{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:36:24Z","timestamp":1790141784253,"version":"4.0.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Nutr"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>To examine associations between different types of sweet drinks consumed in early life and adult adiposity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Design<\/jats:title>\n                <jats:p>The analysis involved the secondary analysis of the Avon Longitudinal Study of Parents and Children which followed children from birth to 24 years. Adiposity was measured using Dual-energy X-ray absorptiometry while food frequency questionnaires and diaries monitored diet. \u2018Early exposure\u2019 to sweet drinks was defined as giving a sugar-sweetened beverage or 100% fruit juice (FJ), before two years of age.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Early exposure to cola was associated with higher fat mass, android fat mass and BMI at age 24 years; whereas early exposure to apple juice was associated with lower adult adiposity in females but not males. When age three, exposure to cola was associated with a greater intake of energy, carbohydrates, protein, fat, and less fruit and more fried foods. In contrast, early exposure to apple juice was associated with higher protein and lower fat intakes and consuming more fruits\/vegetables and less fried foods. Parental education, adiposity and socio-economic status influenced whether SSB or FJ was given to a child.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Early drinking of sugar sweetened beverages was associated with a less healthy dietary pattern, and greater adult adiposity. Early drinking of apple juice was associated with a healthier dietary pattern, and lower fat mass in adult females. The choice of drink was associated with social deprivation. As the dietary causes of adult obesity begin in early childhood, increased attention should be given to diet in the first years of life.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1038\/s41430-024-01430-y","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T05:03:42Z","timestamp":1710479022000},"page":"521-526","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Early exposure to sugar sweetened beverages or fruit juice differentially influences adult adiposity"],"prefix":"10.1038","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2170-3827","authenticated-orcid":false,"given":"David","family":"Benton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayley A.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"1430_CR1","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1093\/ajcn\/84.2.274","volume":"84","author":"VS Malik","year":"2006","unstructured":"Malik VS, Schulze MB, Hu FB. Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr 2006;84:274\u201388.","journal-title":"Am J Clin Nutr"},{"key":"1430_CR2","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1177\/1559827608317277","volume":"2","author":"CE O\u2019Neil","year":"2008","unstructured":"O\u2019Neil CE, Nicklas TA. A Review of the Relationship Between 100% Fruit Juice Consumption and Weight in Children and Adolescents. Am J Lifestyle Med. 2008;2:315\u201354.","journal-title":"Am J Lifestyle Med"},{"key":"1430_CR3","doi-asserted-by":"publisher","first-page":"S43","DOI":"10.1111\/jphd.12222","volume":"77","author":"J Frantsve-Hawley","year":"2017","unstructured":"Frantsve-Hawley J, Bader JD, Welsh JA, Wright JT. A systematic review of the association between consumption of sugar-containing beverages and excess weight gain among children under age 12. J Pub Health Dent. 2017;77:S43\u2013S66.","journal-title":"J Pub Health Dent"},{"key":"1430_CR4","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1080\/07315724.2010.10719901","volume":"29","author":"A Pereira","year":"2010","unstructured":"Pereira A, Fulgoni V. Consumption of 100% fruit juice and risk of obesity and metabolic syndrome: findings from the National Health and Nutrition Examination Survey 1999\u20132004. J Am Coll Nutr. 2010;29:625\u201329.","journal-title":"J Am Coll Nutr"},{"key":"1430_CR5","first-page":"1","volume":"28","author":"JR Sakaki","year":"2022","unstructured":"Sakaki JR, Rodriguez NR, Fernandez M-L, Puglisi MJ, Chen M-H, Chun OK. Fruit juice and childhood obesity: a review of epidemiologic studies. Crit Rev Food Sci Nutr. 2022;28:1\u201315.","journal-title":"Crit Rev Food Sci Nutr"},{"key":"1430_CR6","doi-asserted-by":"publisher","first-page":"2526","DOI":"10.1080\/10408398.2015.1012290","volume":"57","author":"L Hebden","year":"2017","unstructured":"Hebden L, O\u2019Leary F, Rangan A, Lie ES, Hirani V, Allman-Farinelli M. Fruit consumption and adiposity status in adults: a systematic review of current evidence. Crit Rev Food Sci Nutr. 2017;57:2526\u201340.","journal-title":"Crit Rev Food Sci Nutr"},{"key":"1430_CR7","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/ije\/dyac230","volume":"52","author":"P Wang","year":"2023","unstructured":"Wang P, Song M, Eliassen AH, Wang M, Giovannucci EL. Dietary patterns and risk of colorectal cancer: a comparative analysis. Int J Epidemiol. 2023;52:96\u2013106.","journal-title":"Int J Epidemiol"},{"key":"1430_CR8","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1038\/ijo.2009.179","volume":"33","author":"AM Paradis","year":"2009","unstructured":"Paradis AM, Godin G, Perusse L, Vohl MC. Associations between dietary patterns and obesity phenotypes. Int J Obes. 2009;33:1419\u201326.","journal-title":"Int J Obes"},{"key":"1430_CR9","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.jneb.2023.10.001","volume":"56","author":"LK English","year":"2024","unstructured":"English LK, Raghavan R, Obbagy JE, Callahan EH, Fultz A, Nevins JEH, et al. Dietary patterns and health: Insights form NESR systematics reviews to inform the Dietary Guidelines for Americans. J Nutr Educ Behav. 2024;56:75\u201387.","journal-title":"J Nutr Educ Behav"},{"key":"1430_CR10","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s13668-013-0071-1","volume":"3","author":"BA Yon","year":"2014","unstructured":"Yon BA, Johnson RK. Dietary Patterns and Sugar-Sweetened Beverage Consumption among Adolescents and Adults. Curr Nutr Rep. 2014;3:43\u201350.","journal-title":"Curr Nutr Rep"},{"key":"1430_CR11","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1093\/ije\/dys064","volume":"42","author":"A Boyd","year":"2013","unstructured":"Boyd A, Golding J, Macleod J, Lawlor DA, Fraser A, Henderson J, et al. Cohort Profile: the \u2018children of the 90s\u2019-the index offspring of the Avon Longitudinal Study of Parents and Children. Int J Epidemiol. 2013;42:111\u201327.","journal-title":"Int J Epidemiol"},{"key":"1430_CR12","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1093\/ije\/dys066","volume":"42","author":"A Fraser","year":"2013","unstructured":"Fraser A, Macdonald-Wallis C, Tilling K, Boyd A, Golding J, Davey Smith G, et al. Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. Int J Epidemiol. 2013;42:97\u2013110.","journal-title":"Int J Epidemiol"},{"key":"1430_CR13","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1017\/S0007114508968264","volume":"100","author":"K Northstone","year":"2008","unstructured":"Northstone K, Emmett PM. Are dietary patterns stable throughout early and mid-childhood? A birth cohort study. Brit J Nut. 2008;100:1069\u201376.","journal-title":"Brit J Nut"},{"key":"1430_CR14","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1079\/PHN2001241","volume":"5","author":"P Emmett","year":"2002","unstructured":"Emmett P, Rogers I, Symes C. Food and nutrient intakes of a population sample of 3-year-old children in the southwest of England in 1996. Public Health Nutr. 2002;5:55\u201364.","journal-title":"Public Health Nutr"},{"key":"1430_CR15","unstructured":"McCance & Widdowson\u2019s the Composition of Foods. 5th ed. Cambridge: Royal Society of Chemistry; 1991."},{"key":"1430_CR16","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1093\/nutrit\/nuv054","volume":"73","author":"PM Emmett","year":"2015","unstructured":"Emmett PM, Jones LR. Diet, growth, and obesity development throughout childhood in the Avon Longitudinal Study of Parents and Children. Nutr Rev. 2015;73:175\u2013206.","journal-title":"Nutr Rev."},{"key":"1430_CR17","doi-asserted-by":"crossref","unstructured":"Elliott P, Cuzick J, English D, Stern R. Geographical and Environmental Epidemiology: Methods for Small-Area Studies. New York: Oxford University Press; 1997.","DOI":"10.1093\/acprof:oso\/9780192622358.001.0001"},{"key":"1430_CR18","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","volume":"42","author":"IPA Harris","year":"2009","unstructured":"Harris IPA, Taylor R, Thielke R, Payne J, Gonzalez JN, Conde JG. Research electronic data capture (REDCap) \u2013 A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inf. 2009;42:377\u201381.","journal-title":"J Biomed Inf"},{"key":"1430_CR19","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1093\/nutrit\/nuz031","volume":"77","author":"D Benton","year":"2019","unstructured":"Benton D, Young HA. Role of fruit juice in achieving the 5-a-day recommendation for fruit and vegetable intake. Nutr Rev. 2019;77:829\u201343.","journal-title":"Nutr Rev"},{"key":"1430_CR20","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1111\/nbu.12526","volume":"46","author":"CHS Ruxton","year":"2021","unstructured":"Ruxton CHS, Derbyshire E, Sievenpiper JL. Pure 100% fruit juices - more than just a source of free sugars? A review of the evidence of their effect on risk of cardiovascular disease, type 2 diabetes and obesity. Nutr Bull. 2021;46:415\u201331.","journal-title":"Nutr Bull"},{"key":"1430_CR21","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1093\/ajcn\/39.1.129","volume":"39","author":"MF Rolland-Cachera","year":"1984","unstructured":"Rolland-Cachera MF, Deheeger M, Bellisle F, Semp\u00e9 M, Guilloud-Bataille M, Patois E. Adiposity rebound in children: a simple indicator for predicting obesity. Am J Clin Nutr. 1984;39:129\u201335.","journal-title":"Am J Clin Nutr"},{"key":"1430_CR22","doi-asserted-by":"crossref","unstructured":"Rolland-Cachera MF, Deheeger M, Maillot M, Bellisle F. Early adiposity rebound: causes and consequences for obesity in children and adults. Int J Obes. 2006;4:S11-17.","DOI":"10.1038\/sj.ijo.0803514"},{"key":"1430_CR23","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1038\/s41366-022-01120-4","volume":"46","author":"J Zhou","year":"2022","unstructured":"Zhou J, Zhang F, Qim X, Li P, Teng Y, Zhang S, et al. Age at adiposity rebound and the relevance for obesity: a systematic review and meta-analysis. Int J Obes. 2022;46:1413.","journal-title":"Int J Obes"},{"key":"1430_CR24","doi-asserted-by":"publisher","first-page":"1081.","DOI":"10.1186\/s12889-016-3752-z","volume":"16","author":"L Doi","year":"2016","unstructured":"Doi L, Williams AJ, Frank J. How has child growth around adiposity rebound altered in Scotland since 1990 and what are the risk factors for weight gain using the Growing Up in Scotland birth cohort 1?. BMC Pub Health. 2016;16:1081.","journal-title":"BMC Pub Health"},{"key":"1430_CR25","doi-asserted-by":"publisher","first-page":"e1001828.","DOI":"10.1371\/journal.pmed.1001828","volume":"12","author":"W Johnson","year":"2016","unstructured":"Johnson W, Li L, Kuh D. How has the age-related process of overweight or obesity development changed over time? Co-ordinated analyses of individual participant data from five United Kingdom birth cohorts. PLoS Med. 2016;12:e1001828.","journal-title":"PLoS Med"},{"key":"1430_CR26","doi-asserted-by":"publisher","first-page":"100986","DOI":"10.1016\/j.mam.2021.100986","volume":"87","author":"J Strain","year":"2022","unstructured":"Strain J, Spaans F, Serhan M, Davidge ST, Connor KL. Programming of weight and obesity across the life course by the maternal metabolic exposome: A systematic review. Mol Asp Med. 2022;87:100986.","journal-title":"Mol Asp Med"},{"key":"1430_CR27","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1186\/s12889-016-3725-2","volume":"16","author":"LP Santos","year":"2016","unstructured":"Santos LP, Assuncao MCF, Matijasevich A, Santos IS, Barros AJD. Dietary intake patterns of children aged 6 years and their association with socioeconomic and demographic characteristics, early feeding practices and body mass index. BMC Pub Heath. 2016;16:1055.","journal-title":"BMC Pub Heath"}],"container-title":["European Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41430-024-01430-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41430-024-01430-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41430-024-01430-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T08:03:22Z","timestamp":1718611402000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41430-024-01430-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,15]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1430"],"URL":"https:\/\/doi.org\/10.1038\/s41430-024-01430-y","relation":{},"ISSN":["0954-3007","1476-5640"],"issn-type":[{"value":"0954-3007","type":"print"},{"value":"1476-5640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,15]]},"assertion":[{"value":"28 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"DB has served on the scientific advisory board of the European Fruit Juice Association, although he was no longer a member when this study was carried out. HY has no conflict of interest to declare.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The present study was conducted according to the guidelines of the Declaration of Helsinki and was approved by ALSPAC Ethics and Law Committee and Local National Health Services Research Ethics Committees. Written informed consent was obtained from all subjects. A fully searchable data dictionary provides details of the data ().","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}