{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T14:18:41Z","timestamp":1794493121779,"version":"4.9.1"},"reference-count":132,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T00:00:00Z","timestamp":1572825600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T00:00:00Z","timestamp":1572825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1038\/s41433-019-0633-6","type":"journal-article","created":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T17:04:07Z","timestamp":1572887047000},"page":"60-71","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Treatment choices for newly diagnosed primary open angle and ocular hypertension patients"],"prefix":"10.1038","volume":"34","author":[{"given":"Anurag","family":"Garg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gus","family":"Gazzard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,4]]},"reference":[{"key":"633_CR1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","volume":"90","author":"HA Quigley","year":"2006","unstructured":"Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90:262\u20137.","journal-title":"Br J Ophthalmol."},{"key":"633_CR2","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/S0140-6736(14)62111-5","volume":"385","author":"DF Garway-Heath","year":"2015","unstructured":"Garway-Heath DF, Crabb DP, Bunce C, Lascaratos G, Amalfitano F, Anand N, et al. Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial. Lancet (Lond, Engl). 2015;385:1295\u2013304.","journal-title":"Lancet (Lond, Engl)."},{"key":"633_CR3","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archopht.120.6.701","volume":"120","author":"MA Kass","year":"2002","unstructured":"Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, et al. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol (Chic, Ill : 1960). 2002;120:701\u201313.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR4","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1001\/archopht.120.10.1268","volume":"120","author":"A Heijl","year":"2002","unstructured":"Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol (Chic, Ill : 1960). 2002;120:1268\u201379.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1001\/archopht.121.1.48","volume":"121","author":"MC Leske","year":"2003","unstructured":"Leske MC, Heijl A, Hussein M, Bengtsson B, Hyman L, Komaroff E. Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol (Chic, Ill : 1960). 2003;121:48\u201356.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR6","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0002-9394(98)00223-2","volume":"126","author":"Collaborative Normal-Tension Glaucoma Study Group.","year":"1998","unstructured":"Collaborative Normal-Tension Glaucoma Study Group. Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Am J Ophthalmol. 1998;126:487\u201397.","journal-title":"Am J Ophthalmol."},{"key":"633_CR7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0008-4182(03)80060-1","volume":"38","author":"KF Damji","year":"2003","unstructured":"Damji KF, Behki R, Wang L. Canadian perspectives in glaucoma management: setting target intraocular pressure range. Can J Ophthalmol J Canadien d'ophtalmologie. 2003;38:189\u201397.","journal-title":"Can J Ophthalmol J Canadien d'ophtalmologie"},{"key":"633_CR8","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1001\/jama.2014.3192","volume":"311","author":"RN Weinreb","year":"2014","unstructured":"Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014;311:1901\u201311.","journal-title":"JAMA."},{"issue":"9422","key":"633_CR9","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1016\/S0140-6736(04)16257-0","volume":"363","author":"Robert N Weinreb","year":"2004","unstructured":"Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet. 363:1711\u201320.","journal-title":"The Lancet"},{"key":"633_CR10","doi-asserted-by":"crossref","first-page":"834","DOI":"10.3389\/fnins.2018.00834","volume":"12","author":"M Pietrucha-Dutczak","year":"2018","unstructured":"Pietrucha-Dutczak M, Amadio M, Govoni S, Lewin-Kowalik J, Smedowski A. The role of endogenous neuroprotective mechanisms in the prevention of retinal ganglion cells degeneration. Front Neurosci. 2018;12:834.","journal-title":"Front Neurosci."},{"key":"633_CR11","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.312.7023.71","volume":"312","author":"DL Sackett","year":"1996","unstructured":"Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ (Clin Res ed). 1996;312:71\u20132.","journal-title":"BMJ (Clin Res ed)."},{"key":"633_CR12","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1056\/NEJMra050100","volume":"353","author":"L Osterberg","year":"2005","unstructured":"Osterberg L, Blaschke T. Adherence to medication. New Engl J Med. 2005;353:487\u201397.","journal-title":"New Engl J Med."},{"key":"633_CR13","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3109\/09286589709057101","volume":"4","author":"F Wang","year":"1997","unstructured":"Wang F, Javitt JC, Tielsch JM. Racial variations in treatment for glaucoma and cataract among Medicare recipients. Ophthalmic Epidemiol. 1997;4:89\u2013100.","journal-title":"Ophthalmic Epidemiol."},{"key":"633_CR14","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1001\/archophthalmol.2012.1325","volume":"130","author":"JD Stein","year":"2012","unstructured":"Stein JD, Talwar N, Laverne AM, Nan B, Lichter PR. Racial disparities in the use of ancillary testing to evaluate individuals with open-angle glaucoma. Arch Ophthalmol (Chic, Ill : 1960). 2012;130:1579\u201388.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"issue":"5","key":"633_CR15","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.ophtha.2018.09.034","volume":"126","author":"Lee Jones","year":"2019","unstructured":"Jones L, Garway-Heath DF, Azuara-Blanco A, Crabb DP. Are patient self-reported outcome measures sensitive enough to be used as end points in clinical trials?: evidence from the United Kingdom Glaucoma Treatment Study. Ophthalmology. 2019;126:682\u201389.","journal-title":"Ophthalmology"},{"key":"633_CR16","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/S0140-6736(16)30956-4","volume":"388","author":"A Azuara-Blanco","year":"2016","unstructured":"Azuara-Blanco A, Burr J, Ramsay C, Cooper D, Foster PJ, Friedman DS, et al. Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial. Lancet (Lond, Engl). 2016;388:1389\u201397.","journal-title":"Lancet (Lond, Engl)."},{"issue":"10180","key":"633_CR17","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/S0140-6736(18)32213-X","volume":"393","author":"Gus Gazzard","year":"2019","unstructured":"Gazzard G, Konstantakopoulou E, Garway-Heath D, Garg A, Vickerstaff V, Hunter R, et al. Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial. Lancet. (London, England). 2019;393:1505\u201316.","journal-title":"The Lancet"},{"key":"633_CR18","volume":"18","author":"OK Hee","year":"2018","unstructured":"Hee OK, Thng ZX, Zhu HY, Lamoureux EL. Usage of glaucoma-specific patient-reported outcome measures (PROMs) in the Singapore context: a qualitative scoping exercise. BMC Ophthalmol. 2018;18:197.","journal-title":"BMC Ophthalmol."},{"key":"633_CR19","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1442-9071.2011.02530.x","volume":"39","author":"M Dirani","year":"2011","unstructured":"Dirani M, Crowston JG, Taylor PS, Moore PT, Rogers S, Pezzullo ML, et al. Economic impact of primary open-angle glaucoma in Australia. Clin Exp Ophthalmol. 2011;39:623\u201332.","journal-title":"Clin Exp Ophthalmol"},{"key":"633_CR20","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.ophtha.2009.01.042","volume":"116","author":"HR Taylor","year":"2009","unstructured":"Taylor HR. Glaucoma: where to now? Ophthalmology. 2009;116:821\u20132.","journal-title":"Ophthalmology."},{"key":"633_CR21","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0008-4182(06)80006-2","volume":"41","author":"R Lee","year":"2006","unstructured":"Lee R, Hutnik CM. Projected cost comparison of selective laser trabeculoplasty versus glaucoma medication in the Ontario Health Insurance Plan. Can J Ophthalmol J Canadien d'ophtalmologie. 2006;41:449\u201356.","journal-title":"Can J Ophthalmol J Canadien d'ophtalmologie"},{"key":"633_CR22","doi-asserted-by":"crossref","first-page":"e5745","DOI":"10.1097\/MD.0000000000005745","volume":"95","author":"RA Guedes","year":"2016","unstructured":"Guedes RA, Guedes VM, Gomes CE, Chaoubah A. Maximizing cost-effectiveness by adjusting treatment strategy according to glaucoma severity. Medicine. 2016;95:e5745.","journal-title":"Medicine."},{"key":"633_CR23","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1185\/03007990802379996","volume":"24","author":"LB Cantor","year":"2008","unstructured":"Cantor LB, Katz LJ, Cheng JW, Chen E, Tong KB, Peabody JW. Economic evaluation of medication, laser trabeculoplasty and filtering surgeries in treating patients with glaucoma in the US. Curr Med Res Opin. 2008;24:2905\u201318.","journal-title":"Curr Med Res Opin."},{"key":"633_CR24","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1001\/jamaophthalmol.2015.44","volume":"133","author":"RI Kaplan","year":"2015","unstructured":"Kaplan RI, De Moraes CG, Cioffi GA, Al-Aswad LA, Blumberg DM. Comparative Cost-effectiveness of the Baerveldt implant, trabeculectomy with mitomycin, and medical treatment. JAMA Ophthalmol. 2015;133:560\u20137.","journal-title":"JAMA Ophthalmol."},{"key":"633_CR25","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1080\/13696998.2017.1327439","volume":"20","author":"JP Berdahl","year":"2017","unstructured":"Berdahl JP, Khatana AK, Katz LJ, Herndon L, Layton AJ, Yu TM, et al. Cost-comparison of two trabecular micro-bypass stents versus selective laser trabeculoplasty or medications only for intraocular pressure control for patients with open-angle glaucoma. J Med Econ. 2017;20:760\u20136.","journal-title":"J Med Econ."},{"issue":"4","key":"633_CR26","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1080\/13696998.2019.1572013","volume":"22","author":"Vardhaman Patel","year":"2019","unstructured":"Patel V, Ahmed I, Podbielski D, Falvey H, Murray J, Goeree R. Cost-effectiveness analysis of standalone trabecular micro-bypass stents in patients with mild-to-moderate open-angle glaucoma in Canada. J Med Econ. 2019;22:390-401.","journal-title":"Journal of Medical Economics"},{"key":"633_CR27","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1136\/bjo.2005.088666","volume":"90","author":"CG Owen","year":"2006","unstructured":"Owen CG, Carey IM, De Wilde S, Whincup PH, Wormald R, Cook DG. The epidemiology of medical treatment for glaucoma and ocular hypertension in the United Kingdom: 1994 to 2003. Br J Ophthalmol. 2006;90:861\u20138.","journal-title":"Br J Ophthalmol."},{"issue":"Suppl 1","key":"633_CR28","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/S0039-6257(02)00306-5","volume":"47","author":"RN Weinreb","year":"2002","unstructured":"Weinreb RN, Toris CB, Gabelt BT, Lindsey JD, Kaufman PL. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002;47(Suppl 1):S53\u201364.","journal-title":"Surv Ophthalmol."},{"key":"633_CR29","first-page":"2772","volume":"38","author":"RN Weinreb","year":"1997","unstructured":"Weinreb RN, Kashiwagi K, Kashiwagi F, Tsukahara S, Lindsey JD. Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells. Investigative Ophthalmol Vis Sci. 1997;38:2772\u201380.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR30","doi-asserted-by":"crossref","first-page":"P41","DOI":"10.1016\/j.ophtha.2015.10.053","volume":"123","author":"BE Prum Jr.","year":"2016","unstructured":"Prum BE, Jr., Rosenberg LF, Gedde SJ, Mansberger SL, Stein JD, Moroi SE, et al. Primary open-angle glaucoma preferred practice pattern((R)) guidelines. Ophthalmology. 2016;123:P41\u2013111.","journal-title":"Ophthalmology."},{"key":"633_CR31","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ophtha.2015.09.005","volume":"123","author":"T Li","year":"2016","unstructured":"Li T, Lindsley K, Rouse B, Hong H, Shi Q, Friedman DS, et al. Comparative effectiveness of first-line medications for primary open-angle glaucoma: a systematic review and network meta-analysis. Ophthalmology. 2016;123:129\u201340.","journal-title":"Ophthalmology."},{"issue":"Suppl 1","key":"633_CR32","doi-asserted-by":"crossref","first-page":"S176","DOI":"10.1016\/S0039-6257(02)00304-1","volume":"47","author":"I Grierson","year":"2002","unstructured":"Grierson I, Pfeiffer N, Cracknell KP, Appleton P. Histology and fine structure of the iris and outflow system following latanoprost therapy. Surv Ophthalmol. 2002;47(Suppl 1):S176\u201384.","journal-title":"Surv Ophthalmol."},{"key":"633_CR33","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1136\/bmj.325.7377.1396","volume":"325","author":"JF Kirwan","year":"2002","unstructured":"Kirwan JF, Nightingale JA, Bunce C, Wormald R. Beta blockers for glaucoma and excess risk of airways obstruction: population based cohort study. BMJ (Clin Res ed). 2002;325:1396\u20137.","journal-title":"BMJ (Clin Res ed)"},{"key":"633_CR34","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0002-9394(99)00076-8","volume":"128","author":"CB Toris","year":"1999","unstructured":"Toris CB, Camras CB, Yablonski ME. Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients. Am J Ophthalmol. 1999;128:8\u201314.","journal-title":"Am J Ophthalmol."},{"key":"633_CR35","doi-asserted-by":"crossref","unstructured":"Schmier JK, Hulme-Lowe CK, Covert DW. Adjunctive therapy patterns in glaucoma patients using prostaglandin analogs. Clinical ophthalmology (Auckland, NZ). 2014;8:1097\u2013104.","DOI":"10.2147\/OPTH.S63760"},{"key":"633_CR36","unstructured":"Higginbotham EJ. Considerations in glaucoma therapy: fixed combinations versus their component medications. Clin Ophthalmol (Auckland, NZ). 2010;4:1\u20139."},{"key":"633_CR37","doi-asserted-by":"crossref","first-page":"2067-74.e1-6","DOI":"10.1016\/j.ophtha.2010.03.024","volume":"117","author":"CA Webers","year":"2010","unstructured":"Webers CA, Beckers HJ, Zeegers MP, Nuijts RM, Hendrikse F, Schouten JS. The intraocular pressure-lowering effect of prostaglandin analogs combined with topical beta-blocker therapy: a systematic review and meta-analysis. Ophthalmology. 2010;117:2067-74.e1-6.","journal-title":"Ophthalmology."},{"key":"633_CR38","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ajo.2007.06.012","volume":"144","author":"AL Robin","year":"2007","unstructured":"Robin AL, Novack GD, Covert DW, Crockett RS, Marcic TS. Adherence in glaucoma: objective measurements of once-daily and adjunctive medication use. Am J Ophthalmol. 2007;144:533\u201340.","journal-title":"Am J Ophthalmol."},{"issue":"11 Suppl","key":"633_CR39","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1016\/j.ophtha.2009.06.024","volume":"116","author":"JC Tsai","year":"2009","unstructured":"Tsai JC. A comprehensive perspective on patient adherence to topical glaucoma therapy. Ophthalmology. 2009;116(11 Suppl):S30\u20136.","journal-title":"Ophthalmology."},{"key":"633_CR40","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00061198-200310000-00001","volume":"12","author":"JC Tsai","year":"2003","unstructured":"Tsai JC, McClure CA, Ramos SE, Schlundt DG, Pichert JW. Compliance barriers in glaucoma: a systematic classification. J Glaucoma. 2003;12:393\u20138.","journal-title":"J Glaucoma."},{"key":"633_CR41","first-page":"190","volume":"17","author":"JC Tsai","year":"2006","unstructured":"Tsai JC. Medication adherence in glaucoma: approaches for optimizing patient compliance. Curr Opin Ophthalmol. 2006;17:190\u20135.","journal-title":"Curr Opin Ophthalmol."},{"key":"633_CR42","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.ajo.2005.04.051","volume":"140","author":"BL Nordstrom","year":"2005","unstructured":"Nordstrom BL, Friedman DS, Mozaffari E, Quigley HA, Walker AM. Persistence and adherence with topical glaucoma therapy. Am J Ophthalmol. 2005;140:598\u2013606.","journal-title":"Am J Ophthalmol."},{"key":"633_CR43","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S1543-5946(03)90003-1","volume":"1","author":"R Balkrishnan","year":"2003","unstructured":"Balkrishnan R, Bond JB, Byerly WG, Camacho FT, Anderson RT. Medication-related predictors of health-related quality of life in glaucoma patients enrolled in a medicare health maintenance organization. Am J Geriatr Pharmacother. 2003;1:75\u201381.","journal-title":"Am J Geriatr Pharmacother."},{"key":"633_CR44","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1136\/bjo.2008.151522","volume":"93","author":"MQ Rahman","year":"2009","unstructured":"Rahman MQ, Montgomery DM, Lazaridou MN. Surveillance of glaucoma medical therapy in a Glasgow teaching hospital: 26 years' experience. Br J Ophthalmol. 2009;93:1572\u20135.","journal-title":"Br J Ophthalmol."},{"key":"633_CR45","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1136\/bjo.77.9.590","volume":"77","author":"D Broadway","year":"1993","unstructured":"Broadway D, Grierson I, Hitchings R. Adverse effects of topical antiglaucomatous medications on the conjunctiva. Br J Ophthalmol. 1993;77:590\u20136.","journal-title":"Br J Ophthalmol."},{"key":"633_CR46","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1001\/archopht.1994.01090230060021","volume":"112","author":"DC Broadway","year":"1994","unstructured":"Broadway DC, Grierson I, O'Brien C, Hitchings RA. Adverse effects of topical antiglaucoma medication. II. The outcome of filtration surgery. Arch Ophthalmol (Chic, Ill: 1960). 1994;112:1446\u201354.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR47","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1167\/iovs.17-23212","volume":"59","author":"G Li","year":"2018","unstructured":"Li G, Torrejon KY, Unser AM, Ahmed F, Navarro ID, Baumgartner RA, et al. trabodenoson, an adenosine mimetic with a1 receptor selectivity lowers intraocular pressure by increasing conventional outflow facility in mice. Investigative Ophthalmol Vis Sci. 2018;59:383\u201392.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR48","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1089\/jop.2015.0148","volume":"32","author":"JS Myers","year":"2016","unstructured":"Myers JS, Sall KN, DuBiner H, Slomowitz N, McVicar W, Rich CC, et al. A Dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of 2 and 4 weeks of twice-daily ocular trabodenoson in adults with ocular hypertension or primary open-angle glaucoma. J Ocul Pharmacol Therapeutics: Off J Assoc Ocul Pharmacol Therapeutics. 2016;32:555\u201362.","journal-title":"J Ocul Pharmacol Therapeutics : Off J Assoc Ocul Pharmacol Therapeutics."},{"issue":"15 Suppl","key":"633_CR49","first-page":"S279","volume":"23","author":"JM Liebmann","year":"2017","unstructured":"Liebmann JM, Lee JK. Current therapeutic options and treatments in development for the management of primary open-angle glaucoma. Am J Managed Care. 2017;23(15 Suppl):S279\u2013s92.","journal-title":"Am J Managed Care."},{"key":"633_CR50","doi-asserted-by":"crossref","first-page":"6197","DOI":"10.1167\/iovs.16-20189","volume":"57","author":"R Ren","year":"2016","unstructured":"Ren R, Li G, Le TD, Kopczynski C, Stamer WD, Gong H. Netarsudil increases outflow facility in human eyes through multiple mechanisms. Investigative Ophthalmol Vis Sci. 2016;57:6197\u2013209.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR51","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/IJG.0b013e3182952213","volume":"24","author":"RF Wang","year":"2015","unstructured":"Wang RF, Williamson JE, Kopczynski C, Serle JB. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015;24:51\u20134.","journal-title":"J Glaucoma."},{"key":"633_CR52","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1089\/jop.2014.0146","volume":"31","author":"JW Kiel","year":"2015","unstructured":"Kiel JW, Kopczynski CC. Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits. J Ocul Pharmacol Therapeutics : Off J Assoc Ocul Pharmacol Therapeutics. 2015;31:146\u201351.","journal-title":"J Ocul Pharmacol Therapeutics : Off J Assoc Ocul Pharmacol Therapeutics."},{"key":"633_CR53","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ajo.2017.11.019","volume":"186","author":"JB Serle","year":"2018","unstructured":"Serle JB, Katz LJ, McLaurin E, Heah T, Ramirez-Davis N, Usner DW, et al. Two phase 3 clinical trials comparing the safety and efficacy of netarsudil to timolol in patients with elevated intraocular pressure: rho kinase elevated iop treatment trial 1 and 2 (ROCKET-1 and ROCKET-2). Am J Ophthalmol. 2018;186:116\u201327.","journal-title":"Am J Ophthalmol."},{"key":"633_CR54","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/bjophthalmol-2015-306778","volume":"100","author":"RA Lewis","year":"2016","unstructured":"Lewis RA, Levy B, Ramirez N, Kopczynski CC, Usner DW, Novack GD. Fixed-dose combination of AR-13324 and latanoprost: a double-masked, 28-day, randomised, controlled study in patients with open-angle glaucoma or ocular hypertension. Br J Ophthalmol. 2016;100:339\u201344.","journal-title":"Br J Ophthalmol."},{"key":"633_CR55","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.2147\/OPTH.S103985","volume":"Volume 10","author":"Giancarlo Garcia","year":"2016","unstructured":"Garcia GA, Ngai P, Mosaed S, Lin KY. Critical evaluation of latanoprostene bunod in the treatment of glaucoma. Clin Ophthalmol (Auckland, NZ). 2016;10:2035\u201350.","journal-title":"Clinical Ophthalmology"},{"key":"633_CR56","doi-asserted-by":"crossref","first-page":"5005","DOI":"10.1167\/iovs.14-14515","volume":"55","author":"ME Cavet","year":"2014","unstructured":"Cavet ME, Vittitow JL, Impagnatiello F, Ongini E, Bastia E. Nitric oxide (NO): an emerging target for the treatment of glaucoma. Investigative Ophthalmol Vis Sci. 2014;55:5005\u201315.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR57","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.ophtha.2016.01.019","volume":"123","author":"RN Weinreb","year":"2016","unstructured":"Weinreb RN, Scassellati Sforzolini B, Vittitow J, Liebmann J. Latanoprostene bunod 0.024% versus timolol maleate 0.5% in subjects with open-angle glaucoma or ocular hypertension: the APOLLO study. Ophthalmology. 2016;123:965\u201373.","journal-title":"Ophthalmology."},{"key":"633_CR58","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.ajo.2016.05.012","volume":"168","author":"FA Medeiros","year":"2016","unstructured":"Medeiros FA, Martin KR, Peace J, Scassellati Sforzolini B, Vittitow JL, Weinreb RN. Comparison of latanoprostene bunod 0.024% and TiMolol Maleate 0.5% in open-angle glaucoma or ocular hypertension: the LUNAR study. Am J Ophthalmol. 2016;168:250\u20139.","journal-title":"Am J Ophthalmol."},{"key":"633_CR59","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1007\/s12325-016-0385-7","volume":"33","author":"K Kawase","year":"2016","unstructured":"Kawase K, Vittitow JL, Weinreb RN, Araie M. Long-term safety and efficacy of latanoprostene bunod 0.024% in Japanese subjects with open-angle glaucoma or ocular hypertension: the JUPITER study. Adv Ther. 2016;33:1612\u201327.","journal-title":"Adv Ther."},{"key":"633_CR60","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1001\/archopht.1979.01020010165017","volume":"97","author":"JB Wise","year":"1979","unstructured":"Wise JB, Witter SL. Argon laser therapy for open-angle glaucoma. A pilot study. Arch Ophthalmol (Chic, Ill : 1960). 1979;97:319\u201322.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR61","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0161-6420(82)34807-1","volume":"89","author":"JV Thomas","year":"1982","unstructured":"Thomas JV, Simmons RJ, Belcher CD 3rd. Argon laser trabeculoplasty in the presurgical glaucoma patient. Ophthalmology. 1982;89:187\u201397.","journal-title":"Ophthalmology."},{"key":"633_CR62","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0002-9394(14)77780-3","volume":"96","author":"RF Brubaker","year":"1983","unstructured":"Brubaker RF, Liesegang TJ. Effect of trabecular photocoagulation on the aqueous humor dynamics of the human eye. Am J Ophthalmol. 1983;96:139\u201347.","journal-title":"Am J Ophthalmol."},{"key":"633_CR63","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0014-4835(05)80093-4","volume":"60","author":"MA Latina","year":"1995","unstructured":"Latina MA, Park C. Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions. Exp Eye Res. 1995;60:359\u201371.","journal-title":"Exp Eye Res."},{"key":"633_CR64","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1097\/IJG.0b013e31825af0eb","volume":"22","author":"L Beltran-Agullo","year":"2013","unstructured":"Beltran-Agullo L, Alaghband P, Obi A, Husain R, Lim KS. The effect of selective laser trabeculoplasty on aqueous humor dynamics in patients with ocular hypertension and primary open-angle glaucoma. J Glaucoma. 2013;22:746\u20139.","journal-title":"J Glaucoma."},{"key":"633_CR65","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1136\/bjo.2009.176024","volume":"94","author":"S Goyal","year":"2010","unstructured":"Goyal S, Beltran-Agullo L, Rashid S, Shah SP, Nath R, Obi A, et al. Effect of primary selective laser trabeculoplasty on tonographic outflow facility: a randomised clinical trial. Br J Ophthalmol. 2010;94:1443\u20137.","journal-title":"Br J Ophthalmol."},{"key":"633_CR66","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1167\/iovs.16-20710","volume":"58","author":"V Gulati","year":"2017","unstructured":"Gulati V, Fan S, Gardner BJ, Havens SJ, Schaaf MT, Neely DG, et al. Mechanism of action of selective laser trabeculoplasty and predictors of response. Investigative Ophthalmol Vis Sci. 2017;58:1462\u20138.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR67","first-page":"422","volume":"41","author":"JM Bradley","year":"2000","unstructured":"Bradley JM, Anderssohn AM, Colvis CM, Parshley DE, Zhu XH, Ruddat MS, et al. Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression by IL-1beta and TNFalpha. Investigative Ophthalmol Vis Sci. 2000;41:422\u201330.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR68","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/ceo.12591","volume":"44","author":"JY Lee","year":"2016","unstructured":"Lee JY, Kagan DB, Roumeliotis G, Liu H, Hutnik CM. Secretion of matrix metalloproteinase-3 by co-cultured pigmented and non-pigmented human trabecular meshwork cells following selective laser trabeculoplasty. Clin Exp Ophthalmol. 2016;44:33\u201342.","journal-title":"Clin Exp Ophthalmol"},{"key":"633_CR69","doi-asserted-by":"crossref","first-page":"e20110","DOI":"10.1371\/journal.pone.0020110","volume":"6","author":"A Izzotti","year":"2011","unstructured":"Izzotti A, Longobardi M, Cartiglia C, Rathschuler F, Sacca SC. Trabecular meshwork gene expression after selective laser trabeculoplasty. PLoS ONE. 2011;6:e20110.","journal-title":"PLoS ONE."},{"key":"633_CR70","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1001\/archophthalmol.2010.85","volume":"128","author":"JA Alvarado","year":"2010","unstructured":"Alvarado JA, Katz LJ, Trivedi S, Shifera AS. Monocyte modulation of aqueous outflow and recruitment to the trabecular meshwork following selective laser trabeculoplasty. Arch Ophthalmol (Chic, Ill : 1960). 2010;128:731\u20137.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR71","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0161-6420(00)00660-6","volume":"108","author":"TR Kramer","year":"2001","unstructured":"Kramer TR, Noecker RJ. Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes. Ophthalmology. 2001;108:773\u20139.","journal-title":"Ophthalmology."},{"key":"633_CR72","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.ophtha.2015.04.015","volume":"122","author":"KS Arora","year":"2015","unstructured":"Arora KS, Robin AL, Corcoran KJ, Corcoran SL, Ramulu PY. Use of various glaucoma surgeries and procedures in medicare beneficiaries from 1994 to 2012. Ophthalmology. 2015;122:1615\u201324.","journal-title":"Ophthalmology."},{"key":"633_CR73","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1001\/archopht.121.7.957","volume":"121","author":"S Melamed","year":"2003","unstructured":"Melamed S, Ben Simon GJ, Levkovitch-Verbin H. Selective laser trabeculoplasty as primary treatment for open-angle glaucoma: a prospective, nonrandomized pilot study. Arch Ophthalmol (Chic, Ill : 1960). 2003;121:957\u201360.","journal-title":"Arch Ophthalmol (Chic, Ill : 1960)"},{"key":"633_CR74","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1136\/bjo.2004.052795","volume":"89","author":"M Nagar","year":"2005","unstructured":"Nagar M, Ogunyomade A, O'Brart DP, Howes F, Marshall J. A randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol. 2005;89:1413\u20137.","journal-title":"Br J Ophthalmol."},{"key":"633_CR75","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/00061198-200604000-00009","volume":"15","author":"I McIlraith","year":"2006","unstructured":"McIlraith I, Strasfeld M, Colev G, Hutnik CM. Selective laser trabeculoplasty as initial and adjunctive treatment for open-angle glaucoma. J Glaucoma. 2006;15:124\u201330.","journal-title":"J Glaucoma."},{"key":"633_CR76","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1097\/IJG.0b013e318218287f","volume":"21","author":"LJ Katz","year":"2012","unstructured":"Katz LJ, Steinmann WC, Kabir A, Molineaux J, Wizov SS, Marcellino G. Selective laser trabeculoplasty versus medical therapy as initial treatment of glaucoma: a prospective, randomized trial. J Glaucoma. 2012;21:460\u20138.","journal-title":"J Glaucoma."},{"key":"633_CR77","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1177\/112067210601600116","volume":"16","author":"FS Weinand","year":"2006","unstructured":"Weinand FS, Althen F. Long-term clinical results of selective laser trabeculoplasty in the treatment of primary open angle glaucoma. Eur J Ophthalmol. 2006;16:100\u20134.","journal-title":"Eur J Ophthalmol."},{"key":"633_CR78","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/ceo.12452","volume":"43","author":"DM Woo","year":"2015","unstructured":"Woo DM, Healey PR, Graham SL, Goldberg I. Intraocular pressure-lowering medications and long-term outcomes of selective laser trabeculoplasty. Clin Exp Ophthalmol. 2015;43:320\u20137.","journal-title":"Clin Exp Ophthalmol"},{"key":"633_CR79","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/eye.2013.267","volume":"28","author":"C McAlinden","year":"2014","unstructured":"McAlinden C. Selective laser trabeculoplasty (SLT) vs. other treatment modalities for glaucoma: systematic review. Eye (Lond, Engl). 2014;28:249\u201358.","journal-title":"Eye (Lond, Engl)."},{"key":"633_CR80","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1136\/bjo.2008.148510","volume":"93","author":"M Nagar","year":"2009","unstructured":"Nagar M, Luhishi E, Shah N. Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty. Br J Ophthalmol. 2009;93:497\u2013501.","journal-title":"Br J Ophthalmol."},{"key":"633_CR81","volume":"15","author":"X Li","year":"2015","unstructured":"Li X, Wang W, Zhang X. Meta-analysis of selective laser trabeculoplasty versus topical medication in the treatment of open-angle glaucoma. BMC Ophthalmol. 2015;15:107.","journal-title":"BMC Ophthalmol."},{"key":"633_CR82","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00417-013-2522-1","volume":"252","author":"M Ayala","year":"2014","unstructured":"Ayala M. Intraocular pressure reduction after initial failure of selective laser trabeculoplasty (SLT). Graefe's Arch Clin Exp Ophthalmol=Albrecht von Graefes Arch fur klinische und experimentelle Ophthalmologie. 2014;252:315\u201320.","journal-title":"Graefe's Arch Clin Exp Ophthalmol=Albrecht von Graefes Arch fur klinische und experimentelle Ophthalmologie"},{"key":"633_CR83","doi-asserted-by":"crossref","DOI":"10.1186\/s12886-016-0299-9","volume":"16","author":"BA Francis","year":"2016","unstructured":"Francis BA, Loewen N, Hong B, Dustin L, Kaplowitz K, Kinast R, et al. Repeatability of selective laser trabeculoplasty for open-angle glaucoma. BMC Ophthalmol. 2016;16:128.","journal-title":"BMC Ophthalmol."},{"key":"633_CR84","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/IJG.0b013e31817eee0b","volume":"18","author":"BK Hong","year":"2009","unstructured":"Hong BK, Winer JC, Martone JF, Wand M, Altman B, Shields B. Repeat selective laser trabeculoplasty. J Glaucoma. 2009;18:180\u20133.","journal-title":"J Glaucoma."},{"key":"633_CR85","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1136\/bjophthalmol-2015-307486","volume":"100","author":"J Polat","year":"2016","unstructured":"Polat J, Grantham L, Mitchell K, Realini T. Repeatability of selective laser trabeculoplasty. Br J Ophthalmol. 2016;100:1437\u201341.","journal-title":"Br J Ophthalmol."},{"key":"633_CR86","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4103\/0974-9233.134668","volume":"21","author":"AS Khouri","year":"2014","unstructured":"Khouri AS, Lin J, Berezina TL, Maltzman B, Fechtner RD. Repeat selective laser trabeculoplasty can be effective in eyes with initial modest response. Middle East Afr J Ophthalmol. 2014;21:205\u20139.","journal-title":"Middle East Afr J Ophthalmol"},{"key":"633_CR87","doi-asserted-by":"crossref","first-page":"444","DOI":"10.4103\/2008-322X.150814","volume":"9","author":"AS Khouri","year":"2014","unstructured":"Khouri AS, Lari HB, Berezina TL, Maltzman B, Fechtner RD. Long term efficacy of repeat selective laser trabeculoplasty. J ophthalmic Vis Res. 2014;9:444\u20138.","journal-title":"J ophthalmic Vis Res"},{"key":"633_CR88","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s10792-013-9729-3","volume":"33","author":"N Avery","year":"2013","unstructured":"Avery N, Ang GS, Nicholas S, Wells A. Repeatability of primary selective laser trabeculoplasty in patients with primary open-angle glaucoma. Int Ophthalmol. 2013;33:501\u20136.","journal-title":"Int Ophthalmol."},{"key":"633_CR89","doi-asserted-by":"crossref","unstructured":"Song J. Complications of selective laser trabeculoplasty: a review. Clin Ophthalmol (Auckland, NZ). 2016;10:137\u201343.","DOI":"10.2147\/OPTH.S84996"},{"issue":"1","key":"633_CR90","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/APO.0000000000000175","volume":"5","author":"Jeffrey B. Kennedy","year":"2016","unstructured":"Kennedy JB, SooHoo JR, Kahook MY, Seibold LK. Selective laser trabeculoplasty: an update. Asia-Pacific J Ophthalmol (Philadelphia, Pa). 2016;5:63\u20139.","journal-title":"Asia-Pacific Journal of Ophthalmology"},{"key":"633_CR91","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/ceo.12022","volume":"41","author":"AJ White","year":"2013","unstructured":"White AJ, Mukherjee A, Hanspal I, Sarkies NJ, Martin KR, Shah P. Acute transient corneal endothelial changes following selective laser trabeculoplasty. Clin Exp Ophthalmol. 2013;41:435\u201341.","journal-title":"Clin Exp Ophthalmol"},{"key":"633_CR92","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/IJG.0b013e3181e6668d","volume":"20","author":"M Regina","year":"2011","unstructured":"Regina M, Bunya VY, Orlin SE, Ansari H. Corneal edema and haze after selective laser trabeculoplasty. J Glaucoma. 2011;20:327\u20139.","journal-title":"J Glaucoma."},{"key":"633_CR93","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/ceo.12126","volume":"42","author":"JH Ha","year":"2014","unstructured":"Ha JH, Bowling B, Chen SD. Cystoid macular oedema following selective laser trabeculoplasty in a diabetic patient. Clin Exp Ophthalmol. 2014;42:200\u20131.","journal-title":"Clin Exp Ophthalmol"},{"key":"633_CR94","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1038\/eye.2009.249","volume":"24","author":"DZ Wechsler","year":"2010","unstructured":"Wechsler DZ, Wechsler IB. Cystoid macular oedema after selective laser trabeculoplasty. Eye (Lond, Engl). 2010;24:1113.","journal-title":"Eye (Lond, Engl)."},{"key":"633_CR95","first-page":"193","volume":"27","author":"ZQ Wu","year":"2012","unstructured":"Wu ZQ, Huang J, Sadda S. Selective laser trabeculoplasty complicated by cystoid macular edema: report of two cases. Eye Sci. 2012;27:193\u20137.","journal-title":"Eye Sci."},{"key":"633_CR96","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1097\/IJG.0000000000000259","volume":"25","author":"CA Phillis","year":"2016","unstructured":"Phillis CA, Bourke RD. Bilateral subretinal fluid mimicking subretinal neovascularization within 24 hours after selective laser trabeculoplasty. J Glaucoma. 2016;25:e110\u20134.","journal-title":"J Glaucoma."},{"key":"633_CR97","doi-asserted-by":"crossref","first-page":"409","DOI":"10.3928\/15428877-20080901-10","volume":"39","author":"DY Kim","year":"2008","unstructured":"Kim DY, Singh A. Severe iritis and choroidal effusion following selective laser trabeculoplasty. Ophthalmic Surg, lasers Imaging : Off J Int Soc Imaging Eye. 2008;39:409\u201311.","journal-title":"Ophthalmic Surg, lasers Imaging : Off J Int Soc Imaging Eye"},{"key":"633_CR98","first-page":"295","volume":"92","author":"F Hernandez Pardines","year":"2017","unstructured":"Hernandez Pardines F, Molina Martin JC, Fernandez Montalvo L, Aguirre Balsalobre F. Bilateral choroidal effusion after selective laser trabeculoplasty. Archivos de la Sociedad Espanola de. Oftalmologia. 2017;92:295\u20138.","journal-title":"Oftalmologia."},{"key":"633_CR99","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.survophthal.2014.06.006","volume":"60","author":"MO Wong","year":"2015","unstructured":"Wong MO, Lee JW, Choy BN, Chan JC, Lai JS. Systematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucoma. Surv Ophthalmol. 2015;60:36\u201350.","journal-title":"Surv Ophthalmol"},{"key":"633_CR100","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1016\/j.jcjo.2015.02.006","volume":"50","author":"EF Baser","year":"2015","unstructured":"Baser EF, Akbulut D. Significant peripheral anterior synechiae after repeat selective laser trabeculoplasty. Can J Ophthalmol J canadien d'ophtalmologie. 2015;50:e36\u20138.","journal-title":"Can J Ophthalmol J canadien d'ophtalmologie"},{"key":"633_CR101","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jcjo.2011.07.016","volume":"46","author":"AM Bovell","year":"2011","unstructured":"Bovell AM, Damji KF, Hodge WG, Rock WJ, Buhrmann RR, Pan YI. Long term effects on the lowering of intraocular pressure: selective laser or argon laser trabeculoplasty? Can J Ophthalmol J Canadien d'ophtalmologie. 2011;46:408\u201313.","journal-title":"Can J Ophthalmol J Canadien d'ophtalmologie"},{"key":"633_CR102","doi-asserted-by":"crossref","unstructured":"Rolim de Moura C, Paranhos A, Jr., Wormald R. Laser trabeculoplasty for open angle glaucoma. Cochrane Database Syst Rev. 2007: Cd003919.","DOI":"10.1002\/14651858.CD003919.pub2"},{"key":"633_CR103","first-page":"56","volume":"10","author":"F Ekici","year":"2016","unstructured":"Ekici F, Waisbourd M, Katz LJ. Current and future of laser therapy in the management of glaucoma open. Ophthalmol J. 2016;10:56\u201367.","journal-title":"Ophthalmol J."},{"key":"633_CR104","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1755-3768.2010.02026.x","volume":"90","author":"E Rantala","year":"2012","unstructured":"Rantala E, Valimaki J. Micropulse diode laser trabeculoplasty\u2014180-degree treatment. Acta Ophthalmologica. 2012;90:441\u20134.","journal-title":"Acta Ophthalmologica."},{"key":"633_CR105","doi-asserted-by":"crossref","unstructured":"Fea AM, Bosone A, Rolle T, Brogliatti B, Grignolo FM. Micropulse diode laser trabeculoplasty (MDLT): A phase II clinical study with 12 months follow-up. Clin Ophthalmol (Auckland, NZ). 2008;2:247\u201352.","DOI":"10.2147\/OPTH.S2303"},{"key":"633_CR106","doi-asserted-by":"crossref","first-page":"e2075","DOI":"10.1097\/MD.0000000000002075","volume":"94","author":"JW Lee","year":"2015","unstructured":"Lee JW, Yau GS, Yick DW, Yuen CY. Micropulse laser trabeculoplasty for the treatment of open-angle glaucoma. Medicine. 2015;94:e2075.","journal-title":"Medicine."},{"key":"633_CR107","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.2147\/OPTH.S167102","volume":"Volume 12","author":"Benjamin Abramowitz","year":"2018","unstructured":"Abramowitz B, Chadha N, Kouchouk A, Alhabshan R, Belyea DA, Lamba T. Selective laser trabeculoplasty vs. micropulse laser trabeculoplasty in open-angle glaucoma. Clin Ophthalmol (Auckland, NZ). 2018;12:1599\u2013604.","journal-title":"Clinical Ophthalmology"},{"key":"633_CR108","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3928\/15428877-20090430-07","volume":"40","author":"M Goldenfeld","year":"2009","unstructured":"Goldenfeld M, Melamed S, Simon G, Ben Simon GJ. Titanium:sapphire laser trabeculoplasty versus argon laser trabeculoplasty in patients with open-angle glaucoma. Ophthalmic Surg, lasers Imaging : Off J Int Soc Imaging Eye. 2009;40:264\u20139.","journal-title":"Ophthalmic Surg, lasers Imaging : Off J Int Soc Imaging Eye"},{"key":"633_CR109","doi-asserted-by":"crossref","first-page":"e663","DOI":"10.1097\/IJG.0000000000000317","volume":"25","author":"K Kaplowitz","year":"2016","unstructured":"Kaplowitz K, Wang S, Bilonick R, Oatts JT, Grippo T, Loewen NA. Randomized controlled comparison of titanium-sapphire versus standard Q-switched Nd: YAG laser trabeculoplasty. J Glaucoma. 2016;25:e663\u20137.","journal-title":"J Glaucoma."},{"key":"633_CR110","doi-asserted-by":"crossref","first-page":"e361","DOI":"10.1111\/aos.13280","volume":"95","author":"K Mansouri","year":"2017","unstructured":"Mansouri K, Shaarawy T. Comparing pattern scanning laser trabeculoplasty to selective laser trabeculoplasty: a randomized controlled trial. Acta Ophthalmologica. 2017;95:e361\u2013e5.","journal-title":"Acta Ophthalmologica."},{"key":"633_CR111","first-page":"819","volume":"55","author":"M Belkin","year":"2014","unstructured":"Belkin M, Geffen N, Ofir S, Kaplan Messas A, Barkana Y, Belkin A, et al. Direct trans-scleral selective laser trabeculoplasty (SLT) without a gonioscopy lens. Investigative Ophthalmol Vis Sci. 2014;55:819.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"633_CR112","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/IJG.0000000000000464","volume":"26","author":"N Geffen","year":"2017","unstructured":"Geffen N, Ofir S, Belkin A, Segev F, Barkana Y, Kaplan Messas A, et al. Transscleral selective laser trabeculoplasty without a gonioscopy lens. J Glaucoma. 2017;26:201\u20137.","journal-title":"J Glaucoma."},{"key":"633_CR113","doi-asserted-by":"crossref","unstructured":"Zhang ML, Hirunyachote P, Jampel H. Combined surgery versus cataract surgery alone for eyes with cataract and glaucoma. Cochrane Database Syst Rev. 2015: Cd008671.","DOI":"10.1002\/14651858.CD008671.pub3"},{"key":"633_CR114","doi-asserted-by":"crossref","unstructured":"Burr J, Azuara-Blanco A, Avenell A, Tuulonen A. Medical versus surgical interventions for open angle glaucoma. Cochrane Database Syst Rev. 2012:Cd004399.","DOI":"10.1002\/14651858.CD004399.pub3"},{"key":"633_CR115","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1136\/bjophthalmol-2017-310902","volume":"102","author":"AJ King","year":"2018","unstructured":"King AJ, Fernie G, Azuara-Blanco A, Burr JM, Garway-Heath T, Sparrow JM, et al. Treatment of advanced glaucoma study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma-study protocol. Br J Ophthalmol. 2018;102:922\u20138.","journal-title":"Br J Ophthalmol."},{"key":"633_CR116","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/0002-9394(75)90745-X","volume":"79","author":"PG Watson","year":"1975","unstructured":"Watson PG, Barnett F. Effectiveness of trabeculectomy in glaucoma. Am J Ophthalmol. 1975;79:831\u201345.","journal-title":"Am J Ophthalmol."},{"key":"633_CR117","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.ajo.2011.10.026","volume":"153","author":"SJ Gedde","year":"2012","unstructured":"Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL. Treatment outcomes in the tube versus trabeculectomy (TVT) study after five years of follow-up. Am J Ophthalmol. 2012;153:789\u2013803.e2.","journal-title":"Am J Ophthalmol."},{"key":"633_CR118","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.ophtha.2018.02.003","volume":"125","author":"SJ Gedde","year":"2018","unstructured":"Gedde SJ, Feuer WJ, Shi W, Lim KS, Barton K, Goyal S, et al. Treatment outcomes in the primary tube versus trabeculectomy study after 1 year of follow-up. Ophthalmology. 2018;125:650\u201363.","journal-title":"Ophthalmology."},{"key":"633_CR119","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.ophtha.2014.08.043","volume":"122","author":"DL Budenz","year":"2015","unstructured":"Budenz DL, Barton K, Gedde SJ, Feuer WJ, Schiffman J, Costa VP, et al. Five-Year treatment outcomes in the Ahmed Baerveldt comparison study. Ophthalmology. 2015;122:308\u201316.","journal-title":"Ophthalmology."},{"key":"633_CR120","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1136\/bjo.86.7.748","volume":"86","author":"DPS O'Brart","year":"2002","unstructured":"O'Brart DPS, Rowlands E, Islam N, Noury AMS. A randomised, prospective study comparing trabeculectomy augmented with antimetabolites with a viscocanalostomy technique for the management of open angle glaucoma uncontrolled by medical therapy. Br J Ophthalmol. 2002;86:748\u201354.","journal-title":"Br J Ophthalmol."},{"key":"633_CR121","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1038\/sj.eye.6702726","volume":"23","author":"DF Gilmour","year":"2009","unstructured":"Gilmour DF, Manners TD, Devonport H, Varga Z, Solebo AL, Miles J. Viscocanalostomy versus trabeculectomy for primary open angle glaucoma: 4-year prospective randomized clinical trial. Eye (Lond, Engl). 2009;23:1802\u20137.","journal-title":"Eye (Lond, Engl)."},{"key":"633_CR122","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0161-6420(00)00514-5","volume":"108","author":"C Jonescu-Cuypers","year":"2001","unstructured":"Jonescu-Cuypers C, Jacobi P, Konen W, Krieglstein G. Primary viscocanalostomy versus trabeculectomy in white patients with open-angle glaucoma: a randomized clinical trial. Ophthalmology. 2001;108:254\u20138.","journal-title":"Ophthalmology."},{"key":"633_CR123","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.ophtha.2019.03.006","volume":"126","author":"TW Samuelson","year":"2019","unstructured":"Samuelson TW, Sarkisian SR Jr., Lubeck DM, Stiles MC, Duh YJ, Romo EA, et al. Prospective, randomized, controlled pivotal trial of an Ab interno implanted trabecular micro-bypass in primary open-angle glaucoma and cataract: two-year results. Ophthalmology. 2019;126:811\u201321.","journal-title":"Ophthalmology."},{"key":"633_CR124","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ophtha.2018.05.012","volume":"126","author":"TW Samuelson","year":"2019","unstructured":"Samuelson TW, Chang DF, Marquis R, Flowers B, Lim KS, Ahmed IIK, et al. A Schlemm canal microstent for intraocular pressure reduction in primary open-angle glaucoma and cataract: The HORIZON Study. Ophthalmology. 2019;126:29\u201337.","journal-title":"Ophthalmology."},{"key":"633_CR125","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1016\/j.ophtha.2016.06.032","volume":"123","author":"S Vold","year":"2016","unstructured":"Vold S, Ahmed II, Craven ER, Mattox C, Stamper R, Packer M, et al. Two-Year COMPASS trial results: supraciliary microstenting with phacoemulsification in patients with open-angle glaucoma and cataracts. Ophthalmology. 2016;123:2103\u201312.","journal-title":"Ophthalmology."},{"key":"633_CR126","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/08820538.2019.1581820","volume":"34","author":"A Chatzara","year":"2019","unstructured":"Chatzara A, Chronopoulou I, Theodossiadis G, Theodossiadis P, Chatziralli I. XEN implant for glaucoma treatment: a review of the literature. Semin Ophthalmol. 2019;34:93\u20137.","journal-title":"Semin Ophthalmol."},{"key":"633_CR127","doi-asserted-by":"crossref","first-page":"705915","DOI":"10.1155\/2013\/705915","volume":"2013","author":"LM Brandao","year":"2013","unstructured":"Brandao LM, Grieshaber MC. Update on minimally invasive glaucomasurgery (MIGS) and new implants. J Ophthalmol. 2013;2013:705915.","journal-title":"J Ophthalmol."},{"key":"633_CR128","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1146\/annurev-vision-102016-061422","volume":"3","author":"M Almasieh","year":"2017","unstructured":"Almasieh M, Levin LA. Neuroprotection in glaucoma: animal models and clinical trials. Annu Rev Vis Sci. 2017;3:91\u2013120.","journal-title":"Annu Rev Vis Sci."},{"key":"633_CR129","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1001\/jama.2010.463","volume":"303","author":"LA Levin","year":"2010","unstructured":"Levin LA, Danesh-Meyer HV. Lost in translation: bumps in the road between bench and bedside. JAMA. 2010;303:1533\u20134.","journal-title":"JAMA."},{"key":"633_CR130","doi-asserted-by":"crossref","first-page":"P112","DOI":"10.1016\/j.ophtha.2015.10.055","volume":"123","author":"BE Prum Jr.","year":"2016","unstructured":"Prum BE Jr., Lim MC, Mansberger SL, Stein JD, Moroi SE, Gedde SJ, et al. Primary open-angle glaucoma suspect preferred practice pattern((R)) guidelines. Ophthalmology. 2016;123:P112\u201351.","journal-title":"Ophthalmology."},{"key":"633_CR131","unstructured":"NICE. National Institute for Health and Clinical Excellence. NICE: Guidance on Glaucoma: Diagnosis and management of chronic open angle glaucoma and ocular hypertension: DoH; 2010. www.nice.org.uk\/CG85fullguideline . 2010."},{"key":"633_CR132","doi-asserted-by":"crossref","unstructured":"European Glaucoma Society Terminology and Guidelines for Glaucoma, 4th edn\u2014Chapter 3: Treatment principles and options Supported by the EGS Foundation: Part 1: Foreword; Introduction; Glossary; Chapter 3 Treatment principles and options. Br J Ophthalmol. 2017;101:130\u201395.","DOI":"10.1136\/bjophthalmol-2016-EGSguideline.003"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41433-019-0633-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41433-019-0633-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41433-019-0633-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:08:43Z","timestamp":1684616923000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41433-019-0633-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,4]]},"references-count":132,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["633"],"URL":"https:\/\/doi.org\/10.1038\/s41433-019-0633-6","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,4]]},"assertion":[{"value":"28 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}