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To investigate this, we used summary statistics from genome-wide association studies and linkage disequilibrium score regression to calculate a matrix of genetic correlations (\n                    <jats:italic>r<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>gs<\/jats:italic>\n                    <\/jats:sub>\n                    ) for antisocial behavior (ASB), COVID-19, and various health and behavioral traits. After false-discovery rate correction, ASB was genetically correlated with COVID-19 (\n                    <jats:italic>r<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>g<\/jats:italic>\n                    <\/jats:sub>\n                    \u2009=\u20090.51;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20091.54E-02) and 19 other traits. ASB and COVID-19 were both positively genetically correlated with having a noisy workplace, doing heavy manual labor, chronic obstructive pulmonary disease, and genitourinary diseases. ASB and COVID-19 were both inversely genetically correlated with average income, education years, healthspan, verbal reasoning, lifespan, cheese intake, and being breastfed as a baby. But keep in mind that\n                    <jats:italic>r<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>gs<\/jats:italic>\n                    <\/jats:sub>\n                    are not necessarily causal. And, if causal, their prevailing directions of effect (which causes which) are indiscernible from\n                    <jats:italic>r<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>gs<\/jats:italic>\n                    <\/jats:sub>\n                    alone. Moreover, the SNP-heritability (\n                    <jats:inline-formula>\n                      <jats:alternatives>\n                        <jats:tex-math>$$h_g^2$$<\/jats:tex-math>\n                        <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                          <mml:msubsup>\n                            <mml:mrow>\n                              <mml:mi>h<\/mml:mi>\n                            <\/mml:mrow>\n                            <mml:mrow>\n                              <mml:mi>g<\/mml:mi>\n                            <\/mml:mrow>\n                            <mml:mrow>\n                              <mml:mn>2<\/mml:mn>\n                            <\/mml:mrow>\n                          <\/mml:msubsup>\n                        <\/mml:math>\n                      <\/jats:alternatives>\n                    <\/jats:inline-formula>\n                    ) estimates for two measures of COVID-19 were very small, restricting the overlap of genetic variance in absolute terms between ASB and COVID-19. Nonetheless, our findings suggest that those with antisocial tendencies possibly have a higher risk of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) than those without antisocial tendencies. This may have been especially true early in the pandemic before vaccines against SARS-CoV-2 were available and before the emergence of the highly transmissible Omicron variant.\n                  <\/jats:p>","DOI":"10.1038\/s41398-022-01948-4","type":"journal-article","created":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T06:02:54Z","timestamp":1652162574000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Shared genomic architectures of COVID-19 and antisocial behavior"],"prefix":"10.1038","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5817-7226","authenticated-orcid":false,"given":"Charleen D.","family":"Adams","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorim J.","family":"Tielbeek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian B.","family":"Boutwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Broad Antisocial Behavior Consortium","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"1948_CR1","unstructured":"Cohen MA. 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