{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:24:27Z","timestamp":1791246267466,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Spinal Cord"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1038\/s41393-026-01210-4","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:03:47Z","timestamp":1777464227000},"page":"563-570","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Development and validation of an MRI-Based nomogram for predicting neurological recovery after acute cervical spinal cord injury"],"prefix":"10.1038","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1575-9898","authenticated-orcid":false,"given":"Marofe","family":"Hossain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9496-1167","authenticated-orcid":false,"given":"Sun","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0937-4017","authenticated-orcid":false,"given":"Ahamed","family":"Yeasin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9162-5032","authenticated-orcid":false,"given":"Yongxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"1210_CR1","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/sc.2012.158","volume":"52","author":"BB Lee","year":"2014","unstructured":"Lee BB, Cripps RA, Fitzharris M, Wing PC. The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate. Spinal Cord. 2014;52:110\u20136.","journal-title":"Spinal Cord"},{"key":"1210_CR2","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1038\/s41393-019-0295-z","volume":"57","author":"J Martineau","year":"2019","unstructured":"Martineau J, Goulet J, Richard-Denis A, Mac-Thiong JM. The relevance of MRI for predicting neurological recovery following cervical traumatic spinal cord injury. Spinal Cord. 2019;57:866\u201373.","journal-title":"Spinal Cord"},{"key":"1210_CR3","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1093\/neuros\/nyw080","volume":"80","author":"CS Ahuja","year":"2017","unstructured":"Ahuja CS, Nori S, Tetreault L, Wilson J, Kwon B, Harrop J, et al. Traumatic spinal cord injury-repair and regeneration. Neurosurgery. 2017;80:S9\u2013s22.","journal-title":"Neurosurgery"},{"key":"1210_CR4","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/s41393-021-00648-y","volume":"60","author":"S Kirshblum","year":"2022","unstructured":"Kirshblum S, Schmidt Read M, Rupp R. Classification challenges of the 2019 revised international standards for neurological classification of spinal cord injury (ISNCSCI). Spinal Cord. 2022;60:11\u20137.","journal-title":"Spinal Cord"},{"key":"1210_CR5","doi-asserted-by":"publisher","first-page":"536","DOI":"10.4184\/asj.2016.10.3.536","volume":"10","author":"T Takao","year":"2016","unstructured":"Takao T, Okada S, Morishita Y, Maeda T, Kubota K, Ideta R, et al. Clinical influence of cervical spinal canal stenosis on neurological outcome after traumatic cervical spinal cord injury without major fracture or dislocation. Asian Spine J. 2016;10:536\u201342.","journal-title":"Asian Spine J"},{"key":"1210_CR6","doi-asserted-by":"publisher","first-page":"2324","DOI":"10.1007\/s00586-017-5097-4","volume":"26","author":"J Rutges","year":"2017","unstructured":"Rutges J, Kwon BK, Heran M, Ailon T, Street JT, Dvorak MF. A prospective serial MRI study following acute traumatic cervical spinal cord injury. Eur Spine J. 2017;26:2324\u201332.","journal-title":"Eur Spine J"},{"key":"1210_CR7","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1097\/BSD.0000000000000287","volume":"28","author":"CD Witiw","year":"2015","unstructured":"Witiw CD, Fehlings MG. Acute spinal cord injury. J Spinal Disord Tech. 2015;28:202\u201310.","journal-title":"J Spinal Disord Tech"},{"key":"1210_CR8","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3171\/2009.5.SPINE08940","volume":"12","author":"M Yagi","year":"2010","unstructured":"Yagi M, Ninomiya K, Kihara M, Horiuchi Y. Long-term surgical outcome and risk factors in patients with cervical myelopathy and a change in signal intensity of intramedullary spinal cord on magnetic resonance imaging. J Neurosurg Spine. 2010;12:59\u201365.","journal-title":"J Neurosurg Spine"},{"key":"1210_CR9","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1097\/PHM.0000000000001701","volume":"100","author":"P Mputu Mputu","year":"2021","unstructured":"Mputu Mputu P, Beaus\u00e9jour M, Richard-Denis A, Mac-Thiong JM. Early predictors of neurological outcomes after traumatic spinal cord injury: a systematic review and proposal of a conceptual framework. Am J Phys Med Rehabil. 2021;100:700\u201311.","journal-title":"Am J Phys Med Rehabil"},{"key":"1210_CR10","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1089\/neu.2017.5321","volume":"38","author":"Y Facchinello","year":"2021","unstructured":"Facchinello Y, Beaus\u00e9jour M, Richard-Denis A, Thompson C, Mac-Thiong JM. Use of regression tree analysis for predicting the functional outcome after traumatic spinal cord injury. J Neurotrauma. 2021;38:1285\u201391.","journal-title":"J Neurotrauma"},{"key":"1210_CR11","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1016\/j.spinee.2018.08.016","volume":"19","author":"P Phan","year":"2019","unstructured":"Phan P, Budhram B, Zhang Q, Rivers CS, Noonan VK, Plashkes T, et al. Highlighting discrepancies in walking prediction accuracy for patients with traumatic spinal cord injury: an evaluation of validated prediction models using a Canadian Multicenter Spinal Cord Injury Registry. Spine J. 2019;19:703\u201310.","journal-title":"Spine J"},{"key":"1210_CR12","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1016\/j.spinee.2015.04.041","volume":"15","author":"K Stephan","year":"2015","unstructured":"Stephan K, Huber S, H\u00e4berle S, Kanz KG, B\u00fchren V, van Griensven M, et al. Spinal cord injury-incidence, prognosis, and outcome: an analysis of the TraumaRegister DGU. Spine J. 2015;15:1994\u20132001.","journal-title":"Spine J"},{"key":"1210_CR13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-25809-8","volume":"12","author":"KJP van Wessem","year":"2022","unstructured":"van Wessem KJP, Niemeyer MJS, Leenen LPH. Polytrauma patients with severe cervical spine injuries are different than with severe TBI despite similar AIS scores. Sci Rep. 2022;12:21538.","journal-title":"Sci Rep"},{"key":"1210_CR14","doi-asserted-by":"publisher","first-page":"490","DOI":"10.3171\/2015.1.SPINE141013","volume":"23","author":"CK Kepler","year":"2015","unstructured":"Kepler CK, Kong C, Schroeder GD, Hjelm N, Sayadipour A, Vaccaro AR, et al. Early outcome and predictors of early outcome in patients treated surgically for central cord syndrome. J Neurosurg Spine. 2015;23:490\u20134.","journal-title":"J Neurosurg Spine"},{"key":"1210_CR15","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.rehab.2011.02.003","volume":"54","author":"G Lamothe","year":"2011","unstructured":"Lamothe G, Muller F, Vital JM, Goossens D, Barat M. Evolution of spinal cord injuries due to cervical canal stenosis without radiographic evidence of trauma (SCIWORET): a prospective study. Ann Phys Rehabil Med. 2011;54:213\u201324.","journal-title":"Ann Phys Rehabil Med"},{"key":"1210_CR16","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S1474-4422(20)30406-3","volume":"20","author":"JH Badhiwala","year":"2021","unstructured":"Badhiwala JH, Wilson JR, Witiw CD, Harrop JS, Vaccaro AR, Aarabi B, et al. The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data. Lancet Neurol. 2021;20:117\u201326.","journal-title":"Lancet Neurol"},{"key":"1210_CR17","doi-asserted-by":"publisher","first-page":"3011","DOI":"10.1089\/neu.2021.0177","volume":"38","author":"M Balas","year":"2021","unstructured":"Balas M, Pr\u00f6mmel P, Nguyen L, Jack AS, Lebovic G, Badhiwala JH, et al. Reality of accomplishing surgery within 24\u2009h for complete cervical spinal cord injury: clinical practices and safety. J Neurotrauma. 2021;38:3011\u20139.","journal-title":"J Neurotrauma"},{"key":"1210_CR18","doi-asserted-by":"publisher","first-page":"2609","DOI":"10.1089\/neu.2018.6277","volume":"36","author":"PV Ter Wengel","year":"2019","unstructured":"Ter Wengel PV, Martin E, De Witt Hamer PC, Feller RE, van Oortmerssen JAE, van der Gaag NA, et al. Impact of early (<24\u2009h) surgical decompression on neurological recovery in thoracic spinal cord injury: a meta-analysis. J Neurotrauma. 2019;36:2609\u201317.","journal-title":"J Neurotrauma"},{"key":"1210_CR19","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1055\/s-0042-1757728","volume":"17","author":"A Yadav","year":"2022","unstructured":"Yadav A, Singh A, Verma R, Singh VK, Ojha BK, Chandra A, et al. Pediatric cervical spine injuries. Asian J Neurosurg. 2022;17:557\u201362.","journal-title":"Asian J Neurosurg"},{"key":"1210_CR20","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1093\/neuros\/nyw053","volume":"80","author":"B Aarabi","year":"2017","unstructured":"Aarabi B, Sansur CA, Ibrahimi DM, Simard JM, Hersh DS, Le E, et al. Intramedullary lesion length on postoperative magnetic resonance imaging is a strong predictor of ASIA impairment scale grade conversion following decompressive surgery in cervical spinal cord injury. Neurosurgery. 2017;80:610\u201320.","journal-title":"Neurosurgery"},{"key":"1210_CR21","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1089\/neu.2015.3963","volume":"32","author":"N Evaniew","year":"2015","unstructured":"Evaniew N, Noonan VK, Fallah N, Kwon BK, Rivers CS, Ahn H, et al. Methylprednisolone for the treatment of patients with acute spinal cord injuries: a propensity score-matched cohort study from a canadian multi-center spinal cord injury registry. J Neurotrauma. 2015;32:1674\u201383.","journal-title":"J Neurotrauma"},{"key":"1210_CR22","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1213\/ANE.0000000000001906","volume":"124","author":"JE Sunshine","year":"2017","unstructured":"Sunshine JE, Dagal A, Burns SP, Bransford RJ, Zhang F, Newman SF, et al. Methylprednisolone therapy in acute traumatic spinal cord injury: analysis of a regional spinal cord model systems database. Anesth Analg. 2017;124:1200\u20135.","journal-title":"Anesth Analg"},{"key":"1210_CR23","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1089\/neu.2016.4499","volume":"33","author":"N Evaniew","year":"2016","unstructured":"Evaniew N, Noonan VK, Fallah N, Rivers CS, Dvorak MF. Methylprednisolone for the treatment of patients with acute spinal cord injuries: response. J Neurotrauma. 2016;33:975\u20136.","journal-title":"J Neurotrauma"},{"key":"1210_CR24","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/S0140-6736(02)07603-1","volume":"359","author":"JW McDonald","year":"2002","unstructured":"McDonald JW, Sadowsky C. Spinal-cord injury. Lancet. 2002;359:417\u201325.","journal-title":"Lancet"},{"key":"1210_CR25","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1089\/neu.2013.3034","volume":"31","author":"SA Figley","year":"2014","unstructured":"Figley SA, Khosravi R, Legasto JM, Tseng YF, Fehlings MG. Characterization of vascular disruption and blood-spinal cord barrier permeability following traumatic spinal cord injury. J Neurotrauma. 2014;31:541\u201352.","journal-title":"J Neurotrauma"},{"key":"1210_CR26","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1038\/jcbfm.2012.113","volume":"32","author":"EA Winkler","year":"2012","unstructured":"Winkler EA, Sengillo JD, Bell RD, Wang J, Zlokovic BV. Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability. J Cereb Blood Flow Metab. 2012;32:1841\u201352.","journal-title":"J Cereb Blood Flow Metab"},{"key":"1210_CR27","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.spinee.2013.02.006","volume":"13","author":"N Aebli","year":"2013","unstructured":"Aebli N, R\u00fcegg TB, Wicki AG, Petrou N, Krebs J. Predicting the risk and severity of acute spinal cord injury after a minor trauma to the cervical spine. Spine J. 2013;13:597\u2013604.","journal-title":"Spine J"},{"key":"1210_CR28","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3171\/2014.10.SPINE14346","volume":"22","author":"TB R\u00fcegg","year":"2015","unstructured":"R\u00fcegg TB, Wicki AG, Aebli N, Wisianowsky C, Krebs J. The diagnostic value of magnetic resonance imaging measurements for assessing cervical spinal canal stenosis. J Neurosurg Spine. 2015;22:230\u20136.","journal-title":"J Neurosurg Spine"}],"container-title":["Spinal Cord"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41393-026-01210-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41393-026-01210-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41393-026-01210-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T01:03:46Z","timestamp":1781053426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41393-026-01210-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,29]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["1210"],"URL":"https:\/\/doi.org\/10.1038\/s41393-026-01210-4","relation":{},"ISSN":["1362-4393","1476-5624"],"issn-type":[{"value":"1362-4393","type":"print"},{"value":"1476-5624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,29]]},"assertion":[{"value":"5 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 April 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This study was conducted in accordance with the ethical principles of the Declaration of Helsinki and its later amendments. Ethical approval was obtained from the Ethics Committee of Yangzhou University School of Clinical Medicine (Approval No: 2024ky22) prior to the commencement of the study. As this study involved human participants only, no animal (live vertebrate) experiments were performed, and therefore no additional animal ethics committee approval was required. All methods were performed in accordance with the relevant guidelines and regulations. Due to the retrospective nature of this study, the requirement for informed consent was waived by the Ethics Committee. All patient data were anonymized to ensure confidentiality and privacy.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}