{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T13:34:48Z","timestamp":1758893688590,"version":"3.37.3"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T00:00:00Z","timestamp":1642118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T00:00:00Z","timestamp":1642118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>According to the Standards of the World Marrow Donor Association (WMDA) 2020 [1] unrelated stem cell donor registries are responsible for compliance of their donor centres with these Standards. To ensure high stem cell product quality and high standards for safety and satisfaction of voluntary unrelated stem cell donors, we present here guidelines for audits of donor centres (DC) that can be used by new and established donor registries. They have been developed for registries relying on independent national or international DCs for the recruitment and management of Unrelated Donors (UD) for verification typing (VT)\/extended tying (ET), work up processes and Hemopoietic Progenitor Cell (HPC) donation. The main goal of these guidelines is to support registries in verifying and auditing their affiliated DCs to ensure they are compliant with the WMDA Standards, as well as WMDA recommendations. We define the general requirements and recommendations for collaboration with the DC and guidelines to manage the UD, step by step from recruitment to follow-up. We also provide a checklist, intended to serve as a resource for auditors performing an audit at a DC.<\/jats:p>","DOI":"10.1038\/s41409-022-01563-3","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T09:03:43Z","timestamp":1642151023000},"page":"466-472","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Audit of donor centre: guidelines by the World Marrow Donor Association Quality and Regulation Working Group"],"prefix":"10.1038","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1677-6877","authenticated-orcid":false,"given":"Maren","family":"Weber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoletta","family":"Sacchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherry","family":"Haun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Tistl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirasine","family":"Sengomona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2636-9290","authenticated-orcid":false,"given":"Salmah Mahmood","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"K\u00fcrsteiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolin","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Wuchter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,14]]},"reference":[{"key":"1563_CR1","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1038\/bmt.2012.98","volume":"48","author":"AH Schmidt","year":"2013","unstructured":"Schmidt AH, Amer B, Halet M, Hildebrand S, Sacchi N. Qualifications and training of adult stem cell donor recruiters: recommendations by the World Marrow Donor Association. Bone Marrow Transpl. 2013;48:148\u201350. https:\/\/doi.org\/10.1038\/bmt.2012.98.","journal-title":"Bone Marrow Transpl"},{"key":"1563_CR2","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1038\/sj.bmt.1703851","volume":"31","author":"A Rosenmayr","year":"2003","unstructured":"Rosenmayr A, Hartwell L, Egeland T.Ethics Working Group of the World Marrow Donor Association. Informed consent\u2013suggested procedures for informed consent for unrelated haematopoietic stem cell donors at various stages of recruitment, donor evaluation, and donor workup. Bone Marrow Transpl. 2003;31:539\u201345. https:\/\/doi.org\/10.1038\/sj.bmt.1703851.","journal-title":"Bone Marrow Transpl"},{"key":"1563_CR3","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/sj.bmt.1704323","volume":"33","author":"R Bakken","year":"2004","unstructured":"Bakken R, van Walraven AM, Egeland T, Ethics Working Group of the World Marrow Donor A. Donor commitment and recipient needs. Bone Marrow Transpl. 2004;33:225\u201330.","journal-title":"Bone Marrow Transpl"},{"key":"1563_CR4","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1038\/bmt.2014.67","volume":"49","author":"RN Lown","year":"2014","unstructured":"Lown RN, Philippe J, Navarro W, van Walraven SM, Philips-Johnson L, Fechter M. et al. World Marrow Donor Association Clinical Working Group Committee. Unrelated adult stem cell donor medical suitability: recommendations from the World Marrow Donor Association Clinical Working Group Committee. Bone Marrow Transpl. 2014;49:880\u20136. https:\/\/doi.org\/10.1038\/bmt.2014.67.","journal-title":"Bone Marrow Transpl"},{"key":"1563_CR5","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1159\/000485040","volume":"44","author":"JK Neller","year":"2017","unstructured":"Neller JK, Ashford P, van Veen C, Humpe A. Global Registration Identifier for Donors (GRID) of Hematopoietic Stem Cells: Road to Automation and Safety. Transfus Med Hemother. 2017;44:407\u201313. https:\/\/doi.org\/10.1159\/000485040.","journal-title":"Transfus Med Hemother"},{"key":"1563_CR6","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1038\/s41409-018-0252-z","volume":"54","author":"E Lara-Weisshaupt","year":"2019","unstructured":"Lara-Weisshaupt E, Tistl I, Hale K, Torosian T, Schlaphoff T, Manor S. et al. Audits of collection and apheresis centers: guidelines by the World Marrow Donor Association Working Group Quality and Regulation. Bone Marrow Transpl. 2019;54:244\u201357. https:\/\/doi.org\/10.1038\/s41409-018-0252-z.","journal-title":"Bone Marrow Transpl"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41409-022-01563-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41409-022-01563-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41409-022-01563-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T09:11:26Z","timestamp":1646817086000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41409-022-01563-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,14]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["1563"],"URL":"https:\/\/doi.org\/10.1038\/s41409-022-01563-3","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"type":"print","value":"0268-3369"},{"type":"electronic","value":"1476-5365"}],"subject":[],"published":{"date-parts":[[2022,1,14]]},"assertion":[{"value":"18 June 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}