{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T18:30:27Z","timestamp":1754159427050,"version":"3.41.2"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Br Dent J"],"published-print":{"date-parts":[[2025,7,25]]},"DOI":"10.1038\/s41415-025-8722-3","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T08:55:05Z","timestamp":1753433705000},"page":"109-114","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metastatic melanoma posing as periapical pathology: key features and learning points"],"prefix":"10.1038","volume":"239","author":[{"given":"Muhammed Bilaal","family":"Mirza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaspreet","family":"Virdee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonita","family":"Koshal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"8722_CR5922","unstructured":"Melanoma UK. Overview of melanoma. 2016. Available at https:\/\/www.melanomauk.org.uk\/overview-of-melanoma (accessed October 2024)."},{"key":"8722_CR5925","doi-asserted-by":"crossref","unstructured":"Brenner M, Hearing V J. The protective role of melanin against UV damage in human skin. Photochem Photobiol 2007; 84: 539-549.","DOI":"10.1111\/j.1751-1097.2007.00226.x"},{"key":"8722_CR5927","unstructured":"American Cancer Society. What causes melanoma skin cancer? 2023. Available at https:\/\/www.cancer.org\/cancer\/types\/melanoma-skin-cancer\/causes-risks-prevention\/what-causes.html (accessed October 2024)."},{"key":"8722_CR5930","unstructured":"Cancer Research UK. Melanoma skin cancer statistics. Available at https:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/melanoma-skin-cancer#heading-Zero (accessed October 2024)."},{"key":"8722_CR5933","unstructured":"Cancer Research UK. What is melanoma skin cancer? Available at https:\/\/www.cancerresearchuk.org\/about-cancer\/melanoma\/about (accessed October 2024)."},{"key":"8722_CR5937","doi-asserted-by":"crossref","unstructured":"Munde A D, Karle R R, Biradar S, Mishra S. Metastatic malignant melanoma: a case of metastasis from foot to mandibular anterior region. J Cancer Res Ther 2022; 18: 849-852.","DOI":"10.4103\/jcrt.JCRT_1123_20"},{"key":"8722_CR5939","doi-asserted-by":"crossref","unstructured":"Drodge D R, Staines K, Shipley D. Skin cancer - what general dental practitioners should look for. Br Dent J 2024; 236: 279-283.","DOI":"10.1038\/s41415-024-7084-6"},{"key":"8722_CR5941","doi-asserted-by":"crossref","unstructured":"Sibai L, Kudsi Z. Facial skin lesions dentists should know. Dent Update 2015; 42: 520-524.","DOI":"10.12968\/denu.2015.42.6.520"},{"key":"8722_CR5943","doi-asserted-by":"crossref","unstructured":"Main B, Felstead A, Hughes C, Thomas S. A guide to skin cancer of the face for the dental team. Dent Update 2014; 41: 111-118.","DOI":"10.12968\/denu.2014.41.2.111"},{"key":"8722_CR5945","unstructured":"Matthews N H, Li W-Q, Qureshi A A, Weinstock M A, Cho E. Epidemiology of melanoma. In Ward W H, Farma J M (eds) Cutaneous Melanoma: Etiology and Therapy. Brisbane: Codon Publications, 2017."},{"key":"8722_CR5948","doi-asserted-by":"crossref","unstructured":"Steel B J. Skin cancer for dental professionals. BDJ Team 2014; DOI: 10.1038\/bdjteam.2014.93.","DOI":"10.1038\/bdjteam.2014.93"},{"key":"8722_CR5950","unstructured":"Zito P M, Brizuela M, Mazzoni T. Oral Melanoma. Treasure Island: StatPearls Publishing, 2020."},{"key":"8722_CR5952","doi-asserted-by":"crossref","unstructured":"Cymerman R M, Shao Y, Wang K et al. De novo vs nevus-associated melanomas: differences in associations with prognostic indicators and survival. J Natl Cancer Inst 2016; DOI: 10.1093\/jnci\/djw121.","DOI":"10.1093\/jnci\/djw121"},{"key":"8722_CR5955","doi-asserted-by":"crossref","unstructured":"Tuong W, Cheng L S, Armstrong A W. Melanoma: epidemiology, diagnosis, treatment, and outcomes. Dermatol Clin 2012; 30: 113-124.","DOI":"10.1016\/j.det.2011.08.006"},{"key":"8722_CR5957","unstructured":"Rastrelli M, Tropea S, Rossi C R, Alaibac M. Melanoma: epidemiology, risk factors, pathogenesis, diagnosis and classification. In Vivo 2014; 28: 1005-1011."},{"key":"8722_CR5959","doi-asserted-by":"crossref","unstructured":"Sapp J P, Eversole L R, Wysocki G P. Epithelial disorders. In Sapp J P, Eversole L R, Wysocki G P (eds) Contemporary Oral and Maxillofacial Pathology. 2nd ed. St Louis: Mosby, 2004.","DOI":"10.1016\/B978-0-323-01723-7.50011-2"},{"key":"8722_CR5961","doi-asserted-by":"crossref","unstructured":"Misra S R, Tripathy U R, Das R, Mohanty N. Oral malignant melanoma: a rarity! BMJ Case Rep 2021; DOI: 10.1136\/bcr-2021-246045.","DOI":"10.1136\/bcr-2021-246045"},{"key":"8722_CR5963","doi-asserted-by":"crossref","unstructured":"Bakshi N, Mukherjee S, Chauhan Y S. Surgical decision making in oral mucosal melanoma with lymphadenopathy: review of literature. Int J Head Neck Surg 2014; 5: 135-139.","DOI":"10.5005\/jp-journals-10001-1199"},{"key":"8722_CR5966","doi-asserted-by":"crossref","unstructured":"Kumar G, Manjunatha B. Metastatic tumors to the jaws and oral cavity. J Oral Maxillofac Pathol 2013; 17: 71-75.","DOI":"10.4103\/0973-029X.110737"},{"key":"8722_CR5968","unstructured":"UK Government. Delivering better oral health: an evidence-based toolkit for prevention. 2021. Available at https:\/\/www.gov.uk\/government\/publications\/delivering-better-oral-health-an-evidence-based-toolkit-for-prevention (accessed June 2025)."},{"key":"8722_CR5972","unstructured":"National Institute for Health and Care Excellence. Suspected cancer: recognition and referral. 2023. Available at https:\/\/www.nice.org.uk\/guidance\/ng12\/chapter\/Recommendations-organised-by-site-of-cancer#skin-cancers (accessed October 2024)."},{"key":"8722_CR5975","doi-asserted-by":"crossref","unstructured":"Rezaei S J, Eid E, Tang J Y, Kurian A W, Kwong B Y, Linos E. Incidence of nonkeratinocyte skin cancer after breast cancer radiation therapy. JAMA Netw Open 2024; DOI: 10.1001\/jamanetworkopen.2024.1632.","DOI":"10.1001\/jamanetworkopen.2024.1632"},{"key":"8722_CR5977","doi-asserted-by":"crossref","unstructured":"Omland S H, Gniadecki R, H\u00e6dersdal M, Helweg-Larsen J, Omland L H. Skin cancer risk in hematopoietic stem-cell transplant recipients compared with background population and renal transplant recipients. JAMA Dermatol 2016; 152: 177-183.","DOI":"10.1001\/jamadermatol.2015.3902"},{"key":"8722_CR5979","unstructured":"The Royal Marsden NHS Foundation Trust. Skin cancer: diagnosis. Available at https:\/\/www.royalmarsden.nhs.uk\/information-gps\/gp-resources\/skin-cancer\/skin-cancer-diagnosis (accessed October 2024)."},{"key":"8722_CR5983","doi-asserted-by":"crossref","unstructured":"Morse G A, Haque M S, Sharland M R, Burke F J T. The use of clinical photography by UK general dental practitioners. Br Dent J 2010; 208: 14-15.","DOI":"10.1038\/sj.bdj.2010.24"},{"key":"8722_CR5985","doi-asserted-by":"crossref","unstructured":"Lin I, Datta M, Laronde D M, Rosin M P, Chan B. Intraoral photography recommendations for remote risk assessment and monitoring of oral mucosal lesions. Int Dent J 2021; 71: 384-389.","DOI":"10.1016\/j.identj.2020.12.020"},{"key":"8722_CR5987","unstructured":"Faculty of General Dental Practice. Selection criteria for dental radiography. 2018. Available at https:\/\/cgdent.uk\/wp-content\/uploads\/securepdfs\/FGDP-SCDR-ALL-Web.pdf (accessed June 2025)."},{"key":"8722_CR5990","doi-asserted-by":"crossref","unstructured":"Hirshberg A, Berger R, Allon I, Kaplan I. Metastatic tumors to the jaws and mouth. Head Neck Pathol 2014; 8: 463-474.","DOI":"10.1007\/s12105-014-0591-z"},{"key":"8722_CR5992","unstructured":"Kumar J, Vanagundi R, Manchanda A, Mohanty S, Meher R. Radiolucent jaw lesions: imaging approach. Indian J Radiol Imaging 2021; 31: 224-236."},{"key":"8722_CR5994","unstructured":"European Commission. Cone beam CT for dental and maxillofacial radiology - evidence-based guidelines. 2012. Available at https:\/\/op.europa.eu\/en\/publication-detail\/-\/publication\/ec5936c7-5a29-4a93-9b3a-01a5d78d7b2e (accessed June 2025)."},{"key":"8722_CR5999","unstructured":"Bromberg N, Brizuela M. Dental Cone Beam Computed Tomography. Treasure Island: StatPearls Publishing, 2023."},{"key":"8722_CR6001","unstructured":"British Association of Dermatologists. Sun protection fact sheet. 2024. Available at https:\/\/www.skinhealthinfo.org.uk\/wp-content\/uploads\/2024\/05\/Sun-Protection-Fact-Sheet.pdf (accessed October 2024)."},{"key":"8722_CR6004","unstructured":"National Institute for Health and Care Excellence. Melanoma: assessment and management. 2022. Available at https:\/\/www.nice.org.uk\/guidance\/ng14\/chapter\/Recommendations (accessed March 2025)."},{"key":"8722_CR6007","unstructured":"Cancer Research UK. Targeted cancer drugs and immunotherapy for melanoma skin cancer. 2020. Available at https:\/\/www.cancerresearchuk.org\/about-cancer\/melanoma\/treatment\/targeted-cancer-drugs-and-immunotherapy (accessed October 2024)."},{"key":"8722_CR6010","unstructured":"British Association of Dermatologists. Melanoma stage 3. 2019. Available at https:\/\/www.bad.org.uk\/pils\/melanoma-stage-3\/ (accessed March 2025)."},{"key":"8722_CR6013","doi-asserted-by":"crossref","unstructured":"Weber J, Mandala M, Del Vecchio M et al. Adjuvant nivolumab versus ipilimumab in resected Stage iii or iv melanoma. N Engl J Med 2017; 377: 1824-1835.","DOI":"10.1056\/NEJMoa1709030"},{"key":"8722_CR6015","doi-asserted-by":"crossref","unstructured":"Dummer R, Hauschild A, Santinami M et al. Five-year analysis of adjuvant dabrafenib plus trametinib in Stage III melanoma. N Engl J Med 2020; 383: 1139-1148.","DOI":"10.1056\/NEJMoa2005493"},{"key":"8722_CR6018","unstructured":"National Institute for Health and Care Excellence. Pembrolizumab for adjuvant treatment of completely resected stage 3 melanoma. 2022. Available at https:\/\/www.nice.org.uk\/guidance\/ta766\/chapter\/3-Committee-discussion (accessed March 2025)."},{"key":"8722_CR6021","unstructured":"National Institute for Health and Care Excellence. Nivolumab for adjuvant treatment of completely resected melanoma with lymph node involvement or metastatic disease. 2021. Available at https:\/\/www.nice.org.uk\/guidance\/ta684\/chapter\/3-Committee-discussion (accessed March 2025)."},{"key":"8722_CR6024","doi-asserted-by":"crossref","unstructured":"Patel V, Carey B. Pembrolizumab related osteonecrosis of the jaw. Br J Oral Maxillofac Surg 2023; 61: 704-706.","DOI":"10.1016\/j.bjoms.2023.08.241"},{"key":"8722_CR6027","doi-asserted-by":"crossref","unstructured":"Pundole X, Jones A L, Tetzlaff M T et al. Osteonecrosis of the jaw induced by treatment with anti-PD-1 immunotherapy: a case report. Immunotherapy 2020; 12: 1213-1219.","DOI":"10.2217\/imt-2020-0108"}],"container-title":["British Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41415-025-8722-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41415-025-8722-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41415-025-8722-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T08:55:21Z","timestamp":1753433721000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41415-025-8722-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,7,25]]}},"alternative-id":["8722"],"URL":"https:\/\/doi.org\/10.1038\/s41415-025-8722-3","relation":{},"ISSN":["0007-0610","1476-5373"],"issn-type":[{"value":"0007-0610","type":"print"},{"value":"1476-5373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]},"assertion":[{"value":"19 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declaration"}}]}}