{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:27:31Z","timestamp":1791473251611,"version":"4.3.4"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1038\/s41390-024-03466-z","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T15:02:08Z","timestamp":1723302128000},"page":"1220-1226","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Perinatal hypoxia augments contractile impact of NADPH oxidase-derived ROS in early postnatal rat arteries"],"prefix":"10.1038","volume":"97","author":[{"given":"Valentina S.","family":"Shateeva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia D.","family":"Simonenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita A.","family":"Khlystova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina K.","family":"Selivanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna A.","family":"Borzykh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina K.","family":"Gaynullina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia A.","family":"Shvetsova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,10]]},"reference":[{"key":"3466_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms20061421","volume":"20","author":"DK Gaynullina","year":"2019","unstructured":"Gaynullina, D. K., Schubert, R. & Tarasova, O. S. Changes in endothelial nitric oxide production in systemic vessels during early ontogenesis\u2014A key mechanism for the perinatal adaptation of the circulatory system. Int. J. Mol. Sci. 20, 1\u201312 (2019).","journal-title":"Int. J. Mol. Sci."},{"key":"3466_CR2","doi-asserted-by":"publisher","first-page":"5413","DOI":"10.3390\/ijms22115413","volume":"22","author":"AA Shvetsova","year":"2021","unstructured":"Shvetsova, A. A., Gaynullina, D. K., Tarasova, O. S. & Schubert, R. Remodeling of arterial tone regulation in postnatal development: focus on smooth muscle cell potassium channels. Int. J. Mol. Sci. 22, 5413 (2021).","journal-title":"Int. J. Mol. Sci."},{"key":"3466_CR3","doi-asserted-by":"publisher","first-page":"2210","DOI":"10.1134\/S0022093023060248","volume":"59","author":"AA Shvetsova","year":"2023","unstructured":"Shvetsova, A. A., Gaynullina, D. K. & Tarasova, O. S. The role of reactive oxygen species in the regulation of blood vessel tone in perinatal and early postnatal ontogenesis. J. Evol. Biochem. Physiol. 59, 2210\u20132227 (2023).","journal-title":"J. Evol. Biochem. Physiol."},{"key":"3466_CR4","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1038\/sj.bjp.0702217","volume":"125","author":"I Morecroft","year":"1998","unstructured":"Morecroft, I. & MacLean, M. R. Developmental changes in endothelium-dependent vasodilation and the influence of superoxide anions in perinatal rabbit pulmonary arteries. Br. J. Pharmacol. 125, 1585\u20131593 (1998).","journal-title":"Br. J. Pharmacol."},{"key":"3466_CR5","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1016\/j.freeradbiomed.2004.07.029","volume":"37","author":"J Belik","year":"2004","unstructured":"Belik, J., Jankov, R. P., Pan, J. & Tanswell, A. K. Peroxynitrite inhibits relaxation and induces pulmonary artery muscle contraction in the newborn rat. Free Radic. Biol. Med. 37, 1384\u20131392 (2004).","journal-title":"Free Radic. Biol. Med."},{"key":"3466_CR6","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.freeradbiomed.2024.03.005","volume":"216","author":"AA Shvetsova","year":"2024","unstructured":"Shvetsova, A. A. et al. Reactive oxygen species augment contractile responses of saphenous artery in 10-15-day-old but not adult rats: Substantial role of NADPH oxidases. Free Radic. Biol. Med. 216, 24\u201332 (2024).","journal-title":"Free Radic. Biol. Med."},{"key":"3466_CR7","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.freeradbiomed.2019.09.029","volume":"145","author":"GA Knock","year":"2019","unstructured":"Knock, G. A. NADPH oxidase in the vasculature: expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension. Free Radic. Biol. Med. 145, 385\u2013427 (2019).","journal-title":"Free Radic. Biol. Med."},{"key":"3466_CR8","doi-asserted-by":"crossref","unstructured":"Shvetsova, A. A. et al. Perinatal hypoxia weakens anticontractile influence of NO in rat arteries during early postnatal period. Pediatr. Res. 95, 1758\u20131763 (2024).","DOI":"10.1038\/s41390-024-03062-1"},{"key":"3466_CR9","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1152\/ajplung.90568.2008","volume":"297","author":"KE Dennis","year":"2009","unstructured":"Dennis, K. E. et al. NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets. Am. J. Physiol. Lung Cell. Mol. Physiol. 297, 596\u2013607 (2009).","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"3466_CR10","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.reprotox.2016.01.001","volume":"60","author":"X Zhu","year":"2016","unstructured":"Zhu, X. et al. Prenatal hypoxia enhanced angiotensin II-mediated vasoconstriction via increased oxidative signaling in fetal rats. Reprod. Toxicol. 60, 21\u201328 (2016).","journal-title":"Reprod. Toxicol."},{"key":"3466_CR11","first-page":"1","volume":"14","author":"M Ortiz","year":"2022","unstructured":"Ortiz, M., Loidl, F. & V\u00e1zquez-Borsetti, P. Transition to extrauterine life and the modeling of perinatal asphyxia in rats. WIREs Mech. Dis. 14, 1\u201316 (2022).","journal-title":"WIREs Mech. Dis."},{"key":"3466_CR12","doi-asserted-by":"publisher","first-page":"28","DOI":"10.2478\/v10102-009-0005-3","volume":"2","author":"M Mach","year":"2009","unstructured":"Mach, M., Dubovick\u00fd, M., Navarov\u00e1, J., Brucknerov\u00e1, I. & Ujh\u00e1zy, E. Experimental modeling of hypoxia in pregnancy and early postnatal life. Interdiscip. Toxicol. 2, 28\u201332 (2009).","journal-title":"Interdiscip. Toxicol."},{"key":"3466_CR13","doi-asserted-by":"publisher","first-page":"67","DOI":"10.5409\/wjcp.v5.i1.67","volume":"5","author":"CE Ahearne","year":"2016","unstructured":"Ahearne, C. E. Short and long term prognosis in perinatal asphyxia: an update. World J. Clin. Pediatr. 5, 67 (2016).","journal-title":"World J. Clin. Pediatr."},{"key":"3466_CR14","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.clp.2016.04.002","volume":"43","author":"MA Rainaldi","year":"2016","unstructured":"Rainaldi, M. A. & Perlman, J. M. Pathophysiology of birth asphyxia. Clin. Perinatol. 43, 409\u2013422 (2016).","journal-title":"Clin. Perinatol."},{"key":"3466_CR15","first-page":"43","volume":"2","author":"X Yang","year":"2012","unstructured":"Yang, X., Salminen, W. F. & Schnackenberg, L. K. Current and emerging biomarkers of hepatotoxicity. Curr. Biomarler Find. 2, 43\u201355 (2012).","journal-title":"Curr. Biomarler Find."},{"key":"3466_CR16","unstructured":"Blank, M. et al. Review of Qualification Data for Biomarkers of Nephrotoxicity Submitted by the Predictive Safety Testing Consortium. (2009)."},{"key":"3466_CR17","doi-asserted-by":"publisher","unstructured":"Arndt, T. P. & Boone, L. I. Clinical Pathology of the Rat. The Laboratory Rat 3rd edn https:\/\/doi.org\/10.1016\/B978-0-12-814338-4.00005-2 (Elsevier Inc., 2020).","DOI":"10.1016\/B978-0-12-814338-4.00005-2"},{"key":"3466_CR18","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1159\/000241004","volume":"32","author":"B \u0160tulcov\u00e1","year":"1977","unstructured":"\u0160tulcov\u00e1, B. Postnatal development of cardiac output distribution measured by radioactive microspheres in rats. Neonatology 32, 119\u2013124 (1977).","journal-title":"Neonatology"},{"key":"3466_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.niox.2016.02.005","volume":"55\u201356","author":"SI Sofronova","year":"2016","unstructured":"Sofronova, S. I. et al. Endothelial nitric oxide weakens arterial contractile responses and reduces blood pressure during early postnatal development in rats. Nitric Oxide 55\u201356, 1\u20139 (2016).","journal-title":"Nitric Oxide"},{"key":"3466_CR20","doi-asserted-by":"publisher","first-page":"e13044","DOI":"10.1111\/apha.13044","volume":"12","author":"SV Mochalov","year":"2018","unstructured":"Mochalov, S. V. et al. Higher Ca2+-sensitivity of arterial contraction in 1-week-old rats is due to a greater Rho-kinase activity. Acta Physiol. 12, e13044 (2018).","journal-title":"Acta Physiol."},{"key":"3466_CR21","doi-asserted-by":"publisher","first-page":"5148","DOI":"10.1111\/bph.15249","volume":"177","author":"AA Shvetsova","year":"2020","unstructured":"Shvetsova, A. A. et al. TASK\u20101 channel blockade by AVE1231 increases vasocontractile responses and BP in 1\u2010 to 2\u2010week\u2010old but not adult rats. Br. J. Pharmacol. 177, 5148\u20135162 (2020).","journal-title":"Br. J. Pharmacol."},{"key":"3466_CR22","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1161\/01.RES.41.1.19","volume":"41","author":"MJ Mulvany","year":"1977","unstructured":"Mulvany, M. J. & Halpern, W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ. Res. 41, 19\u201326 (1977).","journal-title":"Circ. Res."},{"key":"3466_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fphys.2022.1003073","volume":"13","author":"AA Borzykh","year":"2022","unstructured":"Borzykh, A. A. et al. Voluntary wheel exercise training affects locomotor muscle, but not the diaphragm in the rat. Front. Physiol. 13, 1\u201314 (2022).","journal-title":"Front. Physiol."},{"key":"3466_CR24","doi-asserted-by":"publisher","first-page":"2361","DOI":"10.1111\/bph.16087","volume":"180","author":"MA Olivencia","year":"2023","unstructured":"Olivencia, M. A. et al. Oxidized soluble guanylyl cyclase causes erectile dysfunction in alcoholic mice. Br. J. Pharmacol. 180, 2361\u20132376 (2023).","journal-title":"Br. J. Pharmacol."},{"key":"3466_CR25","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/1750-1326-8-44","volume":"8","author":"M Oliveras-Salv\u00e1","year":"2013","unstructured":"Oliveras-Salv\u00e1, M. et al. rAAV2\/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration. Mol. Neurodegener. 8, 44 (2013).","journal-title":"Mol. Neurodegener."},{"key":"3466_CR26","doi-asserted-by":"publisher","first-page":"372","DOI":"10.3389\/fnins.2020.00372","volume":"14","author":"I Piano","year":"2020","unstructured":"Piano, I. et al. Myriocin effect on Tvrm4 retina, an autosomal dominant pattern of retinitis pigmentosa. Front. Neurosci. 14, 372 (2020).","journal-title":"Front. Neurosci."},{"key":"3466_CR27","first-page":"1734","volume":"18","author":"B-Y Ding","year":"2022","unstructured":"Ding, B.-Y. et al. Knockdown of NADPH oxidase 4 reduces mitochondrial oxidative stress and neuronal pyroptosis following intracerebral hemorrhage. Neural Regen. Res. 18, 1734\u20131742 (2022).","journal-title":"Neural Regen. Res."},{"key":"3466_CR28","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.neuro.2016.02.010","volume":"53","author":"GA Wiggers","year":"2016","unstructured":"Wiggers, G. A. et al. Cerebrovascular endothelial dysfunction induced by mercury exposure at low concentrations. Neurotoxicology 53, 282\u2013289 (2016).","journal-title":"Neurotoxicology"},{"key":"3466_CR29","doi-asserted-by":"publisher","first-page":"2605","DOI":"10.1016\/j.celrep.2018.11.015","volume":"25","author":"S Zemanovic","year":"2018","unstructured":"Zemanovic, S. et al. Dynamic phosphorylation of the C terminus of Hsp70 regulates the mitochondrial import of SOD2 and redox balance. Cell Rep. 25, 2605\u20132616 (2018).","journal-title":"Cell Rep."},{"key":"3466_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms222413629","volume":"22","author":"O Gutziet","year":"2021","unstructured":"Gutziet, O. et al. Maternal N-acetyl-cysteine prevents neonatal hypoxia-induced brain injury in a rat model. Int. J. Mol. Sci. 22, 1\u201312 (2021).","journal-title":"Int. J. Mol. Sci."},{"key":"3466_CR31","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.bbr.2018.05.008","volume":"350","author":"IA Sukhanova","year":"2018","unstructured":"Sukhanova, I. A. et al. Gender-dependent changes in physical development, BDNF content and GSH redox system in a model of acute neonatal hypoxia in rats. Behav. Brain Res. 350, 87\u201398 (2018).","journal-title":"Behav. Brain Res."},{"key":"3466_CR32","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.ijdevneu.2019.06.007","volume":"78","author":"IA Sukhanova","year":"2019","unstructured":"Sukhanova, I. A. et al. Early-life N-arachidonoyl-dopamine exposure increases antioxidant capacity of the brain tissues and reduces functional deficits after neonatal hypoxia in rats. Int. J. Dev. Neurosci. 78, 7\u201318 (2019).","journal-title":"Int. J. Dev. Neurosci."},{"key":"3466_CR33","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.1152\/ajpregu.00909.2006","volume":"292","author":"EA Herrera","year":"2007","unstructured":"Herrera, E. A. et al. High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, 2234\u20132240 (2007).","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"3466_CR34","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1152\/ajpregu.00178.2004","volume":"288","author":"SJ Williams","year":"2005","unstructured":"Williams, S. J., Campbell, M. E., Mcmillen, I. C. & Davidge, S. T. Differential effects of maternal hypoxia or nutrient restriction on carotid and femoral vascular function in neonatal rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288, 360\u2013367 (2005).","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"3466_CR35","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.3389\/fphys.2019.01032","volume":"10","author":"D Moretta","year":"2019","unstructured":"Moretta, D. et al. Long-term high-altitude hypoxia and alpha adrenoceptor-dependent pulmonary arterial contractions in fetal and adult sheep. Front. Physiol. 10, 1032 (2019).","journal-title":"Front. Physiol."},{"key":"3466_CR36","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1177\/1933719109333439","volume":"16","author":"RD Gilbert","year":"2009","unstructured":"Gilbert, R. D., Maruko, K. & Stiffel, V. M. The effect of long-term hypoxia on tension and intracellular calcium responses following stimulation of the thromboxane A2 receptor in the left anterior descending coronary artery of fetal sheep. Reprod. Sci. 16, 364\u2013372 (2009).","journal-title":"Reprod. Sci."},{"key":"3466_CR37","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1177\/107155760000700304","volume":"7","author":"FC Garcia","year":"2000","unstructured":"Garcia, F. C., Stiffel, V. M., Pearce, W. J., Zhang, L. & Gilbert, R. D. Ca(2+) sensitivity of fetal coronary arteries exposed to long-term, high-altitude hypoxia. J. Soc. Gynecol. Investig. 7, 161\u2013166 (2000).","journal-title":"J. Soc. Gynecol. Investig."},{"key":"3466_CR38","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1152\/japplphysiol.01110.2001","volume":"92","author":"WEN Long","year":"2002","unstructured":"Long, W. E. N., Zhang, L. & Longo, L. D. Fetal and adult cerebral artery K ATP and K Ca channel responses to long-term hypoxia. J. Appl. Physiol. 92, 1692\u20131701 (2002).","journal-title":"J. Appl. Physiol."},{"key":"3466_CR39","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1134\/S0022093023030134","volume":"59","author":"AA Shvetsova","year":"2023","unstructured":"Shvetsova, A. A. et al. Vascular effects of perinatal hypoxia in the early postnatal period in rats. J. Evol. Biochem. Physiol. 59, 800\u2013808 (2023).","journal-title":"J. Evol. Biochem. Physiol."},{"key":"3466_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1423-0127-17-67","volume":"17","author":"MH Tsai","year":"2010","unstructured":"Tsai, M. H. & Jiang, M. J. Reactive oxygen species are involved in regulating \u03b11- adrenoceptor-activated vascular smooth muscle contraction. J. Biomed. Sci. 17, 1\u201310 (2010).","journal-title":"J. Biomed. Sci."},{"key":"3466_CR41","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.abb.2009.05.015","volume":"487","author":"S Chakraborti","year":"2009","unstructured":"Chakraborti, S. et al. Role of protein kinase C in NADPH oxidase derived O2 -mediated regulation of Kv \u2013 LVOCC axis under U46619 induced increase in [Ca2+] i in pulmonary smooth muscle cells. Arch. Biochem. Biophys. 487, 123\u2013130 (2009).","journal-title":"Arch. Biochem. Biophys."},{"key":"3466_CR42","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1152\/ajpheart.00491.2008","volume":"296","author":"SA Gupte","year":"2009","unstructured":"Gupte, S. A. et al. Peroxide generation by p47 phox -Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction. Am. J. Physiol. Hear. Circ. Physiol. 296, 1048\u20131057 (2009).","journal-title":"Am. J. Physiol. Hear. Circ. Physiol."},{"key":"3466_CR43","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.redox.2013.12.002","volume":"2","author":"AU Rehman","year":"2014","unstructured":"Rehman, A. U., Dugic, E., Benham, C., Lione, L. & Mackenzie, L. S. Selective inhibition of NADPH oxidase reverses the over contraction of diabetic rat aorta. Redox Biol. 2, 61\u201364 (2014).","journal-title":"Redox Biol."},{"key":"3466_CR44","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1093\/cvr\/cvq275","volume":"89","author":"VA Snetkov","year":"2011","unstructured":"Snetkov, V. A. et al. Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways. Cardiovasc. Res. 89, 214\u2013224 (2011).","journal-title":"Cardiovasc. Res."},{"key":"3466_CR45","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.freeradbiomed.2008.11.015","volume":"46","author":"GA Knock","year":"2009","unstructured":"Knock, G. A. et al. Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca2+ sensitization. Free Radic. Biol. Med. 46, 633\u2013642 (2009).","journal-title":"Free Radic. Biol. Med."},{"key":"3466_CR46","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1152\/physrev.00023.2003","volume":"83","author":"AP Somlyo","year":"2003","unstructured":"Somlyo, A. P. & Somlyo, A. V. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol. Rev. 83, 1325\u20131358 (2003).","journal-title":"Physiol. Rev."},{"key":"3466_CR47","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1161\/hh1201.092035","volume":"88","author":"K Nobe","year":"2001","unstructured":"Nobe, K. & Paul, R. J. Effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca2+. Circ. Res. 88, 1283\u20131290 (2001).","journal-title":"Circ. Res."}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41390-024-03466-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-024-03466-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-024-03466-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:02:47Z","timestamp":1747227767000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41390-024-03466-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,10]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["3466"],"URL":"https:\/\/doi.org\/10.1038\/s41390-024-03466-z","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,10]]},"assertion":[{"value":"2 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 July 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}