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The study was conducted in accordance with the relevant guidelines and regulations for the care and use of laboratory animals. Furthermore, we confirm that this manuscript adheres to the ARRIVE guidelines for reporting animal research.","order":2,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"This study did not involve human experiments.","order":3,"name":"Ethics","label":"Consent statement","group":{"name":"EthicsHeading","label":"Ethics"}}]}}