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HRQoL was rated with the Spinal Cord Injury Quality of Life Questionnaire (SCI QL-23). Associations were investigated using multivariable linear regression analyses.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The median rating of global QoL (scale range 0\u2013100) was relatively high at both assessments (67 and 83, respectively). There was a large variability in all HRQoL-domains and no significant changes over 6 years. As compared to an AIS D injury, a tetraplegia AIS A\u2013C injury and tetraplegia and paraplegia AIS A\u2013C injuries were associated with positive change in depressive symptoms and global QoL, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Older adults aging with long-term SCI show large variations in all HRQoL-domains and have the potential to maintain a high and stable level of HRQoL over time. Persons with AIS D injuries may need increased attention to mitigate negative changes in depressive symptoms and global QoL. Further studies are needed to identify modifiable factors associated with changes in HRQoL in older adults aging with long-term SCI.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1038\/s41393-020-00579-0","type":"journal-article","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T12:02:51Z","timestamp":1605182571000},"page":"769-776","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Changes in health-related quality of life among older adults aging with long-term spinal cord injury"],"prefix":"10.1038","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1454-1655","authenticated-orcid":false,"given":"Sophie","family":"J\u00f6rgensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Valentina","family":"Costa Andersson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Lexell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,11,12]]},"reference":[{"key":"579_CR1","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1053\/apmr.2002.36954","volume":"83","author":"DS Tulsky","year":"2002","unstructured":"Tulsky DS, Rosenthal M. 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All participants received oral and written information about the study procedures, provided written informed consent to participate and were informed about their right to withdraw at any time without giving a reason. We certify that all applicable institutional and governmental regulations concerning the ethical use of human volunteers were followed during the course of this research.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}