{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:55:37Z","timestamp":1785772537777,"version":"3.56.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>With current practice in neonatal resuscitation, the laryngeal mask airway plays a greater role in the delivery room. The International Liaison Committee on Resuscitation recommends administering epinephrine through the airway until intravenous access is obtained when extensive resuscitation is needed.<\/jats:p>","DOI":"10.1038\/s41390-025-04645-2","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:32:14Z","timestamp":1764689534000},"page":"2112-2114","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laryngeal mask epinephrine: expanding the airway toolbox in neonatal resuscitation"],"prefix":"10.1038","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8727-3017","authenticated-orcid":false,"given":"Praveen","family":"Chandrasekharan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Wilding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mausma","family":"Bawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,2]]},"reference":[{"key":"4645_CR1","doi-asserted-by":"publisher","first-page":"110536","DOI":"10.1016\/j.resuscitation.2025.110536","volume":"208","author":"F Eckart","year":"2025","unstructured":"Eckart, F., Kaufmann, M., Mense, L. & R\u00fcdiger, M. Descriptive dataset analysis of a survey on currently applied interventions in neonatal resuscitation (SCIN). Resuscitation 208, 110536 (2025).","journal-title":"Resuscitation"},{"key":"4645_CR2","doi-asserted-by":"publisher","first-page":"S524","DOI":"10.1161\/CIR.0000000000000902","volume":"142","author":"K Aziz","year":"2020","unstructured":"Aziz, K. et al. Part 5: Neonatal resuscitation: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 142, S524\u2013S550 (2020).","journal-title":"Circulation"},{"key":"4645_CR3","doi-asserted-by":"crossref","unstructured":"Weiner, G. M. & Zaichkin, J. Textbook of Neonatal Resuscitation (NRP) 8th edn (American Academy of Pediatrics, 2021).","DOI":"10.1542\/9781610025256"},{"key":"4645_CR4","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1542\/peds.2006-0416","volume":"118","author":"CA Barber","year":"2006","unstructured":"Barber, C. A. & Wyckoff, M. H. Use and efficacy of endotracheal versus intravenous epinephrine during neonatal cardiopulmonary resuscitation in the delivery room. Pediatrics 118, 1028\u20131034 (2006).","journal-title":"Pediatrics"},{"key":"4645_CR5","doi-asserted-by":"publisher","first-page":"2138","DOI":"10.1056\/NEJMoa2005333","volume":"383","author":"NJ Pejovic","year":"2020","unstructured":"Pejovic, N. J. et al. A randomized trial of laryngeal mask airway in neonatal resuscitation. N. Engl. J. Med. 383, 2138\u20132147 (2020).","journal-title":"N. Engl. J. Med."},{"key":"4645_CR6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3389\/fped.2020.00276","volume":"8","author":"M O\u2019Reilly","year":"2020","unstructured":"O\u2019Reilly, M. et al. Surfactant administration via laryngeal mask airway in neonates: a review of techniques and outcomes. Front. Pediatr. 8, 276 (2020).","journal-title":"Front. Pediatr."},{"key":"4645_CR7","doi-asserted-by":"publisher","first-page":"e353","DOI":"10.1542\/peds.2012-1795","volume":"131","author":"G Msemo","year":"2013","unstructured":"Msemo, G. et al. Newborn mortality and fresh stillbirth rates in Tanzania after Helping Babies Breathe training. Pediatrics 131, e353\u2013e360 (2013).","journal-title":"Pediatrics"},{"key":"4645_CR8","doi-asserted-by":"publisher","unstructured":"Abbasi, H. et al. Efficacy of laryngeal mask epinephrine in neonatal resuscitation: an ovine study. Pediatr. Res. 1\u20137 https:\/\/doi.org\/10.1038\/s41390-025-04070-5 (2025).","DOI":"10.1038\/s41390-025-04070-5"},{"key":"4645_CR9","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/S0140-6736(14)60496-7","volume":"384","author":"JE Lawn","year":"2014","unstructured":"Lawn, J. E. et al. Every Newborn: progress, priorities, and potential beyond survival. Lancet 384, 189\u2013205 (2014).","journal-title":"Lancet"},{"key":"4645_CR10","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1136\/emj.2007.057547","volume":"25","author":"KT Chen","year":"2008","unstructured":"Chen, K. T., Lin, H. J., Jeng, H. W., Lin, C. C. & Guo, H. R. The pharmacological effect of epinephrine administration via laryngeal mask airway in a porcine model of asphyxial cardiac arrest. Emerg. Med. J. 25, 722\u2013724 (2008).","journal-title":"Emerg. Med. J."}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-04645-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-04645-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-04645-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:20:24Z","timestamp":1785770424000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41390-025-04645-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,2]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["4645"],"URL":"https:\/\/doi.org\/10.1038\/s41390-025-04645-2","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,2]]},"assertion":[{"value":"21 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 November 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The lead author (P.C.) is a co-investigator on the original study discussed in this commentary. This relationship is disclosed here in the interest of full transparency. The commentary aims to provide a balanced and critical analysis of the findings and their implications for the broader field of neonatal resuscitation. External co-authors contributed to this revised version to maintain editorial integrity and independent analysis.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}