{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T07:10:35Z","timestamp":1794208235616,"version":"4.8.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["PUT736"],"award-info":[{"award-number":["PUT736"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["PUT PRG555"],"award-info":[{"award-number":["PUT PRG555"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["PUTJD817"],"award-info":[{"award-number":["PUTJD817"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["PUT1660"],"award-info":[{"award-number":["PUT1660"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["IUT20-60"],"award-info":[{"award-number":["IUT20-60"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["MOBERA15"],"award-info":[{"award-number":["MOBERA15"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["RITA1\/01-42-03"],"award-info":[{"award-number":["RITA1\/01-42-03"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"EC | European Regional Development Fund","doi-asserted-by":"publisher","award":["2014-2020.4.01.15-0012"],"award-info":[{"award-number":["2014-2020.4.01.15-0012"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"EC | Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["654248"],"award-info":[{"award-number":["654248"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"EC | Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["810645"],"award-info":[{"award-number":["810645"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Hum Genet"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1038\/s41431-020-00760-2","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T10:26:28Z","timestamp":1606127188000},"page":"471-481","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants"],"prefix":"10.1038","volume":"29","author":[{"given":"Liis","family":"Leitsalu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1953-6249","authenticated-orcid":false,"given":"Marili","family":"Palover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6099-1083","authenticated-orcid":false,"given":"Timo T\u00f5nis","family":"Sikka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Reigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mart","family":"Kals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalle","family":"P\u00e4rn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiit","family":"Nikopensius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00f5nu","family":"Esko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Metspalu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peeter","family":"Padrik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1715-3164","authenticated-orcid":false,"given":"Neeme","family":"T\u00f5nisson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"760_CR1","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1038\/s41436-018-0277-0","volume":"21","author":"SM Rowley","year":"2018","unstructured":"Rowley SM, Mascarenhas L, Devereux L, Li N, Amarasinghe KC, Zethoven M, et al. Population-based genetic testing of asymptomatic women for breast and ovarian cancer susceptibility. Genet Med. 2018;21:913\u201322.","journal-title":"Genet Med"},{"key":"760_CR2","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1038\/s41436-018-0311-2","volume":"21","author":"M Alver","year":"2019","unstructured":"Alver M, Palover M, Saar A, L\u00e4ll K, Zekavat SM, T\u00f5nisson N, et al. Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia. Genet Med. 2019;21:1173\u201380.","journal-title":"Genet Med"},{"key":"760_CR3","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1159\/000354105","volume":"16","author":"A Haukkala","year":"2013","unstructured":"Haukkala A, Kujala E, Alha P, Salomaa V, Koskinen S, Swan H, et al. The return of unexpected research results in a biobank study and referral to health care for heritable long QT syndrome. Public Health Genomics. 2013;16:241\u201350.","journal-title":"Public Health Genomics"},{"key":"760_CR4","doi-asserted-by":"publisher","first-page":"e182140","DOI":"10.1001\/jamanetworkopen.2018.2140","volume":"1","author":"K Manickam","year":"2018","unstructured":"Manickam K, Buchanan AH, Schwartz MLB, Hallquist MLG, Williams JL, Rahm AK, et al. Exome sequencing-based screening for BRCA1\/2 expected pathogenic variants among adult biobank participants. JAMA Netw Open. 2018;1:e182140.","journal-title":"JAMA Netw Open"},{"key":"760_CR5","doi-asserted-by":"publisher","first-page":"303","DOI":"10.2217\/pme-2016-0009","volume":"13","author":"L Leitsalu","year":"2016","unstructured":"Leitsalu L, Alavere H, Jacquemont S, Kolk A, Maillard AM, Reigo A, et al. Reporting incidental findings of genomic disorder-associated copy number variants to unselected biobank participants. Per Med. 2016;13:303\u201314.","journal-title":"Per Med"},{"key":"760_CR6","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s10897-018-0288-7","volume":"28","author":"M Vornanen","year":"2018","unstructured":"Vornanen M, Aktan-Collan K, Hallowell N, Konttinen H, Haukkala A. Lay perspectives on receiving different types of genomic secondary findings: a qualitative vignette study. J Genet Couns. 2018;28:343\u201354.","journal-title":"J Genet Couns"},{"key":"760_CR7","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.7717\/peerj.8","volume":"1","author":"U Francke","year":"2013","unstructured":"Francke U, Dijamco C, Kiefer AK, Eriksson N, Moiseff B, Tung JY, et al. Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing. PeerJ. 2013;1:e8.","journal-title":"PeerJ"},{"key":"760_CR8","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1089\/bio.2015.0115","volume":"14","author":"I Budin-lj\u00f8sne","year":"2016","unstructured":"Budin-lj\u00f8sne I, Mascalzoni D, Soini S, Machado H, Kaye J, Bentzen HB. et al. Feedback of individual genetic results to research participants. Biopreserv Biobank. 2016;14:241\u20138.","journal-title":"Biopreserv Biobank"},{"key":"760_CR9","unstructured":"Riigikogu. Human Genes Research Act. 2000. https:\/\/www.riigiteataja.ee\/en\/eli\/508042019001\/consolide."},{"key":"760_CR10","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1093\/hmg\/4.suppl_1.1811","volume":"4","author":"C Szabo","year":"1995","unstructured":"Szabo C, King M. Inherited breast and ovarian cancer. Hum Mol Genet. 1995;4:1811\u20137.","journal-title":"Hum Mol Genet"},{"key":"760_CR11","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1126\/science.7545954","volume":"266","author":"Y Miki","year":"1994","unstructured":"Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 1994;266:66\u201371.","journal-title":"Science"},{"key":"760_CR12","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/378789a0","volume":"378","author":"R Wooster","year":"1995","unstructured":"Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995;378:789\u201392.","journal-title":"Nature"},{"key":"760_CR13","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1097\/01.GIM.0000151155.36470.FF","volume":"7","author":"MR McClain","year":"2005","unstructured":"McClain MR, Palomaki GE, Nathanson KL, Haddow JE. Adjusting the estimated proportion of breast cancer cases associated with BRCA1 and BRCA2 mutations: public health implications. Genet Med. 2005;7:28\u201333.","journal-title":"Genet Med"},{"key":"760_CR14","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1097\/01.ogx.0000499510.12280.54","volume":"71","author":"LC Hartmann","year":"2016","unstructured":"Hartmann LC, Lindor NM. The role of risk-reducing surgery in hereditary breast and ovarian cancer. Obstet Gynecol Surv. 2016;71:598\u20139.","journal-title":"Obstet Gynecol Surv"},{"key":"760_CR15","doi-asserted-by":"publisher","first-page":"2402","DOI":"10.1001\/jama.2017.7112","volume":"317","author":"KB Kuchenbaecker","year":"2017","unstructured":"Kuchenbaecker KB, Hopper JL, Barnes DR, Phillips KA, Mooij TM, Roos-Blom MJ, et al. Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. JAMA. 2017;317:2402\u201316.","journal-title":"JAMA"},{"key":"760_CR16","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/annonc\/mdr373","volume":"22","author":"J Balma\u00f1a","year":"2011","unstructured":"Balma\u00f1a J, D\u00edez O, Rubio IT, Cardoso F. BRCA in breast cancer: ESMO clinical practice guidelines. Ann Oncol. 2011;22:31\u201334.","journal-title":"Ann Oncol"},{"key":"760_CR17","unstructured":"National Comprehensive Cancer Network (NCCN). Breast Cancer Risk Reduction. NCCN Guidelines Version 1.2020."},{"key":"760_CR18","doi-asserted-by":"publisher","first-page":"14205","DOI":"10.1073\/pnas.1415979111","volume":"111","author":"E Gabai-Kapara","year":"2014","unstructured":"Gabai-Kapara E, Lahad A, Kaufman B, Friedman E, Segev S, Renbaum P, et al. Population-based screening for breast and ovarian cancer risk due to BRCA1 and BRCA2. Proc Natl Acad Sci. 2014;111:14205\u201310.","journal-title":"Proc Natl Acad Sci"},{"key":"760_CR19","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1093\/ije\/dyt268","volume":"44","author":"L Leitsalu","year":"2015","unstructured":"Leitsalu L, Haller T, Esko T, Tammesoo M-L, Alavere H, Snieder H, et al. Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu. Int J Epidemiol. 2015;44:1137\u201347.","journal-title":"Int J Epidemiol"},{"key":"760_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13059-016-0974-4","volume":"17","author":"W McLaren","year":"2016","unstructured":"McLaren W, Gil L, Hunt SE, Riat HS, Ritchie GRS, Thormann A, et al. The ensembl variant effect predictor. Genome Biol. 2016;17:1\u201314.","journal-title":"Genome Biol"},{"key":"760_CR21","doi-asserted-by":"publisher","first-page":"1556","DOI":"10.1038\/nprot.2015.105","volume":"10","author":"H Yang","year":"2015","unstructured":"Yang H, Wang K. Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR. Nat Protoc. 2015;10:1556\u201366.","journal-title":"Nat Protoc"},{"key":"760_CR22","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.ajhg.2013.09.002","volume":"93","author":"O Delaneau","year":"2013","unstructured":"Delaneau O, Howie B, Cox AJ, Zagury JF, Marchini J. Haplotype estimation using sequencing reads. Am J Hum Genet. 2013;93:687\u201396.","journal-title":"Am J Hum Genet"},{"key":"760_CR23","doi-asserted-by":"publisher","DOI":"10.1186\/s13742-015-0047-8","volume":"4","author":"CC Chang","year":"2015","unstructured":"Chang CC, Chow CC, Tellier LC, Vattikuti S, Purcell SM, Lee JJ. Second-generation PLINK: rising to the challenge of larger and richer datasets. Gigascience. 2015;4:7.","journal-title":"Gigascience"},{"key":"760_CR24","unstructured":"R Core Team. R: A language and environment for statistical computing. 2018. https:\/\/www.r-project.org\/."},{"key":"760_CR25","doi-asserted-by":"publisher","first-page":"D1062","DOI":"10.1093\/nar\/gkx1153","volume":"46","author":"MJ Landrum","year":"2018","unstructured":"Landrum MJ, Lee JM, Benson M, Brown GR, Chao C, Chitipiralla S, et al. ClinVar: improving access to variant interpretations and supporting evidence. Nucleic Acids Res. 2018;46:D1062\u201367.","journal-title":"Nucleic Acids Res"},{"key":"760_CR26","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/humu.23348","volume":"39","author":"PJ Freeman","year":"2018","unstructured":"Freeman PJ, Hart RK, Gretton LJ, Brookes AJ, Dalgleish R. VariantValidator: accurate validation, mapping, and formatting of sequence variation descriptions. Hum Mutat. 2018;39:61\u201368.","journal-title":"Hum Mutat"},{"key":"760_CR27","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1093\/nar\/29.1.308","volume":"29","author":"S Sherry","year":"2001","unstructured":"Sherry S, Ward M, Kholodov M, Baker J, Phan L, Smigielski E, et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 2001;29:308\u201311.","journal-title":"Nucleic Acids Res"},{"key":"760_CR28","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1038\/gim.2015.30","volume":"17","author":"S Richards","year":"2015","unstructured":"Richards S, Aziz N, Bale S, Bick D, Das S, Gastier-Foster J, et al. Standards and guidelines for the interpretation of sequence variants: A joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med. 2015;17:405\u201324.","journal-title":"Genet Med"},{"key":"760_CR29","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1038\/gim.2014.26","volume":"16","author":"SW Gray","year":"2014","unstructured":"Gray SW, Martins Y, Feuerman LZ, Bernhardt BA, Biesecker BB, Christensen KD, et al. Social and behavioral research in genomic sequencing: approaches from the Clinical Sequencing Exploratory Research Consortium and Measures Working Group. Genet Med. 2014;16:727\u201335.","journal-title":"Genet Med"},{"key":"760_CR30","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/j.2044-8260.1992.tb00997.x","volume":"31","author":"TM Marteau","year":"1992","unstructured":"Marteau TM, Bekker H. The development of a six-item short-form of the state scale of the Spielberger State\u2014Trait Anxiety Inventory (STAI). Br J Clin Psychol. 1992;31:301\u20136.","journal-title":"Br J Clin Psychol"},{"key":"760_CR31","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1177\/0272989X03256005","volume":"23","author":"JC Brehaut","year":"2003","unstructured":"Brehaut JC, O\u2019Connor AM, Wood TJ, Hack TF, Siminoff L, Gordon E, et al. Validation of a decision regret scale. Med Decis Mak. 2003;23:281\u201392.","journal-title":"Med Decis Mak"},{"key":"760_CR32","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1002\/(SICI)1096-8628(19990101)82:1<53::AID-AJMG11>3.0.CO;2-#","volume":"82","author":"M Berkenstadt","year":"1999","unstructured":"Berkenstadt M, Shiloh S, Barkai G, Katznelson MBM, Goldman B. Perceived personal control (PPC): a new concept in measuring outcome of genetic counseling. Am J Med Genet. 1999;82:53\u201359.","journal-title":"Am J Med Genet"},{"key":"760_CR33","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/1098-1004(200008)16:2<123::AID-HUMU4>3.0.CO;2-Y","volume":"16","author":"C Szabo","year":"2000","unstructured":"Szabo C, Masiello A, Ryan JF, Brody LC. The breast cancer information core: database design, structure, and scope. Hum Mutat. 2000;16:123\u201331.","journal-title":"Hum Mutat"},{"key":"760_CR34","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1897-4287-8-4","volume":"8","author":"K Tamboom","year":"2010","unstructured":"Tamboom K, Kaasik K, Ar\u0161avskaja J, Tekkel M, Lilleorg A, Padrik P, et al. BRCA1 mutations in women with familial or early-onset breast cancer and BRCA2 mutations in familial cancer in Estonia. Hered Cancer Clin Pr. 2010;8:4.","journal-title":"Hered Cancer Clin Pr"},{"key":"760_CR35","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1038\/ejhg.2010.203","volume":"19","author":"N Hamel","year":"2011","unstructured":"Hamel N, Feng BJ, Foretova L, Stoppa-Lyonnet D, Narod SA, Imyanitov E, et al. On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations. Eur J Hum Genet. 2011;19:300\u20136.","journal-title":"Eur J Hum Genet"},{"key":"760_CR36","doi-asserted-by":"publisher","unstructured":"Borg \u00c5, Haile RW, Malone KE, Capanu M, Diep A, T\u00f6rngren T, et al. Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: The WECARE study. Hum Mutat 2010;31. https:\/\/doi.org\/10.1002\/humu.21202.","DOI":"10.1002\/humu.21202"},{"key":"760_CR37","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1038\/s41416-018-0127-5","volume":"119","author":"NM Tung","year":"2018","unstructured":"Tung NM, Garber JE. BRCA1\/2 testing: therapeutic implications for breast cancer management. Br J Cancer. 2018;119:141\u201352.","journal-title":"Br J Cancer"},{"key":"760_CR38","doi-asserted-by":"publisher","first-page":"112592","DOI":"10.1016\/j.socscimed.2019.112592","volume":"242","author":"EA Rauscher","year":"2019","unstructured":"Rauscher EA, Dean M, Campbell-Salome G, Barbour JB. \u201cHow do we rally around the one who was positive?\u201d Familial uncertainty management in the context of men managing BRCA-related cancer risks. Soc Sci Med. 2019;242:112592.","journal-title":"Soc Sci Med"},{"key":"760_CR39","doi-asserted-by":"publisher","unstructured":"Menko FH, Jeanson KN, Bleiker EMA, Van Tiggelen CWM, Hogervorst FBL, Jacqueline A, et al. The uptake of predictive DNA testing in 40 families with a pathogenic BRCA1\/BRCA2 variant. An evaluation of the proband-mediated procedure. Eur J Hum Genet. 2020. https:\/\/doi.org\/10.1038\/s41431-020-0618-8.","DOI":"10.1038\/s41431-020-0618-8"},{"key":"760_CR40","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s10689-018-0089-z","volume":"18","author":"FH Menko","year":"2019","unstructured":"Menko FH, ter Stege JA, van der Kolk LE, Jeanson KN, Schats W, Moha DA, et al. The uptake of presymptomatic genetic testing in hereditary breast-ovarian cancer and Lynch syndrome: a systematic review of the literature and implications for clinical practice. Fam Cancer. 2019;18:127\u201335.","journal-title":"Fam Cancer"},{"key":"760_CR41","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1038\/gim.2014.147","volume":"17","author":"H Hampel","year":"2015","unstructured":"Hampel H, Bennett RL, Buchanan A, Pearlman R, Wiesner GL. A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. Genet Med. 2015;17:70\u201387.","journal-title":"Genet Med"},{"key":"760_CR42","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-5783-1","volume":"19","author":"K L\u00e4ll","year":"2019","unstructured":"L\u00e4ll K, Lepamets M, Palover M, Esko T, Metspalu A, T\u00f5nisson N, et al. Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification. BMC Cancer. 2019;19:557.","journal-title":"BMC Cancer"}],"container-title":["European Journal of Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41431-020-00760-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41431-020-00760-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41431-020-00760-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T17:01:06Z","timestamp":1684602066000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41431-020-00760-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,23]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["760"],"URL":"https:\/\/doi.org\/10.1038\/s41431-020-00760-2","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.06.29.20139691","asserted-by":"object"}]},"ISSN":["1018-4813","1476-5438"],"issn-type":[{"value":"1018-4813","type":"print"},{"value":"1476-5438","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,23]]},"assertion":[{"value":"24 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}