{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:42:27Z","timestamp":1758634947133,"version":"3.37.3"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Research Foundation of Beijing Friendship Hospital, Capital Medical Universit"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1038\/s41433-021-01427-y","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T21:58:23Z","timestamp":1612907903000},"page":"2624-2630","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Choroidal arterial watershed zone topography and its relationship with maculopathy in highly myopic eyes"],"prefix":"10.1038","volume":"35","author":[{"given":"Jiao","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7877-1620","authenticated-orcid":false,"given":"Jialin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,9]]},"reference":[{"key":"1427_CR1","first-page":"1134.e1","volume":"113","author":"L Xu","year":"2006","unstructured":"Xu L, Wang Y, Li Y, Wang Y, Cui T, Li J, et al. Causes of blindness and visual impairment in urban and rural areas in Beijing: the Beijing eye study. Ophthalmology. 2006;113:1134.e1\u201311.","journal-title":"Ophthalmology"},{"key":"1427_CR2","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.ophtha.2003.05.011","volume":"111","author":"WM Hsu","year":"2004","unstructured":"Hsu WM, Cheng CY, Liu JH, Tsai SY, Chou P. Prevalence and causes of visual impairment in an elderly Chinese population in Taiwan: the Shihpai eye study. Ophthalmology. 2004;111:62\u201369.","journal-title":"Ophthalmology"},{"key":"1427_CR3","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.preteyeres.2015.12.001","volume":"52","author":"K Ohno-Matsui","year":"2016","unstructured":"Ohno-Matsui K, Lai TY, Lai CC, Cheung CM. Updates of pathologic myopia. Prog Retin Eye Res. 2016;52:156\u201387.","journal-title":"Prog Retin Eye Res"},{"key":"1427_CR4","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/S0002-9394(02)01883-4","volume":"134","author":"Y Tano","year":"2002","unstructured":"Tano Y. Pathologic myopia: where are we now? Am J Ophthalmol. 2002;134:645\u201360.","journal-title":"Am J Ophthalmol"},{"key":"1427_CR5","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.preteyeres.2012.04.001","volume":"31","author":"K Neelam","year":"2012","unstructured":"Neelam K, Cheung CM, Ohno-Matsui K, Lai TY, Wong TY. Choroidal neovascularization in pathological myopia. Prog Retin Eye Res. 2012;31:495\u2013525.","journal-title":"Prog Retin Eye Res"},{"key":"1427_CR6","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1016\/j.ophtha.2015.01.025","volume":"122","author":"Y Ikuno","year":"2015","unstructured":"Ikuno Y, Ohno-Matsui K, Wong TY, Korobelnik JF, Vitti R, Li T, et al. Intravitreal aflibercept injection in patients with myopic choroidal neovascularization: The MYRROR study. Ophthalmology. 2015;122:1220\u20137.","journal-title":"Ophthalmology"},{"key":"1427_CR7","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.ophtha.2013.10.023","volume":"121","author":"S Wolf","year":"2014","unstructured":"Wolf S, Balciuniene VJ, Laganovska G, Menchini U, Ohno-Matsui K, Sharma T, et al. RADIANCE: a randomized controlled study of ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia. Ophthalmology. 2014;121:682\u2013.92.e2.","journal-title":"Ophthalmology"},{"key":"1427_CR8","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.preteyeres.2015.10.002","volume":"52","author":"D Ferrara","year":"2016","unstructured":"Ferrara D, Waheed NK, Duker JS. Investigating the choriocapillaris and choroidal vasculature with new optical coherence tomography technologies. Prog Retin Eye Res. 2016;52:130\u201355.","journal-title":"Prog Retin Eye Res"},{"key":"1427_CR9","doi-asserted-by":"publisher","first-page":"889","DOI":"10.2147\/OPTH.S44138","volume":"7","author":"Y Ikuno","year":"2013","unstructured":"Ikuno Y, Fujimoto S, Jo Y, Asai T, Nishida K. Choroidal thinning in high myopia measured by optical coherence tomography. Clin Ophthalmol. 2013;7:889\u201393.","journal-title":"Clin Ophthalmol"},{"key":"1427_CR10","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.ajo.2014.06.004","volume":"158","author":"DY Gewaily","year":"2014","unstructured":"Gewaily DY, Grunwald JE, Pistilli M, Ying GS, Maguire MG, Daniel E, et al. Delayed patchy choroidal filling in the comparison of age-related macular degeneration treatments trials (CATT). Am J Ophthalmol. 2014;158:525\u201331.e2.","journal-title":"Am J Ophthalmol"},{"key":"1427_CR11","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S0002-9394(98)00233-5","volume":"126","author":"TA Ciulla","year":"1998","unstructured":"Ciulla TA, Harris A, Danis RP. Presumed macular choroidal watershed vascular filling, choroidal neovascularization, and systemic vascular disease in patients with age-related macular degeneration. Am J Ophthalmol. 1998;126:153\u20135.","journal-title":"Am J Ophthalmol"},{"key":"1427_CR12","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.2147\/OPTH.S112196","volume":"10","author":"L Bei","year":"2016","unstructured":"Bei L, Lee I, Lee MS, Van Stavern GP, McClelland CM. Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis. Clin Ophthalmol. 2016;10:1573\u20138.","journal-title":"Clin Ophthalmol"},{"key":"1427_CR13","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1038\/sj.eye.6702389","volume":"21","author":"B Feigl","year":"2006","unstructured":"Feigl B, Brown B, Lovie-Kitchin J, Swann P. Functional loss in early age-related maculopathy: the ischaemia postreceptoral hypothesis. Eye. 2006;21:689\u201396.","journal-title":"Eye"},{"key":"1427_CR14","doi-asserted-by":"publisher","first-page":"5856","DOI":"10.1167\/iovs.17-22223","volume":"58","author":"N Hanyuda","year":"2017","unstructured":"Hanyuda N, Akiyama H, Shimoda Y, Mukai R, Sano M, Shinohara Y, et al. Different filling patterns of the choriocapillaris in fluorescein and indocyanine green angiography in primate eyes under elevated intraocular pressure. Invest Ophthalmol Vis Sci. 2017;58:5856\u201361.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1427_CR15","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1167\/iovs.13-12912","volume":"55","author":"MC Burggraaff","year":"2014","unstructured":"Burggraaff MC, Trieu J, de Vries-Knoppert WA, Balk L, Petzold A. The clinical spectrum of microcystic macular edema. Invest Opthalmol Vis Sci. 2014;55:952\u201361.","journal-title":"Invest Opthalmol Vis Sci"},{"key":"1427_CR16","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.ajo.2008.05.032","volume":"146","author":"RF Spaide","year":"2008","unstructured":"Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008;146:496\u2013500.","journal-title":"Am J Ophthalmol"},{"key":"1427_CR17","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/j.1755-3768.2008.01247.x","volume":"87","author":"E Mendrinos","year":"2009","unstructured":"Mendrinos E, Pournaras CJ. Topographic variation of the choroidal watershed zone and its relationship to neovascularization in patients with age-related macular degeneration. Acta Ophthalmol. 2009;87:290\u20136.","journal-title":"Acta Ophthalmol"},{"key":"1427_CR18","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1159\/000309488","volume":"190","author":"K Hayashi","year":"1985","unstructured":"Hayashi K, de Laey JJ. Indocyanine green angiography of submacular choroidal vessels in the human eye. Ophthalmologica. 1985;190:20\u201329.","journal-title":"Ophthalmologica"},{"key":"1427_CR19","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.preteyeres.2017.01.003","volume":"58","author":"RA Linsenmeier","year":"2017","unstructured":"Linsenmeier RA, Zhang HF. Retinal oxygen: from animals to humans. Prog Retin Eye Res. 2017;58:115\u201351.","journal-title":"Prog Retin Eye Res"},{"key":"1427_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02695-z","volume":"7","author":"JE Lee","year":"2017","unstructured":"Lee JE, Ahn KS, Park KH, Pak KY, Kim HJ, Byon IS, et al. Functional end-arterial circulation of the choroid assessed by using fat embolism and electric circuit simulation. Sci Rep. 2017;7:2490.","journal-title":"Sci Rep"},{"key":"1427_CR21","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3341\/kjo.2016.30.4.289","volume":"30","author":"MK Kim","year":"2016","unstructured":"Kim MK, Kim US. Analysis of fundus photography and fluorescein angiography in nonarteritic anterior ischemic optic neuropathy and optic neuritis. Korean J Ophthalmol. 2016;30:289\u201394.","journal-title":"Korean J Ophthalmol"},{"key":"1427_CR22","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/BF00156707","volume":"72","author":"G Giuffr\u00e8","year":"1989","unstructured":"Giuffr\u00e8 G. Main posterior watershed zone of the choroid. Variations of its position in normal subjects. Doc Opthtalmol. 1989;72:175\u201380.","journal-title":"Doc Opthtalmol"},{"key":"1427_CR23","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/S0161-6420(96)30695-7","volume":"103","author":"K Takahashi","year":"1996","unstructured":"Takahashi K, Muraoka K, Kishi S, Shimizu K. Watershed zone in the human peripheral choroid. Ophthalmology. 1996;103:336\u201342.","journal-title":"Ophthalmology"},{"key":"1427_CR24","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1136\/bjo.2009.163535","volume":"94","author":"T Wakabayashi","year":"2010","unstructured":"Wakabayashi T, Ikuno Y. Choroidal filling delay in choroidal neovascularisation due to pathological myopia. Br J Ophthalmol. 2010;94:611\u20135.","journal-title":"Br J Ophthalmol"},{"key":"1427_CR25","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1159\/000309489","volume":"190","author":"K Hayashi","year":"2010","unstructured":"Hayashi K, de Laey JJ. Indocyanine green angiography of choroidal neovascular membranes. Ophthalmologica. 2010;190:30\u201339.","journal-title":"Ophthalmologica"},{"key":"1427_CR26","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1038\/eye.1990.39","volume":"4","author":"SS Hayreh","year":"1990","unstructured":"Hayreh SS. In vivo choroidal circulation and its watershed zones. Eye. 1990;4:273\u201389.","journal-title":"Eye"},{"key":"1427_CR27","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1136\/bjo.46.4.212","volume":"46","author":"SS Hayreh","year":"1962","unstructured":"Hayreh SS. The ophthalmic artery: III. Branches. Br J Ophthalmol. 1962;46:212\u201347.","journal-title":"Br J Ophthalmol"},{"key":"1427_CR28","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1038\/eye.2011.94","volume":"25","author":"YM Kim","year":"2011","unstructured":"Kim YM, Yoon JU, Koh HJ. The analysis of lacquer crack in the assessment of myopic choroidal neovascularization. Eye. 2011;25:937\u201346.","journal-title":"Eye"}],"container-title":["Eye"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01427-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01427-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01427-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T09:11:15Z","timestamp":1629364275000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41433-021-01427-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,9]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["1427"],"URL":"https:\/\/doi.org\/10.1038\/s41433-021-01427-y","relation":{},"ISSN":["0950-222X","1476-5454"],"issn-type":[{"type":"print","value":"0950-222X"},{"type":"electronic","value":"1476-5454"}],"subject":[],"published":{"date-parts":[[2021,2,9]]},"assertion":[{"value":"4 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 December 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}