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In a retrospective analysis of registry-data of the European Society for Blood and Marrow Transplantation we analyzed 55 patients aged &lt;\u200918 years who received allogeneic (<jats:italic>N<\/jats:italic>\u2009=\u200946) or autologous (<jats:italic>N<\/jats:italic>\u2009=\u20099) HSCT for PTCL. Median age at HSCT was 13.9 years; 33 patients (60%) were in first remission, and 6 (19%) in progression at HSCT. Conditioning was myeloablative in 87% of the allogeneic HSCTs and in 27 (58.7%) based on total body irradiation. After allogeneic HSCT the 5-year overall- and progression-free survival was 58.9% (95% CI 42.7\u201371.9) and 52.6% (95% CI 36.8\u201366.1), respectively. 5-year relapse incidence was 27.6% (95% CI 15.1\u201341.6), the non-relapse mortality rate was 19.8% (95% CI 9.7\u201332.6). Five of the six patients with progression at HSCT died. Seven of nine patients after autologous HSCT were alive and disease-free at last follow-up. Our data suggest a role of allogeneic HSCT in consolidation-treatment of patients with high-risk disease, who reach at least partial remission after primary- or relapse-therapy, whereas patients with therapy-refractory or progressive disease prior to transplantation do not profit from HSCT.<\/jats:p>","DOI":"10.1038\/s41409-024-02226-1","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T17:02:33Z","timestamp":1707411753000},"page":"604-614","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Hematopoietic stem cell transplantation for pediatric patients with non-anaplastic peripheral T-cell lymphoma. 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