{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:40:03Z","timestamp":1790725203355,"version":"4.1.0"},"reference-count":100,"publisher":"Springer Science and Business Media LLC","issue":"13","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100005640","name":"Faculdade de Medicina da Universidade de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2017\/19237-1"],"award-info":[{"award-number":["2017\/19237-1"]}],"id":[{"id":"10.13039\/501100005640","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol."],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1038\/s41386-021-01080-9","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T14:05:25Z","timestamp":1625061925000},"page":"2257-2265","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Treatment of mixed depression with theta-burst stimulation (TBS): results from a double-blind, randomized, sham-controlled clinical trial"],"prefix":"10.1038","volume":"46","author":[{"given":"Diego Freitas","family":"Tavares","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Suen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla Garcia","family":"Rodrigues dos Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris Hupfeld","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro Da Costa","family":"Lane Valiengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5345-9689","authenticated-orcid":false,"given":"Izio","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7367-2882","authenticated-orcid":false,"given":"Lucas","family":"Borrione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Marques Forte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6310-3571","authenticated-orcid":false,"given":"Andr\u00e9 R.","family":"Brunoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9843-3442","authenticated-orcid":false,"given":"Ricardo","family":"Alberto Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"1080_CR1","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1111\/bdi.12423","volume":"18","author":"AJ Ferrari","year":"2016","unstructured":"Ferrari AJ, Stockings E, Khoo JP, Erskine HE, Degenhardt L, Vos T, et al. The prevalence and burden of bipolar disorder: findings from the Global Burden of Disease Study 2013. Bipolar Disord. 2016;18:440\u201350.","journal-title":"Bipolar Disord"},{"key":"1080_CR2","doi-asserted-by":"publisher","first-page":"e1001547","DOI":"10.1371\/journal.pmed.1001547","volume":"10","author":"AJ Ferrari","year":"2013","unstructured":"Ferrari AJ, Charlson FJ, Norman RE, Patten SB, Freedman G, Murray CJ, et al. Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS med. 2013;10:e1001547.","journal-title":"PLoS med"},{"key":"1080_CR3","doi-asserted-by":"crossref","unstructured":"Verdolini N, Agius M, Ferranti L, Moretti P, Piselli M, Quartesan R. The state of the art of the DSM-5 \u201cwith mixed features\u201d specifier. The Scientific World Journal. 2015;2015::757258.","DOI":"10.1155\/2015\/757258"},{"key":"1080_CR4","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.jad.2013.04.025","volume":"150","author":"R McIntyre","year":"2013","unstructured":"McIntyre R, Tohen M, Berk M, Zhao J, Weiller E. DSM-5 mixed specifier for manic episodes: evaluating the effect of depressive features on severity and treatment outcome using asenapine clinical trial data. J Affect Disord. 2013;150:378\u201383.","journal-title":"J Affect Disord"},{"key":"1080_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2194-7511-1-21","volume":"1","author":"T Hergueta","year":"2013","unstructured":"Hergueta T, Weiller E. Evaluating depressive symptoms in hypomanic and manic episodes using a structured diagnostic tool: validation of a new Mini International Neuropsychiatric Interview (MINI) module for the DSM-5\u2019With Mixed Features\u2019 specifier. Int J bipolar Disord. 2013;1:1\u201310.","journal-title":"Int J bipolar Disord"},{"key":"1080_CR6","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/pcn.12213","volume":"69","author":"M Takeshima","year":"2015","unstructured":"Takeshima M, Oka T. DSM\u20105\u2010defined \u2018mixed features\u2019 and B enazzi\u2019s mixed depression: which is practically useful to discriminate bipolar disorder from unipolar depression in patients with depression? Psychiatry Clin Neurosci. 2015;69:109\u201316.","journal-title":"Psychiatry Clin Neurosci"},{"key":"1080_CR7","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/bdi.12609","volume":"20","author":"LN Yatham","year":"2018","unstructured":"Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018;20:97\u2013170.","journal-title":"Bipolar Disord"},{"key":"1080_CR8","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.jad.2014.09.026","volume":"172","author":"RS McIntyre","year":"2015","unstructured":"McIntyre RS, Soczynska JK, Cha DS, Woldeyohannes HO, Dale RS, Alsuwaidan MT, et al. The prevalence and illness characteristics of DSM-5-defined \u201cmixed feature specifier\u201d in adults with major depressive disorder and bipolar disorder: results from the International Mood Disorders Collaborative Project. J Affect Disord. 2015;172:259\u201364.","journal-title":"J Affect Disord"},{"key":"1080_CR9","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1001\/archgenpsychiatry.2009.158","volume":"66","author":"P Zimmermann","year":"2009","unstructured":"Zimmermann P, Br\u00fcckl T, Nocon A, Pfister H, Lieb R, Wittchen H-U, et al. Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity. Arch Gen psychiatry. 2009;66:1341\u201352.","journal-title":"Arch Gen psychiatry"},{"key":"1080_CR10","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1176\/appi.ajp.2008.08050746","volume":"166","author":"JF Goldberg","year":"2009","unstructured":"Goldberg JF, Perlis RH, Bowden CL, Thase ME, Miklowitz DJ, Marangell LB, et al. Manic symptoms during depressive episodes in 1380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry. 2009;166:173\u201381.","journal-title":"Am J Psychiatry"},{"key":"1080_CR11","doi-asserted-by":"publisher","first-page":"351","DOI":"10.4088\/JCP.14m09092","volume":"76","author":"G Perugi","year":"2015","unstructured":"Perugi G, Angst J, Azorin J-M, Bowden CL, Mosolov S, Reis J, et al. Mixed features in patients with a major depressive episode: the BRIDGE-II-MIX study. The. J Clin psychiatry. 2015;76:351\u201358.","journal-title":"J Clin psychiatry"},{"key":"1080_CR12","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1111\/bdi.12338","volume":"17","author":"D Popovic","year":"2015","unstructured":"Popovic D, Vieta E, Azorin JM, Angst J, Bowden CL, Mosolov S, et al. Suicide attempts in major depressive episode: evidence from the BRIDGE\u2010II\u2010Mix study. Bipolar Disord. 2015;17:795\u2013803.","journal-title":"Bipolar Disord"},{"key":"1080_CR13","first-page":"434","volume":"31","author":"G Tavormina","year":"2019","unstructured":"Tavormina G. Bipolar disorders and bipolarity: the notion of the \u201cmixity\u201d. Psychiatr Danubina. 2019;31:434\u20137.","journal-title":"Psychiatr Danubina"},{"key":"1080_CR14","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.smrv.2018.02.002","volume":"41","author":"F Talih","year":"2018","unstructured":"Talih F, Gebara NY, Andary FS, Mondello S, Kobeissy F, Ferri R. Delayed sleep phase syndrome and bipolar disorder: pathogenesis and available common biomarkers. Sleep Med Rev. 2018;41:133\u201340.","journal-title":"Sleep Med Rev"},{"key":"1080_CR15","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.jad.2014.10.061","volume":"173","author":"IH Shim","year":"2015","unstructured":"Shim IH, Woo YS, Bahk W-M. Prevalence rates and clinical implications of bipolar disorder \u201cwith mixed features\u201d as defined by DSM-5. J Affect Disord. 2015;173:120\u201325.","journal-title":"J Affect Disord"},{"key":"1080_CR16","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/acps.12896","volume":"138","author":"N Verdolini","year":"2018","unstructured":"Verdolini N, Hidalgo\u2010Mazzei D, Murru A, Pacchiarotti I, Samalin L, Young A, et al. Mixed states in bipolar and major depressive disorders: systematic review and quality appraisal of guidelines. Acta Psychiatr Scandinavica. 2018;138:196\u2013222.","journal-title":"Acta Psychiatr Scandinavica"},{"key":"1080_CR17","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.genhosppsych.2015.12.005","volume":"39","author":"H-J Seo","year":"2016","unstructured":"Seo H-J, Wang H-R, Jun T-Y, Woo YS, Bahk W-M. Factors related to suicidal behavior in patients with bipolar disorder: the effect of mixed features on suicidality. Gen hospital psychiatry. 2016;39:91\u201396.","journal-title":"Gen hospital psychiatry"},{"key":"1080_CR18","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1017\/S0033291713000512","volume":"44","author":"M Berlim","year":"2014","unstructured":"Berlim M, Van den Eynde F, Tovar-Perdomo S, Daskalakis Z. Response, remission and dropout rates following high-frequency repetitive transcranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials. Psychological Med. 2014;44:225.","journal-title":"Psychological Med"},{"key":"1080_CR19","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.eurpsy.2016.11.002","volume":"41","author":"S Teng","year":"2017","unstructured":"Teng S, Guo Z, Peng H, Xing G, Chen H, He B, et al. High-frequency repetitive transcranial magnetic stimulation over the left DLPFC for major depression: session-dependent efficacy: a meta-analysis. Eur Psychiatry. 2017;41:75\u201384.","journal-title":"Eur Psychiatry"},{"key":"1080_CR20","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1001\/jamapsychiatry.2016.3644","volume":"74","author":"AR Brunoni","year":"2017","unstructured":"Brunoni AR, Chaimani A, Moffa AH, Razza LB, Gattaz WF, Daskalakis ZJ, et al. Repetitive transcranial magnetic stimulation for the acute treatment of major depressive episodes: a systematic review with network meta-analysis. JAMA psychiatry. 2017;74:143\u201352.","journal-title":"JAMA psychiatry"},{"key":"1080_CR21","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.pnpbp.2019.01.014","volume":"92","author":"T Schwippel","year":"2019","unstructured":"Schwippel T, Schroeder PA, Fallgatter AJ, Plewnia C. Clinical review: The therapeutic use of theta-burst stimulation in mental disorders and tinnitus. Prog Neuro-Psychopharmacol Biol Psychiatry. 2019;92:285\u2013300.","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"1080_CR22","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1016\/S0140-6736(18)30295-2","volume":"391","author":"DM Blumberger","year":"2018","unstructured":"Blumberger DM, Vila-Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, et al. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial. Lancet. 2018;391:1683\u201392.","journal-title":"Lancet"},{"key":"1080_CR23","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3389\/fpsyt.2018.00413","volume":"9","author":"X Cao","year":"2018","unstructured":"Cao X, Deng C, Su X, Guo Y. Response and remission rates following high-frequency vs. low-frequency repetitive transcranial magnetic stimulation (rTMS) over right DLPFC for treating major depressive disorder (MDD): a meta-analysis of randomized, double-blind trials. Front psychiatry. 2018;9:413.","journal-title":"Front psychiatry"},{"key":"1080_CR24","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1016\/j.brs.2018.04.014","volume":"11","author":"C-T Li","year":"2018","unstructured":"Li C-T, Chen M-H, Juan C-H, Liu R-S, Lin W-C, Bai Y-M, et al. Effects of prefrontal theta-burst stimulation on brain function in treatment-resistant depression: a randomized sham-controlled neuroimaging study. Brain stimulation. 2018;11:1054\u201362.","journal-title":"Brain stimulation"},{"key":"1080_CR25","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1038\/s41386-018-0009-9","volume":"43","author":"PB Fitzgerald","year":"2018","unstructured":"Fitzgerald PB, Hoy KE, Elliot D, McQueen RS, Wambeek LE, Daskalakis ZJ. Accelerated repetitive transcranial magnetic stimulation in the treatment of depression. Neuropsychopharmacology 2018;43:1565\u201372.","journal-title":"Neuropsychopharmacology"},{"key":"1080_CR26","doi-asserted-by":"crossref","unstructured":"Lefaucheur J-P, Aleman A, Baeken C, Benninger DH, Brunelin J, Di Lazzaro V, et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): an update (2014\u20132018). Clinical neurophysiology. 2020;131:474-528.","DOI":"10.1016\/j.clinph.2019.11.002"},{"key":"1080_CR27","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jad.2013.12.024","volume":"157","author":"S Pallanti","year":"2014","unstructured":"Pallanti S, Grassi G, Antonini S, Quercioli L, Salvadori E, Hollander E. rTMS in resistant mixed states: an exploratory study. J Affect Disord. 2014;157:66\u201371.","journal-title":"J Affect Disord"},{"key":"1080_CR28","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.brs.2010.03.001","volume":"4","author":"D Zeeuws","year":"2011","unstructured":"Zeeuws D, De Rycker K, De Raedt R, De Beyne M, Baeken C, Vanderbruggen N. Intensive high-frequency repetitive transcranial magnetic stimulation treatment in an electroconvulsive shock therapy-resistant bipolar I patient with mixed episode. Brain stimulation. 2011;4:46\u201349.","journal-title":"Brain stimulation"},{"key":"1080_CR29","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.jad.2008.12.020","volume":"117","author":"SK Praharaj","year":"2009","unstructured":"Praharaj SK, Ram D, Arora M. Efficacy of high frequency (rapid) suprathreshold repetitive transcranial magnetic stimulation of right prefrontal cortex in bipolar mania: a randomized sham controlled study. J Affect Disord. 2009;117:146\u201350.","journal-title":"J Affect Disord"},{"key":"1080_CR30","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.psychres.2004.05.019","volume":"128","author":"G Saba","year":"2004","unstructured":"Saba G, Rocamora JF, Kalalou K, Benadhira R, Plaze M, Lipski H, et al. Repetitive transcranial magnetic stimulation as an add-on therapy in the treatment of mania: a case series of eight patients. Psychiatry Res. 2004;128:199\u2013202.","journal-title":"Psychiatry Res"},{"key":"1080_CR31","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0165-0327(02)00308-7","volume":"78","author":"N Michael","year":"2004","unstructured":"Michael N, Erfurth A. Treatment of bipolar mania with right prefrontal rapid transcranial magnetic stimulation. J Affect Disord. 2004;78:253\u201357.","journal-title":"J Affect Disord"},{"key":"1080_CR32","doi-asserted-by":"publisher","first-page":"650","DOI":"10.2471\/BLT.08.050955","volume":"86","author":"JR Williams","year":"2008","unstructured":"Williams JR. The Declaration of Helsinki and public health. Bull World Health Organ. 2008;86:650\u201352.","journal-title":"Bull World Health Organ"},{"key":"1080_CR33","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1590\/S1516-44462001000300008","volume":"23","author":"C Del-Ben","year":"2010","unstructured":"Del-Ben C, Vilela J, de S, Crippa JA, Hallak JEC, Labate CM, et al. Confiabilidade de\u201d Entrevista Cl\u0131nica Estruturada para o DSM-IV\u2013Versao Cl\u0131nica\u201d traduzida para o portugu\u00eas.\/Reliability of the Structured Clinical Interview for DSM-IV\u2014Clinical Version translated into Portuguese. Rev Bras Psiquiatr. 2010;23:156\u201359.","journal-title":"Rev Bras Psiquiatr"},{"key":"1080_CR34","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/S0165-0327(01)00451-7","volume":"72","author":"C Hawley","year":"2002","unstructured":"Hawley C, Gale T, Sivakumaran T, group HNR. Defining remission by cut off score on the MADRS: selecting the optimal value. J Affect Disord. 2002;72:177\u201384.","journal-title":"J Affect Disord"},{"key":"1080_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12888-016-0823-8","volume":"16","author":"LS Duarte-Guerra","year":"2016","unstructured":"Duarte-Guerra LS, Gorenstein C, Paiva-Medeiros PF, Santo MA, Neto FL, Wang Y-P. Clinical utility of the Montgomery-\u00c5sberg Depression Rating Scale for the detection of depression among bariatric surgery candidates. BMC psychiatry. 2016;16:1\u20138.","journal-title":"BMC psychiatry"},{"key":"1080_CR36","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1590\/S0100-879X2005000900019","volume":"38","author":"J Vilela","year":"2005","unstructured":"Vilela J, Crippa J, Del-Ben C, Loureiro S. Reliability and validity of a Portuguese version of the Young Mania Rating Scale. Braz J Med Biol Res. 2005;38:1429\u201339.","journal-title":"Braz J Med Biol Res"},{"key":"1080_CR37","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1176\/appi.ajp.2012.12030301","volume":"170","author":"AC Swann","year":"2013","unstructured":"Swann AC, Lafer B, Perugi G, Frye MA, Bauer M, Bahk W-M, et al. Bipolar mixed states: an international society for bipolar disorders task force report of symptom structure, course of illness, and diagnosis. Am J Psychiatry. 2013;170:31\u201342.","journal-title":"Am J Psychiatry"},{"key":"1080_CR38","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.jad.2014.04.003","volume":"164","author":"M Tohen","year":"2014","unstructured":"Tohen M, Kanba S, McIntyre RS, Fujikoshi S, Katagiri H. Efficacy of olanzapine monotherapy in the treatment of bipolar depression with mixed features. J Affect Disord. 2014;164:57\u201362.","journal-title":"J Affect Disord"},{"key":"1080_CR39","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.jad.2012.05.036","volume":"143","author":"J-M Azorin","year":"2012","unstructured":"Azorin J-M, Kaladjian A, Adida M, Fakra E, Belzeaux R, Hantouche E, et al. Self-assessment and characteristics of mixed depression in the French national EPIDEP study. J Affect Disord. 2012;143:109\u201317.","journal-title":"J Affect Disord"},{"key":"1080_CR40","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1177\/0706743716659417","volume":"61","author":"SH Kennedy","year":"2016","unstructured":"Kennedy SH, Lam RW, McIntyre RS, Tourjman SV, Bhat V, Blier P, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 3. Pharmacological treatments. Can J Psychiatry. 2016;61:540\u201360.","journal-title":"Can J Psychiatry"},{"key":"1080_CR41","doi-asserted-by":"publisher","first-page":"435","DOI":"10.3389\/fpsyt.2020.00435","volume":"11","author":"DF Tavares","year":"2020","unstructured":"Tavares DF, Dos Santos CGR, Valiengo L, Klein I, Borrione L, Forte PM, et al. Efficacy, safety, and tolerability of theta-burst stimulation in mixed depression: design, rationale, and objectives of a randomized, double-blinded, sham-controlled trial. Front psychiatry. 2020;11:435.","journal-title":"Front psychiatry"},{"key":"1080_CR42","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1590\/1516-4446-2017-0018","volume":"41","author":"AR Brunoni","year":"2019","unstructured":"Brunoni AR, Sampaio-Junior B, Moffa AH, Apar\u00edcio LV, Gordon P, Klein I, et al. Noninvasive brain stimulation in psychiatric disorders: a primer. Braz J Psychiatry. 2019;41:70\u201381.","journal-title":"Braz J Psychiatry"},{"key":"1080_CR43","doi-asserted-by":"publisher","first-page":"2088","DOI":"10.1093\/brain\/awu109","volume":"137","author":"C-T Li","year":"2014","unstructured":"Li C-T, Chen M-H, Juan C-H, Huang H-H, Chen L-F, Hsieh J-C, et al. Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain 2014;137:2088\u201398.","journal-title":"Brain"},{"key":"1080_CR44","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1016\/S0140-6736(18)30295-2","volume":"391","author":"DM Blumberger","year":"2018","unstructured":"Blumberger DM, Vila-Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, et al. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial. Lancet 2018;391:1683\u201392.","journal-title":"Lancet"},{"key":"1080_CR45","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1017\/S1461145710000027","volume":"13","author":"AV Chistyakov","year":"2010","unstructured":"Chistyakov AV, Rubicsek O, Kaplan B, Zaaroor M, Klein E. Safety, tolerability and preliminary evidence for antidepressant efficacy of theta-burst transcranial magnetic stimulation in patients with major depression. Int J Neuropsychopharmacol. 2010;13:387\u201393.","journal-title":"Int J Neuropsychopharmacol"},{"key":"1080_CR46","doi-asserted-by":"publisher","first-page":"6849","DOI":"10.1523\/JNEUROSCI.4993-13.2014","volume":"34","author":"C Nettekoven","year":"2014","unstructured":"Nettekoven C, Volz LJ, Kutscha M, Pool EM, Rehme AK, Eickhoff SB, et al. Dose-dependent effects of theta burst rTMS on cortical excitability and resting-state connectivity of the human motor system. J Neurosci. 2014;34:6849\u201359.","journal-title":"J Neurosci"},{"key":"1080_CR47","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jad.2013.12.025","volume":"156","author":"C Plewnia","year":"2014","unstructured":"Plewnia C, Pasqualetti P, Gro\u00dfe S, Schlipf S, Wasserka B, Zwissler B, et al. Treatment of major depression with bilateral theta burst stimulation: a randomized controlled pilot trial. J Affect Disord. 2014;156:219\u201323.","journal-title":"J Affect Disord"},{"key":"1080_CR48","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/j.biopsych.2019.07.031","volume":"87","author":"CT Li","year":"2020","unstructured":"Li CT, Cheng CM, Chen MH, Juan CH, Tu PC, Bai YM, et al. Antidepressant efficacy of prolonged intermittent theta burst stimulation monotherapy for recurrent depression and comparison of methods for coil positioning: a randomized, double-blind, sham-controlled study. Biol Psychiatry. 2020;87:443\u201350.","journal-title":"Biol Psychiatry"},{"key":"1080_CR49","doi-asserted-by":"publisher","first-page":"2088","DOI":"10.1093\/brain\/awu109","volume":"137","author":"CT Li","year":"2014","unstructured":"Li CT, Chen MH, Juan CH, Huang HH, Chen LF, Hsieh JC, et al. Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain 2014;137:2088\u201398.","journal-title":"Brain"},{"key":"1080_CR50","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.jad.2014.08.035","volume":"170","author":"AV Chistyakov","year":"2015","unstructured":"Chistyakov AV, Kreinin B, Marmor S, Kaplan B, Khatib A, Darawsheh N, et al. Preliminary assessment of the therapeutic efficacy of continuous theta-burst magnetic stimulation (cTBS) in major depression: a double-blind sham-controlled study. J Affect Disord. 2015;170:225\u20139.","journal-title":"J Affect Disord"},{"key":"1080_CR51","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1001\/archgenpsychiatry.2010.46","volume":"67","author":"MS George","year":"2010","unstructured":"George MS, Lisanby SH, Avery D, McDonald WM, Durkalski V, Pavlicova M, et al. Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial. Arch Gen Psychiatry. 2010;67:507\u201316.","journal-title":"Arch Gen Psychiatry"},{"key":"1080_CR52","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1002\/wps.20199","volume":"14","author":"Y Levkovitz","year":"2015","unstructured":"Levkovitz Y, Isserles M, Padberg F, Lisanby SH, Bystritsky A, Xia G, et al. Efficacy and safety of deep transcranial magnetic stimulation for major depression: a prospective multicenter randomized controlled trial. World Psychiatry. 2015;14:64\u201373.","journal-title":"World Psychiatry"},{"key":"1080_CR53","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1097\/WNP.0b013e318205135f","volume":"28","author":"L Oberman","year":"2011","unstructured":"Oberman L, Edwards D, Eldaief M, Pascual-Leone A. Safety of theta burst transcranial magnetic stimulation: a systematic review of the literature. J Clin Neurophysiol. 2011;28:67.","journal-title":"J Clin Neurophysiol"},{"key":"1080_CR54","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1590\/0047-2085000000036","volume":"63","author":"M\u00c1 Freire","year":"2014","unstructured":"Freire M\u00c1, Figueiredo VLMD, Gomide A, Jansen K, Silva RAD, Magalh\u00e3es PVDS, et al. Escala Hamilton: estudo das caracter\u00edsticas psicom\u00e9tricas em uma amostra do sul do Brasil. J Brasileiro de Psiquiatria. 2014;63:281\u201389.","journal-title":"J Brasileiro de Psiquiatria"},{"key":"1080_CR55","doi-asserted-by":"crossref","unstructured":"Guy W. ECDEU Assessment Manual for Psychopharmacology-Revised. Rockville, MD: National Institute of Mental Health. Psychopharmacol Res Branch. 1976:217\u201322.","DOI":"10.1037\/e591322011-001"},{"key":"1080_CR56","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1192\/bjp.166.5.654","volume":"166","author":"SH Jones","year":"1995","unstructured":"Jones SH, Thornicroft G, Coffey M, Dunn G. A brief mental health outcome scale. Br J Psychiatry. 1995;166:654\u201359.","journal-title":"Br J Psychiatry"},{"key":"1080_CR57","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1590\/S0034-89102000000200012","volume":"34","author":"M Fleck","year":"2000","unstructured":"Fleck M, Louzada S, Xavier M, Chachamovich E, Vieira G, Santos L, et al. Aplica\u00e7\u00e3o da vers\u00e3o em portugu\u00eas do instrumento abreviado de avalia\u00e7\u00e3o da qualidade de vida\u201d WHOQOL-bref\u201d. Rev de sa\u00fade p\u00fablica. 2000;34:178\u201383.","journal-title":"Rev de sa\u00fade p\u00fablica"},{"key":"1080_CR58","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1590\/S0047-20852010000200004","volume":"59","author":"LF Malloy-Diniz","year":"2010","unstructured":"Malloy-Diniz LF, Mattos P, Leite WB, Abreu N, Coutinho G, Paula JJD, et al. Tradu\u00e7\u00e3o e adapta\u00e7\u00e3o cultural da Barratt Impulsiveness Scale (BIS-11) para aplica\u00e7\u00e3o em adultos brasileiros. J Brasileiro de Psiquiatria. 2010;59:99\u2013105.","journal-title":"J Brasileiro de Psiquiatria"},{"key":"1080_CR59","doi-asserted-by":"crossref","unstructured":"Bates D, M\u00e4chler M, Bolker B, Walker S Fitting linear mixed-effects models using lme4. arXiv preprint arXiv:14065823. 2014.","DOI":"10.18637\/jss.v067.i01"},{"key":"1080_CR60","doi-asserted-by":"crossref","unstructured":"Buuren SV, Groothuis-Oudshoorn K. mice: Multivariate imputation by chained equations in R. J of statistical software. 2010;45:1\u201368.","DOI":"10.18637\/jss.v045.i03"},{"key":"1080_CR61","first-page":"3","volume":"1","author":"R Lenth","year":"2018","unstructured":"Lenth R, Singmann H, Love J, Buerkner P, Herve M. Emmeans: Estimated marginal means, aka least-squares means. R package version. 2018;1:3.","journal-title":"R package version"},{"key":"1080_CR62","unstructured":"Team RC (Vienna, Austria: R Foundation for Statistical Computing. Retrieved from, 2017)."},{"key":"1080_CR63","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1176\/appi.ajp.2015.15060770","volume":"173","author":"T Suppes","year":"2016","unstructured":"Suppes T, Silva R, Cucchiaro J, Mao Y, Targum S, Streicher C, et al. Lurasidone for the Treatment of Major Depressive Disorder With Mixed Features: A Randomized, Double-Blind, Placebo-Controlled Study. Am J Psychiatry. 2016;173:400\u20137.","journal-title":"Am J Psychiatry"},{"key":"1080_CR64","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1001\/archneur.1982.00510160016003","volume":"39","author":"HA Sackeim","year":"1982","unstructured":"Sackeim HA, Greenberg MS, Weiman AL, Gur RC, Hungerbuhler JP, Geschwind N. Hemispheric asymmetry in the expression of positive and negative emotions. Neurologic Evid Arch Neurol. 1982;39:210\u20138.","journal-title":"Neurologic Evid Arch Neurol"},{"key":"1080_CR65","doi-asserted-by":"publisher","first-page":"S162","DOI":"10.1016\/S0013-7006(13)70116-7","volume":"39","author":"A Kaladjian","year":"2013","unstructured":"Kaladjian A, Belzeaux R, Micoulaud-Franchi JA, Cermolacce M, Fakra E, Azorin JM. [Mixed states and neuroimaging]. Encephale 2013;39:S162\u20136.","journal-title":"Encephale"},{"key":"1080_CR66","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1159\/000358808","volume":"83","author":"G Sani","year":"2014","unstructured":"Sani G, Napoletano F, V\u00f6hringer PA, Sullivan M, Simonetti A, Koukopoulos A, et al. Mixed depression: clinical features and predictors of its onset associated with antidepressant use. Psychother Psychosom. 2014;83:213\u201321.","journal-title":"Psychother Psychosom"},{"key":"1080_CR67","doi-asserted-by":"publisher","first-page":"241","DOI":"10.3390\/ijms17020241","volume":"17","author":"M Fornaro","year":"2016","unstructured":"Fornaro M, Stubbs B, De Berardis D, Perna G, Valchera A, Veronese N, et al. Atypical antipsychotics in the treatment of acute bipolar depression with mixed features: a systematic review and exploratory meta-analysis of placebo-controlled clinical trials. Int J Mol Sci. 2016;17:241.","journal-title":"Int J Mol Sci"},{"key":"1080_CR68","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.psc.2019.10.006","volume":"43","author":"I Pacchiarotti","year":"2020","unstructured":"Pacchiarotti I, Kotzalidis GD, Murru A, Mazzarini L, Rapinesi C, Valent\u00ed M, et al. Mixed features in depression: the unmet needs of diagnostic and statistical manual of mental disorders fifth edition. Psychiatr Clin North Am. 2020;43:59\u201368.","journal-title":"Psychiatr Clin North Am"},{"key":"1080_CR69","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1017\/S1092852917000013","volume":"22","author":"A Cuomo","year":"2017","unstructured":"Cuomo A, Nikolova VL, Yalin N, Arnone D, Fagiolini A, Young AH. Pharmacological treatment of mixed states. CNS Spectr. 2017;22:186\u201395.","journal-title":"CNS Spectr"},{"key":"1080_CR70","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1017\/S1092852917000256","volume":"22","author":"T Suppes","year":"2017","unstructured":"Suppes T, Ostacher M. Mixed features in major depressive disorder: diagnoses and treatments. CNS Spectr. 2017;22:155\u201360.","journal-title":"CNS Spectr"},{"key":"1080_CR71","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1080\/15622975.2017.1384850","volume":"19","author":"H Grunze","year":"2018","unstructured":"Grunze H, Vieta E, Goodwin GM, Bowden C, Licht RW, Azorin JM, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: acute and long-term treatment of mixed states in bipolar disorder. World J Biol Psychiatry. 2018;19:2\u201358.","journal-title":"World J Biol Psychiatry"},{"key":"1080_CR72","doi-asserted-by":"publisher","first-page":"e008341","DOI":"10.1136\/bmjopen-2015-008341","volume":"5","author":"R Patel","year":"2015","unstructured":"Patel R, Reiss P, Shetty H, Broadbent M, Stewart R, McGuire P, et al. Do antidepressants increase the risk of mania and bipolar disorder in people with depression? A retrospective electronic case register cohort study. BMJ Open. 2015;5:e008341.","journal-title":"BMJ Open"},{"key":"1080_CR73","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1017\/neu.2015.52","volume":"28","author":"L Bj\u00f8rklund","year":"2016","unstructured":"Bj\u00f8rklund L, Horsdal HT, Mors O, \u00d8stergaard SD, Gasse C. Trends in the psychopharmacological treatment of bipolar disorder: a nationwide register-based study. Acta Neuropsychiatr. 2016;28:75\u201384.","journal-title":"Acta Neuropsychiatr"},{"key":"1080_CR74","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1017\/S1092852917000165","volume":"22","author":"SM Stahl","year":"2017","unstructured":"Stahl SM, Morrissette DA, Faedda G, Fava M, Goldberg JF, Keck PE, et al. Guidelines for the recognition and management of mixed depression. CNS Spectr. 2017;22:203\u201319.","journal-title":"CNS Spectr"},{"key":"1080_CR75","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1007\/s11126-020-09822-6","volume":"91","author":"MMK Tee","year":"2020","unstructured":"Tee MMK, Au CH. A systematic review and meta-analysis of randomized sham-controlled trials of repetitive transcranial magnetic stimulation for bipolar disorder. Psychiatr Q. 2020;91:1225\u201347.","journal-title":"Psychiatr Q"},{"key":"1080_CR76","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0165-0327(01)00444-X","volume":"67","author":"F Benazzi","year":"2001","unstructured":"Benazzi F, Akiskal HS. Delineating bipolar II mixed states in the Ravenna-San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes. J Affect Disord. 2001;67:115\u201322.","journal-title":"J Affect Disord"},{"key":"1080_CR77","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.jad.2004.12.004","volume":"85","author":"HS Akiskal","year":"2005","unstructured":"Akiskal HS, Benazzi F, Perugi G, Rihmer Z. Agitated \u201cunipolar\u201d depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy. J Affect Disord. 2005;85:245\u201358.","journal-title":"J Affect Disord"},{"key":"1080_CR78","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1001\/archgenpsychiatry.2011.87","volume":"68","author":"J Angst","year":"2011","unstructured":"Angst J, Azorin JM, Bowden CL, Perugi G, Vieta E, Gamma A, et al. Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. Arch Gen Psychiatry. 2011;68:791\u20138.","journal-title":"Arch Gen Psychiatry"},{"key":"1080_CR79","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.jad.2011.12.046","volume":"138","author":"LL Judd","year":"2012","unstructured":"Judd LL, Schettler PJ, Akiskal H, Coryell W, Fawcett J, Fiedorowicz JG, et al. Prevalence and clinical significance of subsyndromal manic symptoms, including irritability and psychomotor agitation, during bipolar major depressive episodes. J Affect Disord. 2012;138:440\u20138.","journal-title":"J Affect Disord"},{"key":"1080_CR80","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.jad.2011.11.024","volume":"136","author":"CU Pae","year":"2012","unstructured":"Pae CU, V\u00f6hringer PA, Holtzman NS, Thommi SB, Patkar A, Gilmer W, et al. Mixed depression: a study of its phenomenology and relation to treatment response. J Affect Disord. 2012;136:1059\u201361.","journal-title":"J Affect Disord"},{"key":"1080_CR81","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1017\/S0033291713000512","volume":"44","author":"MT Berlim","year":"2014","unstructured":"Berlim MT, van den Eynde F, Tovar-Perdomo S, Daskalakis ZJ. Response remission and dropout rates following high-frequency repetitive transcranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials. Psychol Med. 2014;44:225\u201339.","journal-title":"Psychol Med"},{"key":"1080_CR82","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1590\/1414-431x20144270","volume":"48","author":"YQ Zhang","year":"2015","unstructured":"Zhang YQ, Zhu D, Zhou XY, Liu YY, Qin B, Ren GP, et al. Bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis of randomized controlled trials. Braz J Med Biol Res. 2015;48:198\u2013206.","journal-title":"Braz J Med Biol Res"},{"key":"1080_CR83","doi-asserted-by":"publisher","first-page":"l1079","DOI":"10.1136\/bmj.l1079","volume":"364","author":"J Mutz","year":"2019","unstructured":"Mutz J, Vipulananthan V, Carter B, Hurlemann R, Fu CHY, Young AH. Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis. Bmj 2019;364:l1079.","journal-title":"Bmj"},{"key":"1080_CR84","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.neubiorev.2018.05.015","volume":"92","author":"J Mutz","year":"2018","unstructured":"Mutz J, Edgcumbe DR, Brunoni AR, Fu CHY. Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: A systematic review and meta-analysis of randomised sham-controlled trials. Neurosci Biobehav Rev. 2018;92:291\u2013303.","journal-title":"Neurosci Biobehav Rev"},{"key":"1080_CR85","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/wps.20300","volume":"15","author":"A McGirr","year":"2016","unstructured":"McGirr A, Karmani S, Arsappa R, Berlim MT, Thirthalli J, Muralidharan K, et al. Clinical efficacy and safety of repetitive transcranial magnetic stimulation in acute bipolar depression. World Psychiatry. 2016;15:85\u20136.","journal-title":"World Psychiatry"},{"key":"1080_CR86","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/j.jad.2020.10.013","volume":"279","author":"TD Nguyen","year":"2021","unstructured":"Nguyen TD, Hieronymus F, Lorentzen R, McGirr A, \u00d8stergaard SD. The efficacy of repetitive transcranial magnetic stimulation (rTMS) for bipolar depression: A systematic review and meta-analysis. J Affect Disord. 2021;279:250\u201355.","journal-title":"J Affect Disord"},{"key":"1080_CR87","doi-asserted-by":"publisher","first-page":"2593","DOI":"10.1038\/npp.2017.26","volume":"42","author":"DF Tavares","year":"2017","unstructured":"Tavares DF, Myczkowski ML, Alberto RL, Valiengo L, Rios RM, Gordon P, et al. Treatment of bipolar depression with deep TMS: results from a double-blind, randomized, parallel group, sham-controlled clinical trial. Neuropsychopharmacology 2017;42:2593\u2013601.","journal-title":"Neuropsychopharmacology"},{"key":"1080_CR88","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.neucli.2019.10.002","volume":"49","author":"S Bulteau","year":"2019","unstructured":"Bulteau S, Beynel L, Marendaz C, Dall\u2019Igna G, Per\u00e9 M, Harquel S, et al. Twice-daily neuronavigated intermittent theta burst stimulation for bipolar depression: A Randomized Sham-Controlled Pilot Study. Neurophysiol Clin. 2019;49:371\u201375.","journal-title":"Neurophysiol Clin"},{"key":"1080_CR89","doi-asserted-by":"publisher","first-page":"1961","DOI":"10.1016\/j.clinph.2017.07.395","volume":"128","author":"R Rostami","year":"2017","unstructured":"Rostami R, Kazemi R, Nitsche MA, Gholipour F, Salehinejad MA. Clinical and demographic predictors of response to rTMS treatment in unipolar and bipolar depressive disorders. Clin Neurophysiol. 2017;128:1961\u201370.","journal-title":"Clin Neurophysiol"},{"key":"1080_CR90","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1177\/0706743720950938","volume":"66","author":"YB Yang","year":"2021","unstructured":"Yang YB, Chan P, Rayani K, McGirr A. Comparative effectiveness of repetitive transcranial magnetic stimulation in unipolar and bipolar depression. Can J Psychiatry. 2021;66:313\u201315.","journal-title":"Can J Psychiatry"},{"key":"1080_CR91","doi-asserted-by":"publisher","first-page":"e210963","DOI":"10.1001\/jamanetworkopen.2021.0963","volume":"4","author":"A McGirr","year":"2021","unstructured":"McGirr A, Vila-Rodriguez F, Cole J, Torres IJ, Arumugham SS, Keramatian K, et al. Efficacy of active vs sham intermittent theta burst transcranial magnetic stimulation for patients with bipolar depression: a randomized clinical trial. JAMA Netw Open. 2021;4:e210963.","journal-title":"JAMA Netw Open"},{"key":"1080_CR92","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1176\/ajp.155.11.1608","volume":"155","author":"N Grisaru","year":"1998","unstructured":"Grisaru N, Chudakov B, Yaroslavsky Y, Belmaker RH. Transcranial magnetic stimulation in mania: a controlled study. Am J Psychiatry. 1998;155:1608\u201310.","journal-title":"Am J Psychiatry"},{"key":"1080_CR93","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1034\/j.1399-5618.2003.00003.x","volume":"5","author":"A Kaptsan","year":"2003","unstructured":"Kaptsan A, Yaroslavsky Y, Applebaum J, Belmaker RH, Grisaru N. Right prefrontal TMS versus sham treatment of mania: a controlled study. Bipolar Disord. 2003;5:36\u20139.","journal-title":"Bipolar Disord"},{"key":"1080_CR94","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0165-0327(02)00308-7","volume":"78","author":"N Michael","year":"2004","unstructured":"Michael N, Erfurth A. Treatment of bipolar mania with right prefrontal rapid transcranial magnetic stimulation. J Affect Disord. 2004;78:253\u20137.","journal-title":"J Affect Disord"},{"key":"1080_CR95","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.psychres.2004.05.019","volume":"128","author":"G Saba","year":"2004","unstructured":"Saba G, Rocamora JF, Kalalou K, Benadhira R, Plaze M, Lipski H, et al. Repetitive transcranial magnetic stimulation as an add-on therapy in the treatment of mania: a case series of eight patients. Psychiatry Res. 2004;128:199\u2013202.","journal-title":"Psychiatry Res"},{"key":"1080_CR96","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.jad.2008.12.020","volume":"117","author":"SK Praharaj","year":"2009","unstructured":"Praharaj SK, Ram D, Arora M. Efficacy of high frequency (rapid) suprathreshold repetitive transcranial magnetic stimulation of right prefrontal cortex in bipolar mania: a randomized sham controlled study. J Affect Disord. 2009;117:146\u201350.","journal-title":"J Affect Disord"},{"key":"1080_CR97","doi-asserted-by":"publisher","first-page":"245","DOI":"10.9758\/cpn.2015.13.3.245","volume":"13","author":"V Pathak","year":"2015","unstructured":"Pathak V, Sinha VK, Praharaj SK. Efficacy of adjunctive high frequency repetitive transcranial magnetic stimulation of right prefrontal cortex in adolescent mania: a randomized sham-controlled study. Clin Psychopharmacol Neurosci. 2015;13:245\u20139.","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"1080_CR98","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/j.brs.2015.05.008","volume":"8","author":"A Mir-Moghtadaei","year":"2015","unstructured":"Mir-Moghtadaei A, Caballero R, Fried P, Fox MD, Lee K, Giacobbe P, et al. Concordance between BeamF3 and MRI-neuronavigated target sites for repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex. Brain Stimul. 2015;8:965\u201373.","journal-title":"Brain Stimul"},{"key":"1080_CR99","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3109\/15622975.2014.964768","volume":"16","author":"J Prasser","year":"2015","unstructured":"Prasser J, Schecklmann M, Poeppl TB, Frank E, Kreuzer PM, Hajak G, et al. Bilateral prefrontal rTMS and theta burst TMS as an add-on treatment for depression: a randomized placebo controlled trial. World J Biol Psychiatry. 2015;16:57\u201365.","journal-title":"World J Biol Psychiatry"},{"key":"1080_CR100","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.jad.2016.04.015","volume":"200","author":"R Duprat","year":"2016","unstructured":"Duprat R, Desmyter S, Rudi de R, van Heeringen K, Van den Abbeele D, Tandt H, et al. Accelerated intermittent theta burst stimulation treatment in medication-resistant major depression: A fast road to remission? J Affect Disord. 2016;200:6\u201314.","journal-title":"J Affect Disord"}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41386-021-01080-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41386-021-01080-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41386-021-01080-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T15:04:12Z","timestamp":1675523052000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41386-021-01080-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,30]]},"references-count":100,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1080"],"URL":"https:\/\/doi.org\/10.1038\/s41386-021-01080-9","relation":{},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,30]]},"assertion":[{"value":"16 April 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"DFT worked as a speaker and produced scientific source during the last two years for the following pharmaceutical companies: Crist\u00e1lia, Ach\u00e9, Torrent, Abbott, Lundbeck. ARB reports grants from SaoPaulo Research State Foundation (FAPESP, 2017\/50223-6, 2018\/10861-7, 2019\/06009-6), Newton Advanced Fellowship (12\/1010), Brazilian National Council of Scientific Development Productivity Support (PQ-1B) and University of Sao Paulo Medical School Productivity Support (PIPA-A).\u00a0. RAM reports grants from Sao Paulo Research State Foundation (FAPESP) and from the National Research Council (CNPq). Other authors declare no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}