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The recipient, a man with advanced Burkitt lymphoma, is in remission and alive. In the next 40 years transplants of blood-derived progenitor cells have become the most common graft for auto- and allotransplants. The rapid hematopoietic recovery after blood cell-derived grafts is associated with fewer short-term complications and better outcomes in many settings compared with bone marrow-derived grafts but may be associated with more graft-\n                    <jats:italic>versus<\/jats:italic>\n                    -host disease (G\n                    <jats:italic>v<\/jats:italic>\n                    HD) after allotransplants. Using blood-derived grafts also reduced costs, enabled the development of cell-based immune therapy and in vitro manipulation of blood-derived cells for gene and chimeric antigen receptor (CAR)-T-cell therapies.\n                  <\/jats:p>","DOI":"10.1038\/s41409-026-02865-6","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T17:51:06Z","timestamp":1776189066000},"page":"663-667","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Blood cell-derived transplants at 40"],"prefix":"10.1038","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1656-0833","authenticated-orcid":false,"given":"Anthony D.","family":"Ho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7429-8570","authenticated-orcid":false,"given":"Peter","family":"Dreger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Juttner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert Peter","family":"Gale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"2865_CR1","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1182\/blood.V67.2.529.529","volume":"67","author":"M K\u00f6rbling","year":"1986","unstructured":"K\u00f6rbling M, D\u00f6rken B, Ho AD, Pezzutto A, Hunstein W, Fliedner TM. 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