{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T11:57:56Z","timestamp":1793447876373,"version":"4.5.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T00:00:00Z","timestamp":1736899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T00:00:00Z","timestamp":1736899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1038\/s41390-025-03820-9","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T08:36:10Z","timestamp":1736930170000},"page":"498-506","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Beneficial vs harmful effects of pharmacological treatment of patent ductus arteriosus: A Bayesian meta-analysis"],"prefix":"10.1038","volume":"98","author":[{"given":"Eduardo","family":"Villamor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Gal\u00e1n-Henr\u00edquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franti\u0161ek","family":"Barto\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gema E.","family":"Gonzalez-Luis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,15]]},"reference":[{"key":"3820_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113532","volume":"261","author":"MB Liguori","year":"2023","unstructured":"Liguori, M. B. et al. Patent Ductus Arteriosus in premature infants: clinical trials and Equipoise. J. Pediatr. 261, 113532, https:\/\/doi.org\/10.1016\/j.jpeds.2023.113532 (2023).","journal-title":"J. Pediatr."},{"key":"3820_CR2","doi-asserted-by":"publisher","first-page":"F498","DOI":"10.1136\/adc.2005.092734","volume":"92","author":"CL Bose","year":"2007","unstructured":"Bose, C. L. & Laughon, M. M. Patent ductus arteriosus: lack of evidence for common treatments. Arch. Dis. Child Fetal Neonatal Ed. 92, F498\u2013F502, https:\/\/doi.org\/10.1136\/adc.2005.092734 (2007).","journal-title":"Arch. Dis. Child Fetal Neonatal Ed."},{"key":"3820_CR3","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/j.siny.2015.03.004","volume":"20","author":"N Evans","year":"2015","unstructured":"Evans, N. Preterm patent ductus arteriosus: a continuing conundrum for the neonatologist? Semin Fetal Neonatal Med. 20, 272\u2013277, https:\/\/doi.org\/10.1016\/j.siny.2015.03.004 (2015).","journal-title":"Semin Fetal Neonatal Med."},{"key":"3820_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2021.101219","volume":"26","author":"K de Waal","year":"2021","unstructured":"de Waal, K., Prasad, R. & Kluckow, M. Patent ductus arteriosus management and the drift towards therapeutic nihilism\u2013What is the evidence? Semin. Fetal Neonatal Med. 26, 101219, https:\/\/doi.org\/10.1016\/j.siny.2021.101219 (2021).","journal-title":"Semin. Fetal Neonatal Med."},{"key":"3820_CR5","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013588.pub2","volume":"4","author":"S Mitra","year":"2023","unstructured":"Mitra, S., de Boode, W. P., Weisz DE & Shah, P. S. Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews. Cochrane Database Syst. Rev. 4, CD013588, https:\/\/doi.org\/10.1002\/14651858.CD013588.pub2 (2023).","journal-title":"Cochrane Database Syst. Rev."},{"key":"3820_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113877","volume":"266","author":"DC Kaluarachchi","year":"2024","unstructured":"Kaluarachchi, D. C. et al. Secular trends in patent Ductus Arteriosus management in infants born preterm in the National Institute of Child Health and Human Development Neonatal Research Network. J. Pediatr. 266, 113877, https:\/\/doi.org\/10.1016\/j.jpeds.2023.113877 (2024).","journal-title":"J. Pediatr."},{"key":"3820_CR7","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1056\/NEJMoa2207418","volume":"388","author":"T Hundscheid","year":"2023","unstructured":"Hundscheid, T. et al. Expectant management or early ibuprofen for patent ductus arteriosus. N. Engl. J. Med 388, 980\u2013990, https:\/\/doi.org\/10.1056\/NEJMoa2207418 (2023).","journal-title":"N. Engl. J. Med"},{"key":"3820_CR8","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1055\/a-1782-5860","volume":"41","author":"S Potsiurko","year":"2024","unstructured":"Potsiurko, S., Dobryanskyy, D., Sekretar, L. & Salabay, Z. Randomized noninferiority trial of expectant management versus early treatment of patent ductus arteriosus in preterm infants. Am. J. Perinatol. 41, 730\u2013738, https:\/\/doi.org\/10.1055\/a-1782-5860 (2024).","journal-title":"Am. J. Perinatol."},{"key":"3820_CR9","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1056\/NEJMoa2305582","volume":"390","author":"S Gupta","year":"2024","unstructured":"Gupta, S. et al. Trial of selective early treatment of patent ductus arteriosus with ibuprofen. N. Engl. J. Med 390, 314\u2013325, https:\/\/doi.org\/10.1056\/NEJMoa2305582 (2024).","journal-title":"N. Engl. J. Med"},{"key":"3820_CR10","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.jpeds.2020.08.062","volume":"228","author":"K de Waal","year":"2021","unstructured":"de Waal, K. et al. A randomized placebo-controlled pilot trial of early targeted nonsteroidal anti-inflammatory drugs in preterm infants with a patent ductus arteriosus. J. Pediatr. 228, 82\u201386.e2, https:\/\/doi.org\/10.1016\/j.jpeds.2020.08.062 (2021).","journal-title":"J. Pediatr."},{"key":"3820_CR11","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1001\/jamapediatrics.2020.1447","volume":"174","author":"SI Sung","year":"2020","unstructured":"Sung, S. I. et al. Effect of nonintervention vs oral ibuprofen in patent ductus arteriosus in preterm infants: a randomized clinical trial. JAMA Pediatr. 174, 755\u2013763, https:\/\/doi.org\/10.1001\/jamapediatrics.2020.1447 (2020).","journal-title":"JAMA Pediatr."},{"key":"3820_CR12","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.ahj.2023.07.007","volume":"266","author":"HA Cheema","year":"2023","unstructured":"Cheema, H. A. et al. Expectant management of patent ductus arteriosus for preterm infants: a meta-analysis of randomized controlled trials. Am. Heart J. 266, 179\u2013183, https:\/\/doi.org\/10.1016\/j.ahj.2023.07.007 (2023).","journal-title":"Am. Heart J."},{"key":"3820_CR13","doi-asserted-by":"publisher","DOI":"10.1002\/wics.1523","volume":"13","author":"R Kelter","year":"2021","unstructured":"Kelter, R. Bayesian and frequentist testing for differences between two groups with parametric and nonparametric two\u2010sample tests. WIREs:Comput. Stat. 13, e1523, https:\/\/doi.org\/10.1002\/wics.1523 (2021).","journal-title":"WIREs:Comput. Stat."},{"key":"3820_CR14","doi-asserted-by":"publisher","unstructured":"Barto\u0161 F., Pawel S., Wagenmakers E.-J. When Evidence and Significance Collide. arXiv preprint arXiv:220604435. https:\/\/doi.org\/10.48550\/arXiv.2206.04435 (2022).","DOI":"10.48550\/arXiv.2206.04435"},{"key":"3820_CR15","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1164\/rccm.202006-2381CP","volume":"203","author":"FG Zampieri","year":"2021","unstructured":"Zampieri, F. G., Casey, J. D., Shankar-Hari, M., Harrel, F. E. & Harhay, M. O. Using Bayesian methods to augment the interpretation of critical care trials. An overview of theory and example reanalysis of the alveolar recruitment for acute respiratory distress syndrome trial. Am. J. Respir. Crit. Care Med 203, 543\u2013552, https:\/\/doi.org\/10.1164\/rccm.202006-2381CP (2021).","journal-title":"Am. J. Respir. Crit. Care Med"},{"key":"3820_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2024.113972","volume":"269","author":"AN Massaro","year":"2024","unstructured":"Massaro, A. N. et al. Measuring clinical benefit in neonatal randomized clinical trials: challenges and opportunities. J. Pediatr. 269, 113972, https:\/\/doi.org\/10.1016\/j.jpeds.2024.113972 (2024).","journal-title":"J. Pediatr."},{"key":"3820_CR17","doi-asserted-by":"publisher","first-page":"2208","DOI":"10.1001\/jama.2018.16916","volume":"320","author":"RJ Lewis","year":"2018","unstructured":"Lewis, R. J. & Angus, D. C. Time for clinicians to embrace their inner Bayesian?: reanalysis of results of a clinical trial of extracorporeal membrane oxygenation. JAMA 320, 2208\u20132210, https:\/\/doi.org\/10.1001\/jama.2018.16916 (2018).","journal-title":"JAMA"},{"key":"3820_CR18","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-019-0699-7","volume":"19","author":"D van Ravenzwaaij","year":"2019","unstructured":"van Ravenzwaaij, D., Monden, R. & Tendeiro, J. N. Loannidis JPA. Bayes factors for superiority, non-inferiority, and equivalence designs. BMC Med. Res. Methodol. 19, 71, https:\/\/doi.org\/10.1186\/s12874-019-0699-7 (2019).","journal-title":"BMC Med. Res. Methodol."},{"key":"3820_CR19","doi-asserted-by":"publisher","first-page":"6743","DOI":"10.1002\/sim.9170","volume":"40","author":"F Barto\u0161","year":"2021","unstructured":"Barto\u0161, F. et al. Bayesian model\u2010averaged meta\u2010analysis in medicine. Stat. Med. 40, 6743\u20136761, https:\/\/doi.org\/10.1002\/sim.9170 (2021).","journal-title":"Stat. Med."},{"key":"3820_CR20","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1080\/00031305.1999.10474443","volume":"53","author":"M Lavine","year":"1999","unstructured":"Lavine, M. & Schervish, M. J. Bayes factors: What they are and what they are not. Am. Stat. 53, 119\u2013122, https:\/\/doi.org\/10.1080\/00031305.1999.10474443 (1999).","journal-title":"Am. Stat."},{"key":"3820_CR21","doi-asserted-by":"publisher","first-page":"e0195474","DOI":"10.1371\/journal.pone.0195474","volume":"13","author":"R Hoekstra","year":"2018","unstructured":"Hoekstra, R., Monden, R., van Ravenzwaaij, D. & Wagenmakers, E. J. Bayesian reanalysis of null results reported in medicine: Strong yet variable evidence for the absence of treatment effects. PLoS One 13, e0195474, https:\/\/doi.org\/10.1371\/journal.pone.0195474 (2018).","journal-title":"PLoS One"},{"key":"3820_CR22","doi-asserted-by":"publisher","unstructured":"Barto\u0161 F. et al. Empirical prior distributions for Bayesian meta-analyses of binary and time to event outcomes. arXiv preprint arXiv:230611468. https:\/\/doi.org\/10.48550\/arXiv.2306.11468 (2023).","DOI":"10.48550\/arXiv.2306.11468"},{"key":"3820_CR23","doi-asserted-by":"publisher","first-page":"l4898","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JA Sterne","year":"2019","unstructured":"Sterne, J. A. et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 366, l4898, https:\/\/doi.org\/10.1136\/bmj.l4898 (2019).","journal-title":"BMJ"},{"key":"3820_CR24","doi-asserted-by":"publisher","unstructured":"Barto\u0161 F., Maier M., Quintana D. S. & Wagenmakers E. J. Adjusting for Publication Bias in JASP and R: Selection Models, PET-PEESE, and Robust Bayesian Meta-Analysis. AMPPS.5 https:\/\/doi.org\/10.1177\/25152459221109259 (2022).","DOI":"10.1177\/25152459221109259"},{"key":"3820_CR25","unstructured":"Lee M. & Wagenmakers E. J. Bayesian data analysis for cognitive science: A practical course. In: New York, NY: Cambridge University Press; (2013)."},{"key":"3820_CR26","doi-asserted-by":"crossref","unstructured":"Spiegelhalter D. J., Abrams K. R., Myles J. P. Bayesian approaches to clinical trials and health-care evaluation. Vol 13: John Wiley & Sons; (2004).","DOI":"10.1002\/0470092602"},{"key":"3820_CR27","doi-asserted-by":"publisher","first-page":"e600","DOI":"10.1002\/sta4.600","volume":"12","author":"F Barto\u0161","year":"2023","unstructured":"Barto\u0161, F. & Wagenmakers, E. J. A general approximation to nested Bayes factors with informed priors. Stat 12, e600, https:\/\/doi.org\/10.1002\/sta4.600 (2023).","journal-title":"Stat"},{"key":"3820_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.semperi.2023.151718","volume":"47","author":"RI Clyman","year":"2023","unstructured":"Clyman, R. I. & Hills, N. K. Patent ductus arteriosus (PDA) and pulmonary morbidity: can early targeted pharmacologic PDA treatment decrease the risk of bronchopulmonary dysplasia? Semin. Perinatol. 47, 151718, https:\/\/doi.org\/10.1016\/j.semperi.2023.151718 (2023).","journal-title":"Semin. Perinatol."},{"key":"3820_CR29","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1038\/s41372-021-01002-z","volume":"41","author":"N Bussmann","year":"2021","unstructured":"Bussmann, N. et al. Patent ductus arteriosus shunt elimination results in a reduction in adverse outcomes: a post hoc analysis of the PDA RCT cohort. J. Perinatol. 41, 1134\u20131141, https:\/\/doi.org\/10.1038\/s41372-021-01002-z (2021).","journal-title":"J. Perinatol."},{"key":"3820_CR30","doi-asserted-by":"publisher","first-page":"F45","DOI":"10.1136\/adc.2009.168682","volume":"96","author":"L Jones","year":"2011","unstructured":"Jones, L., Craven, P., Attia, J., Thakkinstian, A. & Wright, I. Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants. Arch. Dis. Child Fetal Neonatal Ed. 96, F45\u2013F52, https:\/\/doi.org\/10.1136\/adc.2009.168682 (2011).","journal-title":"Arch. Dis. Child Fetal Neonatal Ed."},{"key":"3820_CR31","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1001\/jama.2018.1896","volume":"319","author":"S Mitra","year":"2018","unstructured":"Mitra, S. et al. Association of placebo, indomethacin, ibuprofen, and acetaminophen with closure of hemodynamically significant patent ductus arteriosus in preterm infants: a systematic review and meta-analysis. JAMA 319, 1221\u20131238, https:\/\/doi.org\/10.1001\/jama.2018.1896 (2018).","journal-title":"JAMA"},{"key":"3820_CR32","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s12931-023-02342-4","volume":"24","author":"X Chen","year":"2023","unstructured":"Chen, X. et al. Vascular and pulmonary effects of ibuprofen on neonatal lung development. Respir. Res. 24, 39, https:\/\/doi.org\/10.1186\/s12931-023-02342-4 (2023).","journal-title":"Respir. Res."},{"key":"3820_CR33","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1038\/s41372-023-01697-2","volume":"43","author":"CJ Wright","year":"2023","unstructured":"Wright, C. J., McCulley, D. J., Mitra, S. & Jensen, E. A. Acetaminophen for the patent ductus arteriosus: has safety been adequately demonstrated? J. Perinatol. 43, 1230\u20131237, https:\/\/doi.org\/10.1038\/s41372-023-01697-2 (2023).","journal-title":"J. Perinatol."},{"key":"3820_CR34","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010061.pub5","volume":"12","author":"B Jasani","year":"2022","unstructured":"Jasani, B., Mitra, S. & Shah, P. S. Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants. Cochrane Database Syst. Rev. 12, CD010061, https:\/\/doi.org\/10.1002\/14651858.CD010061.pub5 (2022).","journal-title":"Cochrane Database Syst. Rev."},{"key":"3820_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113806","volume":"265","author":"K Singh","year":"2024","unstructured":"Singh, K., Concato, J. & Davis, J. M. Real-world evidence for neonatal drug development: challenges and opportunities. J. Pediatr. 265, 113806, https:\/\/doi.org\/10.1016\/j.jpeds.2023.113806 (2024).","journal-title":"J. Pediatr."},{"key":"3820_CR36","doi-asserted-by":"publisher","first-page":"687","DOI":"10.3390\/jpm12050687","volume":"12","author":"M Pierro","year":"2022","unstructured":"Pierro, M., Van Mechelen, K., van Westering-Kroon, E., Villamor-Martinez, E. & Villamor, E. Endotypes of prematurity and phenotypes of bronchopulmonary dysplasia: toward personalized neonatology. J. Pers. Med 12, 687, https:\/\/doi.org\/10.3390\/jpm12050687 (2022).","journal-title":"J. Pers. Med"},{"key":"3820_CR37","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/s41572-019-0127-7","volume":"5","author":"B Th\u00e9baud","year":"2019","unstructured":"Th\u00e9baud, B. et al. Bronchopulmonary dysplasia. Nat. Rev. Dis. Prim. 5, 78, https:\/\/doi.org\/10.1038\/s41572-019-0127-7 (2019).","journal-title":"Nat. Rev. Dis. Prim."},{"key":"3820_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.semperi.2022.151638","volume":"46","author":"EA Jensen","year":"2022","unstructured":"Jensen, E. A. et al. Contributions of the NICHD neonatal research network to the diagnosis, prevention, and treatment of bronchopulmonary dysplasia. Semin. Perinatol. 46, 151638, https:\/\/doi.org\/10.1016\/j.semperi.2022.151638 (2022).","journal-title":"Semin. Perinatol."},{"key":"3820_CR39","doi-asserted-by":"publisher","first-page":"e2345299","DOI":"10.1001\/jamanetworkopen.2023.45299","volume":"6","author":"E Villamor","year":"2023","unstructured":"Villamor, E. et al. Patent Ductus Arteriosus and Bronchopulmonary Dysplasia\u2013associated pulmonary hypertension: A Bayesian meta-analysis. JAMA Netw. Open 6, e2345299, https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.45299 (2023).","journal-title":"JAMA Netw. Open"},{"key":"3820_CR40","doi-asserted-by":"publisher","unstructured":"Villamor E. & Gonzalez-Luis G. E. Pulmonary hypertension and lung damage associated with prolonged exposure to patent Ductus Arteriosus in very preterm infants. Am. J. Respir. Crit. Care Med. https:\/\/doi.org\/10.1164\/rccm.202404-0694ED (2024).","DOI":"10.1164\/rccm.202404-0694ED"},{"key":"3820_CR41","doi-asserted-by":"publisher","unstructured":"Bjorkman K. R. et al. Patent Ductus Arteriosus and Lung MRI Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension. Am. J. Respir. Crit. Care Med. https:\/\/doi.org\/10.1164\/rccm.202404-0694ED (2024).","DOI":"10.1164\/rccm.202404-0694ED"},{"key":"3820_CR42","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1164\/rccm.202203-0570OC","volume":"207","author":"SJ Gentle","year":"2023","unstructured":"Gentle, S. J., Travers, C. P., Clark, M., Carlo, W. A. & Ambalavanan, N. Patent ductus arteriosus and development of bronchopulmonary dysplasia\u2013associated pulmonary hypertension. Am. J. Respir. Crit. Care Med. 207, 921\u2013928, https:\/\/doi.org\/10.1164\/rccm.202203-0570OC (2023).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"3820_CR43","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/s41390-023-02522-4","volume":"94","author":"H Nawaytou","year":"2023","unstructured":"Nawaytou, H., Hills, N. K. & Clyman, R. I. Patent ductus arteriosus and the risk of bronchopulmonary dysplasia-associated pulmonary hypertension. Pediatr. Res. 94, 547\u2013554, https:\/\/doi.org\/10.1038\/s41390-023-02522-4 (2023).","journal-title":"Pediatr. Res."},{"key":"3820_CR44","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1001\/jama.2017.15574","volume":"318","author":"M Quintana","year":"2017","unstructured":"Quintana, M., Viele, K. & Lewis, R. J. Bayesian analysis: using prior information to interpret the results of clinical trials. JAMA 318, 1605\u20131606, https:\/\/doi.org\/10.1001\/jama.2017.15574 (2017).","journal-title":"JAMA"},{"key":"3820_CR45","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jpeds.2022.10.010","volume":"254","author":"P Lemmers","year":"2023","unstructured":"Lemmers, P. et al. Delayed surgical closure of the patent Ductus Arteriosus: Does the brain pay the price? J. Pediatr. 254, 25\u201332, https:\/\/doi.org\/10.1016\/j.jpeds.2022.10.010 (2023).","journal-title":"J. Pediatr."},{"key":"3820_CR46","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3390\/jcdd11010026","volume":"11","author":"N Kikuchi","year":"2024","unstructured":"Kikuchi, N. et al. Correlation between the closure time of patent Ductus Arteriosus in preterm infants and long-term neurodevelopmental outcome. J. Cardiovasc Dev. Dis. 11, 26, https:\/\/doi.org\/10.3390\/jcdd11010026 (2024).","journal-title":"J. Cardiovasc Dev. Dis."},{"key":"3820_CR47","doi-asserted-by":"publisher","first-page":"370.e1","DOI":"10.1016\/j.ajog.2023.09.016","volume":"230","author":"GJ Sandoval","year":"2024","unstructured":"Sandoval, G. J. et al. Desirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial. Am. J. Obstet. Gynecol. 230, 370.e1\u2013e12 (2024).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"3820_CR48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113817","volume":"265","author":"M Gillam-Krakauer","year":"2024","unstructured":"Gillam-Krakauer, M. & Reese, J. We still don\u2019t know when to close a patent Ductus Arteriosus in infants born very premature. J. Pediatr. 265, 113817, https:\/\/doi.org\/10.1016\/j.jpeds.2023.113817 (2024).","journal-title":"J. Pediatr."},{"key":"3820_CR49","doi-asserted-by":"publisher","DOI":"10.1016\/j.semperi.2023.151720","volume":"47","author":"B Jasani","year":"2023","unstructured":"Jasani, B., Weisz, D. E., Reese, J. & Jain, A. Combination pharmacotherapy for patent ductus arteriosus: Rationale and evidence. Semin. Perinatol. 47, 151720, https:\/\/doi.org\/10.1016\/j.semperi.2023.151720 (2023).","journal-title":"Semin. Perinatol."}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-03820-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-03820-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-03820-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T12:12:12Z","timestamp":1758715932000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-03820-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,15]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["3820"],"URL":"https:\/\/doi.org\/10.1038\/s41390-025-03820-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.09.23.24314216","asserted-by":"object"}]},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,15]]},"assertion":[{"value":"24 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 January 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"EV is co-author of one of the trials included in the meta-analysis. The other authors have no conflicts of interest to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"As this systematic review and meta-analysis did not involve animal subjects or personally identifiable information on human subjects, ethics review board approval and patient consent were not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics"}}]}}