{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:39:43Z","timestamp":1790775583753,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Japan Society of Ningen Dock"},{"name":"JSPS KAKENHI"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1038\/s41433-021-01403-6","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T18:07:33Z","timestamp":1612202853000},"page":"3325-3332","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Seasonal fluctuation in intraocular pressure and its associated factors in primary open-angle glaucoma"],"prefix":"10.1038","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6714-2543","authenticated-orcid":false,"given":"Ryo","family":"Terauchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumpei","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Sotozono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Noro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Tatemichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"key":"1403_CR1","first-page":"844","volume":"82","author":"S Resnikoff","year":"2004","unstructured":"Resnikoff S, Pascolini D, Etya\u2019ale D, Kocur I, Pararajasegaram R, Pokharel GP, et al. Global data on visual impairment in the year 2002. Bull World Health Organ. 2004;82:844\u201351.","journal-title":"Bull World Health Organ"},{"key":"1403_CR2","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","volume":"121","author":"YC Tham","year":"2014","unstructured":"Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014;121:2081\u201390.","journal-title":"Ophthalmology"},{"key":"1403_CR3","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1001\/archopht.120.10.1268","volume":"120","author":"A Heijl","year":"2002","unstructured":"Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol (Chic, Ill: 1960). 2002;120:1268\u201379.","journal-title":"Arch Ophthalmol (Chic, Ill: 1960)"},{"key":"1403_CR4","doi-asserted-by":"publisher","first-page":"170","DOI":"10.4103\/jovr.jovr_35_18","volume":"13","author":"JH Kim","year":"2018","unstructured":"Kim JH, Caprioli J. Intraocular pressure fluctuation: is it important? J Ophthalmic Vis Res. 2018;13:170\u20134.","journal-title":"J Ophthalmic Vis Res"},{"key":"1403_CR5","doi-asserted-by":"publisher","first-page":"4398494","DOI":"10.1155\/2017\/4398494","volume":"2017","author":"Y Itoh","year":"2017","unstructured":"Itoh Y, Nakamoto K, Horiguchi H, Ogawa S, Noro T, Sato M, et al. Twenty-four-hour variation of intraocular pressure in primary open-angle glaucoma treated with triple eye drops. J Ophthalmol. 2017;2017:4398494\u20134398494.","journal-title":"J Ophthalmol"},{"key":"1403_CR6","doi-asserted-by":"publisher","first-page":"7817","DOI":"10.1167\/iovs.11-7528","volume":"52","author":"NL Wang","year":"2011","unstructured":"Wang NL, Friedman DS, Zhou Q, Guo L, Zhu D, Peng Y, et al. A population-based assessment of 24-hour intraocular pressure among subjects with primary open-angle glaucoma: the handan eye study. Investigative Ophthalmol Vis Sci. 2011;52:7817\u201321.","journal-title":"Investigative Ophthalmol Vis Sci"},{"key":"1403_CR7","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.ophtha.2006.07.060","volume":"114","author":"B Bengtsson","year":"2007","unstructured":"Bengtsson B, Leske MC, Hyman L, Heijl A. Fluctuation of intraocular pressure and glaucoma progression in the early manifest glaucoma trial. Ophthalmology. 2007;114:205\u20139.","journal-title":"Ophthalmology"},{"key":"1403_CR8","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1136\/bjophthalmol-2013-303980","volume":"98","author":"MC Leidl","year":"2014","unstructured":"Leidl MC, Choi CJ, Syed ZA, Melki SA. Intraocular pressure fluctuation and glaucoma progression: what do we know? Br J Ophthalmol. 2014;98:1315\u20139.","journal-title":"Br J Ophthalmol"},{"key":"1403_CR9","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3341\/kjo.1996.10.1.29","volume":"10","author":"IA Qureshi","year":"1996","unstructured":"Qureshi IA, Xi XR, Lu HJ, Wu XD, Huang YB, Shiarkar E. Effect of seasons upon intraocular pressure in healthy population of China. Korean J Ophthalmol: KJO. 1996;10:29\u201333.","journal-title":"Korean J Ophthalmol: KJO"},{"key":"1403_CR10","first-page":"345","volume":"40","author":"IA Qureshi","year":"1999","unstructured":"Qureshi IA, Xiao RX, Yang BH, Zhang J, Xiang DW, Hui JL. Seasonal and diurnal variations of ocular pressure in ocular hypertensive subjects in Pakistan. Singap Med J. 1999;40:345\u20138.","journal-title":"Singap Med J"},{"key":"1403_CR11","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.ophtha.2012.09.056","volume":"120","author":"SK Gardiner","year":"2013","unstructured":"Gardiner SK, Demirel S, Gordon MO, Kass MA. Seasonal changes in visual field sensitivity and intraocular pressure in the ocular hypertension treatment study. Ophthalmology. 2013;120:724\u201330.","journal-title":"Ophthalmology"},{"key":"1403_CR12","doi-asserted-by":"publisher","first-page":"124","DOI":"10.3390\/diagnostics10020124","volume":"10","author":"M Ayaki","year":"2020","unstructured":"Ayaki M, Negishi K, Yuki K, Kawashima M, Uchino M, Tsubota K. Tear break-up time and seasonal variation in intraocular pressure in a Japanese Population. Diagnostics. 2020;10:124.","journal-title":"Diagnostics"},{"key":"1403_CR13","unstructured":"Mansouri K, Gillmann K, Rao HL, Weinreb RN Weekly and seasonal changes of intraocular pressure measured with an implanted intraocular telemetry sensor. Br J Ophthalmol. 2020. https:\/\/bjo.bmj.com\/content\/early\/2020\/06\/04\/bjophthalmol-2020-315970.info [Epub ahead of print]."},{"key":"1403_CR14","doi-asserted-by":"crossref","unstructured":"Terauchi R, Ogawa S, Noro T, Ito K, Kato T, Tatemichi M et al. Seasonal fluctuation in intraocular pressure and retinal nerve fiber layer thinning in primary open-angle glaucoma. Ophthalmology Glaucoma 2020. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2589419620303057 [Epub ahead of print].","DOI":"10.1016\/j.ogla.2020.11.005"},{"key":"1403_CR15","doi-asserted-by":"publisher","first-page":"e4453","DOI":"10.1097\/MD.0000000000004453","volume":"95","author":"J Cheng","year":"2016","unstructured":"Cheng J, Xiao M, Xu H, Fang S, Chen X, Kong X, et al. Seasonal changes of 24-hour intraocular pressure rhythm in healthy Shanghai population. Medicine. 2016;95:e4453.","journal-title":"Medicine"},{"key":"1403_CR16","first-page":"1641","volume":"111","author":"A Iwase","year":"2004","unstructured":"Iwase A, Suzuki Y, Araie M, Yamamoto T, Abe H, Shirato S, et al. The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology. 2004;111:1641\u20138.","journal-title":"Ophthalmology"},{"key":"1403_CR17","first-page":"563","volume":"17","author":"A Trivli","year":"2019","unstructured":"Trivli A, Koliarakis I, Terzidou C, Goulielmos GN, Siganos CS, Spandidos DA, et al. Normal-tension glaucoma: pathogenesis and genetics. Exp Therapeutic Med. 2019;17:563\u201374.","journal-title":"Exp Therapeutic Med"},{"key":"1403_CR18","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.ophtha.2009.06.058","volume":"117","author":"R Ren","year":"2010","unstructured":"Ren R, Jonas JB, Tian G, Zhen Y, Ma K, Li S, et al. Cerebrospinal fluid pressure in glaucoma: a prospective study. Ophthalmology. 2010;117:259\u201366.","journal-title":"Ophthalmology"},{"key":"1403_CR19","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1878-5085-4-14","volume":"4","author":"J Flammer","year":"2013","unstructured":"Flammer J, Konieczka K, Flammer AJ. The primary vascular dysregulation syndrome: implications for eye diseases. EPMA J. 2013;4:14.","journal-title":"EPMA J"},{"key":"1403_CR20","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/S0002-9394(99)00289-5","volume":"129","author":"C Cursiefen","year":"2000","unstructured":"Cursiefen C, Wisse M, Cursiefen S, J\u00fcnemann A, Martus P, Korth M. Migraine and tension headache in high-pressure and normal-pressure glaucoma. Am J Ophthalmol. 2000;129:102\u20134.","journal-title":"Am J Ophthalmol"},{"key":"1403_CR21","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.ajo.2005.08.037","volume":"141","author":"T Sugiyama","year":"2006","unstructured":"Sugiyama T, Utsunomiya K, Ota H, Ogura Y, Narabayashi I, Ikeda T. Comparative study of cerebral blood flow in patients with normal-tension glaucoma and control subjects. Am J Ophthalmol. 2006;141:394\u20136.","journal-title":"Am J Ophthalmol"},{"key":"1403_CR22","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1136\/bjo.76.5.280","volume":"76","author":"R David","year":"1992","unstructured":"David R, Zangwill L, Briscoe D, Dagan M, Yagev R, Yassur Y. Diurnal intraocular pressure variations: an analysis of 690 diurnal curves. Br J Ophthalmol. 1992;76:280\u20133.","journal-title":"Br J Ophthalmol"},{"key":"1403_CR23","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1136\/bjo.2009.162107","volume":"94","author":"R Varma","year":"2010","unstructured":"Varma R, Hwang LJ, Grunden JW, Bean GW. Using diurnal intraocular pressure fluctuation to assess the efficacy of fixed-combination latanoprost\/timolol versus latanoprost or timolol monotherapy. Br J Ophthalmol. 2010;94:80\u20134.","journal-title":"Br J Ophthalmol"},{"key":"1403_CR24","doi-asserted-by":"publisher","first-page":"341","DOI":"10.3109\/10641968209060747","volume":"4","author":"T Hata","year":"1982","unstructured":"Hata T, Ogihara T, Maruyama A, Mikami H, Nakamaru M, Naka T, et al. The seasonal variation of blood pressure in patients with essential hypertension. Clin Exp hypertension Part A Theory Pract. 1982;4:341\u201354.","journal-title":"Clin Exp hypertension Part A Theory Pract"},{"key":"1403_CR25","doi-asserted-by":"publisher","first-page":"e12492","DOI":"10.14814\/phy2.12492","volume":"3","author":"J Cui","year":"2015","unstructured":"Cui J, Muller MD, Blaha C, Kunselman AR, Sinoway LI. Seasonal variation in muscle sympathetic nerve activity. Physiological Reports. 2015;3:e12492.","journal-title":"Physiological Reports"},{"key":"1403_CR26","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.ajo.2020.03.014","volume":"215","author":"F Mabuchi","year":"2020","unstructured":"Mabuchi F, Mabuchi N, Sakurada Y, Yoneyama S, Kashiwagi K, Iijima H, et al. Genetic variants associated with the onset and progression of primary open-angle glaucoma. Am J Ophthalmol. 2020;215:135\u201340.","journal-title":"Am J Ophthalmol"},{"key":"1403_CR27","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1097\/IJG.0000000000000996","volume":"27","author":"CY Cheung","year":"2018","unstructured":"Cheung CY, Li SL, Chan N, Wong MO, Chan PP, Lai I, et al. Factors associated with long-term intraocular pressure fluctuation in primary angle closure disease: the CUHK PACG Longitudinal (CUPAL) Study. J Glaucoma. 2018;27:703\u201310.","journal-title":"J Glaucoma"},{"key":"1403_CR28","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1038\/eye.2015.231","volume":"30","author":"S Srinivasan","year":"2016","unstructured":"Srinivasan S, Choudhari NS, Baskaran M, George RJ, Shantha B, Vijaya L. Diurnal intraocular pressure fluctuation and its risk factors in angle-closure and open-angle glaucoma. Eye. 2016;30:362\u20138.","journal-title":"Eye"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01403-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01403-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01403-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:12:54Z","timestamp":1684617174000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01403-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1403"],"URL":"https:\/\/doi.org\/10.1038\/s41433-021-01403-6","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"value":"0950-222X","type":"print"},{"value":"1476-5454","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,1]]},"assertion":[{"value":"7 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 February 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}