{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:52:33Z","timestamp":1791075153792,"version":"4.1.0"},"reference-count":98,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":46,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100011123","name":"UM | Academic Health Center, University of Minnesota","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["T32TR004385"],"award-info":[{"award-number":["T32TR004385"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["1UM1TR004405"],"award-info":[{"award-number":["1UM1TR004405"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Transl Psychiatry"],"DOI":"10.1038\/s41398-026-04352-4","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:25:41Z","timestamp":1786962341000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Changes in resting-state functional connectivity between large-scale brain networks after an intensive arts intervention for adolescents with depression"],"prefix":"10.1038","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9631-3770","authenticated-orcid":false,"given":"Kathryn R.","family":"Cullen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donovan","family":"Roediger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep","family":"Ba\u015fg\u00f6ze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Padilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanze","family":"Hayee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2107-0038","authenticated-orcid":false,"given":"Bonnie","family":"Klimes-Dougan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Fiecas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2464-6511","authenticated-orcid":false,"given":"Wilma","family":"Koutstaal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2429-0391","authenticated-orcid":false,"given":"Bryon A.","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"4352_CR1","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1016\/j.jadohealth.2012.05.006","volume":"52","author":"LP Spear","year":"2013","unstructured":"Spear LP. Adolescent neurodevelopment. J Adolesc Health. 2013;52:S7\u201313.","journal-title":"J Adolesc Health"},{"key":"4352_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2024.101486","volume":"71","author":"AE Baker","year":"2025","unstructured":"Baker AE, Galv\u00e1n A, Fuligni AJ. The connecting brain in context: How adolescent plasticity supports learning and development. Dev Cogn Neurosci. 2025;71:101486.","journal-title":"Dev Cogn Neurosci"},{"key":"4352_CR3","unstructured":"2021 NSDUH Annual National Report. https:\/\/www.samhsa.gov\/data\/report\/2021-nsduh-annual-national-report (accessed 10 Feb2024)."},{"key":"4352_CR4","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1038\/nrn2513","volume":"9","author":"T Paus","year":"2008","unstructured":"Paus T, Keshavan M, Giedd JN. Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci. 2008;9:947\u201357.","journal-title":"Nat Rev Neurosci"},{"key":"4352_CR5","unstructured":"CDC. https:\/\/wonder.cdc.gov\/controller\/datarequest\/D158;jsessionid=6271CF52137B685D415EE85A3D6E."},{"key":"4352_CR6","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1097\/01.chi.0000240840.63737.1d","volume":"45","author":"G Emslie","year":"2006","unstructured":"Emslie G, Kratochvil C, Vitiello B, Silva S, Mayes T, McNulty S, et al. Treatment for Adolescents with Depression Study (TADS): safety results. J Am Acad Child Adolesc Psychiatry. 2006;45:1440\u201355.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"4352_CR7","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1097\/01.chi.0000237709.35637.c0","volume":"45","author":"J March","year":"2006","unstructured":"March J, Silva S, Vitiello B. The Treatment for Adolescents with Depression Study (TADS): methods and message at 12 weeks. J Am Acad Child Adolesc Psychiatry. 2006;45:1393\u2013403.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"4352_CR8","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1097\/CHI.0b013e31819176f9","volume":"48","author":"BD Kennard","year":"2009","unstructured":"Kennard BD, Silva SG, Tonev S, Rohde P, Hughes JL, Vitiello B, et al. Remission and recovery in the Treatment for Adolescents with Depression Study (TADS): acute and long-term outcomes. J Am Acad Child Adolesc Psychiatry. 2009;48:186\u201395.","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"4352_CR9","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1001\/archgenpsychiatry.2010.150","volume":"68","author":"J Curry","year":"2011","unstructured":"Curry J, Silva S, Rohde P, Ginsburg G, Kratochvil C, Simons A, et al. Recovery and recurrence following treatment for adolescent major depression. Arch Gen Psychiatry. 2011;68:263\u20139.","journal-title":"Arch Gen Psychiatry"},{"key":"4352_CR10","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/s00787-019-01469-4","volume":"30","author":"J Radez","year":"2021","unstructured":"Radez J, Reardon T, Creswell C, Lawrence PJ, Evdoka-Burton G, Waite P. Why do children and adolescents (not) seek and access professional help for their mental health problems? A systematic review of quantitative and qualitative studies. Eur Child Adolesc Psychiatry. 2021;30:183\u2013211.","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"4352_CR11","unstructured":"Fancourt D, Finn S What is the evidence on the role of the arts in improving health and well-being? A scoping review. 2019. https:\/\/apps.who.int\/iris\/handle\/10665\/329834 (accessed 11 May 2023)."},{"key":"4352_CR12","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-023-03226-6","volume":"22","author":"TL Golden","year":"2024","unstructured":"Golden TL, Ordway RW, Magsamen S, Mohanty A, Chen Y, Ng TWC. Supporting youth mental health with arts-based strategies: a global perspective. BMC Med. 2024;22:7.","journal-title":"BMC Med"},{"key":"4352_CR13","doi-asserted-by":"publisher","first-page":"71","DOI":"10.47102\/annals-acadmedsg.V32N1p71","volume":"32","author":"P Thwaite","year":"2003","unstructured":"Thwaite P, Bennett DL, Pynor H, Zigmond H. Art and \u2018the language of well-being\u2019 in adolescent health care. Ann Acad Med Singapore. 2003;32:71\u201377.","journal-title":"Ann Acad Med Singapore"},{"key":"4352_CR14","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1177\/1757913917712283","volume":"137","author":"L Zarobe","year":"2017","unstructured":"Zarobe L, Bungay H. The role of arts activities in developing resilience and mental wellbeing in children and young people a rapid review of the literature. Perspect Public Health. 2017;137:337\u201347.","journal-title":"Perspect Public Health"},{"key":"4352_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-021-03350-8","volume":"21","author":"SM Gaiha","year":"2021","unstructured":"Gaiha SM, Salisbury TT, Usmani S, Koschorke M, Raman U, Petticrew M. Effectiveness of arts interventions to reduce mental-health-related stigma among youth: a systematic review and meta-analysis. BMC Psychiatry. 2021;21:364.","journal-title":"BMC Psychiatry"},{"key":"4352_CR16","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1080\/17533015.2021.1894463","volume":"14","author":"S O\u2019Donnell","year":"2022","unstructured":"O\u2019Donnell S, Lohan M, Oliffe JL, Grant D, Galway K. The acceptability, effectiveness and gender responsiveness of participatory arts interventions in promoting mental health and Wellbeing: a systematic review. Arts Health. 2022;14:186\u2013203.","journal-title":"Arts Health"},{"key":"4352_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2021.114615","volume":"292","author":"EP Block","year":"2022","unstructured":"Block EP, Wong MD, Kataoka SH, Zimmerman FJ. A symphony within: Frequent participation in performing arts predicts higher positive mental health in young adults. Soc Sci Med. 2022;292:114615.","journal-title":"Soc Sci Med"},{"key":"4352_CR18","doi-asserted-by":"publisher","first-page":"147","DOI":"10.2307\/1131372","volume":"65","author":"Z Marini","year":"1994","unstructured":"Marini Z, Case R. The development of abstract reasoning about the physical and social world. Child Dev. 1994;65:147\u201359.","journal-title":"Child Dev"},{"key":"4352_CR19","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/cad.20148","volume":"2016","author":"SW Kleibeuker","year":"2016","unstructured":"Kleibeuker SW, De Dreu CKW, Crone EA. Creativity development in adolescence: Insight from behavior, brain, and training studies: Creativity development in adolescence. New Dir Child Adolesc Dev. 2016;2016:73\u201384.","journal-title":"New Dir Child Adolesc Dev"},{"key":"4352_CR20","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/j.1467-7687.2012.01176.x","volume":"16","author":"SW Kleibeuker","year":"2013","unstructured":"Kleibeuker SW, De Dreu CKW, Crone EA. The development of creative cognition across adolescence: distinct trajectories for insight and divergent thinking. Dev Sci. 2013;16:2\u201312.","journal-title":"Dev Sci"},{"key":"4352_CR21","doi-asserted-by":"crossref","unstructured":"Barbot B, Heuser B Chapter 5 - Creativity and Identity Formation in Adolescence: A Developmental Perspective. In: Karwowski M, Kaufman JC (eds). The Creative Self. San Diego: Academic Press, 2017, pp 87\u201398.","DOI":"10.1016\/B978-0-12-809790-8.00005-4"},{"key":"4352_CR22","doi-asserted-by":"publisher","first-page":"2820","DOI":"10.1016\/j.neuron.2021.06.016","volume":"109","author":"VJ Sydnor","year":"2021","unstructured":"Sydnor VJ, Larsen B, Bassett DS, Alexander-Bloch A, Fair DA, Liston C, et al. Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology. Neuron. 2021;109:2820\u201346.","journal-title":"Neuron"},{"key":"4352_CR23","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1080\/17533015.2018.1534249","volume":"12","author":"H Kennedy","year":"2020","unstructured":"Kennedy H, Marley M, Torres K, Edelblute A, Novins D. \u2018Be creative and you will reach more people\u2019: youth\u2019s experiences participating in an arts-based social action group aimed at mental health stigma reduction. Arts Health. 2020;12:23\u201337.","journal-title":"Arts Health"},{"key":"4352_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjoc.2024.100083","volume":"34","author":"D Jean-Berluche","year":"2024","unstructured":"Jean-Berluche D. Creative expression and mental health. Journal of Creativity. 2024;34:100083.","journal-title":"Journal of Creativity"},{"key":"4352_CR25","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.tics.2011.08.003","volume":"15","author":"V Menon","year":"2011","unstructured":"Menon V. Large-scale brain networks and psychopathology: a unifying triple network model. Trends Cogn Sci. 2011;15:483\u2013506.","journal-title":"Trends Cogn Sci"},{"key":"4352_CR26","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/386326","volume":"2015","author":"H Zheng","year":"2015","unstructured":"Zheng H, Xu L, Xie F, Guo X, Zhang J, Yao L, et al. The altered triple networks interaction in depression under resting state based on graph theory. Biomed Res Int. 2015;2015:386326.","journal-title":"Biomed Res Int"},{"key":"4352_CR27","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1111\/ejn.16249","volume":"59","author":"F-E Beckmann","year":"2024","unstructured":"Beckmann F-E, Gruber H, Seidenbecher S, Schirmer ST, Metzger CD, Tozzi L, et al. Specific alterations of resting-state functional connectivity in the triple network related to comorbid anxiety in major depressive disorder. Eur J Neurosci. 2024;59:1819\u201332.","journal-title":"Eur J Neurosci"},{"key":"4352_CR28","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1176\/jnp.9.3.471","volume":"9","author":"HS Mayberg","year":"1997","unstructured":"Mayberg HS. Limbic-cortical dysregulation: a proposed model of depression. J Neuropsychiatry Clin Neurosci. 1997;9:471\u201381.","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"4352_CR29","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1152\/jn.00327.2021","volume":"127","author":"AP Schmitt","year":"2022","unstructured":"Schmitt AP. Resting-state functional connectivity in adolescents experiencing subclinical and clinical symptoms of depression: a mini-review of recent evidence. J Neurophysiol. 2022;127:146\u20139.","journal-title":"J Neurophysiol"},{"key":"4352_CR30","doi-asserted-by":"publisher","unstructured":"Mac\u00eado MA, Sato JR, Bressan RA, Pan PM Adolescent depression and resting-state fMRI brain networks: a scoping review of longitudinal studies. Rev Bras Psiquiatr 2022; 44. https:\/\/doi.org\/10.47626\/1516-4446-2021-2032.","DOI":"10.47626\/1516-4446-2021-2032"},{"key":"4352_CR31","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1073\/pnas.1713532115","volume":"115","author":"RE Beaty","year":"2018","unstructured":"Beaty RE, Kenett YN, Christensen AP, Rosenberg MD, Benedek M, Chen Q, et al. Robust prediction of individual creative ability from brain functional connectivity. Proc Natl Acad Sci USA. 2018;115:1087\u201392.","journal-title":"Proc Natl Acad Sci USA"},{"key":"4352_CR32","doi-asserted-by":"publisher","DOI":"10.1038\/srep20482","volume":"6","author":"DM Bashwiner","year":"2016","unstructured":"Bashwiner DM, Wertz CJ, Flores RA, Jung RE. Musical creativity \u2018revealed\u2019 in brain structure: Interplay between motor, default mode, and limbic networks. Sci Rep. 2016;6:20482.","journal-title":"Sci Rep"},{"key":"4352_CR33","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abl4294","volume":"8","author":"M Ovando-Tellez","year":"2022","unstructured":"Ovando-Tellez M, Kenett YN, Benedek M, Bernard M, Belo J, Beranger B, et al. Brain connectivity-based prediction of real-life creativity is mediated by semantic memory structure. Sci Adv. 2022;8:eabl4294.","journal-title":"Sci Adv"},{"key":"4352_CR34","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.cortex.2022.08.008","volume":"156","author":"J Lloyd-Cox","year":"2022","unstructured":"Lloyd-Cox J, Chen Q, Beaty RE. The time course of creativity: Multivariate classification of default and executive network contributions to creative cognition over time. Cortex. 2022;156:90\u2013105.","journal-title":"Cortex"},{"key":"4352_CR35","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.cobeha.2018.08.013","volume":"27","author":"RE Beaty","year":"2019","unstructured":"Beaty RE, Seli P, Schacter DL. Network neuroscience of creative cognition: Mapping cognitive mechanisms and individual differences in the creative brain. Curr Opin Behav Sci. 2019;27:22\u201330.","journal-title":"Curr Opin Behav Sci"},{"key":"4352_CR36","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1002\/hbm.23884","volume":"39","author":"RE Beaty","year":"2018","unstructured":"Beaty RE, Chen Q, Christensen AP, Qiu J, Silvia PJ, Schacter DL. Brain networks of the imaginative mind: Dynamic functional connectivity of default and cognitive control networks relates to openness to experience. Hum Brain Mapp. 2018;39:811\u201321.","journal-title":"Hum Brain Mapp"},{"key":"4352_CR37","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.tics.2015.10.004","volume":"20","author":"RE Beaty","year":"2016","unstructured":"Beaty RE, Benedek M, Silvia PJ, Schacter DL. Creative cognition and brain network dynamics. Trends Cogn Sci. 2016;20:87\u201395.","journal-title":"Trends Cogn Sci"},{"key":"4352_CR38","doi-asserted-by":"publisher","first-page":"11206","DOI":"10.1093\/cercor\/bhad356","volume":"33","author":"K Zhuang","year":"2023","unstructured":"Zhuang K, Zeitlen DC, Beaty RE, Vatansever D, Chen Q, Qiu J. Diverse functional interaction driven by control-default network hubs supports creative thinking. Cereb Cortex. 2023;33:11206\u201324.","journal-title":"Cereb Cortex"},{"key":"4352_CR39","unstructured":"Beaty RE The Creative Brain. Cerebrum 2020; 2020. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32206175."},{"key":"4352_CR40","doi-asserted-by":"publisher","unstructured":"Beaty RE, Cortes RA, Merseal HM, Hardiman MM, Green AE Brain networks supporting scientific creative thinking. Psychol Aesthet Creat Arts 2023. https:\/\/doi.org\/10.1037\/aca0000603.","DOI":"10.1037\/aca0000603"},{"key":"4352_CR41","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1038\/s42003-025-07470-9","volume":"8","author":"Q Chen","year":"2025","unstructured":"Chen Q, Kenett YN, Cui Z, Takeuchi H, Fink A, Benedek M, et al. Dynamic switching between brain networks predicts creative ability. Commun Biol. 2025;8:54.","journal-title":"Commun Biol"},{"key":"4352_CR42","first-page":"1","volume":"38","author":"D Zeitlen","year":"2025","unstructured":"Zeitlen D, Zhuang K, Benedek M, Qiu J, Beaty R. More complex cognitive tasks increasingly connect functionally dissimilar brain regions. J Cogn Neurosci. 2025;38:1\u201320.","journal-title":"J Cogn Neurosci"},{"key":"4352_CR43","doi-asserted-by":"publisher","first-page":"1498","DOI":"10.1007\/s11682-019-00077-9","volume":"14","author":"J Sun","year":"2020","unstructured":"Sun J, Zhang Q, Li Y, Meng J, Chen Q, Yang W, et al. Plasticity of the resting-state brain: static and dynamic functional connectivity change induced by divergent thinking training. Brain Imaging Behav. 2020;14:1498\u2013506.","journal-title":"Brain Imaging Behav"},{"key":"4352_CR44","doi-asserted-by":"publisher","first-page":"3375","DOI":"10.1002\/hbm.23246","volume":"37","author":"J Sun","year":"2016","unstructured":"Sun J, Chen Q, Zhang Q, Li Y, Li H, Wei D, et al. Training your brain to be more creative: brain functional and structural changes induced by divergent thinking training. Hum Brain Mapp. 2016;37:3375\u201387.","journal-title":"Hum Brain Mapp"},{"key":"4352_CR45","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.neuroimage.2014.11.014","volume":"105","author":"A Schlegel","year":"2015","unstructured":"Schlegel A, Alexander P, Fogelson SV, Li X, Lu Z, Kohler PJ, et al. The artist emerges: visual art learning alters neural structure and function. Neuroimage. 2015;105:440\u201351.","journal-title":"Neuroimage"},{"key":"4352_CR46","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2024.1484481","volume":"15","author":"CE Strang","year":"2024","unstructured":"Strang CE. Art therapy and neuroscience: evidence, limits, and myths. Front Psychol. 2024;15:1484481.","journal-title":"Front Psychol"},{"key":"4352_CR47","doi-asserted-by":"publisher","first-page":"4028","DOI":"10.1073\/pnas.0800376105","volume":"105","author":"DA Fair","year":"2008","unstructured":"Fair DA, Cohen AL, Dosenbach NUF, Church JA, Miezin FM, Barch DM, et al. The maturing architecture of the brain\u2019s default network. Proc Natl Acad Sci USA. 2008;105:4028\u201332.","journal-title":"Proc Natl Acad Sci USA"},{"key":"4352_CR48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijchp.2025.100650","volume":"25","author":"J-W Chun","year":"2025","unstructured":"Chun J-W, Choi J, Pyeon A, Hu M, Cho H, Choi J-S, et al. Neurodevelopment of the functional connectivity of the salience network in facial emotion recognition from adolescence to adulthood. Int J Clin Health Psychol. 2025;25:100650.","journal-title":"Int J Clin Health Psychol"},{"key":"4352_CR49","doi-asserted-by":"publisher","DOI":"10.1111\/desc.12571","volume":"21","author":"ML Rosen","year":"2018","unstructured":"Rosen ML, Sheridan MA, Sambrook KA, Dennison MJ, Jenness JL, Askren MK, et al. Salience network response to changes in emotional expressions of others is heightened during early adolescence: relevance for social functioning. Dev Sci. 2018;21:e12571.","journal-title":"Dev Sci"},{"key":"4352_CR50","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.dcn.2014.08.002","volume":"10","author":"LE Sherman","year":"2014","unstructured":"Sherman LE, Rudie JD, Pfeifer JH, Masten CL, McNealy K, Dapretto M. Development of the default mode and central executive networks across early adolescence: a longitudinal study. Dev Cogn Neurosci. 2014;10:148\u201359.","journal-title":"Dev Cogn Neurosci"},{"key":"4352_CR51","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1002\/da.22864","volume":"36","author":"KL Burkhouse","year":"2019","unstructured":"Burkhouse KL, Stange JP, Jacobs RH, Bhaumik R, Bessette KL, Peters AT, et al. Developmental changes in resting-state functional networks among individuals with and without internalizing psychopathologies. Depress Anxiety. 2019;36:141\u201352.","journal-title":"Depress Anxiety"},{"key":"4352_CR52","doi-asserted-by":"publisher","first-page":"827","DOI":"10.3389\/fnhum.2014.00827","volume":"8","author":"CE Stevenson","year":"2014","unstructured":"Stevenson CE, Kleibeuker SW, de Dreu CKW, Crone EA. Training creative cognition: adolescence as a flexible period for improving creativity. Front Hum Neurosci. 2014;8:827.","journal-title":"Front Hum Neurosci"},{"key":"4352_CR53","doi-asserted-by":"publisher","unstructured":"Cullen KR, DiMaggio-Potter ME, Klimes-Dougan B, Bernstein GA, Koutstaal W, Reigstad K et al. The impact of a Creativity Camp intervention on depression and well-being in adolescents. Child Psychiatry Hum Dev 2024. https:\/\/doi.org\/10.1007\/s10578-024-01766-3.","DOI":"10.1007\/s10578-024-01766-3"},{"key":"4352_CR54","doi-asserted-by":"publisher","DOI":"10.1186\/s13034-025-00893-6","volume":"19","author":"Y Taniguchi","year":"2025","unstructured":"Taniguchi Y, Costa O, Ortega A, Hayee S, Friedman J, DiMaggio-Potter ME, et al. Personal growth through navigating the world as an artist: a qualitative study of the impact of creativity camp on adolescents with depression. Child Adolesc Psychiatry Ment Health. 2025;19:38.","journal-title":"Child Adolesc Psychiatry Ment Health"},{"key":"4352_CR55","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S1056-4993(18)30610-2","volume":"1","author":"A Angold","year":"1992","unstructured":"Angold A, Costello EJ. Comorbidity in children and adolescents with depression. Child Adolesc Psychiatr Clin N Am. 1992;1:31\u201351.","journal-title":"Child Adolesc Psychiatr Clin N Am"},{"key":"4352_CR56","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1097\/PRA.0000000000000132","volume":"22","author":"TH Melton","year":"2016","unstructured":"Melton TH, Croarkin PE, Strawn JR, McClintock SM. Comorbid anxiety and depressive symptoms in children and adolescents: A systematic review and analysis: A systematic review and analysis. J Psychiatr Pract. 2016;22:84\u201398.","journal-title":"J Psychiatr Pract"},{"key":"4352_CR57","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1176\/appi.ajp.159.1.3","volume":"159","author":"CB Nemeroff","year":"2002","unstructured":"Nemeroff CB. Comorbidity of mood and anxiety disorders: the rule, not the exception?. Am J Psychiatry. 2002;159:3\u20134.","journal-title":"Am J Psychiatry"},{"key":"4352_CR58","doi-asserted-by":"publisher","first-page":"313","DOI":"10.4088\/JCP.09m05305whi","volume":"71","author":"DV Sheehan","year":"2010","unstructured":"Sheehan DV, Sheehan KH, Shytle RD, Janavs J, Bannon Y, Rogers JE, et al. Reliability and validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID). J Clin Psychiatry. 2010;71:313\u201326.","journal-title":"J Clin Psychiatry"},{"key":"4352_CR59","unstructured":"Kovacs M. Children's depression inventory (CDI2): Technical manual. Multi-Health Systems, Incorporated. 2011."},{"key":"4352_CR60","doi-asserted-by":"publisher","DOI":"10.1186\/s13034-017-0160-9","volume":"11","author":"M Aebi","year":"2017","unstructured":"Aebi M, Kuhn C, Banaschewski T, Grimmer Y, Poustka L, Steinhausen H-C, et al. The contribution of parent and youth information to identify mental health disorders or problems in adolescents. Child Adolesc Psychiatry Ment Health. 2017;11:23.","journal-title":"Child Adolesc Psychiatry Ment Health"},{"key":"4352_CR61","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0002-7138(09)62329-3","volume":"22","author":"AE Kazdin","year":"1983","unstructured":"Kazdin AE, French NH, Unis AS, Esveldt-Dawson K. Assessment of childhood depression: correspondence of child and parent ratings. J Am Acad Child Psychiatry. 1983;22:157\u201364.","journal-title":"J Am Acad Child Psychiatry"},{"key":"4352_CR62","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1177\/0734282911426407","volume":"30","author":"Y Bae","year":"2012","unstructured":"Bae Y. Test Review: Children\u2019s Depression Inventory 2 (CDI 2). J Psychoeduc Assess. 2012;30:304\u20138.","journal-title":"J Psychoeduc Assess"},{"key":"4352_CR63","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.dcn.2018.03.001","volume":"32","author":"BJ Casey","year":"2018","unstructured":"Casey BJ, Cannonier T, Conley MI, Cohen AO, Barch DM, Heitzeg MM, et al. The Adolescent Brain Cognitive Development (ABCD) study: Imaging acquisition across 21 sites. Dev Cogn Neurosci. 2018;32:43\u201354.","journal-title":"Dev Cogn Neurosci"},{"key":"4352_CR64","doi-asserted-by":"publisher","unstructured":"Moser J, Nelson SM, Koirala S, Madison TJ, Labonte AK, Carrasco CM, et al. Multi-echo acquisition and thermal denoising advances precision functional imaging. Imaging Neurosci (Camb). 2025;3;https:\/\/doi.org\/10.1162\/imag_a_00426.","DOI":"10.1162\/imag_a_00426"},{"key":"4352_CR65","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2016.44","volume":"3","author":"KJ Gorgolewski","year":"2016","unstructured":"Gorgolewski KJ, Auer T, Calhoun VD, Craddock RC, Das S, Duff EP, et al. The brain imaging data structure, a format for organizing and describing outputs of neuroimaging experiments. Sci Data. 2016;3:160044.","journal-title":"Sci Data"},{"key":"4352_CR66","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1038\/s41592-018-0235-4","volume":"16","author":"O Esteban","year":"2019","unstructured":"Esteban O, Markiewicz CJ, Blair RW, Moodie CA, Isik AI, Erramuzpe A, et al. fMRIPrep: a robust preprocessing pipeline for functional MRI. Nat Methods. 2019;16:111\u20136.","journal-title":"Nat Methods"},{"key":"4352_CR67","doi-asserted-by":"publisher","first-page":"3669","DOI":"10.21105\/joss.03669","volume":"6","author":"E DuPre","year":"2021","unstructured":"DuPre E, Salo T, Ahmed Z, Bandettini P, Bottenhorn K, Caballero-Gaudes C, et al. TE-dependent analysis of multi-echo fMRI with tedana. J Open Source Softw. 2021;6:3669.","journal-title":"J Open Source Softw"},{"key":"4352_CR68","doi-asserted-by":"publisher","DOI":"10.1162\/imag_a_00257","volume":"2","author":"K Mehta","year":"2024","unstructured":"Mehta K, Salo T, Madison TJ, Adebimpe A, Bassett DS, Bertolero M, et al. XCP-D: A robust pipeline for the post-processing of fMRI data. Imaging Neurosci (Camb). 2024;2:imag\u20132\u201300257.","journal-title":"Imaging Neurosci (Camb)"},{"key":"4352_CR69","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.116400","volume":"208","author":"DA Fair","year":"2020","unstructured":"Fair DA, Miranda-Dominguez O, Snyder AZ, Perrone A, Earl EA, Van AN, et al. Correction of respiratory artifacts in MRI head motion estimates. Neuroimage. 2020;208:116400.","journal-title":"Neuroimage"},{"key":"4352_CR70","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.neuroimage.2016.08.009","volume":"154","author":"JD Power","year":"2017","unstructured":"Power JD. A simple but useful way to assess fMRI scan qualities. Neuroimage. 2017;154:150\u20138.","journal-title":"Neuroimage"},{"key":"4352_CR71","doi-asserted-by":"publisher","first-page":"3095","DOI":"10.1093\/cercor\/bhx179","volume":"28","author":"A Schaefer","year":"2018","unstructured":"Schaefer A, Kong R, Gordon EM, Laumann TO, Zuo X-N, Holmes AJ, et al. Local-global parcellation of the human cerebral cortex from intrinsic functional connectivity MRI. Cereb Cortex. 2018;28:3095\u2013114.","journal-title":"Cereb Cortex"},{"key":"4352_CR72","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1152\/jn.00338.2011","volume":"106","author":"BTT Yeo","year":"2011","unstructured":"Yeo BTT, Krienen FM, Sepulcre J, Sabuncu MR, Lashkari D, Hollinshead M, et al. The organization of the human cerebral cortex estimated by intrinsic functional connectivity. J Neurophysiol. 2011;106:1125\u201365.","journal-title":"J Neurophysiol"},{"key":"4352_CR73","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","volume":"52","author":"M Rubinov","year":"2010","unstructured":"Rubinov M, Sporns O. Complex network measures of brain connectivity: uses and interpretations. Neuroimage. 2010;52:1059\u201369.","journal-title":"Neuroimage"},{"key":"4352_CR74","volume-title":"Applied multiple regression\/correlation analysis for the behavioral sciences","author":"J Cohen","year":"2002","unstructured":"Cohen J, Cohen P, West SG, Aiken LS Applied multiple regression\/correlation analysis for the behavioral sciences. 3rd ed. New York, NY: Routledge Member of the Taylor and Francis Group; 2002.","edition":"3rd ed."},{"key":"4352_CR75","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2024.1422361","volume":"18","author":"KS Barnett","year":"2024","unstructured":"Barnett KS, Vasiu F. How the arts heal: a review of the neural mechanisms behind the therapeutic effects of creative arts on mental and physical health. Front Behav Neurosci. 2024;18:1422361.","journal-title":"Front Behav Neurosci"},{"key":"4352_CR76","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1111\/j.1751-7893.2009.00131.x","volume":"3","author":"K Cullen","year":"2009","unstructured":"Cullen K, Klimes-Dougan B, Kumra S, Schulz SC. Paediatric major depressive disorder: neurobiology and implications for early intervention. Early Interv Psychiatry. 2009;3:178\u201388.","journal-title":"Early Interv Psychiatry"},{"key":"4352_CR77","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.neuroscience.2011.10.053","volume":"201","author":"C Liao","year":"2012","unstructured":"Liao C, Feng Z, Zhou D, Dai Q, Xie B, Ji B, et al. Dysfunction of fronto-limbic brain circuitry in depression. Neuroscience. 2012;201:231\u20138.","journal-title":"Neuroscience"},{"key":"4352_CR78","first-page":"426","volume":"8","author":"L Yoon","year":"2023","unstructured":"Yoon L, Rohrsetzer F, Battel L, An\u00e9s M, Manfro PH, Rohde LA, et al. Frontolimbic network topology associated with risk and presence of depression in adolescents: A study using a composite risk score in Brazil. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023;8:426\u201335.","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"4352_CR79","doi-asserted-by":"publisher","first-page":"466","DOI":"10.2174\/1570159X13666150416224801","volume":"13","author":"M Wessa","year":"2015","unstructured":"Wessa M, Lois G. Brain functional effects of psychopharmacological treatment in major depression: A focus on neural circuitry of affective processing. Curr Neuropharmacol. 2015;13:466\u201379.","journal-title":"Curr Neuropharmacol"},{"key":"4352_CR80","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1089\/cap.2015.0232","volume":"26","author":"KR Cullen","year":"2016","unstructured":"Cullen KR, Klimes-Dougan B, Vu DP, Westlund Schreiner M, Mueller BA, Eberly LE, et al. Neural correlates of antidepressant treatment response in adolescents with major depressive disorder. J Child Adolesc Psychopharmacol. 2016;26:705\u201312.","journal-title":"J Child Adolesc Psychopharmacol"},{"key":"4352_CR81","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1093\/bmb\/65.1.193","volume":"65","author":"HS Mayberg","year":"2003","unstructured":"Mayberg HS. Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull. 2003;65:193\u2013207.","journal-title":"Br Med Bull"},{"key":"4352_CR82","doi-asserted-by":"publisher","first-page":"e101035","DOI":"10.1371\/journal.pone.0101035","volume":"9","author":"A Bolwerk","year":"2014","unstructured":"Bolwerk A, Mack-Andrick J, Lang FR, D\u00f6rfler A, Maih\u00f6fner C. How art changes your brain: differential effects of visual art production and cognitive art evaluation on functional brain connectivity. PLoS One. 2014;9:e101035.","journal-title":"PLoS One"},{"key":"4352_CR83","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-17325-6","volume":"12","author":"B Bremer","year":"2022","unstructured":"Bremer B, Wu Q, Mora \u00c1lvarez MG, H\u00f6lzel BK, Wilhelm M, Hell E, et al. Mindfulness meditation increases default mode, salience, and central executive network connectivity. Sci Rep. 2022;12:13219.","journal-title":"Sci Rep"},{"key":"4352_CR84","doi-asserted-by":"publisher","first-page":"461","DOI":"10.3389\/fnhum.2015.00461","volume":"9","author":"A Doll","year":"2015","unstructured":"Doll A, H\u00f6lzel BK, Boucard CC, Wohlschl\u00e4ger AM, Sorg C. Mindfulness is associated with intrinsic functional connectivity between default mode and salience networks. Front Hum Neurosci. 2015;9:461.","journal-title":"Front Hum Neurosci"},{"key":"4352_CR85","doi-asserted-by":"publisher","first-page":"e105780","DOI":"10.1371\/journal.pone.0105780","volume":"9","author":"J Cousijn","year":"2014","unstructured":"Cousijn J, Zanolie K, Munsters RJM, Kleibeuker SW, Crone EA. The relation between resting state connectivity and creativity in adolescents before and after training. PLoS One. 2014;9:e105780.","journal-title":"PLoS One"},{"key":"4352_CR86","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2021.678397","volume":"12","author":"M de Witte","year":"2021","unstructured":"de Witte M, Orkibi H, Zarate R, Karkou V, Sajnani N, Malhotra B, et al. From therapeutic factors to mechanisms of change in the creative arts therapies: a scoping review. Front Psychol. 2021;12:678397.","journal-title":"Front Psychol"},{"key":"4352_CR87","doi-asserted-by":"publisher","first-page":"9878","DOI":"10.1523\/JNEUROSCI.1138-17.2019","volume":"39","author":"WW Seeley","year":"2019","unstructured":"Seeley WW. The salience network: A neural system for perceiving and responding to homeostatic demands. J Neurosci. 2019;39:9878\u201382.","journal-title":"J Neurosci"},{"key":"4352_CR88","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/nrn3857","volume":"16","author":"LQ Uddin","year":"2015","unstructured":"Uddin LQ. Salience processing and insular cortical function and dysfunction. Nat Rev Neurosci. 2015;16:55\u201361.","journal-title":"Nat Rev Neurosci"},{"key":"4352_CR89","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1111\/jcpp.13900","volume":"64","author":"E Williams","year":"2023","unstructured":"Williams E, Glew S, Newman H, Kapka A, Shaughnessy N, Herbert R, et al. Practitioner Review: Effectiveness and mechanisms of change in participatory arts-based programmes for promoting youth mental health and well-being - a systematic review. J Child Psychol Psychiatry. 2023;64:1735\u201364.","journal-title":"J Child Psychol Psychiatry"},{"key":"4352_CR90","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.bandc.2016.12.004","volume":"111","author":"RE Beaty","year":"2017","unstructured":"Beaty RE, Silvia PJ, Benedek M. Brain networks underlying novel metaphor production. Brain Cogn. 2017;111:163\u201370.","journal-title":"Brain Cogn"},{"key":"4352_CR91","doi-asserted-by":"publisher","first-page":"8174","DOI":"10.1073\/pnas.0402680101","volume":"101","author":"N Gogtay","year":"2004","unstructured":"Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaituzis AC, et al. Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci USA. 2004;101:8174\u20139.","journal-title":"Proc Natl Acad Sci USA"},{"key":"4352_CR92","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1038\/13158","volume":"2","author":"JN Giedd","year":"1999","unstructured":"Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos A, et al. Brain development during childhood and adolescence: a longitudinal MRI study. Nat Neurosci. 1999;2:861\u20133.","journal-title":"Nat Neurosci"},{"key":"4352_CR93","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2025.121562","volume":"322","author":"J Lim","year":"2025","unstructured":"Lim J, Mitrai I, Daoutidis P, Stamoulis C. The Adolescent functional connectome is dynamically controlled by a sparse core of cognitive and topological hubs. Neuroimage. 2025;322:121562.","journal-title":"Neuroimage"},{"key":"4352_CR94","doi-asserted-by":"crossref","unstructured":"Marek S, Tervo-Clemmens B, Calabro FJ, Montez DF, Kay BP, Hatoum AS et al. Towards reproducible brain-wide association studies. Cold Spring Harbor Laboratory. 2020; 2020.08.21.257758.","DOI":"10.1101\/2020.08.21.257758"},{"key":"4352_CR95","doi-asserted-by":"publisher","unstructured":"Taniguchi Y, Cullen K The artist mindset: A collaborative autoethnography by a poet and a psychiatrist. J Med Humanit 2025. https:\/\/doi.org\/10.1007\/s10912-025-09970-5.","DOI":"10.1007\/s10912-025-09970-5"},{"key":"4352_CR96","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2019.100706","volume":"40","author":"S Marek","year":"2019","unstructured":"Marek S, Tervo-Clemmens B, Nielsen AN, Wheelock MD, Miller RL, Laumann TO, et al. Identifying reproducible individual differences in childhood functional brain networks: An ABCD study. Dev Cogn Neurosci. 2019;40:100706.","journal-title":"Dev Cogn Neurosci"},{"key":"4352_CR97","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-58176-9","volume":"16","author":"R Kong","year":"2025","unstructured":"Kong R, Spreng RN, Xue A, Betzel RF, Cohen JR, Damoiseaux JS, et al. A network correspondence toolbox for quantitative evaluation of novel neuroimaging results. Nat Commun. 2025;16:2930.","journal-title":"Nat Commun"},{"key":"4352_CR98","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1007\/s10548-019-00744-6","volume":"32","author":"LQ Uddin","year":"2019","unstructured":"Uddin LQ, Yeo BTT, Spreng RN. Towards a universal taxonomy of macro-scale functional human brain networks. Brain Topogr. 2019;32:926\u201342.","journal-title":"Brain Topogr"}],"container-title":["Translational Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41398-026-04352-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41398-026-04352-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41398-026-04352-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:02:29Z","timestamp":1791072149000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41398-026-04352-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":98,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4352"],"URL":"https:\/\/doi.org\/10.1038\/s41398-026-04352-4","relation":{},"ISSN":["2158-3188"],"issn-type":[{"value":"2158-3188","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]},"assertion":[{"value":"3 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}],"article-number":"513"}}