{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:42:12Z","timestamp":1793299332896,"version":"4.5.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Rappaport Mental Health Research Scholar Award from the Phyllis & Jerome Lyle Rappaport Foundation"},{"DOI":"10.13039\/100000025","name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health","doi-asserted-by":"publisher","award":["P50MH115874"],"award-info":[{"award-number":["P50MH115874"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health","doi-asserted-by":"publisher","award":["P50MH115874"],"award-info":[{"award-number":["P50MH115874"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH063266"],"award-info":[{"award-number":["R01MH063266"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health"},{"name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neuropsychopharmacol."],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1038\/s41386-024-01978-0","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T17:02:25Z","timestamp":1724864545000},"page":"401-409","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Acute sleep disruption reduces fear memories in male and female mice"],"prefix":"10.1038","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0049-1930","authenticated-orcid":false,"given":"Allison R.","family":"Foilb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa M.","family":"Taylor-Yeremeeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett D.","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5158-1103","authenticated-orcid":false,"given":"Kerry J.","family":"Ressler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4162-3947","authenticated-orcid":false,"suffix":"Jr.","given":"William A.","family":"Carlezon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"key":"1978_CR1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5. Washington D.C.: American Psychiatric Association; 2013.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"1978_CR2","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1080\/15402002.2016.1141770","volume":"15","author":"J Watling","year":"2017","unstructured":"Watling J, Pawlik B, Scott K, Booth S, Short MA. Sleep loss and affective functioning: more than just mood. Behav Sleep Med. 2017;15:394\u2013409.","journal-title":"Behav Sleep Med"},{"key":"1978_CR3","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.neubiorev.2007.06.001","volume":"32","author":"AC Pawlyk","year":"2008","unstructured":"Pawlyk AC, Morrison AR, Ross RJ, Brennan FX. Stress-induced changes in sleep in rodents: models and mechanisms. Neurosci Biobehav Rev. 2008;32:99\u2013117.","journal-title":"Neurosci Biobehav Rev"},{"key":"1978_CR4","doi-asserted-by":"crossref","unstructured":"Armitage R. Sleep and circadian rhythms in mood disorders. Acta Psychiatr Scand Suppl. 2007;433:104\u201315.","DOI":"10.1111\/j.1600-0447.2007.00968.x"},{"key":"1978_CR5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.smrv.2017.05.002","volume":"39","author":"F Raven","year":"2018","unstructured":"Raven F, Van der Zee EA, Meerlo P, Havekes R. The role of sleep in regulating structural plasticity and synaptic strength: Implications for memory and cognitive function. Sleep Med Rev. 2018;39:3\u201311.","journal-title":"Sleep Med Rev"},{"key":"1978_CR6","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/npr2.12311","volume":"43","author":"H Cohen","year":"2023","unstructured":"Cohen H, Ephraim-Oluwanuga OT, Akintunde OT, Gureje O, Matar MA, Todder D, et al. The potential beneficial effect of sleep deprivation following traumatic events to preventing PTSD: Review of current insight regarding sleep, memory, and trauma resonating with ancient rituals-\u00c0\u00ecs\u00f9n Oku (African) and Tsuya (Japanese). Neuropsychopharmacol Rep. 2023;43:2\u201311.","journal-title":"Neuropsychopharmacol Rep"},{"key":"1978_CR7","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1101\/lm.48803","volume":"10","author":"LA Graves","year":"2003","unstructured":"Graves LA, Heller EA, Pack AI, Abel T. Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning. Learn Mem. 2003;10:168\u201376.","journal-title":"Learn Mem"},{"key":"1978_CR8","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.neuron.2019.03.017","volume":"102","author":"SA Maddox","year":"2019","unstructured":"Maddox SA, Hartmann J, Ross RA, Ressler KJ. Deconstructing the gestalt: mechanisms of fear, threat, and trauma memory encoding. Neuron. 2019;102:60\u201374.","journal-title":"Neuron"},{"key":"1978_CR9","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/s41582-022-00635-8","volume":"18","author":"KJ Ressler","year":"2022","unstructured":"Ressler KJ, Berretta S, Bolshakov VY, Rosso IM, Meloni EG, Rauch SL, et al. Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits. Nat Rev Neurol. 2022;18:273\u201388.","journal-title":"Nat Rev Neurol"},{"key":"1978_CR10","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1111\/j.0953-816X.2004.03426.x","volume":"19","author":"DN Ruskin","year":"2004","unstructured":"Ruskin DN, Liu C, Dunn KE, Bazan NG, LaHoste GJ. Sleep deprivation impairs hippocampus\u2010mediated contextual learning but not amygdala\u2010mediated cued learning in rats. Eur J of Neuroscience. 2004;19:3121\u20134.","journal-title":"Eur J of Neuroscience"},{"key":"1978_CR11","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1093\/cercor\/bhu310","volume":"26","author":"P Ravassard","year":"2016","unstructured":"Ravassard P, Hamieh AM, Joseph MA, Fraize N, Libourel P-A, Lebarillier L, et al. REM sleep-dependent bidirectional regulation of hippocampal-based emotional memory and LTP. Cereb Cortex. 2016;26:1488\u20131500.","journal-title":"Cereb Cortex"},{"key":"1978_CR12","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.physbeh.2018.08.008","volume":"196","author":"AS Hunter","year":"2018","unstructured":"Hunter AS. REM deprivation but not sleep fragmentation produces a sex-specific impairment in extinction. Physiol Behav. 2018;196:84\u201394.","journal-title":"Physiol Behav"},{"key":"1978_CR13","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1146\/annurev.psych.55.090902.142050","volume":"55","author":"Y Dudai","year":"2004","unstructured":"Dudai Y. The neurobiology of consolidations, or, how stable is the engram? Annu Rev Psychol. 2004;55:51\u201386.","journal-title":"Annu Rev Psychol"},{"key":"1978_CR14","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/385533a0","volume":"385","author":"U Frey","year":"1997","unstructured":"Frey U, Morris RG. Synaptic tagging and long-term potentiation. Nature. 1997;385:533\u20136.","journal-title":"Nature"},{"key":"1978_CR15","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0028-3908(98)00040-9","volume":"37","author":"U Frey","year":"1998","unstructured":"Frey U, Morris RG. Weak before strong: dissociating synaptic tagging and plasticity-factor accounts of late-LTP. Neuropharmacology. 1998;37:545\u201352.","journal-title":"Neuropharmacology"},{"key":"1978_CR16","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0091-3057(78)90269-1","volume":"8","author":"HP Davis","year":"1978","unstructured":"Davis HP, Rosenzweig MR. Recovery as a function of the degree of amnesia due to protein synthesis inhibition. Pharmacol Biochem Behav. 1978;8:701\u201310.","journal-title":"Pharmacol Biochem Behav"},{"key":"1978_CR17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.neuron.2006.11.025","volume":"53","author":"P Bekinschtein","year":"2007","unstructured":"Bekinschtein P, Cammarota M, Igaz LM, Bevilaqua LRM, Izquierdo I, Medina JH. Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. Neuron. 2007;53:261\u201377.","journal-title":"Neuron"},{"key":"1978_CR18","doi-asserted-by":"crossref","first-page":"12547","DOI":"10.1523\/JNEUROSCI.0324-14.2014","volume":"34","author":"D Bambah-Mukku","year":"2014","unstructured":"Bambah-Mukku D, Travaglia A, Chen DY, Pollonini G, Alberini CM. A positive autoregulatory BDNF feedback loop via C\/EBP\u03b2 mediates hippocampal memory consolidation. J Neurosci. 2014;34:12547\u201359.","journal-title":"J Neurosci"},{"key":"1978_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsmc.2014.11.007","volume":"10","author":"BS McEwen","year":"2015","unstructured":"McEwen BS, Karatsoreos IN. Sleep deprivation and circadian disruption: stress, allostasis, and allostatic load. Sleep Med Clin. 2015;10:1\u201310.","journal-title":"Sleep Med Clin"},{"key":"1978_CR20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.smrv.2007.07.007","volume":"12","author":"P Meerlo","year":"2008","unstructured":"Meerlo P, Sgoifo A, Suchecki D. Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity. Sleep Med Rev. 2008;12:197\u2013210.","journal-title":"Sleep Med Rev"},{"key":"1978_CR21","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1749-6632.1986.tb14630.x","volume":"467","author":"H Anisman","year":"1986","unstructured":"Anisman H, Zacharko RM. Behavioral and neurochemical consequences associated with stressors. Ann N Y Acad Sci. 1986;467:205\u201325.","journal-title":"Ann N Y Acad Sci"},{"key":"1978_CR22","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nrn2651","volume":"10","author":"B Roozendaal","year":"2009","unstructured":"Roozendaal B, McEwen BS, Chattarji S. Stress, memory and the amygdala. Nat Rev Neurosci. 2009;10:423\u201333.","journal-title":"Nat Rev Neurosci"},{"key":"1978_CR23","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.neuron.2022.02.020","volume":"110","author":"L Schwabe","year":"2022","unstructured":"Schwabe L, Hermans EJ, Jo\u00ebls M, Roozendaal B. Mechanisms of memory under stress. Neuron. 2022;110:1450\u201367.","journal-title":"Neuron"},{"key":"1978_CR24","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.neuron.2023.10.002","volume":"112","author":"M Wu","year":"2024","unstructured":"Wu M, Zhang X, Feng S, Freda SN, Kumari P, Dumrongprechachan V, et al. Dopamine pathways mediating affective state transitions after sleep loss. Neuron. 2024;112:141\u2013154.e8.","journal-title":"Neuron"},{"key":"1978_CR25","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/B978-0-12-420170-5.00006-4","volume":"122","author":"R Andero","year":"2014","unstructured":"Andero R, Choi DC, Ressler KJ. BDNF-TrkB receptor regulation of distributed adult neural plasticity, memory formation, and psychiatric disorders. Prog Mol Biol Transl Sci. 2014;122:169\u201392.","journal-title":"Prog Mol Biol Transl Sci"},{"key":"1978_CR26","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1038\/nn1718","volume":"9","author":"JP Chhatwal","year":"2006","unstructured":"Chhatwal JP, Stanek-Rattiner L, Davis M, Ressler KJ. Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci. 2006;9:870\u20132.","journal-title":"Nat Neurosci"},{"key":"1978_CR27","doi-asserted-by":"crossref","first-page":"e62205","DOI":"10.1371\/journal.pone.0062205","volume":"8","author":"JC Ehlen","year":"2013","unstructured":"Ehlen JC, Hesse S, Pinckney L, Paul KN. Sex chromosomes regulate nighttime sleep propensity during recovery from sleep loss in mice. PLoS One. 2013;8:e62205.","journal-title":"PLoS One"},{"key":"1978_CR28","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0006-8993(96)00652-X","volume":"734","author":"J Fang","year":"1996","unstructured":"Fang J, Fishbein W. Sex differences in paradoxical sleep: influences of estrus cycle and ovariectomy. Brain Res. 1996;734:275\u201385.","journal-title":"Brain Res"},{"key":"1978_CR29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neuroscience.2019.11.046","volume":"427","author":"A Kostin","year":"2020","unstructured":"Kostin A, Alam MA, Siegel JM, McGinty D, Alam MN. Sex- and age-dependent differences in sleep-wake characteristics of Fisher-344 Rats. Neuroscience. 2020;427:29\u201342.","journal-title":"Neuroscience"},{"key":"1978_CR30","doi-asserted-by":"crossref","first-page":"20150110","DOI":"10.1098\/rstb.2015.0110","volume":"371","author":"JA Mong","year":"2016","unstructured":"Mong JA, Cusmano DM. Sex differences in sleep: impact of biological sex and sex steroids. Philos Trans R Soc Lond B Biol Sci. 2016;371:20150110.","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"1978_CR31","doi-asserted-by":"crossref","unstructured":"Foilb AR, Taylor-Yeremeeva EM, Fritsch EL, Ravichandran C, Lezak KR, Missig G, et al. Differential effects of the stress peptides PACAP and CRF on sleep architecture in mice. NPP\u2014Digit Psychiatry Neurosci, 2024;2;3.","DOI":"10.1038\/s44277-024-00003-y"},{"key":"1978_CR32","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/sleep\/26.3.267","volume":"26","author":"M Koehl","year":"2003","unstructured":"Koehl M, Battle SE, Turek FW. Sleep in female mice: a strain comparison across the estrous cycle. Sleep. 2003;26:267\u201372.","journal-title":"Sleep"},{"key":"1978_CR33","doi-asserted-by":"crossref","first-page":"7118","DOI":"10.1073\/pnas.0602006103","volume":"103","author":"P Franken","year":"2006","unstructured":"Franken P, Dudley CA, Estill SJ, Barakat M, Thomason R, O\u2019Hara BF, et al. NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions. Proc Natl Acad Sci USA. 2006;103:7118\u201323.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1978_CR34","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1093\/sleep\/29.9.1211","volume":"29","author":"KN Paul","year":"2006","unstructured":"Paul KN, Dugovic C, Turek FW, Laposky AD. Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function. Sleep. 2006;29:1211\u201323.","journal-title":"Sleep"},{"key":"1978_CR35","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.patbio.2014.07.005","volume":"62","author":"C Lord","year":"2014","unstructured":"Lord C, Sekerovic Z, Carrier J. Sleep regulation and sex hormones exposure in men and women across adulthood. Pathol Biol. 2014;62:302\u201310.","journal-title":"Pathol Biol"},{"key":"1978_CR36","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0006-8993(80)91076-8","volume":"185","author":"S Yamaoka","year":"1980","unstructured":"Yamaoka S. Modification of circadian sleep rhythms by gonadal steroids and the neural mechanisms involved. Brain Res. 1980;185:385\u201398.","journal-title":"Brain Res"},{"key":"1978_CR37","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/archpsyc.1995.03950240066012","volume":"52","author":"RC Kessler","year":"1995","unstructured":"Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry. 1995;52:1048\u201360.","journal-title":"Arch Gen Psychiatry"},{"key":"1978_CR38","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ynstr.2014.09.005","volume":"1","author":"RM Shansky","year":"2015","unstructured":"Shansky RM. Sex differences in PTSD resilience and susceptibility: challenges for animal models of fear learning. Neurobiol Stress. 2015;1:60\u201365.","journal-title":"Neurobiol Stress"},{"key":"1978_CR39","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2014.67","volume":"4","author":"KK Cover","year":"2014","unstructured":"Cover KK, Maeng LY, Lebr\u00f3n-Milad K, Milad MR. Mechanisms of estradiol in fear circuitry: implications for sex differences in psychopathology. Transl Psychiatry. 2014;4:e422.","journal-title":"Transl Psychiatry"},{"key":"1978_CR40","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ynstr.2018.07.001","volume":"9","author":"LD Straus","year":"2018","unstructured":"Straus LD, Norman SB, Risbrough VB, Acheson DT, Drummond SPA. REM sleep and safety signal learning in posttraumatic stress disorder: a preliminary study in military veterans. Neurobiol Stress. 2018;9:22\u201328.","journal-title":"Neurobiol Stress"},{"key":"1978_CR41","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1080\/15402002.2011.654296","volume":"10","author":"I Kobayashi","year":"2012","unstructured":"Kobayashi I, Mellman TA. Gender differences in sleep during the aftermath of trauma and the development of posttraumatic stress disorder. Behav Sleep Med. 2012;10:180\u201390.","journal-title":"Behav Sleep Med"},{"key":"1978_CR42","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/2042-6410-3-29","volume":"3","author":"I Kobayashi","year":"2012","unstructured":"Kobayashi I, Cowdin N, Mellman TA. One\u2019s sex, sleep, and posttraumatic stress disorder. Biol Sex Differ. 2012;3:29.","journal-title":"Biol Sex Differ"},{"key":"1978_CR43","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1037\/bul0000014","volume":"141","author":"EF Pace-Schott","year":"2015","unstructured":"Pace-Schott EF, Germain A, Milad MR. Effects of sleep on memory for conditioned fear and fear extinction. Psychol Bull. 2015;141:835\u201357.","journal-title":"Psychol Bull"},{"key":"1978_CR44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.janxdis.2009.08.002","volume":"24","author":"KA Babson","year":"2010","unstructured":"Babson KA, Feldner MT. Temporal relations between sleep problems and both traumatic event exposure and PTSD: a critical review of the empirical literature. J Anxiety Disord. 2010;24:1\u201315.","journal-title":"J Anxiety Disord"},{"key":"1978_CR45","volume":"11","author":"KM McCullough","year":"2020","unstructured":"McCullough KM, Chatzinakos C, Hartmann J, Missig G, Neve RL, Fenster RJ, et al. Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning. Nat Commun. 2020;11:5180.","journal-title":"Nat Commun"},{"key":"1978_CR46","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/npp.2017.243","volume":"43","author":"G Missig","year":"2018","unstructured":"Missig G, Mokler EL, Robbins JO, Alexander AJ, McDougle CJ, Carlezon WA. Perinatal immune activation produces persistent sleep alterations and epileptiform activity in male mice. Neuropsychopharmacology. 2018;43:482\u201391.","journal-title":"Neuropsychopharmacology"},{"key":"1978_CR47","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.biopsych.2020.12.030","volume":"89","author":"KM McCullough","year":"2021","unstructured":"McCullough KM, Missig G, Robble MA, Foilb AR, Wells AM, Hartmann J, et al. Nucleus accumbens medium spiny neuron subtypes differentially regulate stress-associated alterations in sleep architecture. Biol Psychiatry. 2021;89:1138\u201349.","journal-title":"Biol Psychiatry"},{"key":"1978_CR48","doi-asserted-by":"crossref","first-page":"7656","DOI":"10.1523\/JNEUROSCI.0885-17.2017","volume":"37","author":"AM Wells","year":"2017","unstructured":"Wells AM, Ridener E, Bourbonais CA, Kim W, Pantazopoulos H, Carroll FI, et al. Effects of chronic social defeat stress on sleep and circadian rhythms are mitigated by kappa-opioid receptor antagonism. J Neurosci. 2017;37:7656\u201368.","journal-title":"J Neurosci"},{"key":"1978_CR49","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1126\/science.1186909","volume":"328","author":"J Peters","year":"2010","unstructured":"Peters J, Dieppa-Perea LM, Melendez LM, Quirk GJ. Induction of fear extinction with hippocampal-infralimbic BDNF. Science. 2010;328:1288\u201390.","journal-title":"Science"},{"key":"1978_CR50","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1523\/JNEUROSCI.4085-12.2014","volume":"34","author":"SA Heldt","year":"2014","unstructured":"Heldt SA, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler KJ. BDNF deletion or TrkB impairment in amygdala inhibits both appetitive and aversive learning. J Neurosci. 2014;34:2444\u201350.","journal-title":"J Neurosci"},{"key":"1978_CR51","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.conb.2018.08.012","volume":"54","author":"RL Ressler","year":"2019","unstructured":"Ressler RL, Maren S. Synaptic encoding of fear memories in the amygdala. Curr Opin Neurobiol. 2019;54:54\u201359.","journal-title":"Curr Opin Neurobiol"},{"key":"1978_CR52","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/29.9.e45","volume":"29","author":"MW Pfaffl","year":"2001","unstructured":"Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29:e45.","journal-title":"Nucleic Acids Res"},{"key":"1978_CR53","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/ilar\/ilu008","volume":"55","author":"TD Goode","year":"2014","unstructured":"Goode TD, Maren S. Animal models of fear relapse. ILAR J. 2014;55:246\u201358.","journal-title":"ILAR J"},{"key":"1978_CR54","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1101\/lm.36801","volume":"8","author":"U Wagner","year":"2001","unstructured":"Wagner U, Gais S, Born J. Emotional memory formation is enhanced across sleep intervals with high amounts of rapid eye movement sleep. Learn Mem. 2001;8:112\u20139.","journal-title":"Learn Mem"},{"key":"1978_CR55","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1093\/cercor\/bhn155","volume":"19","author":"M Nishida","year":"2009","unstructured":"Nishida M, Pearsall J, Buckner RL, Walker MP. REM sleep, prefrontal theta, and the consolidation of human emotional memory. Cereb Cortex. 2009;19:1158\u201366.","journal-title":"Cereb Cortex"},{"key":"1978_CR56","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/nature07166","volume":"454","author":"C Herry","year":"2008","unstructured":"Herry C, Ciocchi S, Senn V, Demmou L, M\u00fcller C, L\u00fcthi A. Switching on and off fear by distinct neuronal circuits. Nature. 2008;454:600\u20136.","journal-title":"Nature"},{"key":"1978_CR57","doi-asserted-by":"crossref","first-page":"10396","DOI":"10.1523\/JNEUROSCI.5539-12.2013","volume":"33","author":"AM Jasnow","year":"2013","unstructured":"Jasnow AM, Ehrlich DE, Choi DC, Dabrowska J, Bowers ME, McCullough KM, et al. Thy1-expressing neurons in the basolateral amygdala may mediate fear inhibition. J Neurosci. 2013;33:10396\u2013404.","journal-title":"J Neurosci"},{"key":"1978_CR58","doi-asserted-by":"crossref","first-page":"4796","DOI":"10.1523\/JNEUROSCI.5654-03.2004","volume":"24","author":"LM Rattiner","year":"2004","unstructured":"Rattiner LM, Davis M, French CT, Ressler KJ. Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. J Neurosci. 2004;24:4796\u2013806.","journal-title":"J Neurosci"},{"key":"1978_CR59","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1006\/exnr.2000.7415","volume":"164","author":"BR Ickes","year":"2000","unstructured":"Ickes BR, Pham TM, Sanders LA, Albeck DS, Mohammed AH, Granholm AC. Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain. Exp Neurol. 2000;164:45\u201352.","journal-title":"Exp Neurol"},{"key":"1978_CR60","volume":"9","author":"T-Y Zhang","year":"2018","unstructured":"Zhang T-Y, Keown CL, Wen X, Li J, Vousden DA, Anacker C, et al. Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus. Nat Commun. 2018;9:298.","journal-title":"Nat Commun"}],"updated-by":[{"DOI":"10.1038\/s41386-025-02056-9","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000}}],"container-title":["Neuropsychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01978-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01978-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01978-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T10:42:08Z","timestamp":1740739328000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41386-024-01978-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,28]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["1978"],"URL":"https:\/\/doi.org\/10.1038\/s41386-024-01978-0","relation":{"correction":[{"id-type":"doi","id":"10.1038\/s41386-025-02056-9","asserted-by":"object"}]},"ISSN":["0893-133X","1740-634X"],"issn-type":[{"value":"0893-133X","type":"print"},{"value":"1740-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,28]]},"assertion":[{"value":"30 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2025","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1038\/s41386-025-02056-9","URL":"https:\/\/doi.org\/10.1038\/s41386-025-02056-9","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"WAC and KJR are members of the NPP editorial board. WAC is a consultant for Psy Therapeutics and has sponsored research agreements with Cerevel Therapeutics and Delix Therapeutics. KJR has performed scientific consultation for Bioxcel, Bionomics, Acer, Takeda, and Jazz Pharma; serves on Scientific Advisory Boards for Sage and the Brain Research Foundation, and he has received sponsored research support from Takeda, Brainsway, and Alto Neuroscience. ARF, EMTY, and BDS report no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}