{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T17:16:39Z","timestamp":1722791799536},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,10,18]],"date-time":"2020-10-18T00:00:00Z","timestamp":1602979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,18]],"date-time":"2020-10-18T00:00:00Z","timestamp":1602979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1038\/s41390-020-01204-9","type":"journal-article","created":{"date-parts":[[2020,10,18]],"date-time":"2020-10-18T10:02:37Z","timestamp":1603015357000},"page":"549-558","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chorioamnionitis induces changes in ovine pulmonary endogenous epithelial stem\/progenitor cells in utero"],"prefix":"10.1038","volume":"90","author":[{"given":"Helene","family":"Widowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daan R. M. G.","family":"Ophelders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana\u00efs J. C. N.","family":"van Leeuwen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter G. J.","family":"Nikkels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen A. H.","family":"Severens-Rijvers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa L. S.","family":"LaPointe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack P. M.","family":"Cleutjens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias C.","family":"H\u00fctten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew W.","family":"Kemp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew S.","family":"Payne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruo","family":"Usuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Newnham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan H.","family":"Jobe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris W.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tammo","family":"Delhaas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim G. A. M.","family":"Wolfs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niki L.","family":"Reynaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,10,18]]},"reference":[{"key":"1204_CR1","doi-asserted-by":"crossref","unstructured":"Sabic, D. & Koenig, J. M. A perfect storm: fetal inflammation and the developing immune system. Pediatr. Res. 87, 319\u2013326 (2019).","DOI":"10.1038\/s41390-019-0582-6"},{"key":"1204_CR2","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.pedneo.2017.09.001","volume":"59","author":"CC Peng","year":"2018","unstructured":"Peng, C. C. et al. Intrauterine inflammation, infection, or both (Triple I): a new concept for chorioamnionitis. Pediatr. Neonatol. 59, 231\u2013237 (2018).","journal-title":"Pediatr. Neonatol."},{"key":"1204_CR3","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1515\/JPM.2003.016","volume":"31","author":"A Berger","year":"2003","unstructured":"Berger, A. et al. Microbial invasion of the amniotic cavity at birth is associated with adverse short-term outcome of preterm infants. J. Perinat. Med. 31, 115\u2013121 (2003).","journal-title":"J. Perinat. Med."},{"key":"1204_CR4","doi-asserted-by":"publisher","first-page":"412831","DOI":"10.1155\/2013\/412831","volume":"2013","author":"R Galinsky","year":"2013","unstructured":"Galinsky, R. et al. The consequences of chorioamnionitis: preterm birth and effects on development. J. Pregnancy 2013, 412831 (2013).","journal-title":"J. Pregnancy"},{"key":"1204_CR5","first-page":"49","volume":"15","author":"W Thomas","year":"2014","unstructured":"Thomas, W. & Speer, C. P. Chorioamnionitis is essential in the evolution of bronchopulmonary dysplasia\u2013the case in favour. Paediatr. Respir. Rev. 15, 49\u201352 (2014).","journal-title":"Paediatr. Respir. Rev."},{"key":"1204_CR6","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.jpeds.2017.08.041","volume":"190","author":"CM Alvira","year":"2017","unstructured":"Alvira, C. M. & Morty, R. E. Can we understand the pathobiology of bronchopulmonary dysplasia? J. Pediatr. 190, 27\u201337 (2017).","journal-title":"J. Pediatr."},{"key":"1204_CR7","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/j.chest.2017.04.173","volume":"152","author":"MA M\u00f6bius","year":"2017","unstructured":"M\u00f6bius, M. A. & Th\u00e9baud, B. Bronchopulmonary dysplasia: where have all the stem cells gone?: origin and (potential) function of resident lung stem cells. Chest 152, 1043\u20131052 (2017).","journal-title":"Chest"},{"key":"1204_CR8","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1002\/bdra.23227","volume":"100","author":"JJ Collins","year":"2014","unstructured":"Collins, J. J. & Thebaud, B. Progenitor cells of the distal lung and their potential role in neonatal lung disease. Birth Defects Res. A Clin. Mol. Teratol. 100, 217\u2013226 (2014).","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"1204_CR9","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1177\/44.7.8675988","volume":"44","author":"MT Stahlman","year":"1996","unstructured":"Stahlman, M. T., Gray, M. E. & Whitsett, J. A. Expression of thyroid transcription factor-1 (TTF-1) in fetal and neonatal human lung. J. Histochem. Cytochem. 44, 673\u2013678 (1996).","journal-title":"J. Histochem. Cytochem."},{"key":"1204_CR10","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1165\/rcmb.2016-0150OC","volume":"56","author":"M Yee","year":"2017","unstructured":"Yee, M. et al. Alternative progenitor lineages regenerate the adult lung depleted of alveolar epithelial type 2 cells. Am. J. Respir. Cell Mol. Biol. 56, 453\u2013464 (2017).","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"1204_CR11","doi-asserted-by":"publisher","first-page":"334","DOI":"10.4103\/IJPM.IJPM_650_17","volume":"61","author":"I Das","year":"2018","unstructured":"Das, I. et al. A study of spectrum of pulmonary pathology and expression of thyroid transcription factor-1 during neonatal period. Indian J. Pathol. Microbiol. 61, 334\u2013338 (2018).","journal-title":"Indian J. Pathol. Microbiol."},{"key":"1204_CR12","doi-asserted-by":"publisher","first-page":"e0180114","DOI":"10.1371\/journal.pone.0180114","volume":"12","author":"MG Willems","year":"2017","unstructured":"Willems, M. G. et al. Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide. PLoS ONE 12, e0180114 (2017).","journal-title":"PLoS ONE"},{"key":"1204_CR13","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/pr.2013.226","volume":"75","author":"E Kuypers","year":"2014","unstructured":"Kuypers, E. et al. Altered canonical Wingless-Int signaling in the ovine fetal lung after exposure to intra-amniotic lipopolysaccharide and antenatal betamethasone. Pediatr. Res. 75, 281\u2013287 (2014).","journal-title":"Pediatr. Res."},{"key":"1204_CR14","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1159\/000479021","volume":"39","author":"R Gussenhoven","year":"2017","unstructured":"Gussenhoven, R. et al. The paradoxical effects of chronic intra-amniotic Ureaplasma parvum exposure on ovine fetal brain development. Dev. Neurosci. 39, 472\u2013486 (2017).","journal-title":"Dev. Neurosci."},{"key":"1204_CR15","doi-asserted-by":"publisher","first-page":"L1","DOI":"10.1152\/ajplung.00289.2015","volume":"310","author":"MG Willems","year":"2016","unstructured":"Willems, M. G. et al. Systemic interleukin-2 administration improves lung function and modulates chorioamnionitis-induced pulmonary inflammation in the ovine fetus. Am. J. Physiol. Lung Cell. Mol. Physiol. 310, L1\u2013L7 (2016).","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"1204_CR16","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3389\/fped.2016.00036","volume":"4","author":"S Leibel","year":"2016","unstructured":"Leibel, S. & Post, M. Endogenous and exogenous stem\/progenitor cells in the lung and their role in the pathogenesis and treatment of pediatric lung disease. Front. Pediatr. 4, 36 (2016).","journal-title":"Front. Pediatr."},{"key":"1204_CR17","unstructured":"Peake, J. L. & Pinkerton, K. E. in Comparative Biology of the Normal Lung (ed. Parent, R. A.) Ch. 3 (Elsevier, 2015)."},{"key":"1204_CR18","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1038\/nature14112","volume":"517","author":"AE Vaughan","year":"2015","unstructured":"Vaughan, A. E. et al. Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury. Nature 517, 621\u2013625 (2015).","journal-title":"Nature"},{"key":"1204_CR19","doi-asserted-by":"publisher","first-page":"L144","DOI":"10.1152\/ajplung.00379.2017","volume":"314","author":"S Danopoulos","year":"2018","unstructured":"Danopoulos, S. et al. Human lung branching morphogenesis is orchestrated by the spatiotemporal distribution of ACTA2, SOX2, and SOX9. Am. J. Physiol. Lung Cell. Mol. Physiol. 314, L144\u2013L149 (2018).","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"1204_CR20","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1017\/S2040174417000733","volume":"8","author":"T Bianco-Miotto","year":"2017","unstructured":"Bianco-Miotto, T. et al. Epigenetics and DOHaD: from basics to birth and beyond. J. Dev. Orig. Health Dis. 8, 513\u2013519 (2017).","journal-title":"J. Dev. Orig. Health Dis."},{"key":"1204_CR21","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1016\/S0140-6736(14)60446-3","volume":"385","author":"DS Postma","year":"2015","unstructured":"Postma, D. S., Bush, A. & van den Berge, M. Risk factors and early origins of chronic obstructive pulmonary disease. Lancet 385, 899\u2013909 (2015).","journal-title":"Lancet"},{"key":"1204_CR22","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/s12931-019-1075-1","volume":"20","author":"P Um-Bergstrom","year":"2019","unstructured":"Um-Bergstrom, P. et al. Pulmonary outcomes in adults with a history of bronchopulmonary dysplasia differ from patients with asthma. Respir. Res. 20, 102 (2019).","journal-title":"Respir. Res."},{"key":"1204_CR23","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1164\/rccm.200812-1949OC","volume":"180","author":"A Borghesi","year":"2009","unstructured":"Borghesi, A. et al. Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia. Am. J. Respir. Crit. Care Med. 180, 540\u2013546 (2009).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"1204_CR24","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1007\/s00441-016-2545-0","volume":"367","author":"JC Schittny","year":"2017","unstructured":"Schittny, J. C. Development of the lung. Cell Tissue Res. 367, 427\u2013444 (2017).","journal-title":"Cell Tissue Res."},{"key":"1204_CR25","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1164\/ajrccm\/150.5_Pt_2.S27","volume":"150","author":"SI Rennard","year":"1994","unstructured":"Rennard, S. I. et al. Airway epithelial cells: functional roles in airway disease. Am. J. Respir. Crit. Care Med. 150, S27\u2013S30 (1994).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"1204_CR26","doi-asserted-by":"publisher","first-page":"S244","DOI":"10.1513\/AnnalsATS.201407-304AW","volume":"11","author":"DE Davies","year":"2014","unstructured":"Davies, D. E. Epithelial barrier function and immunity in asthma. Ann. Am. Thorac. Soc. 11, S244\u2013S251 (2014).","journal-title":"Ann. Am. Thorac. Soc."},{"key":"1204_CR27","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12861-015-0082-9","volume":"15","author":"ML Donne","year":"2015","unstructured":"Donne, M. L., Lechner, A. J. & Rock, J. R. Evidence for lung epithelial stem cell niches. BMC Dev. Biol. 15, 32 (2015).","journal-title":"BMC Dev. Biol."},{"key":"1204_CR28","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s40348-016-0062-6","volume":"3","author":"C Ota","year":"2016","unstructured":"Ota, C. et al. Linking bronchopulmonary dysplasia to adult chronic lung diseases: role of WNT signaling. Mol. Cell Pediatr. 3, 34 (2016).","journal-title":"Mol. Cell Pediatr."},{"key":"1204_CR29","doi-asserted-by":"crossref","unstructured":"Saito, A., Horie, M. & Nagase, T. TGF-beta signaling in lung health and disease. Int. J. Mol. Sci. 19, 2460 (2018).","DOI":"10.3390\/ijms19082460"},{"key":"1204_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5493\/wjem.v7.i1.1","volume":"7","author":"AS Ahmed","year":"2017","unstructured":"Ahmed, A. S. et al. Effect of aging on stem cells. World J. Exp. Med. 7, 1\u201310 (2017).","journal-title":"World J. Exp. Med."},{"key":"1204_CR31","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s40348-016-0052-8","volume":"3","author":"S Meiners","year":"2016","unstructured":"Meiners, S. & Hilgendorff, A. Early injury of the neonatal lung contributes to premature lung aging: a hypothesis. Mol. Cell. Pediatr. 3, 24 (2016).","journal-title":"Mol. Cell. Pediatr."},{"key":"1204_CR32","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1164\/ajrccm.163.7.2011060","volume":"163","author":"AH Jobe","year":"2001","unstructured":"Jobe, A. H. & Bancalari, E. Bronchopulmonary dysplasia. Am. J. Respir. Crit. Care Med. 163, 1723\u20131729 (2001).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"1204_CR33","doi-asserted-by":"publisher","first-page":"143","DOI":"10.2350\/10-05-0112.1","volume":"9","author":"R Viscardi","year":"2006","unstructured":"Viscardi, R. et al. Disordered pulmonary myofibroblast distribution and elastin expression in preterm infants with Ureaplasma urealyticum pneumonitis. Pediatr. Dev. Pathol. 9, 143\u2013151 (2006).","journal-title":"Pediatr. Dev. Pathol."},{"key":"1204_CR34","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/pr.2015.224","volume":"79","author":"CW Choi","year":"2016","unstructured":"Choi, C. W. et al. Protective effect of chorioamnionitis on the development of bronchopulmonary dysplasia triggered by postnatal systemic inflammation in neonatal rats. Pediatr. Res. 79, 287\u2013294 (2016).","journal-title":"Pediatr. Res."},{"key":"1204_CR35","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1203\/00006450-200012000-00014","volume":"48","author":"KE Willet","year":"2000","unstructured":"Willet, K. E. et al. Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs. Pediatr. Res. 48, 782\u2013788 (2000).","journal-title":"Pediatr. Res."},{"key":"1204_CR36","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1165\/rcmb.2013-0207OC","volume":"50","author":"M Yee","year":"2014","unstructured":"Yee, M., Buczynski, B. W. & O\u2019Reilly, M. A. Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells. Am. J. Respir. Cell Mol. Biol. 50, 757\u2013766 (2014).","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"1204_CR37","doi-asserted-by":"publisher","first-page":"L1101","DOI":"10.1152\/ajplung.00126.2006","volume":"291","author":"M Yee","year":"2006","unstructured":"Yee, M. et al. Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L1101\u2013L1111 (2006).","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"1204_CR38","doi-asserted-by":"publisher","first-page":"L412","DOI":"10.1152\/ajplung.00181.2016","volume":"311","author":"N Deptula","year":"2016","unstructured":"Deptula, N. et al. Brief mechanical ventilation causes differential epithelial repair along the airways of fetal, preterm lambs. Am. J. Physiol. Lung Cell. Mol. Physiol. 311, L412\u2013L420 (2016).","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"1204_CR39","first-page":"240","volume":"22","author":"M Kemp","year":"2015","unstructured":"Kemp, M. et al. The clinical use of corticosteroids in pregnancy. Hum. Reprod. Update 22, 240\u2013259 (2015).","journal-title":"Hum. Reprod. Update"},{"key":"1204_CR40","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1159\/000381117","volume":"107","author":"T Curstedt","year":"2015","unstructured":"Curstedt, T., Halliday, H. L. & Speer, C. P. A unique story in neonatal research: the development of a porcine surfactant. Neonatology 107, 321\u2013329 (2015).","journal-title":"Neonatology"}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41390-020-01204-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-020-01204-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-020-01204-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T23:27:03Z","timestamp":1634513223000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41390-020-01204-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,18]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["1204"],"URL":"https:\/\/doi.org\/10.1038\/s41390-020-01204-9","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,18]]},"assertion":[{"value":"1 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"No patient consent was required for this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient consent"}}]}}