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All samples were collected with ethical permission from the Second Affiliated Hospital of Soochow University. The ethics committee\u2019s reference number is JD-LK-2018-071-02. The study was conducted in accordance with the Declaration of Helsinki.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The data supporting the findings of this study can be found in the article, Supplementary Information or available from the corresponding author upon reasonable request.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The research leading to these results has received funding from National Natural Science Foundation of China (grants 81673448 and 81670191), Jiangsu Social Development Project New Clinical Diagnosis and Treatment Technology (BE2019664), Clinical Key Diagnosis and Treatment Technologies in Suzhou City (LCZX201805), The Fifth Phase of \"333 High-level Talents Training Project\" in Jiangsu Province (BRA2018138) and Scientific and Technological Projects of People\u2019s Livelihood in Suzhou City (SS201856).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding information"}}]}}