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We aimed to assess the prevalence and severity of post-traumatic stress symptoms (PTSS), depression, and anxiety among CCS and their parents, examine associations between these measures, and identify potential risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional study comprising 118 CCS aged 7\u201321 years and their parents, at least one year post-treatment. PTSS, depression and anxiety were assessed using validated questionnaires. Medical and sociodemographic data were collected from the medical charts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>PTSD criteria were met by 8.7% of CCS and 18.3% of parents, about a third reporting post-traumatic stress symptoms. Moderate-to-severe depression occurred in 22% of CCS and 7.6% of parents, and anxiety in 12.7% of CCS and 22% of parents. There were robust positive correlations between depression, anxiety, and PTSS within both CCS and parental self-reports. Parents\u2019 proxy- reports correlated more strongly with their self-report than with CCS self-reports. Predictors of PTSS included time since diagnosis, parent\u2019s education, parent\u2019s sex, type of cancer, and depression and anxiety level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study highlights the importance of screening both children and parents, prioritizing child self-report, and providing tailored, ongoing psychosocial support for CCS and their families.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Our study revealed high rates of psychological symptoms among CCS and their parents during the survivorship phase.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The dual-informant design using pediatric self-report, parent self-report, and parent-proxy report enabled exploration of interconnections between psychological symptoms of CCS and their parents.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Parents\u2019 perceptions of children\u2019s distress correlated more with their own emotional state than with children\u2019s self-reports, suggesting parental projection.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Predictors of post-traumatic stress symptoms, including time since diagnosis, parental education and biological-sex, depression and anxiety.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Our results emphasize the need for screening both children and parents, prioritizing child self-report, and providing tailored, ongoing psychosocial support for CCS and their families.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1038\/s41390-025-04724-4","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T12:09:19Z","timestamp":1766750959000},"page":"792-799","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Post-Traumatic Stress, depression and anxiety symptoms among childhood cancer survivors and their parents"],"prefix":"10.1038","volume":"100","author":[{"given":"Maya","family":"Yardeni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilanit","family":"Hasson-Ohayon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reut","family":"Pienik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Mashiach-Eizenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Ben Ami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eve","family":"Stern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Golan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalia","family":"Waldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amos","family":"Toren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalit","family":"Modan-Moses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"4724_CR1","first-page":"591","volume":"21","author":"F Edition","year":"2013","unstructured":"Edition, F. 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