"Wiehler A, et al. Episodic tags enhance striatal valuation signals during temporal discounting in pathological gamblers. eNeuro. 2017;4:pii: ENEURO.0159-17.2017.","journal-title":"eNeuro"},{"key":"393_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v036.i03","volume":"36","author":"W Viechtbauer","year":"2010","unstructured":"Viechtbauer W. Conducting meta-analyses in R with the metafor package. J Stat Softw. 2010;36:1\u201348.","journal-title":"J Stat Softw"},{"key":"393_CR25","doi-asserted-by":"publisher","DOI":"10.1038\/srep39233","volume":"6","author":"WS Yan","year":"2016","unstructured":"Yan WS, et al. Comparison of impulsivity in non-problem, at-risk and problem gamblers. Sci Rep. 2016;6:39233.","journal-title":"Sci Rep"},{"key":"393_CR26","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1016\/j.addbeh.2014.04.022","volume":"39","author":"JE Grant","year":"2014","unstructured":"Grant JE, Chamberlain SR. Impulsive action and impulsive choice across substance and behavioral addictions: cause or consequence?. Addict Behav. 2014;39:1632\u20139.","journal-title":"Addict Behav"},{"key":"393_CR27","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1159\/000362839","volume":"70","author":"N Romanczuk-Seiferth","year":"2014","unstructured":"Romanczuk-Seiferth N, van den Brink W, Goudriaan AE. From symptoms to neurobiology: pathological gambling in the light of the new classification in DSM-5. Neuropsychobiology. 2014;70:95\u2013102.","journal-title":"Neuropsychobiology"},{"key":"393_CR28","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1111\/adb.12378","volume":"22","author":"M Fauth-Buhler","year":"2017","unstructured":"Fauth-Buhler M, Mann K, Potenza MN. Pathological gambling: a review of the neurobiological evidence relevant for its classification as an addictive disorder. Addict Biol. 2017;22:885\u201397.","journal-title":"Addict Biol"},{"key":"393_CR29","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s11469-015-9572-z","volume":"13","author":"DC Hodgins","year":"2015","unstructured":"Hodgins DC, Holub A. Components of impulsivity in gambling disorder. Int J Ment Health Addict. 2015;13:699\u2013711.","journal-title":"Int J Ment Health Addict"},{"key":"393_CR30","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1111\/add.12946","volume":"110","author":"C Blanco","year":"2015","unstructured":"Blanco C, et al. Towards a comprehensive developmental model of pathological gambling. Addiction. 2015;110:1340\u201351.","journal-title":"Addiction"},{"key":"393_CR31","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1038\/d41586-018-02568-z","volume":"555","author":"MN Potenza","year":"2018","unstructured":"Potenza MN, Higuchi S, Brand M. Call for research into a wider range of behavioural addictions. Nature. 2018;555:30.","journal-title":"Nature"},{"key":"393_CR32","doi-asserted-by":"crossref","unstructured":"Chamberlain, SR et al. Fractionation of impulsive and compulsive trans-diagnostic phenotypes and their longitudinal associations. BioRxIV, Australian and New Zealand Journal of Psychiatry, In Press, 2019.","DOI":"10.1177\/0004867419844325"},{"key":"393_CR33","doi-asserted-by":"crossref","unstructured":"Parkes, L et al. Transdiagnostic variations in impulsivity and compulsivity in obsessive-compulsive disorder and gambling disorder correlate with effective connectivity in cortical-striatal-thalamic-cortical circuits. BioRxIV, 2019.","DOI":"10.1101\/389320"},{"key":"393_CR34","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1016\/j.jpsychires.2012.05.013","volume":"46","author":"JE Grant","year":"2012","unstructured":"Grant JE, et al. Gender-related clinical and neurocognitive differences in individuals seeking treatment for pathological gambling. J Psychiatr Res. 2012;46:1206\u201311.","journal-title":"J Psychiatr Res"},{"key":"393_CR35","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1177\/0004867415583339","volume":"49","author":"GC Medeiros","year":"2015","unstructured":"Medeiros GC, et al. The importance of cross-cultural research in addictions. Aust N Z J Psychiatry. 2015;49:851.","journal-title":"Aust N Z J Psychiatry"},{"key":"393_CR36","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1111\/j.1360-0443.2009.02533.x","volume":"104","author":"AJ Lawrence","year":"2009","unstructured":"Lawrence AJ, et al. Problem gamblers share deficits in impulsive decision-making with alcohol-dependent individuals. Addiction. 2009;104:1006\u201315.","journal-title":"Addiction"},{"key":"393_CR37","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s10899-017-9709-z","volume":"34","author":"N Bonini","year":"2018","unstructured":"Bonini N, et al. Reduced risk-taking after prior losses in pathological gamblers under treatment and healthy control group but not in problem gamblers. J Gambl Stud. 2018;34:429\u201347.","journal-title":"J Gambl Stud"},{"key":"393_CR38","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.psychres.2004.10.003","volume":"133","author":"M Brand","year":"2005","unstructured":"Brand M, et al. Decision-making impairments in patients with pathological gambling. Psychiatry Res. 2005;133:91\u20139.","journal-title":"Psychiatry Res"},{"key":"393_CR39","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1017\/S0033291713001803","volume":"44","author":"NY Shin","year":"2014","unstructured":"Shin NY, et al. Cognitive functioning in obsessive-compulsive disorder: a meta-analysis. Psychol Med. 2014;44:1121\u201330.","journal-title":"Psychol Med"},{"key":"393_CR40","doi-asserted-by":"publisher","first-page":"2029","DOI":"10.1017\/S0033291713002535","volume":"44","author":"PL Rock","year":"2014","unstructured":"Rock PL, et al. Cognitive impairment in depression: a systematic review and meta-analysis. Psychol Med. 2014;44:2029\u201340.","journal-title":"Psychol Med"},{"key":"393_CR41","doi-asserted-by":"publisher","first-page":"e65566","DOI":"10.1371\/journal.pone.0065566","volume":"8","author":"SA De Brito","year":"2013","unstructured":"De Brito SA, et al. Cool and hot executive function impairments in violent offenders with antisocial personality disorder with and without psychopathy. PLoS ONE. 2013;8:e65566.","journal-title":"PLoS One"},{"key":"393_CR42","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.neubiorev.2017.11.022","volume":"84","author":"T van Timmeren","year":"2018","unstructured":"van Timmeren T, et al. Compulsivity-related neurocognitive performance deficits in gambling disorder: a systematic review and meta-analysis. Neurosci Biobehav Rev. 2018;84:204\u201317.","journal-title":"Neurosci Biobehav Rev"}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41386-019-0393-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41386-019-0393-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41386-019-0393-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T17:06:08Z","timestamp":1684602368000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41386-019-0393-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,16]]},"references-count":42,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["393"],"URL":"https:\/\/doi.org\/10.1038\/s41386-019-0393-9","relation":{},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,16]]},"assertion":[{"value":"10 February 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}