{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T16:09:15Z","timestamp":1785600555902,"version":"3.56.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Spinal Cord Ser Cases"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Tenosynovial giant cell tumours (TSGCTs) usually arise from the synovial membranes of tendon sheaths, bursa, and joints. They are rarely found in the spine. Lesions of the upper cervical spine (C1\/2) are extremely rare, with only 13 previous cases reported in the literature. Of these, all previous anterior upper cervical cases (C1\/2) have been deemed unresectable and have been managed with immunotherapy or radiological surveillance.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We report two cases of TSGCST in the cervical spine: one with a lesion at C1\/2 and another at C6\/7.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Discussion<\/jats:title>\n                <jats:p>The location of our C1\/2 lesion was unique, allowing for a new endoscopic endonasal tissue biopsy method and a new transoral surgical approach for successful gross total resection. Our C6\/7 lesion had a more typical location and was removed via a C6\/7 laminectomy.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1038\/s41394-022-00538-2","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T04:02:28Z","timestamp":1659499348000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tenosynovial giant cell tumours of the upper and lower cervical spine: two case reports"],"prefix":"10.1038","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9740-2564","authenticated-orcid":false,"given":"Ning","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananthababu Pattavilakom","family":"Sadasivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,3]]},"reference":[{"key":"538_CR1","doi-asserted-by":"publisher","first-page":"3394","DOI":"10.12998\/wjcc.v9.i14.3394","volume":"9","author":"JH Zhu","year":"2021","unstructured":"Zhu JH, Li M, Liang Y, Wu JH. Tenosynovial giant cell tumor involving the cervical spine: a case report. World J Clin Cases. 2021;9:3394\u2013402.","journal-title":"World J Clin Cases"},{"key":"538_CR2","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/s00256-020-03569-8","volume":"50","author":"YJ Kim","year":"2021","unstructured":"Kim YJ, Hong JH, Park JH, Cho SJ. Tenosynovial giant cell tumor of the upper cervical spine arising from the posterior atlanto-occipital membrane: a case report. Skelet Radio. 2021;50:451\u20135.","journal-title":"Skelet Radio"},{"key":"538_CR3","first-page":"804","volume":"24","author":"K Wang","year":"2014","unstructured":"Wang K, Zhu B, Yang S, Liu Z, Yu M, Liu X, et al. Primary diffuse-type tenosynovial giant cell tumor of the spine: a report of 3 cases and systemic review of the literature. 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