{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:46:26Z","timestamp":1790444786840,"version":"4.1.0"},"reference-count":114,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:00:00Z","timestamp":1534377600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:00:00Z","timestamp":1534377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000025","name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01 MH042984"],"award-info":[{"award-number":["R01 MH042984"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"U.S. Department of Health & Human Services | NIH | National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01 MH092793"],"award-info":[{"award-number":["R01 MH092793"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005197","name":"Hilda and Preston Davis Foundation","doi-asserted-by":"publisher","award":["xxxxxx"],"award-info":[{"award-number":["xxxxxx"]}],"id":[{"id":"10.13039\/100005197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH113588"],"award-info":[{"award-number":["R01 MH113588"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH113588"],"award-info":[{"award-number":["R01 MH113588"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["F32 MH108311"],"award-info":[{"award-number":["F32 MH108311"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH092793"],"award-info":[{"award-number":["R01 MH092793"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Transl Psychiatry"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Interoception, or the sensing and integration of bodily state signals, has been implicated in anorexia nervosa (AN), given that the hallmark symptoms involve food restriction and body image disturbance. Here we focus on brain response to the anticipation and experience of affective interoceptive stimuli. Women remitted from AN (RAN;<jats:italic>N<\/jats:italic>\u2009=\u200918) and healthy comparison women (CW;<jats:italic>N<\/jats:italic>\u2009=\u200926) underwent a pleasant affective touch paradigm consisting of gentle strokes with a soft brush administered to the forearm or palm during functional neuroimaging. RAN had a lower brain response relative to CW during anticipation of touch, but a greater response when experiencing touch in the right ventral mid-insula. In RAN, this reduced anticipatory response was associated with higher levels of harm avoidance. Exploratory analyses in RAN also suggested that lower response during touch anticipation was associated with greater body dissatisfaction and higher perceived touch intensity ratings. This reduced responsivity to the anticipation of pleasant affective interoceptive stimuli in association with higher harm avoidance, along with an elevated response to the experience of touch, suggests an impaired ability in AN to predict and interpret incoming physiological stimuli. Impaired interoception may thus impact one\u2019s sense of self, thereby supporting observations of disturbed body image and avoidance of affective and social stimuli. Therapeutic approaches that help AN to better anticipate and interpret salient affective stimuli or improve tolerance of interoceptive experiences may be an important addition to current interventions.<\/jats:p>","DOI":"10.1038\/s41398-018-0218-3","type":"journal-article","created":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T14:20:58Z","timestamp":1534429258000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Neural hypersensitivity to pleasant touch in women remitted from anorexia nervosa"],"prefix":"10.1038","volume":"8","author":[{"given":"Amanda","family":"Bischoff-Grethe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina E.","family":"Wierenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura A.","family":"Berner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan N.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Bailer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin P.","family":"Paulus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter H.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,8,16]]},"reference":[{"key":"218_CR1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders DSM-V (5th ed). Washington, DC 2013.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"218_CR2","first-page":"132","volume":"214","author":"T Oberndorfer","year":"2013","unstructured":"Oberndorfer, T. et al. Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am. J. Psychiatry 214, 132\u2013141 (2013).","journal-title":"Am. J. Psychiatry"},{"key":"218_CR3","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/sj.npp.1301443","volume":"33","author":"A Wagner","year":"2008","unstructured":"Wagner, A. et al. Altered insula response to a taste stimulus in individuals recovered from restricting-type anorexia nervosa. Neuropsychopharmacology 33, 513\u2013523 (2008).","journal-title":"Neuropsychopharmacology"},{"key":"218_CR4","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1503\/jpn.150103","volume":"41","author":"G Frank","year":"2016","unstructured":"Frank, G., Collier, S., Shott, M. & O\u2019Reilly, R. Prediction error and somatosensory insula activation in women recovered from anorexia nervosa. J. Psychiatry Neurosci. 41, 304\u2013311 (2016).","journal-title":"J. Psychiatry Neurosci."},{"key":"218_CR5","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.biopsych.2011.05.028","volume":"70","author":"F Cowdrey","year":"2011","unstructured":"Cowdrey, F., Park, R., Harmer, C. & McCabe, C. Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa. Biol. Psych. 70, 736\u2013743 (2011).","journal-title":"Biol. Psych."},{"key":"218_CR6","first-page":"213","volume":"38","author":"P Monteleone","year":"2013","unstructured":"Monteleone, P. & Maj, M. Dysfunctions of leptin, ghrelin, BDNF and endocannabinoids in eating disorders: beyond the homeostatic control of food intake. Psychoneuroendocrinology 38, 213\u2013333 (2013).","journal-title":"Psychoneuroendocrinology"},{"key":"218_CR7","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/j.jpeds.2013.03.011","volume":"163","author":"M Perez","year":"2013","unstructured":"Perez, M., Coley, B., Crandall, W., Di Lorenzo, C. & Bravender, T. Effect of nutritional rehabilitation on gastric motility and somatization in adolescents with anorexia. J. Pediatr. 163, 867\u201372 e1 (2013).","journal-title":"J. Pediatr."},{"key":"218_CR8","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/npp.2015.174","volume":"41","author":"K Kerr","year":"2016","unstructured":"Kerr, K. et al. Altered insula activity during visceral interoception in weight-restored patients with anorexia nervosa. Neuropsychopharmacology 41, 521\u2013528 (2016).","journal-title":"Neuropsychopharmacology"},{"key":"218_CR9","first-page":"1","volume":"17","author":"L Berner","year":"2017","unstructured":"Berner, L. et al. Altered interoceptive activation before, during, and after aversive breathing load in women remitted from anorexia nervosa. Psychol. Med. 17, 1\u201313 (2017).","journal-title":"Psychol. Med."},{"key":"218_CR10","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1002\/eat.22045","volume":"46","author":"I Strigo","year":"2013","unstructured":"Strigo, I. et al. Altered insula activation during pain anticipation in individuals recovered from anorexia nervosa: evidence of interoceptive dysregulation. Int. J. Eat. Disord 46, 23\u201333 (2013).","journal-title":"Int. J. Eat. Disord"},{"key":"218_CR11","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1038\/nrn894","volume":"3","author":"AD Craig","year":"2002","unstructured":"Craig, A. D. How do you feel? Interoception: the sense of the physiological condition of the body. Nat. Rev. Neurosci. 3, 655\u2013666 (2002).","journal-title":"Nat. Rev. Neurosci."},{"key":"218_CR12","doi-asserted-by":"publisher","first-page":"1494","DOI":"10.1038\/nn.2411","volume":"12","author":"S Khalsa","year":"2009","unstructured":"Khalsa, S., Rudrauf, D., Feinstein, J. & Tranel, D. The pathways of interoceptive awareness. Nat. Neurosci. 12, 1494\u20131496 (2009).","journal-title":"Nat. Neurosci."},{"key":"218_CR13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110087","volume":"9","author":"S Gaudio","year":"2014","unstructured":"Gaudio, S., Brooks, S. & Riva, G. Nonvisual multisensory impairment of body perception in anorexia nervosa: a systematic review of neuropsychological studies. PLoS Genet. 9, e110087 (2014).","journal-title":"PLoS Genet."},{"key":"218_CR14","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1207\/s15327752jpa5002_15","volume":"50","author":"TF Cash","year":"1986","unstructured":"Cash, T. F. & Green, G. K. Body weight and body image among college women: perception, cognition, and affect. J. Pers. Assess. 50, 290\u2013301 (1986).","journal-title":"J. Pers. Assess."},{"key":"218_CR15","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.cognition.2013.11.020","volume":"131","author":"H van Stralen","year":"2014","unstructured":"van Stralen, H. et al. Affective touch modulates the rubber hand illusion. Cognition 131, 147\u2013158 (2014).","journal-title":"Cognition"},{"key":"218_CR16","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3389\/fpsyg.2013.00703","volume":"4","author":"L Crucianelli","year":"2013","unstructured":"Crucianelli, L., Metcalf, N., Fotopoulou, A. & Jenkinson, P. Bodily pleasure matters: velocity of touch modulates body ownership during the rubber hand illusion. Front. Psychol. 4, 703 (2013).","journal-title":"Front. Psychol."},{"key":"218_CR17","first-page":"100","volume":"10","author":"G D\u2019Alessandro","year":"2016","unstructured":"D\u2019Alessandro, G., Cerritelli, F. & Cortelli, P. Sensitization and interoception as key neurological concepts in osteopathy and other manual medicines. Front. Neurosci. 10, 100 (2016).","journal-title":"Front. Neurosci."},{"key":"218_CR18","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/j.neuron.2014.05.001","volume":"82","author":"F McGlone","year":"2014","unstructured":"McGlone, F., Wessberg, J. & Olausson, H. Discriminative and affective touch: sensing and feeling. Neuron 82, 737\u2013755 (2014).","journal-title":"Neuron"},{"key":"218_CR19","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.neubiorev.2017.03.017","volume":"77","author":"D Badoud","year":"2017","unstructured":"Badoud, D. & Tsakiris, M. From the body\u2019s viscera to the body\u2019s image: Is there a link between interoception and body image concerns? Neurosci. Biobehav. Rev. 77, 237\u2013246 (2017).","journal-title":"Neurosci. Biobehav. Rev."},{"key":"218_CR20","doi-asserted-by":"publisher","first-page":"2909","DOI":"10.1016\/j.neuropsychologia.2013.08.014","volume":"51","author":"K Suzuki","year":"2013","unstructured":"Suzuki, K., Garfinkel, S. N., Critchley, H. D. & Seth, A. Multisensory integration across exteroceptive and interoceptive domains modulates self-experience in the rubber-hand illusion. Neuropsychologia 51, 2909\u20132917 (2013).","journal-title":"Neuropsychologia"},{"key":"218_CR21","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1080\/17470218.2016.1181768","volume":"70","author":"M Tsakiris","year":"2017","unstructured":"Tsakiris, M. The multisensory basis of the self: From body to identity to others [Formula: see text]. Q. J. Exp. Psychol. (Hove). 70, 597\u2013609 (2017).","journal-title":"Q. J. Exp. Psychol. (Hove)."},{"key":"218_CR22","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1146\/annurev.psych.56.091103.070229","volume":"57","author":"W Schulz","year":"2006","unstructured":"Schulz, W. Behavioral theories and the neurophysiology of reward. Ann. Rev. Psychol. 57, 87\u2013115 (2006).","journal-title":"Ann. Rev. Psychol."},{"key":"218_CR23","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.biopsych.2006.04.038","volume":"60","author":"A Simmons","year":"2006","unstructured":"Simmons, A., Strigo, I., Matthews, S., Paulus, M. & Stein, M. Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects. Biol. Psychiatry 60, 402\u2013409 (2006).","journal-title":"Biol. Psychiatry"},{"key":"218_CR24","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.biopsych.2006.03.042","volume":"60","author":"M Paulus","year":"2006","unstructured":"Paulus, M. & Stein, M. B. An insular view of anxiety. Biol. Psychiatry 60, 383\u2013387 (2006).","journal-title":"Biol. Psychiatry"},{"key":"218_CR25","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1097\/00006842-196203000-00009","volume":"24","author":"H Bruch","year":"1962","unstructured":"Bruch, H. Perceptual and conceptual disturbances in anorexia nervosa. Psychosom. Med. 24, 187\u2013194 (1962).","journal-title":"Psychosom. Med."},{"key":"218_CR26","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1159\/000079420","volume":"37","author":"S Fassino","year":"2004","unstructured":"Fassino, S., Piero, A., Gramaglia, C. & Abbate-Daga, G. Clinical, psychopathological and personality correlates of interoceptive awareness in anorexia nervosa, bulimia nervosa and obesity. Psychopathology 37, 168\u2013174 (2004).","journal-title":"Psychopathology"},{"key":"218_CR27","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1002\/eat.22460","volume":"49","author":"A Brand-Gothelf","year":"2016","unstructured":"Brand-Gothelf, A. et al. Sensory modulation disorder symptoms in anorexia nervosa and bulimia nervosa: a pilot study. Int. J. Eat. Disord. 49, 59\u201368 (2016).","journal-title":"Int. J. Eat. Disord."},{"key":"218_CR28","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.brat.2013.01.010","volume":"51","author":"N Zucker","year":"2013","unstructured":"Zucker, N. et al. Subjective experience of sensation in anorexia nervosa. Behav. Res. Ther. 51, 256\u2013265 (2013).","journal-title":"Behav. Res. Ther."},{"key":"218_CR29","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1097\/01.chi.0000227876.19909.48","volume":"45","author":"K Bar","year":"2006","unstructured":"Bar, K. et al. Changes of pain perception, autonomic function, and endocrine parameters during treatment of anorectic adolescents. J. Am. Acad. Child Adolsc. Psychiatry 45, 1068\u20131076 (2006).","journal-title":"J. Am. Acad. Child Adolsc. Psychiatry"},{"key":"218_CR30","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0022-3999(96)00088-8","volume":"41","author":"M de Zwaan","year":"1996","unstructured":"de Zwaan, M., Biener, D., Bach, M., Wiesnagrotzki, S. & Stacher, G. Pain sensitivity, alexithymia, and depression in patients with eating disorders: are they related? J. Psychosom. Res. 41, 65\u201370 (1996).","journal-title":"J. Psychosom. Res."},{"key":"218_CR31","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1016\/S0006-3223(98)00177-2","volume":"45","author":"N Raymond","year":"1999","unstructured":"Raymond, N. et al. Elevated pain threshold in anorexia nervosa subjects. Biol. Psychiatry 45, 1389\u20131392 (1999).","journal-title":"Biol. Psychiatry"},{"key":"218_CR32","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.eatbeh.2008.02.001","volume":"9","author":"O Pollatos","year":"2008","unstructured":"Pollatos, O. et al. Reduced perception of bodily signals in anorexia nervosa. Eat. Behav. 9, 381\u2013388 (2008).","journal-title":"Eat. Behav."},{"key":"218_CR33","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1002\/eat.22387","volume":"48","author":"S Khalsa","year":"2015","unstructured":"Khalsa, S. et al. Altered interoceptive awareness in anorexia nervosa: Effects of meal anticipation, consumption and bodily arousal. Int. J. Eat. Disord. 48, 889\u2013897 (2015).","journal-title":"Int. J. Eat. Disord."},{"key":"218_CR34","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/nrn2555","volume":"10","author":"A Craig","year":"2009","unstructured":"Craig, A. How do you feel--now? The anterior insula and human awareness. Nat. Rev. Neurosci. 10, 59\u201370 (2009).","journal-title":"Nat. Rev. Neurosci."},{"key":"218_CR35","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1016\/j.neuroimage.2008.12.070","volume":"45","author":"K Lovero","year":"2009","unstructured":"Lovero, K., Simmons, A., Aron, J. & Paulus, M. Anterior insular cortex anticipates impending stimulus significance. Neuroimage 45, 976\u2013983 (2009).","journal-title":"Neuroimage"},{"key":"218_CR36","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1038\/npp.2009.129","volume":"35","author":"S Haber","year":"2010","unstructured":"Haber, S. & Knutson, B. The reward circuit: linking primate anatomy and human imaging. Neuropsychopharm 35, 4\u201326 (2010).","journal-title":"Neuropsychopharm"},{"key":"218_CR37","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/S0006-3223(03)00168-9","volume":"54","author":"M Phillips","year":"2003","unstructured":"Phillips, M., Drevets, W. C., Rauch, S. L. & Lane, R. Neurobiology of emotion perception I: The neural basis of normal emotion perception. Biol. Psych. 54, 504\u2013514 (2003).","journal-title":"Biol. Psych."},{"key":"218_CR38","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1002\/cne.20660","volume":"490","author":"J Fudge","year":"2005","unstructured":"Fudge, J., Breibart, M., Danish, M. & Pannoni, V. Insular and gustatory inputs to the caudal ventral striatum in primates. J. Comp. Neurol. 490, 101\u2013118 (2005).","journal-title":"J. Comp. Neurol."},{"key":"218_CR39","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0165-0173(94)00007-C","volume":"20","author":"A Parent","year":"1995","unstructured":"Parent, A. & Hazarati, L.-N. Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res. Brain Res. Rev. 20, 91\u2013127 (1995).","journal-title":"Brain Res. Brain Res. Rev."},{"key":"218_CR40","unstructured":"Craig A. in Handbook of Emotion (eds Lewis, M., Haviland-Jones, J. M. and Barrett, L. F.) The Guildford Press, 272-292 (2008)."},{"key":"218_CR41","doi-asserted-by":"publisher","first-page":"14","DOI":"10.3389\/fnbeh.2013.00003","volume":"7","author":"T Klein","year":"2013","unstructured":"Klein, T., Ullsperger, M. & Danielmeier, C. Error awareness and the insula: links to neurological and psychiatric diseases. Front. Behav. Neurosci. 7, 14 (2013).","journal-title":"Front. Behav. Neurosci."},{"key":"218_CR42","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/j.1749-6632.2011.05990.x","volume":"1125","author":"A Craig","year":"2011","unstructured":"Craig, A. Significance of the insula for the evolution of human awareness of feelings from the body. Ann. NY Acad. Sci. 1125, 72\u201382 (2011).","journal-title":"Ann. NY Acad. Sci."},{"key":"218_CR43","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1016\/j.neuropsychologia.2008.02.031","volume":"46","author":"P Sachdev","year":"2008","unstructured":"Sachdev, P., Mondraty, N., Wen, W., & Gulliford, K. Brains of anorexia nervosa patients process self-images differently from non-self-images: an fMRI study. Neuropsychologia 46, 2161\u20132168 (2008).","journal-title":"Neuropsychologia"},{"key":"218_CR44","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1017\/S0033291709991826","volume":"40","author":"H Mohr","year":"2010","unstructured":"Mohr, H. et al. Separating two components of body image in anorexia nervosa using fMRI. Psychol. Med. 40, 1519\u20131529 (2010).","journal-title":"Psychol. Med."},{"key":"218_CR45","doi-asserted-by":"publisher","first-page":"346","DOI":"10.3389\/fpsyg.2011.00346","volume":"2","author":"R Lowe","year":"2011","unstructured":"Lowe, R., & Ziemke, T. The feeling of action tendencies: on the emotional regulation of goal-directed behavior. Front Psychol 2, 346 (2011).","journal-title":"Front Psychol"},{"key":"218_CR46","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.drugalcdep.2013.05.029","volume":"131","author":"A May","year":"2013","unstructured":"May, A., Stewart, J., Migliorini, R., Tapert, S. F. & Paulus, M. P. Methamphetamine dependent individuals show attenuated brain response to pleasant interoceptive stimuli. Drug Alcohol Depend. 131, 238\u2013246 (2013).","journal-title":"Drug Alcohol Depend."},{"key":"218_CR47","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.drugalcdep.2013.08.015","volume":"133","author":"R Migliorini","year":"2013","unstructured":"Migliorini, R., Stewart, J., May, A., Tapert, S. F. & Paulus, M. P. What do you feel? Adolescent drug and alcohol users show altered brain response to pleasant interoceptive stimuli. Drug Alcohol Depend. 133, 661\u2013668 (2013).","journal-title":"Drug Alcohol Depend."},{"key":"218_CR48","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.drugalcdep.2015.07.009","volume":"154","author":"JL Stewart","year":"2015","unstructured":"Stewart, J. L., May, A. C., Tapert, S. & Paulus, M. Hyperactivation to pleasant interoceptive stimuli characterizes the transition to stimulant addiction. Drug Alcohol Depend. 154, 264\u2013270 (2015).","journal-title":"Drug Alcohol Depend."},{"key":"218_CR49","unstructured":"Wierenga C., et al. Unmotivated to eat: a neural basis for fear of food in anorexia nervosa. In preparation"},{"key":"218_CR50","unstructured":"Cloninger C., Przybeck T., Svrakic D., Wetzel R. in The Temperament and Character Inventory (TCI): A Guide to its Development and Use. 2, Ch. 4, p. 19\u201328, ISBN 0-9642917-1-1 (Center for Psychobiology of Personality, Washington University, St. Louis MO, 1994)."},{"key":"218_CR51","first-page":"401","volume":"33","author":"A Yamamotova","year":"2012","unstructured":"Yamamotova, A., Kmoch, V. & Papezova, H. Role of dehydroepiandrosterone and cortisol in nociceptive sensitivity to thermal pain in anorexia nervosa and healthy women. Neuro. Endocrinol. Lett. 33, 401\u2013405 (2012).","journal-title":"Neuro. Endocrinol. Lett."},{"key":"218_CR52","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1002\/eat.20251","volume":"39","author":"A Wagner","year":"2006","unstructured":"Wagner, A. et al. Personality traits after recovery from eating disorders: Do subtypes differ? Int. J. Eat. Disord. 39, 276\u2013284 (2006).","journal-title":"Int. J. Eat. Disord."},{"key":"218_CR53","first-page":"22","volume":"59","author":"DV Sheehan","year":"1998","unstructured":"Sheehan, D. V. et al. The Mini-International Neuropspychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 59, 22\u201333 (1998). quiz4-57.","journal-title":"J. Clin. Psychiatry"},{"key":"218_CR54","volume-title":"STAI Manual for the State Trait Anxiety Inventory","author":"C Spielberger","year":"1970","unstructured":"Spielberger, C., Gorsuch, R. & Lushene, R. STAI Manual for the State Trait Anxiety Inventory. (Consulting Psychologists Press, Palo Alto, CA, 1970)."},{"key":"218_CR55","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","volume":"4","author":"AT Beck","year":"1961","unstructured":"Beck, A. T., Ward, M., Mendelson, M., Mock, J. & Erbaugh, J. An inventory for measuring depression. Arch. Gen. Psychiatry 4, 561\u2013571 (1961).","journal-title":"Arch. Gen. Psychiatry"},{"key":"218_CR56","unstructured":"Garner D. M. Eating Disorder Inventory-2 Professional Manual (Psychological Assessment Resources, Inc., Odessa FL, 1991)."},{"key":"218_CR57","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/nn.2312","volume":"12","author":"L L\u00f6ken","year":"2009","unstructured":"L\u00f6ken, L., Wessberg, J., Morrison, I., McGlone, F. & Olausson, H. Coding of pleasant touch by unmyelinated afferents in humans. Nat. Neurosci. 12, 547\u2013548 (2009).","journal-title":"Nat. Neurosci."},{"key":"218_CR58","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1038\/nn896","volume":"5","author":"H Olausson","year":"2002","unstructured":"Olausson, H. et al. Unmyelinated tactile afferents signal touch and project to insular cortex. Nat. Neurosci. 5, 900\u2013904 (2002).","journal-title":"Nat. Neurosci."},{"key":"218_CR59","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/0006-8993(93)90968-S","volume":"628","author":"A Vallbo","year":"1993","unstructured":"Vallbo, A., Olausson, H., Wessberg, J. & Norrsell, U. A system of unmyelinated afferents for innocuous mechanoreception in the human skin. Brain Res. 628, 301\u2013304 (1993).","journal-title":"Brain Res."},{"key":"218_CR60","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1006\/cbmr.1996.0014","volume":"29","author":"R Cox","year":"1996","unstructured":"Cox, R. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput. Biomed. Res. 29, 162\u2013173 (1996).","journal-title":"Comput. Biomed. Res."},{"key":"218_CR61","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1016\/j.neuroimage.2011.09.015","volume":"62","author":"M Jenkinson","year":"2012","unstructured":"Jenkinson, M., Beckmann, C., Behrens, T., Woolrich, M. & Smith, S. FSL. Neuroimage 62, 782\u2013790 (2012).","journal-title":"Neuroimage"},{"key":"218_CR62","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/j.neuroimage.2008.09.037","volume":"44","author":"Z Saad","year":"2009","unstructured":"Saad, Z. et al. A new method for improving functional-to-structural MRI alignment using local Pearson correlation. Neuroimage 44, 839\u2013848 (2009).","journal-title":"Neuroimage"},{"key":"218_CR63","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.neuroimage.2004.03.032","volume":"22","author":"F Segonne","year":"2004","unstructured":"Segonne, F. et al. A hybrid approach to the skull stripping problem in MRI. Neuroimage 22, 1060\u20131075 (2004).","journal-title":"Neuroimage"},{"key":"218_CR64","unstructured":"Andersson J., Jenkinson M., Smith S. Non-linear registration, aka spatial normalisation. FMRIB technical report TR07JA2. http:\/\/www.fmrib.ox.ac.uk\/analysis\/techrep\/tr07ja2\/tr07ja2.pdf. 2010"},{"key":"218_CR65","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/S1361-8415(01)00036-6","volume":"5","author":"M Jenkinson","year":"2001","unstructured":"Jenkinson, M. & Smith, S. A global optimisation method for robust affine registration of brain images. Med. Image Anal. 5, 143\u2013156 (2001).","journal-title":"Med. Image Anal."},{"key":"218_CR66","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1037\/0033-2909.110.1.67","volume":"110","author":"S Taylor","year":"1991","unstructured":"Taylor, S. Asymmetrical effects of positive and negative events: the mobilization-minimization hypothesis. Psychol. Bull. 110, 67\u201385 (1991).","journal-title":"Psychol. Bull."},{"key":"218_CR67","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","volume":"31","author":"R Desikan","year":"2006","unstructured":"Desikan, R., Segonne, F., Fischl, B. & Quinn, B. et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 31, 968\u2013980 (2006).","journal-title":"Neuroimage"},{"key":"218_CR68","doi-asserted-by":"publisher","first-page":"7900","DOI":"10.1073\/pnas.1602413113","volume":"113","author":"A Eklund","year":"2016","unstructured":"Eklund, A., Nichols, T. & Knutsson, H. Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates. Proc. Natl Acad. Sci. USA 113, 7900\u20137905 (2016).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"218_CR69","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/nrn.2016.167","volume":"18","author":"R Poldrack","year":"2017","unstructured":"Poldrack, R. et al. Scanning the horizon: towards transparent and reproducible neuroimaging research. Nat. Rev. Neurosci. 18, 115\u2013126 (2017).","journal-title":"Nat. Rev. Neurosci."},{"key":"218_CR70","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1089\/brain.2016.0475","volume":"7","author":"R Cox","year":"2017","unstructured":"Cox, R., Chen, G., Glen, D. R., Reynolds, R. C. & Taylor, P. A. FMRI clustering in AFNI: False-positive rates redux. Brain Connect. 7, 152\u2013171 (2017).","journal-title":"Brain Connect."},{"key":"218_CR71","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/bimj.200810425","volume":"50","author":"T Hothorn","year":"2008","unstructured":"Hothorn, T., Bretz, F. & Westfall, P. Simultaneous inference in general parametric models. Biom. J. 50, 346\u2013363 (2008).","journal-title":"Biom. J."},{"key":"218_CR72","doi-asserted-by":"crossref","unstructured":"Huber P. Robust Estimation of Location Parameter. Ann. Math. Statist. 1964;35: 73\u2013101.","DOI":"10.1214\/aoms\/1177703732"},{"key":"218_CR73","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.neuroimage.2004.12.005","volume":"25","author":"T Nichols","year":"2005","unstructured":"Nichols, T., Brett, M., Anderson, J., Wager, T. & Poline, J. Valid conjunction inference with the minimum statistic. Neuroimage 25, 653\u2013660 (2005).","journal-title":"Neuroimage"},{"key":"218_CR74","doi-asserted-by":"publisher","first-page":"71","DOI":"10.3389\/fnins.2011.00071","volume":"5","author":"M Delgado","year":"2011","unstructured":"Delgado, M., Jou, R. & Phelps, E. Neural systems underlying aversive conditioning in humans with primary and secondary reinforcers. Front. Neurosci. 5, 71 (2011).","journal-title":"Front. Neurosci."},{"key":"218_CR75","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.tics.2009.05.001","volume":"13","author":"T Singer","year":"2009","unstructured":"Singer, T., Critchley, H. & Preuschoff, K. A common role of insula in feelings, empathy and uncertainty. Trends Cogn. Sci. 13, 334\u2013340 (2009).","journal-title":"Trends Cogn. Sci."},{"key":"218_CR76","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1002\/hbm.21154","volume":"32","author":"A Simmons","year":"2011","unstructured":"Simmons, A. et al. Anxiety positive subjects show altered processing in the anterior insula during anticipation of negative stimuli. Hum. Brain. Mapp. 32, 1836\u20131846 (2011).","journal-title":"Hum. Brain. Mapp."},{"key":"218_CR77","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/2045-5380-4-9","volume":"4","author":"SM Gorka","year":"2014","unstructured":"Gorka, S. M., Nelson, B. D., Phan, K. & Shankman, S. Insula response to unpredictable and predictable aversiveness in individuals with panic disorder and comorbid depression. Biol. Mood Anxiety Disord. 4, 9 (2014).","journal-title":"Biol. Mood Anxiety Disord."},{"key":"218_CR78","doi-asserted-by":"crossref","unstructured":"Andrew, D. & Craig, A. in Affective Touch and the Neurophysiology of CT Afferents (eds H. Olausson, J. Wessberg, I. Morrison, F. McGlone) (Springer, New York, NY), 159\u2013173 (2016).","DOI":"10.1007\/978-1-4939-6418-5_9"},{"key":"218_CR79","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.neuron.2013.07.051","volume":"27","author":"V Abraira","year":"2013","unstructured":"Abraira, V. & Ginty, D. The sensory neurons of touch. Neuron 27, 618\u2013639 (2013).","journal-title":"Neuron"},{"key":"218_CR80","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.cell.2016.12.010","volume":"168","author":"V Abraira","year":"2017","unstructured":"Abraira, V. et al. The cellular and synaptic architecture of the mechanosensory dorsal horn. Cell 168, 295\u20133 (2017).","journal-title":"Cell"},{"key":"218_CR81","doi-asserted-by":"crossref","unstructured":"Cecchetto D. F., Saper C. B. in In Central Regulation of Autonomic Function. (eds Loewy A. D. & Spyer K. M.) p 208\u2013223 (Oxford Univ. Press, New York, 1990)","DOI":"10.1093\/oso\/9780195051063.003.0012"},{"key":"218_CR82","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1126\/science.1254229","volume":"346","author":"A Zimmerman","year":"2014","unstructured":"Zimmerman, A., Bai, L. & Ginty, D. The gentle touch receptors of mammalian skin. Science 346, 950\u2013954 (2014).","journal-title":"Science"},{"key":"218_CR83","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1007\/s00429-010-0262-0","volume":"214","author":"V Menon","year":"2010","unstructured":"Menon, V. & Uddin, L. Saliency, switching, attention and control: a network model of insula function. Brain. Struct. Funct. 214, 655\u2013667 (2010).","journal-title":"Brain. Struct. Funct."},{"key":"218_CR84","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.psychres.2016.01.078","volume":"239","author":"L Crucianelli","year":"2016","unstructured":"Crucianelli, L., Cardi, V., Treasure, J., Jenkinson, P. & Fotopoulou, A. The perception of affective touch in anorexia nervosa. Psychiatr. Res. 239, 72\u201378 (2016).","journal-title":"Psychiatr. Res."},{"key":"218_CR85","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1002\/eat.22538","volume":"49","author":"G Frank","year":"2016","unstructured":"Frank, G., Shott, M., Keffler, C. & Cornier, M. Extremes of eating are associated with reduced neural taste discrimination. Int. J. Eat. Disord. 49, 603\u2013612 (2016).","journal-title":"Int. J. Eat. Disord."},{"key":"218_CR86","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.pscychresns.2013.06.010","volume":"214","author":"T Oberndorfer","year":"2013","unstructured":"Oberndorfer, T. et al. Greater anterior insula activation during anticipation of food images in women recovered from anorexia nervosa versus controls. Psychiatry Res. 214, 132\u2013141 (2013).","journal-title":"Psychiatry Res."},{"key":"218_CR87","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.jpsychores.2018.04.005","volume":"110","author":"P Jenkinson","year":"2018","unstructured":"Jenkinson, P., Taylor, L. & Laws, K. Self-reported interoceptive deficits in eating disorders: a meta-analysis of studies using the eating disorder inventory. J. Psychosom. Res. 110, 38\u201345 (2018).","journal-title":"J. Psychosom. Res."},{"key":"218_CR88","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1002\/hbm.23103","volume":"37","author":"I Morrison","year":"2016","unstructured":"Morrison, I. ALE meta-analysis reveals dissociable networks for affective and discriminative aspects of touch. Hum. Brain. Mapp. 37, 1308\u20131320 (2016).","journal-title":"Hum. Brain. Mapp."},{"key":"218_CR89","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.pain.2007.03.001","volume":"133","author":"H Kramer","year":"2007","unstructured":"Kramer, H. et al. Activation of the cortical pain network by soft tactile stimulation after injection of sumatriptan. Pain 133, 72\u201378 (2007).","journal-title":"Pain"},{"key":"218_CR90","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.neubiorev.2008.09.011","volume":"34","author":"H Olausson","year":"2010","unstructured":"Olausson, H., Wessberg, J., Morrison, I., McGlone, F. & Vallbo, A. The neurophysiology of unmyelinated tactile afferents. Neurosci. Biobehav. Rev. 34, 185\u2013191 (2010).","journal-title":"Neurosci. Biobehav. Rev."},{"key":"218_CR91","doi-asserted-by":"publisher","unstructured":"Davidovic M., Starck G., Olausson H. Processing of affective and emotionally neutral tactile stimuli in the insular cortex. Dev. Cogn. Neurosci. pii: S1878\u20139293, 30048-8 (2017) https:\/\/doi.org\/10.1016\/j.dcn.2017.12.006.","DOI":"10.1016\/j.dcn.2017.12.006"},{"key":"218_CR92","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/psyp.12303","volume":"52","author":"J Stewart","year":"2015","unstructured":"Stewart, J., Huavinett, A., May, A., Davenport, P. & Paulus, M. Do you feel alright? Attenuated neural processing of aversive interoceptive stimuli in current stimulant users. Psychophysiol 52, 249\u2013262 (2015).","journal-title":"Psychophysiol"},{"key":"218_CR93","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1152\/jn.2000.84.6.3072","volume":"84","author":"M Delgado","year":"2000","unstructured":"Delgado, M., Nystrom, L., Fissel, C., Noll, D. & Fiez, J. Tracking the hemodynamic responses to reward and punishment in the striatum. J. Neurophysiol. 84, 3072\u20133077 (2000).","journal-title":"J. Neurophysiol."},{"key":"218_CR94","doi-asserted-by":"publisher","first-page":"RC159","DOI":"10.1523\/JNEUROSCI.21-16-j0002.2001","volume":"21","author":"B Knutson","year":"2001","unstructured":"Knutson, B., Adams, C., Fong, G. & Hommer, D. Anticipation of increasing monetary reward selectively recruits nucleus accumbens. J. Neurosci. 21, RC159 (2001).","journal-title":"J. Neurosci."},{"key":"218_CR95","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/wcs.1266","volume":"5","author":"JP Bhanji","year":"2014","unstructured":"Bhanji, J. P. & Delgado, M. R. The social brain and reward: social information processing in the human striatum. Wiley Interdiscip. Rev. Cogn. Sci. 5, 61\u201373 (2014).","journal-title":"Wiley Interdiscip. Rev. Cogn. Sci."},{"key":"218_CR96","doi-asserted-by":"publisher","first-page":"1842","DOI":"10.1176\/appi.ajp.2007.07040575","volume":"164","author":"A Wagner","year":"2007","unstructured":"Wagner, A. et al. Altered reward processing in women recovered from anorexia nervosa. Am. J. Psychiatry 164, 1842\u20131849 (2007).","journal-title":"Am. J. Psychiatry"},{"key":"218_CR97","doi-asserted-by":"publisher","first-page":"46","DOI":"10.3389\/fnbeh.2015.00046","volume":"9","author":"N Sanders","year":"2015","unstructured":"Sanders, N. et al. Altered food-cue processing in chronically ill and recovered women with anorexia nervosa. Front. Behav. Neurosci. 9, 46 (2015).","journal-title":"Front. Behav. Neurosci."},{"key":"218_CR98","doi-asserted-by":"publisher","first-page":"3835","DOI":"10.1002\/hbm.23279","volume":"37","author":"J Cha","year":"2016","unstructured":"Cha, J. et al. Abnormal reward circuitry in anorexia nervosa: a longitudinal, multimodal MRI study. Hum. Brain. Mapp. 37, 3835\u20133846 (2016).","journal-title":"Hum. Brain. Mapp."},{"key":"218_CR99","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1176\/appi.ajp.2016.16060671","volume":"174","author":"M DeGuzman","year":"2017","unstructured":"DeGuzman, M., Shott, M., Yang, T., Riederer, J. & Frank, G. Association of elevated reward prediction error response with weight gain in adolescent anorexia nervosa. Am. J. Psychiatry 174, 557\u2013565 (2017).","journal-title":"Am. J. Psychiatry"},{"key":"218_CR100","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.tics.2015.10.005","volume":"20","author":"S Garfinkel","year":"2016","unstructured":"Garfinkel, S. & Critchley, H. Threat and the body: How the heart supports fear processing. Trends Cogn. Sci. 20, 34\u201346 (2016).","journal-title":"Trends Cogn. Sci."},{"key":"218_CR101","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1002\/erv.2532","volume":"25","author":"T Brown","year":"2017","unstructured":"Brown, T. et al. Psychometric evaluation and norms for the Multidimensional Assessment of Interoceptive Awareness (MAIA) in a clinical eating disorders sample. Eur. Eat. Disord. Rev. 25, 411\u2013416 (2017).","journal-title":"Eur. Eat. Disord. Rev."},{"key":"218_CR102","doi-asserted-by":"publisher","first-page":"484","DOI":"10.3389\/fnhum.2016.00484","volume":"10","author":"O Pollatos","year":"2016","unstructured":"Pollatos, O. et al. Atypical self-focus effect on interoceptive accuracy in anorexia nervosa. Front. Hum. Neurosci. 10, 484 (2016).","journal-title":"Front. Hum. Neurosci."},{"key":"218_CR103","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1111\/sjop.12183","volume":"56","author":"L Emanuelsen","year":"2015","unstructured":"Emanuelsen, L., Drew, R. & Koteles, F. Interoceptive sensitivity, body image dissatisfaction, and body awareness in healthy individuals. Scand. J. Psychol. 56, 167\u2013174 (2015).","journal-title":"Scand. J. Psychol."},{"key":"218_CR104","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1038\/nrn3950","volume":"16","author":"L Barrett","year":"2015","unstructured":"Barrett, L. & Simmons, W. Interoceptive predictions in the brain. Nat. Rev. Neurosci. 16, 419\u2013429 (2015).","journal-title":"Nat. Rev. Neurosci."},{"key":"218_CR105","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/nrn2682","volume":"10","author":"W Kaye","year":"2009","unstructured":"Kaye, W., Fudge, J. & Paulus, M. New insight into symptoms and neurocircuit function of anorexia nervosa. Nat. Rev. Neurosci. 10, 573\u2013584 (2009).","journal-title":"Nat. Rev. Neurosci."},{"key":"218_CR106","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.tins.2013.01.003","volume":"36","author":"W Kaye","year":"2013","unstructured":"Kaye, W., Wierenga, C., Bailer, U., Simmons, A. & Bischoff-Grethe, A. Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa. Trends Neurosci.: Spec. Issue Neural Control Appetite. 36, 110\u2013120 (2013).","journal-title":"Trends Neurosci.: Spec. Issue Neural Control Appetite."},{"key":"218_CR107","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/j.cell.2016.05.033","volume":"166","author":"L Orefice","year":"2016","unstructured":"Orefice, L. et al. Peripheral mechanosensory neuron dysfunction underlies tactile and behavioral deficits in mouse models of ASDs. Cell 166, 299\u2013313 (2016).","journal-title":"Cell"},{"key":"218_CR108","doi-asserted-by":"publisher","DOI":"10.1186\/2040-2392-4-44","volume":"4","author":"K Tchanturia","year":"2013","unstructured":"Tchanturia, K. et al. Exploring autistic traits in anorexia: a clinical study. Mol. Autism 4, 44 (2013).","journal-title":"Mol. Autism"},{"key":"218_CR109","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1037\/0033-2909.133.6.976","volume":"133","author":"N Zucker","year":"2007","unstructured":"Zucker, N. et al. Anorexia nervosa and autism spectrum disorders: guided investigation of social cognitive endophenotypes. Psychol. Bull. 133, 976\u20131006 (2007).","journal-title":"Psychol. Bull."},{"key":"218_CR110","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1097\/00001756-200004270-00019","volume":"11","author":"H Johansen-Berg","year":"2000","unstructured":"Johansen-Berg, H., Christensen, V., Woolrich, M. & Matthews, P. Attention to touch modulates activity in both primary and secondary somatosensory areas. Neuroreport 11, 1237\u20131241 (2000).","journal-title":"Neuroreport"},{"key":"218_CR111","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1016\/S0028-3932(01)00119-1","volume":"39","author":"E Macaluso","year":"2001","unstructured":"Macaluso, E. & Driver, J. Spatial attention and crossmodal interactions between vision and touch. Neuropsychologia 39, 1304\u20131316 (2001).","journal-title":"Neuropsychologia"},{"key":"218_CR112","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113425","volume":"9","author":"C Triscoli","year":"2014","unstructured":"Triscoli, C., Ackerley, R. & Sailer, U. Touch satiety: differential effects of stroking velocity on liking and wanting touch over repetitions. PLoS ONE 9, e113425 (2014).","journal-title":"PLoS ONE"},{"key":"218_CR113","first-page":"19","volume":"6","author":"D Ellingsen","year":"2015","unstructured":"Ellingsen, D., Leknes, S., Loseth, G., Wessberg, J. & Olausson, H. The neurobiology shaping affective touch: expectation, motivation, and meaning in the multisensory context. Front. Psychol. 6, 19 (2015).","journal-title":"Front. Psychol."},{"key":"218_CR114","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1021\/cn5001028","volume":"5","author":"R Bevins","year":"2014","unstructured":"Bevins, R. & Besheer, J. Interoception and learning: import to understanding and treating diseases and psychopathologies. ACS Chem. Neurosci. 5, 624\u2013631 (2014).","journal-title":"ACS Chem. Neurosci."}],"container-title":["Translational Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41398-018-0218-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41398-018-0218-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41398-018-0218-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T08:29:09Z","timestamp":1720513749000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41398-018-0218-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,16]]},"references-count":114,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,12]]}},"alternative-id":["218"],"URL":"https:\/\/doi.org\/10.1038\/s41398-018-0218-3","relation":{},"ISSN":["2158-3188"],"issn-type":[{"value":"2158-3188","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,16]]},"assertion":[{"value":"15 February 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 June 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"161"}}