{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:43:44Z","timestamp":1790905424466,"version":"4.1.0"},"reference-count":87,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T00:00:00Z","timestamp":1711152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T00:00:00Z","timestamp":1711152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-189943"],"award-info":[{"award-number":["PJT-189943"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol."],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1038\/s41386-024-01853-y","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T15:01:56Z","timestamp":1711206116000},"page":"1171-1182","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system"],"prefix":"10.1038","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9035-5600","authenticated-orcid":false,"given":"Tsun Hay Jason","family":"Ng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5511-2638","authenticated-orcid":false,"given":"Mohammed H.","family":"Sarikahya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Hudson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna J.","family":"Szkudlarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enzo","family":"P\u00e9rez-Valenzuela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taygun C.","family":"Uzuneser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Proud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Gummerson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miray","family":"Youssef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuralay","family":"Zhaksylyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9938-0993","authenticated-orcid":false,"given":"Marieka V.","family":"DeVuono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaochao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6933-2941","authenticated-orcid":false,"given":"Ken K.-C.","family":"Yeung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter J.","family":"Rushlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven R.","family":"Laviolette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"key":"1853_CR1","unstructured":"National Center for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health. The Health Consequences of Smoking\u201450 Years of Progress: A Report of the Surgeon General. Atlanta (GA): Centers for Disease Control and Prevention (US); 2014."},{"key":"1853_CR2","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.15585\/mmwr.mm6745a5","volume":"67","author":"KA Cullen","year":"2018","unstructured":"Cullen KA, Ambrose BK, Gentzke AS, Apelberg BJ, Jamal A, King BA. Notes from the Field: Use of Electronic Cigarettes and Any Tobacco Product Among Middle and High School Students - United States, 2011-2018. MMWR Morb Mortal Wkly Rep. 2018;67:1276\u20137.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"1853_CR3","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/S0149-7634(00)00014-2","volume":"24","author":"LP Spear","year":"2000","unstructured":"Spear LP. The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev. 2000;24:417\u201363.","journal-title":"Neurosci Biobehav Rev"},{"key":"1853_CR4","first-page":"449","volume":"9","author":"M Arain","year":"2013","unstructured":"Arain M, Haque M, Johal L, Mathur P, Nel W, Rais A, et al. Maturation of the adolescent brain. Neuropsychiatr Dis Treat. 2013;9:449\u201361.","journal-title":"Neuropsychiatr Dis Treat"},{"key":"1853_CR5","doi-asserted-by":"publisher","first-page":"3397","DOI":"10.1113\/JP270492","volume":"593","author":"M Yuan","year":"2015","unstructured":"Yuan M, Cross SJ, Loughlin SE, Leslie FM. Nicotine and the adolescent brain. J Physiol. 2015;593:3397\u2013412.","journal-title":"J Physiol"},{"key":"1853_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2020.108411","volume":"184","author":"SR Laviolette","year":"2020","unstructured":"Laviolette SR. Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders. Neuropharmacology. 2020;184:108411.","journal-title":"Neuropharmacology"},{"key":"1853_CR7","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1192\/bjp.bp.109.065912","volume":"196","author":"JM Boden","year":"2010","unstructured":"Boden JM, Fergusson DM, Horwood LJ. Cigarette smoking and depression: tests of causal linkages using a longitudinal birth cohort. Br J Psychiatry J Ment Sci. 2010;196:440\u20136.","journal-title":"Br J Psychiatry J Ment Sci"},{"key":"1853_CR8","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.2105\/AJPH.2012.300911","volume":"103","author":"R Mojtabai","year":"2013","unstructured":"Mojtabai R, Crum RM. Cigarette smoking and onset of mood and anxiety disorders. Am J Public Health. 2013;103:1656\u201365.","journal-title":"Am J Public Health"},{"key":"1853_CR9","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1002\/brb3.137","volume":"3","author":"S Moylan","year":"2013","unstructured":"Moylan S, Jacka FN, Pasco JA, Berk M. How cigarette smoking may increase the risk of anxiety symptoms and anxiety disorders: a critical review of biological pathways. Brain Behav. 2013;3:302\u201326.","journal-title":"Brain Behav"},{"key":"1853_CR10","doi-asserted-by":"publisher","first-page":"3140","DOI":"10.1093\/cercor\/bhy179","volume":"29","author":"CLM Jobson","year":"2019","unstructured":"Jobson CLM, Renard J, Szkudlarek H, Rosen LG, Pereira B, Wright DJ, et al. Adolescent Nicotine Exposure Induces Dysregulation of Mesocorticolimbic Activity States and Depressive and Anxiety-like Prefrontal Cortical Molecular Phenotypes Persisting into Adulthood. Cereb Cortex. 2019;29:3140\u201353.","journal-title":"Cereb Cortex"},{"key":"1853_CR11","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12891","volume":"26","author":"R Hudson","year":"2021","unstructured":"Hudson R, Green M, Wright DJ, Renard J, Jobson CEL, Jung T, et al. Adolescent nicotine induces depressive and anxiogenic effects through ERK 1-2 and Akt-GSK-3 pathways and neuronal dysregulation in the nucleus accumbens. Addict Biol. 2021;26:e12891.","journal-title":"Addict Biol"},{"key":"1853_CR12","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1038\/nrn3119","volume":"12","author":"RZ Goldstein","year":"2011","unstructured":"Goldstein RZ, Volkow ND. Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat Rev Neurosci. 2011;12:652\u201369.","journal-title":"Nat Rev Neurosci"},{"key":"1853_CR13","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1007\/s00213-015-4152-2","volume":"233","author":"MM Sweitzer","year":"2016","unstructured":"Sweitzer MM, Geier CF, Denlinger R, Forbes EE, Raiff BR, Dallery J, et al. Blunted striatal response to monetary reward anticipation during smoking abstinence predicts lapse during a contingency-managed quit attempt. Psychopharmacology. 2016;233:751\u201360.","journal-title":"Psychopharmacology"},{"key":"1853_CR14","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1002\/hbm.23153","volume":"37","author":"K Yuan","year":"2016","unstructured":"Yuan K, Yu D, Bi Y, Li Y, Guan Y, Liu J, et al. The implication of frontostriatal circuits in young smokers: A resting-state study. Hum Brain Mapp. 2016;37:2013\u201326.","journal-title":"Hum Brain Mapp"},{"key":"1853_CR15","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/npp.2008.96","volume":"34","author":"DS Counotte","year":"2009","unstructured":"Counotte DS, Spijker S, Van de Burgwal LH, Hogenboom F, Schoffelmeer ANM, De Vries TJ, et al. Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats. Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol. 2009;34:299\u2013306.","journal-title":"Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol"},{"key":"1853_CR16","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1126\/science.1120972","volume":"311","author":"O Berton","year":"2006","unstructured":"Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, et al. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science. 2006;311:864\u20138.","journal-title":"Science"},{"key":"1853_CR17","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.biopsych.2006.03.021","volume":"61","author":"LM Monteggia","year":"2007","unstructured":"Monteggia LM, Luikart B, Barrot M, Theobold D, Malkovska I, Nef S, et al. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry. 2007;61:187\u201397.","journal-title":"Biol Psychiatry"},{"key":"1853_CR18","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.semcdb.2009.01.007","volume":"20","author":"HD Mansvelder","year":"2009","unstructured":"Mansvelder HD, Mertz M, Role LW. Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits. Semin Cell Dev Biol. 2009;20:432\u201340.","journal-title":"Semin Cell Dev Biol"},{"key":"1853_CR19","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.neuropharm.2013.04.048","volume":"72","author":"L-L Bi","year":"2013","unstructured":"Bi L-L, Wang J, Luo Z-Y, Chen S-P, Geng F, Chen Y, et al. Enhanced excitability in the infralimbic cortex produces anxiety-like behaviors. Neuropharmacology. 2013;72:148\u201356.","journal-title":"Neuropharmacology"},{"key":"1853_CR20","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.pnpbp.2012.10.002","volume":"40","author":"JW Fernandez","year":"2013","unstructured":"Fernandez JW, Grizzell JA, Wecker L. The role of estrogen receptor \u03b2 and nicotinic cholinergic receptors in postpartum depression. Prog Neuropsychopharmacol Biol Psychiatry. 2013;40:199\u2013206.","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"1853_CR21","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.biopsych.2014.07.021","volume":"77","author":"TC Francis","year":"2015","unstructured":"Francis TC, Chandra R, Friend DM, Finkel E, Dayrit G, Miranda J, et al. Nucleus Accumbens Medium Spiny Neuron Subtypes Mediate Depression-Related Outcomes to Social Defeat Stress. Biol Psychiatry. 2015;77:212\u201322.","journal-title":"Biol Psychiatry"},{"key":"1853_CR22","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1001\/archinte.164.9.1010","volume":"164","author":"DE Ford","year":"2004","unstructured":"Ford DE, Erlinger TP. Depression and C-reactive protein in US adults: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2004;164:1010\u20134.","journal-title":"Arch Intern Med"},{"key":"1853_CR23","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/j.jpsychires.2011.03.006","volume":"45","author":"CP McLean","year":"2011","unstructured":"McLean CP, Asnaani A, Litz BT, Hofmann SG. Gender differences in anxiety disorders: prevalence, course of illness, comorbidity and burden of illness. J Psychiatr Res. 2011;45:1027\u201335.","journal-title":"J Psychiatr Res"},{"key":"1853_CR24","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.pnpbp.2015.04.005","volume":"65","author":"OV Torres","year":"2016","unstructured":"Torres OV, O\u2019Dell LE. Stress is a principal factor that promotes tobacco use in females. Prog Neuropsychopharmacol Biol Psychiatry. 2016;65:260\u20138.","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"1853_CR25","doi-asserted-by":"publisher","first-page":"391","DOI":"10.2165\/00023210-200115050-00005","volume":"15","author":"KA Perkins","year":"2001","unstructured":"Perkins KA. Smoking cessation in women. Special considerations. CNS Drugs. 2001;15:391\u2013411.","journal-title":"CNS Drugs"},{"key":"1853_CR26","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1080\/14622200802097506","volume":"10","author":"KA Perkins","year":"2008","unstructured":"Perkins KA, Scott J. Sex differences in long-term smoking cessation rates due to nicotine patch. Nicotine Tob Res J Soc Res Nicotine Tob. 2008;10:1245\u201350.","journal-title":"Nicotine Tob Res J Soc Res Nicotine Tob"},{"key":"1853_CR27","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/S0893-133X(01)00258-5","volume":"25","author":"S Cheeta","year":"2001","unstructured":"Cheeta S, Irvine EE, Tucci S, Sandhu J, File SE. In adolescence, female rats are more sensitive to the anxiolytic effect of nicotine than are male rats. Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol. 2001;25:601\u20137.","journal-title":"Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol"},{"key":"1853_CR28","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S0091-3057(01)00642-6","volume":"70","author":"MM Faraday","year":"2001","unstructured":"Faraday MM, Elliott BM, Grunberg NE. Adult vs. adolescent rats differ in biobehavioral responses to chronic nicotine administration. Pharm Biochem Behav. 2001;70:475\u201389.","journal-title":"Pharm Biochem Behav"},{"key":"1853_CR29","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.pbb.2003.09.016","volume":"77","author":"BM Elliott","year":"2004","unstructured":"Elliott BM, Faraday MM, Phillips JM, Grunberg NE. Effects of nicotine on elevated plus maze and locomotor activity in male and female adolescent and adult rats. Pharm Biochem Behav. 2004;77:21\u201328.","journal-title":"Pharm Biochem Behav"},{"key":"1853_CR30","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.neulet.2008.05.023","volume":"439","author":"BJ Caldarone","year":"2008","unstructured":"Caldarone BJ, King SL, Picciotto MR. Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice. Neurosci Lett. 2008;439:187\u201391.","journal-title":"Neurosci Lett"},{"key":"1853_CR31","doi-asserted-by":"publisher","first-page":"38","DOI":"10.3389\/fpsyt.2013.00038","volume":"4","author":"OV Torres","year":"2013","unstructured":"Torres OV, Gentil LG, Natividad LA, Carcoba LM, O\u2019Dell LE. Behavioral, Biochemical, and Molecular Indices of Stress are Enhanced in Female Versus Male Rats Experiencing Nicotine Withdrawal. Front Psychiatry. 2013;4:38.","journal-title":"Front Psychiatry"},{"key":"1853_CR32","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1177\/0192623315570339","volume":"43","author":"MC Cora","year":"2015","unstructured":"Cora MC, Kooistra L, Travlos G. Vaginal Cytology of the Laboratory Rat and Mouse: Review and Criteria for the Staging of the Estrous Cycle Using Stained Vaginal Smears. Toxicol Pathol. 2015;43:776\u201393.","journal-title":"Toxicol Pathol"},{"key":"1853_CR33","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1016\/0024-3205(87)90020-8","volume":"40","author":"LC Murrin","year":"1987","unstructured":"Murrin LC, Ferrer JR, Zeng WY, Haley NJ. Nicotine administration to rats: methodological considerations. Life Sci. 1987;40:1699\u2013708.","journal-title":"Life Sci"},{"key":"1853_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0091-3057(89)90419-X","volume":"33","author":"YK Fung","year":"1989","unstructured":"Fung YK, Lau YS. Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems. Pharm Biochem Behav. 1989;33:1\u20136.","journal-title":"Pharm Biochem Behav"},{"key":"1853_CR35","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/978-1-4939-8994-2_10","volume":"1916","author":"A-K Kraeuter","year":"2019","unstructured":"Kraeuter A-K, Guest PC, Sarnyai Z. The Y-Maze for Assessment of Spatial Working and Reference Memory in Mice. Methods Mol Biol Clifton NJ. 2019;1916:105\u201311.","journal-title":"Methods Mol Biol Clifton NJ"},{"key":"1853_CR36","doi-asserted-by":"publisher","first-page":"2948","DOI":"10.1523\/JNEUROSCI.5289-06.2007","volume":"27","author":"GRI Barker","year":"2007","unstructured":"Barker GRI, Bird F, Alexander V, Warburton EC. Recognition Memory for Objects, Place, and Temporal Order: A Disconnection Analysis of the Role of the Medial Prefrontal Cortex and Perirhinal Cortex. J Neurosci. 2007;27:2948\u201357.","journal-title":"J Neurosci"},{"key":"1853_CR37","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.bbr.2015.06.030","volume":"292","author":"JF Morici","year":"2015","unstructured":"Morici JF, Bekinschtein P, Weisstaub NV. Medial prefrontal cortex role in recognition memory in rodents. Behav Brain Res. 2015;292:241\u201351.","journal-title":"Behav Brain Res"},{"key":"1853_CR38","doi-asserted-by":"publisher","unstructured":"Kaidanovich-Beilin O, Lipina T, Vukobradovic I, Roder J, Woodgett JR. Assessment of Social Interaction Behaviors. J Vis Exp. 2011:2473. https:\/\/doi.org\/10.3791\/2473.","DOI":"10.3791\/2473"},{"key":"1853_CR39","first-page":"1297","volume":"27","author":"J Renard","year":"2017","unstructured":"Renard J, Rosen LG, Loureiro M, De Oliveira C, Schmid S, Rushlow WJ, et al. Adolescent Cannabinoid Exposure Induces a Persistent Sub-Cortical Hyper-Dopaminergic State and Associated Molecular Adaptations in the Prefrontal Cortex. Cereb Cortex. 2017;27:1297\u2013310.","journal-title":"Cereb Cortex"},{"key":"1853_CR40","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-11645-8","volume":"7","author":"J Renard","year":"2017","unstructured":"Renard J, Szkudlarek HJ, Kramar CP, Jobson CEL, Moura K, Rushlow WJ, et al. Adolescent THC Exposure Causes Enduring Prefrontal Cortical Disruption of GABAergic Inhibition and Dysregulation of Sub-Cortical Dopamine Function. Sci Rep. 2017;7:11420.","journal-title":"Sci Rep"},{"key":"1853_CR41","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1038\/s41386-018-0282-7","volume":"44","author":"HJ Szkudlarek","year":"2019","unstructured":"Szkudlarek HJ, Desai SJ, Renard J, Pereira B, Norris C, Jobson CEL, et al. \u0394-9-Tetrahydrocannabinol and Cannabidiol produce dissociable effects on prefrontal cortical executive function and regulation of affective behaviors. Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol. 2019;44:817\u201325.","journal-title":"Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol"},{"key":"1853_CR42","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s00441-013-1654-2","volume":"354","author":"B Vollmayr","year":"2013","unstructured":"Vollmayr B, Gass P. Learned helplessness: unique features and translational value of a cognitive depression model. Cell Tissue Res. 2013;354:171\u20138.","journal-title":"Cell Tissue Res"},{"key":"1853_CR43","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/j.neuropharm.2008.12.008","volume":"56","author":"H Tan","year":"2009","unstructured":"Tan H, Bishop SF, Lauzon NM, Sun N, Laviolette SR. Chronic nicotine exposure switches the functional role of mesolimbic dopamine transmission in the processing of nicotine\u2019s rewarding and aversive effects. Neuropharmacology. 2009;56:741\u201351.","journal-title":"Neuropharmacology"},{"key":"1853_CR44","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1021\/jasms.1c00021","volume":"32","author":"C Chen","year":"2021","unstructured":"Chen C, Laviolette SR, Whitehead SN, Renaud JB, Yeung KK-C. Imaging of Neurotransmitters and Small Molecules in Brain Tissues Using Laser Desorption\/Ionization Mass Spectrometry Assisted with Zinc Oxide Nanoparticles. J Am Soc Mass Spectrom. 2021;32:1065\u201379.","journal-title":"J Am Soc Mass Spectrom"},{"key":"1853_CR45","doi-asserted-by":"publisher","unstructured":"Sarikahya MH, Cousineau SL, De Felice M, Szkudlarek HJ, Wong KKW, DeVuono MV, et al. Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex-hippocampal network. Mol Psychiatry. 2023. https:\/\/doi.org\/10.1038\/s41380-023-02190-0.","DOI":"10.1038\/s41380-023-02190-0"},{"key":"1853_CR46","doi-asserted-by":"publisher","first-page":"e2225991","DOI":"10.1001\/jamanetworkopen.2022.25991","volume":"5","author":"HD Dai","year":"2022","unstructured":"Dai HD, Doucet GE, Wang Y, Puga T, Samson K, Xiao P, et al. Longitudinal Assessments of Neurocognitive Performance and Brain Structure Associated With Initiation of Tobacco Use in Children, 2016 to 2021. JAMA Netw Open. 2022;5:e2225991.","journal-title":"JAMA Netw Open"},{"key":"1853_CR47","doi-asserted-by":"publisher","first-page":"e2226001","DOI":"10.1001\/jamanetworkopen.2022.26001","volume":"5","author":"SR Laviolette","year":"2022","unstructured":"Laviolette SR. Understanding the Association of Childhood Tobacco Use With Neuropathological Outcomes and Cognitive Performance Deficits in Vulnerable Brains. JAMA Netw Open. 2022;5:e2226001.","journal-title":"JAMA Netw Open"},{"key":"1853_CR48","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.biopsycho.2008.04.005","volume":"79","author":"DJ Oathes","year":"2008","unstructured":"Oathes DJ, Ray WJ, Yamasaki AS, Borkovec TD, Castonguay LG, Newman MG, et al. Worry, generalized anxiety disorder, and emotion: evidence from the EEG gamma band. Biol Psychol. 2008;79:165\u201370.","journal-title":"Biol Psychol"},{"key":"1853_CR49","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.neuron.2009.12.002","volume":"65","author":"A Adhikari","year":"2010","unstructured":"Adhikari A, Topiwala MA, Gordon JA. Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety. Neuron. 2010;65:257\u201369.","journal-title":"Neuron"},{"key":"1853_CR50","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S0149-7634(01)00041-0","volume":"26","author":"R Lalonde","year":"2002","unstructured":"Lalonde R. The neurobiological basis of spontaneous alternation. Neurosci Biobehav Rev. 2002;26:91\u2013104.","journal-title":"Neurosci Biobehav Rev"},{"key":"1853_CR51","doi-asserted-by":"publisher","first-page":"13998","DOI":"10.1523\/JNEUROSCI.2535-14.2014","volume":"34","author":"S DuBrow","year":"2014","unstructured":"DuBrow S, Davachi L. Temporal memory is shaped by encoding stability and intervening item reactivation. J Neurosci J Soc Neurosci. 2014;34:13998\u20134005.","journal-title":"J Neurosci J Soc Neurosci"},{"key":"1853_CR52","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3389\/fncel.2020.00082","volume":"14","author":"T Yang","year":"2020","unstructured":"Yang T, Nie Z, Shu H, Kuang Y, Chen X, Cheng J, et al. The Role of BDNF on Neural Plasticity in Depression. Front Cell Neurosci. 2020;14:82.","journal-title":"Front Cell Neurosci"},{"key":"1853_CR53","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-36419-8","volume":"9","author":"H Xia","year":"2019","unstructured":"Xia H, Du X, Yin G, Zhang Y, Li X, Cai J, et al. Effects of smoking on cognition and BDNF levels in a male Chinese population: relationship with BDNF Val66Met polymorphism. Sci Rep. 2019;9:217.","journal-title":"Sci Rep"},{"key":"1853_CR54","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.molbrainres.2004.12.020","volume":"136","author":"F Karege","year":"2005","unstructured":"Karege F, Vaudan G, Schwald M, Perroud N, La Harpe R. Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res. 2005;136:29\u201337.","journal-title":"Brain Res Mol Brain Res"},{"key":"1853_CR55","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1093\/cercor\/bhi048","volume":"15","author":"SM Brown","year":"2005","unstructured":"Brown SM, Henning S, Wellman CL. Mild, short-term stress alters dendritic morphology in rat medial prefrontal cortex. Cereb Cortex. 2005;15:1714\u201322.","journal-title":"Cereb Cortex"},{"key":"1853_CR56","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.biopsych.2012.07.025","volume":"74","author":"D Taliaz","year":"2013","unstructured":"Taliaz D, Nagaraj V, Haramati S, Chen A, Zangen A. Altered brain-derived neurotrophic factor expression in the ventral tegmental area, but not in the hippocampus, is essential for antidepressant-like effects of electroconvulsive therapy. Biol Psychiatry. 2013;74:305\u201312.","journal-title":"Biol Psychiatry"},{"key":"1853_CR57","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.biopsych.2013.09.024","volume":"76","author":"P Veeraiah","year":"2014","unstructured":"Veeraiah P, Noronha JM, Maitra S, Bagga P, Khandelwal N, Chakravarty S, et al. Dysfunctional Glutamatergic and \u03b3-Aminobutyric Acidergic Activities in Prefrontal Cortex of Mice in Social Defeat Model of Depression. Biol Psychiatry. 2014;76:231\u20138.","journal-title":"Biol Psychiatry"},{"key":"1853_CR58","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3389\/fncel.2018.00148","volume":"12","author":"B Cz\u00e9h","year":"2018","unstructured":"Cz\u00e9h B, Vardya I, Varga Z, Febbraro F, Csabai D, Martis L-S, et al. Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats. Front Cell Neurosci. 2018;12:148.","journal-title":"Front Cell Neurosci"},{"key":"1853_CR59","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.neubiorev.2019.07.024","volume":"105","author":"CE Page","year":"2019","unstructured":"Page CE, Coutellier L. Prefrontal excitatory\/inhibitory balance in stress and emotional disorders: Evidence for over-inhibition. Neurosci Biobehav Rev. 2019;105:39\u201351.","journal-title":"Neurosci Biobehav Rev"},{"key":"1853_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pscychresns.2005.12.004","volume":"147","author":"A Yildiz-Yesiloglu","year":"2006","unstructured":"Yildiz-Yesiloglu A, Ankerst DP. Review of 1H magnetic resonance spectroscopy findings in major depressive disorder: a meta-analysis. Psychiatry Res. 2006;147:1\u201325.","journal-title":"Psychiatry Res"},{"key":"1853_CR61","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1002\/da.20168","volume":"23","author":"DD Dougherty","year":"2006","unstructured":"Dougherty DD, Bonab AA, Ottowitz WE, Livni E, Alpert NM, Rauch SL, et al. Decreased striatal D1 binding as measured using PET and [11C]SCH 23,390 in patients with major depression with anger attacks. Depress Anxiety. 2006;23:175\u20137.","journal-title":"Depress Anxiety"},{"key":"1853_CR62","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1038\/npp.2008.194","volume":"34","author":"DM Cannon","year":"2009","unstructured":"Cannon DM, Klaver JM, Peck SA, Rallis-Voak D, Erickson K, Drevets WC. Dopamine type-1 receptor binding in major depressive disorder assessed using positron emission tomography and [11C]NNC-112. Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol. 2009;34:1277\u201387.","journal-title":"Neuropsychopharmacol Publ Am Coll Neuropsychopharmacol"},{"key":"1853_CR63","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/BF02246416","volume":"126","author":"D Ebert","year":"1996","unstructured":"Ebert D, Feistel H, Loew T, Pirner A. Dopamine and depression-striatal dopamine D2 receptor SPECT before and after antidepressant therapy. Psychopharmacology. 1996;126:91\u201394.","journal-title":"Psychopharmacology"},{"key":"1853_CR64","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/S0006-3223(01)01089-7","volume":"50","author":"RV Parsey","year":"2001","unstructured":"Parsey RV, Oquendo MA, Zea-Ponce Y, Rodenhiser J, Kegeles LS, Pratap M, et al. Dopamine D(2) receptor availability and amphetamine-induced dopamine release in unipolar depression. Biol Psychiatry. 2001;50:313\u201322.","journal-title":"Biol Psychiatry"},{"key":"1853_CR65","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1007\/s00213-008-1088-9","volume":"197","author":"J Hirvonen","year":"2008","unstructured":"Hirvonen J, Karlsson H, Kajander J, Markkula J, Rasi-Hakala H, N\u00e5gren K, et al. Striatal dopamine D2 receptors in medication-naive patients with major depressive disorder as assessed with [11C]raclopride PET. Psychopharmacology. 2008;197:581\u201390.","journal-title":"Psychopharmacology"},{"key":"1853_CR66","doi-asserted-by":"publisher","first-page":"4908","DOI":"10.1523\/JNEUROSCI.21-13-04908.2001","volume":"21","author":"JW Dalley","year":"2001","unstructured":"Dalley JW, McGaughy J, O\u2019Connell MT, Cardinal RN, Levita L, Robbins TW. Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task. J Neurosci J Soc Neurosci. 2001;21:4908\u201314.","journal-title":"J Neurosci J Soc Neurosci"},{"key":"1853_CR67","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3389\/fncir.2014.00017","volume":"8","author":"B Bloem","year":"2014","unstructured":"Bloem B, Poorthuis R, Mansvelder H. Cholinergic modulation of the medial prefrontal cortex: the role of nicotinic receptors in attention and regulation of neuronal activity. Front Neural Circuits. 2014;8:17.","journal-title":"Front Neural Circuits"},{"key":"1853_CR68","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s00213-006-0549-2","volume":"189","author":"E Hoyle","year":"2006","unstructured":"Hoyle E, Genn RF, Fernandes C, Stolerman IP. Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task. Psychopharmacology. 2006;189:211\u201323.","journal-title":"Psychopharmacology"},{"key":"1853_CR69","doi-asserted-by":"publisher","first-page":"403","DOI":"10.2174\/1570159X15666171103152136","volume":"16","author":"G Valentine","year":"2018","unstructured":"Valentine G, Sofuoglu M. Cognitive Effects of Nicotine: Recent Progress. Curr Neuropharmacol. 2018;16:403\u201314.","journal-title":"Curr Neuropharmacol"},{"key":"1853_CR70","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1111\/j.1601-183X.2005.00176.x","volume":"5","author":"C Fernandes","year":"2006","unstructured":"Fernandes C, Hoyle E, Dempster E, Schalkwyk LC, Collier DA. Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working\/episodic-like memory. Genes Brain Behav. 2006;5:433\u201340.","journal-title":"Genes Brain Behav"},{"key":"1853_CR71","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1126\/science.1207079","volume":"333","author":"K Guillem","year":"2011","unstructured":"Guillem K, Bloem B, Poorthuis RB, Loos M, Smit AB, Maskos U, et al. Nicotinic acetylcholine receptor \u03b22 subunits in the medial prefrontal cortex control attention. Science. 2011;333:888\u201391.","journal-title":"Science"},{"key":"1853_CR72","doi-asserted-by":"publisher","first-page":"12078","DOI":"10.1073\/pnas.1307849110","volume":"110","author":"Y Yang","year":"2013","unstructured":"Yang Y, Paspalas CD, Jin LE, Picciotto MR, Arnsten AFT, Wang M. Nicotinic \u03b17 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex. Proc Natl Acad Sci USA. 2013;110:12078\u201383.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1853_CR73","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1016\/j.neubiorev.2011.04.013","volume":"35","author":"HC Brenhouse","year":"2011","unstructured":"Brenhouse HC, Andersen SL. Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes. Neurosci Biobehav Rev. 2011;35:1687\u2013703.","journal-title":"Neurosci Biobehav Rev"},{"key":"1853_CR74","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.biopsycho.2015.01.003","volume":"0","author":"EL Meerwijk","year":"2015","unstructured":"Meerwijk EL, Ford JM, Weiss SJ. Resting-State EEG Delta Power is Associated with Psychological Pain in Adults with a History of Depression. Biol Psychol. 2015;0:106\u201314.","journal-title":"Biol Psychol"},{"key":"1853_CR75","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.biopsycho.2018.01.003","volume":"132","author":"BD Gr\u00fcnewald","year":"2018","unstructured":"Gr\u00fcnewald BD, Greimel E, Trinkl M, Bartling J, Gro\u00dfheinrich N, Schulte-K\u00f6rne G. Resting frontal EEG asymmetry patterns in adolescents with and without major depression. Biol Psychol. 2018;132:212\u20136.","journal-title":"Biol Psychol"},{"key":"1853_CR76","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-26863-x","volume":"8","author":"AL Proskovec","year":"2018","unstructured":"Proskovec AL, Wiesman AI, Heinrichs-Graham E, Wilson TW. Beta Oscillatory Dynamics in the Prefrontal and Superior Temporal Cortices Predict Spatial Working Memory Performance. Sci Rep. 2018;8:8488.","journal-title":"Sci Rep"},{"key":"1853_CR77","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1038\/sj.mp.4001197","volume":"8","author":"SR Laviolette","year":"2003","unstructured":"Laviolette SR, van der Kooy D. Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area. Mol Psychiatry. 2003;8:50\u20139, 9.","journal-title":"Mol Psychiatry"},{"key":"1853_CR78","doi-asserted-by":"publisher","first-page":"8025","DOI":"10.1523\/JNEUROSCI.1371-08.2008","volume":"28","author":"SR Laviolette","year":"2008","unstructured":"Laviolette SR, Lauzon NM, Bishop SF, Sun N, Tan H. Dopamine signaling through D1-like versus D2-like receptors in the nucleus accumbens core versus shell differentially modulates nicotine reward sensitivity. J Neurosci J Soc Neurosci. 2008;28:8025\u201333.","journal-title":"J Neurosci J Soc Neurosci"},{"key":"1853_CR79","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1038\/nature11713","volume":"493","author":"D Chaudhury","year":"2013","unstructured":"Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 2013;493:532\u20136.","journal-title":"Nature"},{"key":"1853_CR80","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1111\/ejn.12113","volume":"37","author":"JT Yorgason","year":"2013","unstructured":"Yorgason JT, Espa\u00f1a RA, Konstantopoulos JK, Weiner JL, Jones SR. Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats. Eur J Neurosci. 2013;37:1022\u201331.","journal-title":"Eur J Neurosci"},{"key":"1853_CR81","doi-asserted-by":"publisher","first-page":"6561","DOI":"10.1523\/JNEUROSCI.21-17-06561.2001","volume":"21","author":"K Paradiso","year":"2001","unstructured":"Paradiso K, Zhang J, Steinbach JH. The C Terminus of the Human Nicotinic \u03b14\u03b22 Receptor Forms a Binding Site Required for Potentiation by an Estrogenic Steroid. J Neurosci. 2001;21:6561\u20138.","journal-title":"J Neurosci"},{"key":"1853_CR82","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1002\/jnr.23878","volume":"95","author":"SJ Cross","year":"2017","unstructured":"Cross SJ, Linker KE, Leslie FM. Sex dependent effects of nicotine on the developing brain. J Neurosci Res. 2017;95:422\u201336.","journal-title":"J Neurosci Res"},{"key":"1853_CR83","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1002\/cne.21026","volume":"497","author":"ML Centeno","year":"2006","unstructured":"Centeno ML, Henderson JA, Pau K-YF, Bethea CL. Estradiol increases alpha7 nicotinic receptor in serotonergic dorsal raphe and noradrenergic locus coeruleus neurons of macaques. J Comp Neurol. 2006;497:489\u2013501.","journal-title":"J Comp Neurol"},{"key":"1853_CR84","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/S0014-2999(01)01389-9","volume":"430","author":"K Nakazawa","year":"2001","unstructured":"Nakazawa K, Ohno Y. Modulation by estrogens and xenoestrogens of recombinant human neuronal nicotinic receptors. Eur J Pharm. 2001;430:175\u201383.","journal-title":"Eur J Pharm"},{"key":"1853_CR85","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/j.clpt.2006.01.008","volume":"79","author":"NL Benowitz","year":"2006","unstructured":"Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P. Female sex and oral contraceptive use accelerate nicotine metabolism. Clin Pharm Ther. 2006;79:480\u20138.","journal-title":"Clin Pharm Ther"},{"key":"1853_CR86","first-page":"823","volume":"16","author":"GA Kyerematen","year":"1988","unstructured":"Kyerematen GA, Owens GF, Chattopadhyay B, deBethizy JD, Vesell ES. Sexual dimorphism of nicotine metabolism and distribution in the rat. Studies in vivo and in vitro. Drug Metab Dispos Biol Fate Chem. 1988;16:823\u20138.","journal-title":"Drug Metab Dispos Biol Fate Chem"},{"key":"1853_CR87","doi-asserted-by":"publisher","first-page":"2596","DOI":"10.1210\/en.2018-00220","volume":"159","author":"MR Bell","year":"2018","unstructured":"Bell MR. Comparing Postnatal Development of Gonadal Hormones and Associated Social Behaviors in Rats, Mice, and Humans. Endocrinology. 2018;159:2596\u2013613.","journal-title":"Endocrinology"}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01853-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01853-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01853-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T17:03:30Z","timestamp":1716311010000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01853-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,23]]},"references-count":87,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1853"],"URL":"https:\/\/doi.org\/10.1038\/s41386-024-01853-y","relation":{},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,23]]},"assertion":[{"value":"12 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 March 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}