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Because differential diagnosis is difficult, the frequency is poorly known. The burden is huge for people suffering from this disorder but a management associating psychological and pharmacological approach could be very helpful. Classification, psychopathology, and physiopathology are still debating. New data from brain imaging could be very helpful. Psychological factors are known to modulate itch in all patients, but there is a specific diagnosis of psychogenic itch that must be proposed cautiously. Neurophysiological and psychological theories are not mutually exclusive and can be used to better understand this disorder. Itch can be mentally induced. Opioids and other neurotransmitters, such as acetylcholine and dopamine, are probably involved in this phenomenon.<\/jats:p>","DOI":"10.1038\/s41398-018-0097-7","type":"journal-article","created":{"date-parts":[[2018,2,28]],"date-time":"2018-02-28T13:20:27Z","timestamp":1519824027000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Psychogenic itch"],"prefix":"10.1038","volume":"8","author":[{"given":"Laurent","family":"Misery","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Dutray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Chastaing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Schollhammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie G.","family":"Consoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silla M.","family":"Consoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,3,1]]},"reference":[{"key":"97_CR1","first-page":"607","volume":"16","author":"W Harth","year":"2006","unstructured":"Harth, W., Hermes, B., Niemeier, V. & Gieler, U. 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S.M.C.\u2014conferences or brochures: Sanofi, Gilead, Bouchara-Recordati, Merck-Sharpe & Dohme, and NovoNordisk; scientific board of a clinical trial: Gilead; travel funds: Sanofi. S.D., M.C., M.S., and S.G.C. declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"52"}}