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All animal procedures were approved by the Animal Ethics Committee of School of Basic Medical Sciences at Fudan University. Human brain samples were obtained from Fudan branch of National Health and Disease Human Brain Tissue Resource Center, the Body Donation Station in Fudan University (Shanghai Red Cross Society). Human postmortem brain tissue from two control and two BD donors of Asian ancestry (Table ) was obtained under ethic approval 2018C001 by the Ethics Committee of School of Basic Medical Sciences at Fudan University. Human caudate paraffin sections of five control and five BD donors of Caucasian ancestry were kindly provided by Douglas-Bell Canada Brain Bank (Table ).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"494"}}