{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T14:47:48Z","timestamp":1792853268645,"version":"4.5.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1038\/s41409-019-0768-x","type":"journal-article","created":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T17:02:48Z","timestamp":1578934968000},"page":"965-973","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["A reproducible and safe at-home allogeneic haematopoietic cell transplant program: first experience in Central and Southern Europe"],"prefix":"10.1038","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4084-8279","authenticated-orcid":false,"given":"Gonzalo","family":"Guti\u00e9rrez-Garc\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Rovira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nacira","family":"Arab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Gallego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"\u00c1ngeles \u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Ayora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadna","family":"Domenech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Borr\u00e0s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5694-0921","authenticated-orcid":false,"given":"Luis","family":"Gerardo Rodr\u00edguez-Lobato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Rosi\u00f1ol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Mar\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Pedraza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Mart\u00ednez-Roca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Carcelero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Dolores Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Teresa Solano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noem\u00ed","family":"de Llobet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Serrahima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miquel","family":"Lozano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Cid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Su\u00e1rez-Lled\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro","family":"Urbano-Ispizua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Fern\u00e1ndez-Avil\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,13]]},"reference":[{"key":"768_CR1","doi-asserted-by":"publisher","first-page":"4855","DOI":"10.1200\/JCO.2006.06.4238","volume":"24","author":"F Fernandez-Aviles","year":"2006","unstructured":"Fernandez-Aviles F, Carreras E, Urbano-Ispizua A, Rovira M, Martinez C, Gaya A, et al. Case-control comparison of at-home to total hospital care for autologous stem-cell transplantation for hematologic malignancies. J Clin Oncol. 2006;24:4855\u201361. https:\/\/doi.org\/10.1200\/JCO.2006.06.4238.","journal-title":"J Clin Oncol"},{"key":"768_CR2","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.bbmt.2017.09.021","volume":"24","author":"M Martino","year":"2018","unstructured":"Martino M, Ciavarella S, De Summa S, Russo L, Meliambro N, Imbalzano L, et al. A comparative assessment of quality of life in patients with multiple myeloma undergoing autologous stem cell transplantation through an outpatient and inpatient model. Biol Blood Marrow Transpl. 2018;24:608\u201313. https:\/\/doi.org\/10.1016\/j.bbmt.2017.09.021.","journal-title":"Biol Blood Marrow Transpl"},{"key":"768_CR3","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1038\/bmt.2015.46","volume":"50","author":"TM Graff","year":"2015","unstructured":"Graff TM, Singavi AK, Schmidt W, Eastwood D, Drobyski WR, Horowitz M, et al. Safety of outpatient autologous hematopoietic cell transplantation for multiple myeloma and lymphoma. Bone Marrow Transpl. 2015;50:947\u201353. https:\/\/doi.org\/10.1038\/bmt.2015.46.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR4","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s00277-006-0149-6","volume":"85","author":"C Leger","year":"2006","unstructured":"Leger C, Sabloff M, McDiarmid S, Bence-Bruckler I, Atkins H, Bredeson C, et al. Outpatient autologous hematopoietic stem cell transplantation for patients with relapsed follicular lymphoma. Ann Hematol. 2006;85:723\u201329. https:\/\/doi.org\/10.1007\/s00277-006-0149-6.","journal-title":"Ann Hematol"},{"key":"768_CR5","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.bbmt.2011.08.001","volume":"18","author":"UD Bayraktar","year":"2012","unstructured":"Bayraktar UD, Champlin RE, Ciurea SO. Progress in haploidentical stem cell transplantation. Biol Blood Marrow Transpl. 2012;18:372\u201380. https:\/\/doi.org\/10.1016\/j.bbmt.2011.08.001. e-pub ahead of print 2011\/10\/05.","journal-title":"Biol Blood Marrow Transpl"},{"key":"768_CR6","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.bbmt.2017.10.035","volume":"24","author":"M Cirillo","year":"2018","unstructured":"Cirillo M, Tan P, Sturm M, Cole C. Cellular immunotherapy for hematologic malignancies: beyond bone marrow transplantation. Biol Blood Marrow Transpl. 2018;24:433\u201342. https:\/\/doi.org\/10.1016\/j.bbmt.2017.10.035. e-pub ahead of print 2017\/11\/06.","journal-title":"Biol Blood Marrow Transpl"},{"key":"768_CR7","doi-asserted-by":"publisher","first-page":"2091","DOI":"10.1056\/NEJMoa1004383","volume":"363","author":"TA Gooley","year":"2010","unstructured":"Gooley TA, Chien JW, Pergam SA, Hingorani S, Sorror ML, Boeckh M, et al. Reduced mortality after allogeneic hematopoietic-cell transplantation. N. Engl J Med. 2010;363:2091\u2013101. https:\/\/doi.org\/10.1056\/NEJMoa1004383. e-pub ahead of print 2010\/11\/26.","journal-title":"N. Engl J Med"},{"key":"768_CR8","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1038\/sj.bmt.1705096","volume":"36","author":"BM Svahn","year":"2005","unstructured":"Svahn BM, Ringden O, Remberger M. Long-term follow-up of patients treated at home during the pancytopenic phase after allogeneic haematopoietic stem cell transplantation. Bone Marrow Transpl. 2005;36:511\u201316. https:\/\/doi.org\/10.1038\/sj.bmt.1705096. e-pub ahead of print 2005\/07\/19.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR9","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.bbmt.2012.10.011","volume":"19","author":"O Ringden","year":"2013","unstructured":"Ringden O, Remberger M, Holmberg K, Edeskog C, Wikstrom M, Eriksson B, et al. Many days at home during neutropenia after allogeneic hematopoietic stem cell transplantation correlates with low incidence of acute graft-versus-host disease. Biol Blood Marrow Transpl. 2013;19:314\u201320. https:\/\/doi.org\/10.1016\/j.bbmt.2012.10.011.","journal-title":"Biol Blood Marrow Transpl"},{"key":"768_CR10","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1038\/bmt.2009.330","volume":"45","author":"S McDiarmid","year":"2010","unstructured":"McDiarmid S, Hutton B, Atkins H, Bence-Bruckler I, Bredeson C, Sabri E, et al. Performing allogeneic and autologous hematopoietic SCT in the outpatient setting: effects on infectious complications and early transplant outcomes. Bone Marrow Transpl. 2010;45:1220\u20136. https:\/\/doi.org\/10.1038\/bmt.2009.330.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR11","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1038\/bmt.2009.234","volume":"45","author":"SR Solomon","year":"2010","unstructured":"Solomon SR, Matthews RH, Barreras AM, Bashey A, Manion KL, McNatt K, et al. Outpatient myeloablative allo-SCT: a comprehensive approach yields decreased hospital utilization and low TRM. Bone Marrow Transpl. 2010;45:468\u201375. https:\/\/doi.org\/10.1038\/bmt.2009.234.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR12","doi-asserted-by":"publisher","unstructured":"Bergkvist K, Fossum B, Johansson UB, Mattsson J, Larsen J Patients' experiences of different care settings and a new life situation after allogeneic haematopoietic stem cell transplantation. Eur J Cancer Care. 2018; 27. https:\/\/doi.org\/10.1111\/ecc.12672.","DOI":"10.1111\/ecc.12672"},{"key":"768_CR13","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.bbmt.2018.12.069","volume":"25","author":"GS Guru Murthy","year":"2019","unstructured":"Guru Murthy GS, Hari PN, Szabo A, Pasquini M, Narra R, Khan M, et al. Outcomes of reduced-intensity conditioning allogeneic hematopoietic cell transplantation performed in the inpatient versus outpatient setting. Biol Blood Marrow Transpl. 2019;25:827\u201333. https:\/\/doi.org\/10.1016\/j.bbmt.2018.12.069.","journal-title":"Biol Blood Marrow Transpl"},{"key":"768_CR14","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1002\/ajh.1051","volume":"66","author":"GJ Ruiz-Arguelles","year":"2001","unstructured":"Ruiz-Arguelles GJ, Gomez-Almaguer D, Ruiz-Arguelles A, Gonzalez-Llano O, Cantu OG, Jaime-Perez JC. Results of an outpatient-based stem cell allotransplant program using nonmyeloablative conditioning regimens. Am J Hematol. 2001;66:241\u20134. https:\/\/doi.org\/10.1002\/ajh.1051.","journal-title":"Am J Hematol"},{"key":"768_CR15","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1097\/TP.0b013e31816a3267","volume":"85","author":"BM Svahn","year":"2008","unstructured":"Svahn BM, Remberger M, Heijbel M, Martell E, Wikstrom M, Eriksson B, et al. Case-control comparison of at-home and hospital care for allogeneic hematopoietic stem-cell transplantation: the role of oral nutrition. Transplantation. 2008;85:1000\u20137. https:\/\/doi.org\/10.1097\/TP.0b013e31816a3267.","journal-title":"Transplantation"},{"key":"768_CR16","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1007\/s12185-017-2363-5","volume":"107","author":"O Ringden","year":"2018","unstructured":"Ringden O, Sadeghi B, Moretti G, Finnbogadottir S, Eriksson B, Mattsson J, et al. Long-term outcome in patients treated at home during the pancytopenic phase after allogeneic haematopoietic stem cell transplantation. Int J Hematol. 2018;107:478\u201385. https:\/\/doi.org\/10.1007\/s12185-017-2363-5.","journal-title":"Int J Hematol"},{"key":"768_CR17","doi-asserted-by":"publisher","DOI":"10.1186\/cc5713","volume":"11","author":"RL Mehta","year":"2007","unstructured":"Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11:R31. https:\/\/doi.org\/10.1186\/cc5713.","journal-title":"Crit Care"},{"key":"768_CR18","doi-asserted-by":"publisher","first-page":"2912","DOI":"10.1182\/blood-2005-05-2004","volume":"106","author":"ML Sorror","year":"2005","unstructured":"Sorror ML, Maris MB, Storb R, Baron F, Sandmaier BM, Maloney DG, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005;106:2912\u20139. https:\/\/doi.org\/10.1182\/blood-2005-05-2004.","journal-title":"Blood"},{"key":"768_CR19","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1038\/bmt.2009.359","volume":"45","author":"L Scrucca","year":"2010","unstructured":"Scrucca L, Santucci A, Aversa F. Regression modeling of competing risk using R: an in depth guide for clinicians. Bone Marrow Transpl. 2010;45:1388\u201395. https:\/\/doi.org\/10.1038\/bmt.2009.359.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR20","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/sj.bmt.1705727","volume":"40","author":"L Scrucca","year":"2007","unstructured":"Scrucca L, Santucci A, Aversa F. Competing risk analysis using R: an easy guide for clinicians. Bone Marrow Transpl. 2007;40:381\u20137. https:\/\/doi.org\/10.1038\/sj.bmt.1705727.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR21","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.3324\/haematol.2013.100784","volume":"99","author":"J Delgado","year":"2014","unstructured":"Delgado J, Pereira A, Villamor N, Lopez-Guillermo A, Rozman C. Survival analysis in hematologic malignancies: recommendations for clinicians. Haematologica. 2014;99:1410\u201320. https:\/\/doi.org\/10.3324\/haematol.2013.100784. e-pub ahead of print 2014\/09\/02.","journal-title":"Haematologica"},{"key":"768_CR22","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1038\/sj.bmt.1702672","volume":"26","author":"BM Svahn","year":"2000","unstructured":"Svahn BM, Bjurman B, Myrback KE, Aschan J, Ringden O. Is it safe to treat allogeneic stem cell transplant recipients at home during the pancytopenic phase? A pilot trial. Bone Marrow Transpl. 2000;26:1057\u201360. https:\/\/doi.org\/10.1038\/sj.bmt.1702672.","journal-title":"Bone Marrow Transpl"},{"key":"768_CR23","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1111\/tid.12225","volume":"16","author":"JH Kim","year":"2014","unstructured":"Kim JH, Goulston C, Zangari M, Tricot G, Boyer MW, Hanson KE. Impact of a change in antibacterial prophylaxis on bacteremia and hospitalization rates following outpatient autologous peripheral blood stem cell transplantation for multiple myeloma. Transpl Infect Dis. 2014;16:421\u20139. https:\/\/doi.org\/10.1111\/tid.12225. e-pub ahead of print 2014\/05\/07.","journal-title":"Transpl Infect Dis"},{"key":"768_CR24","doi-asserted-by":"publisher","first-page":"e46220","DOI":"10.1371\/journal.pone.0046220","volume":"7","author":"A Hamadah","year":"2012","unstructured":"Hamadah A, Schreiber Y, Toye B, McDiarmid S, Huebsch L, Bredeson C, et al. The use of intravenous antibiotics at the onset of neutropenia in patients receiving outpatient-based hematopoietic stem cell transplants. PLoS ONE. 2012;7:e46220. https:\/\/doi.org\/10.1371\/journal.pone.0046220.","journal-title":"PLoS One"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41409-019-0768-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41409-019-0768-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41409-019-0768-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:16:30Z","timestamp":1684617390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41409-019-0768-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,13]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["768"],"URL":"https:\/\/doi.org\/10.1038\/s41409-019-0768-x","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,13]]},"assertion":[{"value":"23 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"GGG received honoraria from Jazz Pharmaceuticals and MSD and grants from Pfizer, Jazz Pharmaceuticals, and Gilead. LR received honoraria from Janssen, Celgene, Amgen, and Takeda. The other authors have no conflicts of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}