{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:23:16Z","timestamp":1791890596598,"version":"4.3.4"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Johnson and Johnson Surgical Vision, Inc."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eye"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To evaluate the tolerance to refractive errors of a new purely refractive extended depth of focus (EDF) intraocular lens (IOL), TECNIS PureSee\u2122 IOL, using preclinical and clinical metrics.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Preclinical evaluation included computer simulations of visual acuity (sVA) and dysphotopsia profile of different IOL designs (refractive EDF, diffractive EDF, multifocal, standard, and enhanced monofocals) using an appropriate eye model with and without \u00b10.50 D defocus and\/or +0.75 D of astigmatism. Patients bilaterally implanted with a refractive EDF (Model ZEN00V, TECNIS PureSee\u2122 IOL) or an enhanced monofocal (Model ICB00, TECNIS Eyhance\u2122 IOL) IOL from a prospective, randomized study were included. At the 6-month postoperative visit, uncorrected and corrected distance vision (UDVA and CDVA), visual symptoms, satisfaction and dependency on glasses were evaluated in a subgroup of patients with absolute residual refractive error of &gt;0.25 D in one or both eyes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In the presence of defocus and astigmatism, sVA was comparable for all except the multifocal IOL design. The refractive EDF was more tolerant to myopic outcomes and maintained a monofocal-like dysphotopsia profile with defocus. Binocular logMAR UDVA was \u22120.03\u2009\u00b1\u20090.08 for ZEN00V and \u22120.02\u2009\u00b1\u20090.11 for ICB00. 100% ZEN00V and 97% ICB00 patients did not need glasses and were satisfied with their distance vision. Monocular CDVA, contrast sensitivity and visual symptoms were also similar between both groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The clinical outcomes of the refractive EDF IOL demonstrated high quality distance vision and dysphotopsia comparable to a monofocal IOL, even in the presence of refractive error, thus matching the design expectations of the EDF IOL.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1038\/s41433-024-03040-1","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T12:02:12Z","timestamp":1712318532000},"page":"15-20","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Tolerance to refractive error with a new extended depth of focus intraocular lens"],"prefix":"10.1038","volume":"38","author":[{"given":"Daniel A.","family":"Black","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandra","family":"Bala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6288-0141","authenticated-orcid":false,"given":"Aixa","family":"Alarcon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2011-0807","authenticated-orcid":false,"given":"Srividhya","family":"Vilupuru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,5]]},"reference":[{"key":"3040_CR1","doi-asserted-by":"publisher","first-page":"140","DOI":"10.5318\/wjo.v4.i4.140","volume":"4","author":"P Aristodemou","year":"2014","unstructured":"Aristodemou P, Cartwright NEK, Sparrow JM, Johnston RL. 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The \u2018PURPOSE\u2019 section of the abstract was corrected from \u201cTo evaluate the tolerance to refractive errors of a new purely refractive extended depth of focus (EDF) intraocular lens (IOL) using preclinical and clinical metrics\u201d to \u201cTo evaluate the tolerance to refractive errors of a new purely refractive extended depth of focus (EDF) intraocular lens (IOL), TECNIS PureSee\u2122 IOL, using preclinical and clinical metrics.\u201d Additionally, in the \u2018METHODS\u2019 section of the abstract, the second sentence was corrected from \u201cPatients bilaterally implanted with a refractive EDF (Model ZEN00V) or an enhanced monofocal (Model ICB00) IOL from a prospective, randomized study were included\u201d to \u201cPatients bilaterally implanted with a refractive EDF (Model ZEN00V,TECNIS PureSee\u2122 IOL) or an enhanced monofocal (Model ICB00, TECNIS Eyhance\u2122 IOL) IOL from a prospective, randomized study were included\u201d.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2024","order":8,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":9,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1038\/s41433-024-03422-5","URL":"https:\/\/doi.org\/10.1038\/s41433-024-03422-5","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"DAB: Consultant to, and performs research supported by, Johnson and Johnson Surgical Vision, Inc. CB: Consultant to, and performs research supported by, Johnson and Johnson Surgical Vision, Inc and Alcon. AA: Employee of Johnson & Johnson Surgical Vision, Inc. SV: Employee of Johnson & Johnson Surgical Vision, Inc.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}