{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:35:47Z","timestamp":1791516947866,"version":"4.3.4"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nutr. Diabetes"],"DOI":"10.1038\/s41387-025-00405-7","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T16:04:24Z","timestamp":1764000264000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Global burden of 13 non-communicable diseases attributable to high fasting plasma glucose from the GBD 2021 study"],"prefix":"10.1038","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1528-1701","authenticated-orcid":false,"given":"Junfeng","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9477-2979","authenticated-orcid":false,"given":"Zhengbin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2527-0954","authenticated-orcid":false,"given":"Shugen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1571-8981","authenticated-orcid":false,"given":"Yong","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3895-6509","authenticated-orcid":false,"given":"Zhao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3101-5788","authenticated-orcid":false,"given":"Jiao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7805-2191","authenticated-orcid":false,"given":"Ning","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6566-8755","authenticated-orcid":false,"given":"Yingjie","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"key":"405_CR1","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1016\/j.tibtech.2016.04.012","volume":"34","author":"BC Mulukutla","year":"2016","unstructured":"Mulukutla BC, Yongky A, Le T, Mashek DG, Hu WS. Regulation of glucose metabolism - a perspective from cell bioprocessing. Trends Biotechnol. 2016;34:638\u201351.","journal-title":"Trends Biotechnol"},{"key":"405_CR2","doi-asserted-by":"publisher","first-page":"2626","DOI":"10.1007\/s00125-024-06253-x","volume":"67","author":"LW Wat","year":"2024","unstructured":"Wat LW, Svensson KJ. Novel secreted regulators of glucose and lipid metabolism in the development of metabolic diseases. Diabetologia. 2024;67:2626\u201336.","journal-title":"Diabetologia"},{"key":"405_CR3","doi-asserted-by":"publisher","first-page":"2282","DOI":"10.3390\/microorganisms9112282","volume":"9","author":"MD Ngo","year":"2021","unstructured":"Ngo MD, Bartlett S, Ronacher K. Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. dyslipidemia. Microorganisms. 2021;9:2282.","journal-title":"Microorganisms"},{"key":"405_CR4","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/s41569-023-00877-z","volume":"20","author":"ND Wong","year":"2023","unstructured":"Wong ND, Sattar N. Cardiovascular risk in diabetes mellitus: epidemiology, assessment and prevention. Nat Rev Cardiol. 2023;20:685\u201395.","journal-title":"Nat Rev Cardiol"},{"key":"405_CR5","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.3390\/medicina60111783","volume":"60","author":"I Ilic","year":"2024","unstructured":"Ilic I, Jakovljevic V, Zivanovic Macuzic I, Ravic-Nikolic A, Ilic M, Sorak M, et al. Trends in global burden of Alzheimer\u2019s disease and other dementias attributable to high fasting plasma glucose, 1990-2021. Medicina. 2024;60:1783.","journal-title":"Medicina"},{"key":"405_CR6","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1097\/CM9.0000000000003143","volume":"138","author":"J Chen","year":"2025","unstructured":"Chen J, Li C, Bu C, Wang Y, Qi M, Fu P, et al. Global burden of non-communicable diseases attributable to kidney dysfunction with projection into 2040. Chin Med J (Engl). 2025;138:1334\u201344.","journal-title":"Chin Med J (Engl)"},{"key":"405_CR7","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0140-6736(11)60679-X","volume":"378","author":"G Danaei","year":"2011","unstructured":"Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2\u00b77 million participants. Lancet. 2011;378:31\u201340.","journal-title":"Lancet"},{"key":"405_CR8","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1016\/S0140-6736(24)02317-1","volume":"404","author":"NCD-RisC) NRFC.","year":"2024","unstructured":"(NCD-RisC) NRFC. Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants. Lancet. 2024;404:2077\u201393.","journal-title":"Lancet"},{"key":"405_CR9","doi-asserted-by":"publisher","first-page":"103025","DOI":"10.1016\/j.dsx.2024.103025","volume":"18","author":"XJ Dong","year":"2024","unstructured":"Dong XJ, Zhang XQ, Wang BB, Hou FF, Jiao Y. The burden of cardiovascular disease attributable to high fasting plasma glucose: findings from the global burden of disease study 2019. Diabetes Metab Syndr. 2024;18:103025.","journal-title":"Diabetes Metab Syndr"},{"key":"405_CR10","doi-asserted-by":"publisher","first-page":"1379634","DOI":"10.3389\/fendo.2024.1379634","volume":"15","author":"H Wei","year":"2024","unstructured":"Wei H, Ren J, Li R, Qi X, Yang F, Li Q. Global, regional, and national burden of chronic kidney disease attributable to high fasting plasma glucose from 1990 to 2019: a systematic analysis from the global burden of disease study 2019. Front Endocrinol. 2024;15:1379634.","journal-title":"Front Endocrinol"},{"key":"405_CR11","doi-asserted-by":"publisher","first-page":"879890","DOI":"10.3389\/fendo.2022.879890","volume":"13","author":"S Safiri","year":"2022","unstructured":"Safiri S, Nejadghaderi SA, Karamzad N, Kaufman JS, Carson-Chahhoud K, Bragazzi NL, et al. Global, regional and national burden of cancers attributable to high fasting plasma glucose in 204 countries and territories, 1990-2019. Front Endocrinol. 2022;13:879890.","journal-title":"Front Endocrinol"},{"key":"405_CR12","doi-asserted-by":"publisher","first-page":"2752","DOI":"10.1111\/dom.15594","volume":"26","author":"J Zhang","year":"2024","unstructured":"Zhang J, Xu S, Liu X, Zhang J, Hu S, Liu X, et al. Time trends and regional variation in utilization of antidiabetic medicines in China, 2015-2022. Diabetes Obes Metab. 2024;26:2752\u201360.","journal-title":"Diabetes Obes Metab"},{"key":"405_CR13","doi-asserted-by":"publisher","first-page":"211","DOI":"10.4093\/dmj.2022.0346","volume":"47","author":"J Park","year":"2023","unstructured":"Park J, Kim G, Kim BS, Han KD, Kwon SY, Park SH, et al. Insulin fact sheet in type 1 and 2 diabetes mellitus and trends of antidiabetic medication use in insulin users with type 2 diabetes mellitus: 2002 to 2019. Diabetes Metab J. 2023;47:211\u20139.","journal-title":"Diabetes Metab J"},{"key":"405_CR14","doi-asserted-by":"publisher","first-page":"2133","DOI":"10.1016\/S0140-6736(24)00757-8","volume":"403","author":"Collaborators G2DaI.","year":"2024","unstructured":"Collaborators G2DaI. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403:2133\u201361.","journal-title":"Lancet"},{"key":"405_CR15","doi-asserted-by":"publisher","first-page":"2100","DOI":"10.1016\/S0140-6736(24)00367-2","volume":"403","author":"GBD 2021 Causes of Death Collaborators.","year":"2024","unstructured":"GBD 2021 Causes of Death Collaborators. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403:2100\u201332.","journal-title":"Lancet"},{"key":"405_CR16","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1016\/S0140-6736(24)00933-4","volume":"403","author":"GBD 2021 Risk Factors Collaborators.","year":"2024","unstructured":"GBD 2021 Risk Factors Collaborators. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403:2162\u2013203.","journal-title":"Lancet"},{"key":"405_CR17","doi-asserted-by":"publisher","first-page":"102713","DOI":"10.1016\/j.eclinm.2024.102713","volume":"74","author":"P Sun","year":"2024","unstructured":"Sun P, Yu C, Yin L, Chen Y, Sun Z, Zhang T, et al. Global, regional, and national burden of female cancers in women of child-bearing age, 1990-2021: analysis of data from the global burden of disease study 2021. EClinicalMedicine. 2024;74:102713.","journal-title":"EClinicalMedicine"},{"key":"405_CR18","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1016\/S0140-6736(24)00476-8","volume":"403","author":"GBD 2021 Demographics Collaborators.","year":"2024","unstructured":"GBD 2021 Demographics Collaborators. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403:1989\u20132056.","journal-title":"Lancet"},{"key":"405_CR19","doi-asserted-by":"publisher","first-page":"19614","DOI":"10.18632\/aging.203374","volume":"13","author":"X Yang","year":"2021","unstructured":"Yang X, Chen H, Zhang T, Yin X, Man J, He Q, et al. Global, regional, and national burden of blindness and vision loss due to common eye diseases along with its attributable risk factors from 1990 to 2019: a systematic analysis from the global burden of disease study 2019. Aging. 2021;13:19614\u201342.","journal-title":"Aging"},{"key":"405_CR20","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1111\/1753-0407.13072","volume":"12","author":"L Ye","year":"2020","unstructured":"Ye L, Xu J, Zhang T, Lin X, Pan X, Zeng W, et al. Global burden of noncommunicable diseases attributable to high fasting plasma glucose. J Diabetes. 2020;12:807\u201318.","journal-title":"J Diabetes"},{"key":"405_CR21","first-page":"100483","volume":"21","author":"IR Hambleton","year":"2023","unstructured":"Hambleton IR, Caixeta R, Jeyaseelan SM, Luciani S, Hennis A. The rising burden of non-communicable diseases in the Americas and the impact of population aging: a secondary analysis of available data. Lancet Reg Health Am. 2023;21:100483.","journal-title":"Lancet Reg Health Am"},{"key":"405_CR22","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1038\/s41581-024-00863-9","volume":"20","author":"NC Chesnaye","year":"2024","unstructured":"Chesnaye NC, Ortiz A, Zoccali C, Stel VS, Jager KJ. The impact of population ageing on the burden of chronic kidney disease. Nat Rev Nephrol. 2024;20:569\u201385.","journal-title":"Nat Rev Nephrol"},{"key":"405_CR23","doi-asserted-by":"publisher","first-page":"04093","DOI":"10.7189\/jogh.12.04093","volume":"12","author":"JY Xi","year":"2022","unstructured":"Xi JY, Lin X, Hao YT. Measurement and projection of the burden of disease attributable to population aging in 188 countries, 1990-2050: a population-based study. J Glob Health. 2022;12:04093.","journal-title":"J Glob Health"},{"key":"405_CR24","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1111\/bju.15659","volume":"129","author":"MZ Aslam","year":"2022","unstructured":"Aslam MZ, Trail M, Cassell AK, Khan AB, Payne S. Establishing a sustainable healthcare environment in low- and middle-income countries. BJU Int. 2022;129:134\u201342.","journal-title":"BJU Int"},{"key":"405_CR25","doi-asserted-by":"publisher","first-page":"e277","DOI":"10.1016\/S2214-109X(17)30058-X","volume":"5","author":"L Allen","year":"2017","unstructured":"Allen L, Williams J, Townsend N, Mikkelsen B, Roberts N, Foster C, et al. Socioeconomic status and non-communicable disease behavioural risk factors in low-income and lower-middle-income countries: a systematic review. Lancet Glob Health. 2017;5:e277\u2013e289.","journal-title":"Lancet Glob Health"},{"key":"405_CR26","first-page":"744","volume":"37","author":"N Campbell","year":"2021","unstructured":"Campbell N, Ordunez P, Giraldo G, Rodriguez Morales YA, Lombardi C, Khan T, et al. WHO HEARTS: a global program to reduce cardiovascular disease burden: experience implementing in the Americas and opportunities in Canada. Can J Cardiol. 2021;37:744\u201355.","journal-title":"Can J Cardiol"},{"key":"405_CR27","doi-asserted-by":"publisher","first-page":"2337","DOI":"10.1016\/S0140-6736(21)01169-7","volume":"397","author":"GBD 2019 Tobacco Collaborators.","year":"2021","unstructured":"GBD 2019 Tobacco Collaborators. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. Lancet. 2021;397:2337\u201360.","journal-title":"Lancet"},{"key":"405_CR28","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/s41581-019-0244-2","volume":"16","author":"KT Mills","year":"2020","unstructured":"Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nat Rev Nephrol. 2020;16:223\u201337.","journal-title":"Nat Rev Nephrol"},{"key":"405_CR29","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1038\/s41575-021-00457-x","volume":"18","author":"AP Klein","year":"2021","unstructured":"Klein AP. Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors. Nat Rev Gastroenterol Hepatol. 2021;18:493\u2013502.","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"405_CR30","doi-asserted-by":"publisher","first-page":"116450","DOI":"10.1016\/j.bcp.2024.116450","volume":"229","author":"S Ghareghomi","year":"2024","unstructured":"Ghareghomi S, Arghavani P, Mahdavi M, Khatibi A, Garc\u00eda-Jim\u00e9nez C, Moosavi-Movahedi AA. Hyperglycemia-driven signaling bridges between diabetes and cancer. Biochem Pharm. 2024;229:116450.","journal-title":"Biochem Pharm"},{"key":"405_CR31","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1016\/j.csbj.2021.03.003","volume":"19","author":"L Ismail","year":"2021","unstructured":"Ismail L, Materwala H, Al Kaabi J. Association of risk factors with type 2 diabetes: A systematic review. Comput Struct Biotechnol J. 2021;19:1759\u201385.","journal-title":"Comput Struct Biotechnol J"},{"key":"405_CR32","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1002\/cac2.12204","volume":"41","author":"J Yang","year":"2021","unstructured":"Yang J, Xu R, Wang C, Qiu J, Ren B, You L. Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review. Cancer Commun. 2021;41:1257\u201374.","journal-title":"Cancer Commun"},{"key":"405_CR33","doi-asserted-by":"publisher","first-page":"5837","DOI":"10.1002\/alz.13437","volume":"19","author":"JE Gaugler","year":"2023","unstructured":"Gaugler JE, Borson S, Epps F, Shih RA, Parker LJ, McGuire LC. The intersection of social determinants of health and family care of people living with Alzheimer\u2019s disease and related dementias: a public health opportunity. Alzheimers Dement. 2023;19:5837\u201346.","journal-title":"Alzheimers Dement"},{"key":"405_CR34","doi-asserted-by":"publisher","first-page":"4761","DOI":"10.1007\/s11357-024-01180-6","volume":"46","author":"X Cao","year":"2024","unstructured":"Cao X, Wang M, Zhou M, Mi Y, Fazekas-Pongor V, Major D, et al. Trends in prevalence, mortality, and risk factors of dementia among the oldest-old adults in the United States: the role of the obesity epidemic. Geroscience. 2024;46:4761\u201378.","journal-title":"Geroscience"},{"key":"405_CR35","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1017\/S1041610216001678","volume":"29","author":"R Fleming","year":"2017","unstructured":"Fleming R, Bennett K, Preece T, Phillipson L. The development and testing of the dementia friendly communities environment assessment tool (DFC EAT). Int Psychogeriatr. 2017;29:303\u201311.","journal-title":"Int Psychogeriatr"},{"key":"405_CR36","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1016\/S0140-6736(23)00001-6","volume":"401","author":"EW Gregg","year":"2023","unstructured":"Gregg EW, Buckley J, Ali MK, Davies J, Flood D, Mehta R, et al. Improving health outcomes of people with diabetes: target setting for the WHO global diabetes compact. Lancet. 2023;401:1302\u201312.","journal-title":"Lancet"},{"key":"405_CR37","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1002\/med.21883","volume":"42","author":"PR Pereira","year":"2022","unstructured":"Pereira PR, Carrageta DF, Oliveira PF, Rodrigues A, Alves MG, Monteiro MP. Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease. Med Res Rev. 2022;42:1518\u201344.","journal-title":"Med Res Rev"},{"key":"405_CR38","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1053\/j.ajkd.2021.05.023","volume":"79","author":"AJ Hahr","year":"2022","unstructured":"Hahr AJ, Molitch ME. Management of diabetes mellitus in patients with CKD: core curriculum 2022. Am J Kidney Dis. 2022;79:728\u201336.","journal-title":"Am J Kidney Dis"},{"key":"405_CR39","doi-asserted-by":"publisher","first-page":"1606","DOI":"10.1161\/CIR.0000000000001184","volume":"148","author":"CE Ndumele","year":"2023","unstructured":"Ndumele CE, Rangaswami J, Chow SL, Neeland IJ, Tuttle KR, Khan SS, et al. Cardiovascular-kidney-metabolic health: a presidential advisory from the American Heart Association. Circulation. 2023;148:1606\u201335.","journal-title":"Circulation"},{"key":"405_CR40","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.4103\/ijo.IJO_2804_21","volume":"70","author":"S Mannava","year":"2022","unstructured":"Mannava S, Borah RR, Shamanna BR. Current estimates of the economic burden of blindness and visual impairment in India: a cost of illness study. Indian J Ophthalmol. 2022;70:2141\u20135.","journal-title":"Indian J Ophthalmol"},{"key":"405_CR41","doi-asserted-by":"publisher","first-page":"1852","DOI":"10.1177\/11206721241238878","volume":"34","author":"C Zhao","year":"2024","unstructured":"Zhao C, Ding Q, Yang Z. Burdens and trends of blindness and vision loss among those aged 55 years and older: a systematic analysis for the Global Burden of Disease Study 2019. Eur J Ophthalmol. 2024;34:1852\u201364.","journal-title":"Eur J Ophthalmol"},{"key":"405_CR42","doi-asserted-by":"publisher","first-page":"e144","DOI":"10.1016\/S2214-109X(20)30489-7","volume":"9","author":"GBD 2019 Blindness and Vision Impairment Collaborators, Vision Loss Expert Group of the Global Burden of Disease Study.","year":"2021","unstructured":"GBD 2019 Blindness and Vision Impairment Collaborators, Vision Loss Expert Group of the Global Burden of Disease Study. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study. Lancet Glob Health. 2021;9:e144\u2013e160.","journal-title":"Lancet Glob Health"},{"key":"405_CR43","doi-asserted-by":"publisher","first-page":"e3073","DOI":"10.1002\/dmrr.3073","volume":"35","author":"JJ Drinkwater","year":"2019","unstructured":"Drinkwater JJ, Davis WA, Davis T. A systematic review of risk factors for cataract in type 2 diabetes. Diabetes Metab Res Rev. 2019;35:e3073.","journal-title":"Diabetes Metab Res Rev"},{"key":"405_CR44","doi-asserted-by":"publisher","first-page":"e091816","DOI":"10.1136\/bmjopen-2024-091816","volume":"15","author":"C Lin","year":"2025","unstructured":"Lin C, Jivraj S. Are diabetes and blood sugar control associated with the diagnosis of eye diseases? An English prospective observational study of glaucoma, diabetic eye disease, macular degeneration and cataract diagnosis trajectories in older age. BMJ Open. 2025;15:e091816.","journal-title":"BMJ Open"}],"container-title":["Nutrition & Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41387-025-00405-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41387-025-00405-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41387-025-00405-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T18:11:28Z","timestamp":1764180688000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41387-025-00405-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,24]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["405"],"URL":"https:\/\/doi.org\/10.1038\/s41387-025-00405-7","relation":{},"ISSN":["2044-4052"],"issn-type":[{"value":"2044-4052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,24]]},"assertion":[{"value":"9 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All participants in this study consented to publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Ethical approval and informed consent were not required for this study, as the analysis was based on the publicly available Global Burden of Disease (GBD) database, which contains no identifiable personal information.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"50"}}